Ventricular repolarization lability in children with Kawasaki disease.


:Kawasaki disease (KD) is an acute febrile disease of unknown etiology that develops in children and is sometimes accompanied by myocardial dysfunction and systemic vasculitis. However, myocardial repolarization lability has not yet been fully investigated. Thus, the objective of this study was to evaluate myocardial repolarization lability (QT variability index-QTVI) based on the body surface electrocardiograms in the acute and recovery phases. The subjects were 25 children with acute KD who were hospitalized for treatment. An equal number of age-matched healthy children were selected as controls. The RR-intervals and QT-intervals were measured based on a body surface electrocardiogram of 120 consecutive heartbeats to calculate the QTVI. The QTVI values were then compared with the acute and recovery phases. The relationships between blood biochemistry data and QTVI values were also examined. QTVI was significantly decreased from the acute phase to the recovery phase (P < 0.05) and then recovered to the same level as that of the control. QTVI in the acute phase showed a significant positive relationship with body temperature and C-reactive protein (P <0.05). QTVI was high in the acute phase and was correlated with an inflammatory reaction and became normalized during the recovery phase.


Pediatr Cardiol


Pediatric cardiology


Kuriki M,Fujino M,Tanaka K,Horio K,Kusuki H,Hosoi M,Eryu Y,Kato T,Yamazaki T,Hata T




Has Abstract


2011-04-01 00:00:00












  • A Novel MEF2C Loss-of-Function Mutation Associated with Congenital Double Outlet Right Ventricle.

    abstract::Congenital heart defect (CHD) represents the most prevalent birth defect, and accounts for substantial morbidity and mortality in humans. Aggregating evidence demonstrates the genetic basis for CHD. However, CHD is a heterogeneous disease, and the genetic determinants underlying CHD in most patients remain unknown. In...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lu CX,Wang W,Wang Q,Liu XY,Yang YQ

    更新日期:2018-04-01 00:00:00

  • Personalised Warfarin Dosing in Children Post-cardiac Surgery.

    abstract::Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present prospective, obser...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Al-Metwali BZ,Rivers P,Goodyer L,O'Hare L,Young S,Mulla H

    更新日期:2019-12-01 00:00:00

  • Effect of ventriculotomy on right-ventricular remodeling in hypoplastic left heart syndrome: a histopathological and echocardiography correlation study.

    abstract::The objective of this study was to compare histopathological changes in hypoplastic left heart syndrome right ventricles (RV) of patients undergoing Sano and modified Blalock-Taussig (MBT) shunt and correlate them with echocardiographic findings. Myocardial tissue samples were obtained from hearts with Sano or MBT shu...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Menon SC,Erickson LK,McFadden M,Miller DV

    更新日期:2013-02-01 00:00:00

  • Pressure-regulated volume control vs volume control ventilation in infants after surgery for congenital heart disease.

    abstract::The objective of this investigation was to compare how two modes of positive pressure ventilation affect cardiac output, airway pressures, oxygenation, and carbon dioxide removal in children with congenital heart disease in the immediate postoperative period. The investigation used a one group pretest-post-test study ...

    journal_title:Pediatric cardiology

    pub_type: 临床试验,杂志文章


    authors: Kocis KC,Dekeon MK,Rosen HK,Bandy KP,Crowley DC,Bove EL,Kulik T

    更新日期:2001-05-01 00:00:00

  • Routine Detection of Atrial Fibrillation/Flutter Predicts a Worse Outcome in a Cohort of Tetralogy of Fallot Patients During 23 Years of Follow-Up.

    abstract::Atrial flutter/fibrillation (AFL/AF) is a late complication in adults with repaired tetralogy of Fallot (TOF). Its effects on long-term prognosis are not fully understood. We evaluate the impact of AFL/AF in adults with repaired TOF on global mortality and unplanned hospitalizations during follow-up, and the predictor...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: de Castilhos GM,Ley ALG,Daudt NS,Horowitz ESK,Leiria TLL

    更新日期:2019-06-01 00:00:00

  • Heart rate and systolic time intervals in healthy newborn infants: longitudinal study.

    abstract::To determine the influence of heart rate (HR) on systolic time intervals (STI) in neonates, serial measurements of right ventricular (RVSTI) and left ventricular systolic time intervals (LVSTI) were made on 30 healthy term newborn infants at age 4-8 h, 24-30 h, eight days, and four weeks. STI was related to HR and age...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lindner W,Döhlemann C,Schneider K,Versmold H

    更新日期:1985-01-01 00:00:00

  • An Early Glenn Operation May be Associated with the Later Occurrence of Protein-Losing Enteropathy in Fontan Patients : Association of Early Glenn and Failing Fontan.

    abstract::Protein-losing enteropathy (PLE) and plastic bronchitis (PB) are major causes of long-term mortality after Fontan operation. The objective of this study was to determine early clinical risk factors before the onset of PLE and PB. In a cohort study, 106 Fontan patients between 2005 and 2013 were examined. A median of 5...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Unseld B,Stiller B,Borth-Bruhns T,du Bois F,Kroll J,Grohmann J,Fleck T

    更新日期:2017-08-01 00:00:00

  • Outcomes following electroanatomic mapping and ablation for the treatment of ectopic atrial tachycardia in the pediatric population.

    abstract::Ectopic atrial tachycardia (EAT) is often resistant to medical therapy, with radiofrequency ablation (RFA) being a preferred treatment option. Three-dimensional (3-D) electroanatomic mapping was introduced as a tool for improved substrate localization, although there are no published data with this technology in pedia...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,多中心研究


    authors: Cummings RM,Mahle WT,Strieper MJ,Campbell RM,Costello L,Balfour V,Burchfield A,Frias PA

    更新日期:2008-03-01 00:00:00

  • Age-Dependent Association Between Pre-transplant Blood Transfusion and Outcomes of Pediatric Heart Transplantation.

    abstract::Avoidance of red blood cell (RBC) transfusions in patients awaiting heart transplantation (HTx) has been suggested to minimize the risk of allosensitization. Although recent studies have suggested that an immature immune system in younger HTx recipients may reduce risks associated with RBC transfusion, the role of age...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: McKee C,Tumin D,Alevriadou BR,Nicol KK,Yates AR,Hayes D Jr,Tobias JD

    更新日期:2018-04-01 00:00:00

  • Circulating Progenitor Cells and Childhood Cardiovascular Disease.

    abstract::Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowle...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: Kort EJ,Croskey L,Scibienski T,Rajasekaran S,Jovinge S

    更新日期:2016-02-01 00:00:00

  • Fontan-type operation for correcting complex congenital defects in a criss-cross heart.

    abstract::Three cases of criss-cross heart with severe and complex congenital defects are reported. Precise preoperative diagnosis of the morphologic abnormalities made it possible to choose an optimal method of surgical treatment: all patients successfully underwent a Fontan-type surgical procedure. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Podzolkov VP,Ivanitsky AV,Makhachev OA,Alekian BG,Chiaureli MR,Ragimov FR

    更新日期:1990-04-01 00:00:00

  • Accessory pathway ablation in a 6-year-old girl using remote magnetic navigation as an alternative to cryoablation.

    abstract::A 6-year-old girl with evidence of a parahisian accessory pathway on a baseline electrocardiogram underwent successful catheter ablation using magnetic navigation. Magnetic remote controlled ablation eliminated the parahisian pathway with the first radiofrequency application. A second anterolaterally located concealed...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Mantziari L,Rigby M,Till J,Ernst S

    更新日期:2013-03-01 00:00:00

  • Myocardial perfusion abnormalities in patients occurring more than 1 year after successful univentricular (Fontan surgery) and biventricular repair (complete repair of tetralogy of Fallot).

    abstract::The outcome of children born with cyanotic congenital heart disease has markedly improved over the years. Follow up is recommended for most post-operated cases as complications may occur over long term. One of the complications is the development of ventricular dysfunction, often seen after a successful Fontan surgery...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Priyadarshini A,Saxena A,Patel C,Paul VK,Lodha R,Airan B

    更新日期:2013-04-01 00:00:00

  • Aneurysm of the ventricular membranous septum: serial echocardiographic studies.

    abstract:OBJECTIVES:The aim of this article is to examine the frequency, timing of formation of aneurysm of the ventricular membranous septum (AVMS), and prognosis in patients with a perimembranous ventricular septal defect (VSD). PATIENTS:One hundred forty-eight patients were diagnosed with a perimembranous VSD within 90 days...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Miyake T,Shinohara T,Nakamura Y,Fukuda T,Tasato H,Toyohara K,Tanihira Y

    更新日期:2004-07-01 00:00:00

  • Dual-Chamber Stimulation with Single-Lead VDD Pacing System in Mustard Surgery.

    abstract::Sinus node disease is a problem encountered in patients after the Mustard surgery, requiring a pacemaker implantation. The knowledge of the complexity anatomy is crucial because of the possible challenges associated with this procedure. We report a case of a 24-year-old woman presented with symptomatic bradycardia, in...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Cabrera-Ortega M,Díaz-Ramírez F,Benítez-Ramos DB

    更新日期:2015-08-01 00:00:00

  • Acute occlusion of a simple aortic coarctation presenting as abdominal angina.

    abstract::A 9-year-old boy whose past history was remarkable for a heart murmur was diagnosed with abdominal angina due to acute occlusion of a simple coarctation of the aorta. Using a single cross-clamp, we accomplished an end-to-end anastomosis after resection of the coarctation. Paradoxical hypertension and abdominal angina ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Ingu A,Morikawa M,Fuse S,Abe T

    更新日期:2003-09-01 00:00:00

  • Prognostic Value of Serum Apelin Level in Children with Heart Failure Secondary to Congenital Heart Disease.

    abstract::Apelin is an endogenous inotrope that decreased in heart failure (HF). We aimed to evaluate the prognostic value of its level in children with HF due to congenital heart disease (CHD). Sixty children with HF due to CHD were included as a patient group. Sixty healthy children matched for age, sex, and weight served as ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: El Amrousy D,El-Mahdy H

    更新日期:2018-08-01 00:00:00

  • Longer Ischemic Time is Associated with Increased Ventricular Stiffness as Measured by Pressure-Volume Loop Analysis in Pediatric Heart Transplant Recipients.

    abstract:BACKGROUND:The purpose of this study was to investigate the associations between clinical factors and cardiac function as measured by pressure-volume loops (PVLs) in a pediatric heart transplant cohort. METHODS:Patients (age < 20 years) who underwent heart transplantation presenting for a clinically indicated catheter...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Schroeder LW,Chowdhury SM,Burnette AL,Kavarana MN,Hamilton Baker G,Savage AJ,Atz AM,Butts RJ

    更新日期:2018-02-01 00:00:00

  • Anterosuperior diverticula of the right ventricle: morphological spectrum and long-term outcome of a distinct cardiac anomaly.

    abstract::Right-ventricular diverticula (RVD), although rare, have particular characteristics. Our study describes the morphology of anterosuperior diverticula of the right ventricle (RV) and patient outcome for this anomaly. Retrospective analysis was performed on all patients with anterosuperior RVD diagnosed in two tertiary ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Wiegand G,Rauch R,Singer H,Koch A,Hofbeck M

    更新日期:2014-08-01 00:00:00

  • Improved prenatal detection of congenital heart disease in an integrated health care system.

    abstract::The reported prenatal detection rates (PDRs) for significant congenital heart disease (sCHD) have been suboptimal, even in the current era. Changes in prenatal ultrasound policy and training may lead to improved prenatal detection of sCHD. This study analyzed the results of a policy to assess fetal cardiac outflow tra...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Levy DJ,Pretorius DH,Rothman A,Gonzales M,Rao C,Nunes ME,Bendelstein J,Mehalek K,Thomas A,Nehlsen C,Ehr J,Burchette RJ,Sklansky MS

    更新日期:2013-03-01 00:00:00

  • Transient third-degree atrioventricular block in a 4-year-old child with familial dysautonomia.

    abstract::The case of a transient third degree atrioventricular block in a 4-year-old patient with familial dysautonomia is reported. A review of the literature follows with analysis of the significance of arrhythmias in the natural history of the patient with familial dysautonomia. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Rutkowski M,Axelrod FB,Danilowicz D

    更新日期:1992-07-01 00:00:00

  • Prenatally Diagnosed Ventricular Inversion, Restrictive Ventricular Septal Defect, Pulmonary Stenosis, Hypertensive Left Ventricle and Double Outlet Right Ventricle: Case Report and Literature Review.

    abstract::We herein describe, for the first time, the fetal presentation of a case of ventricular inversion, restrictive ventricular septal defect, pulmonary stenosis, hypertensive left ventricle and double outlet right ventricle at 34 weeks of gestational age. Postnatal echocardiography confirmed the prenatal diagnosis. The pa...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: El-Asmar JM,Degheili JA,Al-Halabi E,Sklansky M

    更新日期:2019-01-01 00:00:00

  • A case of renal artery stenosis in a child confirmed by multidetector computed tomographic angiography.

    abstract::Renovascular hypertension is an uncommon disease, but it causes 5-10% of all childhood hypertension. The most common cause of renal artery stenosis is fibromuscular dysplasia, resulting in at least 60% of renovascular hypertension cases. This report describes a case of a renal artery stenosis confirmed by multidetecto...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Kim HJ,Son JS,Kim KS

    更新日期:2011-06-01 00:00:00

  • Warfarin anticoagulation after congenital heart surgery at a large children's hospital.

    abstract::Management of warfarin in pediatric patients remains a clinical challenge. Warfarin may be administered after congenital heart surgery, and the risks of morbidity can be high. Currently, no data exist to describe the initiation of warfarin and the risk factors for morbidity in post-congenital heart surgery patients. T...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lowry AW,Moffett BS,Moodie D,Knudson JD

    更新日期:2012-12-01 00:00:00

  • Valve Replacement in Children with Single Ventricle Physiology.

    abstract::Severe atrioventricular valve (AVV) or semilunar valve (SLV) regurgitation in the setting of a single ventricle physiology may proceed to valve replacement if repair strategies fail. Outcome data for these children are limited. We present transplant-free survival of a case series of children with single ventricle phys...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Alshami N,Sarvestani AL,Thomas AS,St Louis J,Kochilas L,Raghuveer G

    更新日期:2020-01-01 00:00:00

  • Immunosuppressive therapy of chronic myocarditis in children: three cases and the design of a randomized prospective trial of therapy.

    abstract::Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone res...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Schmaltz AA,Demel KP,Kallenberg R,Neudorf U,Kandolf R,Klingel K,Bültmann B

    更新日期:1998-05-01 00:00:00

  • Right Ventricular Mechanical Dyssynchrony in Hypoplastic Left Heart Syndrome: Correlation with Systolic Function and QRS Duration.

    abstract::The single right ventricle (RV) in hypoplastic left heart syndrome (HLHS) often develops systolic dysfunction with time and this affects prognosis. Mechanical dyssynchrony has been reported in HLHS but has not consistently correlated with systolic function or electrical dyssynchrony. The aims of this study were to ass...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Zaidi SJ,Penk J,Cui VW,Roberson DA

    更新日期:2019-06-01 00:00:00

  • Can Abbreviated Cardiac Magnetic Resonance Imaging Adequately Support Clinical Decision Making After Repair of Tetralogy of Fallot?

    abstract::Quantification of pulmonary regurgitation (PR), pulmonary flow distribution, and ventricular function is important for clinical surveillance in repaired Tetralogy of Fallot (TOF). Cardiovascular magnetic resonance (CMR) is the established reference, but cost, test duration, and patient discomfort are potential limitat...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: House AV,Muthurangu V,Spanel AJ,Danford DA,Mir B,Schuster A,Hsu H,Kutty S

    更新日期:2019-03-01 00:00:00

  • Carney complex presenting with Raynaud's phenomenon and erythematous macules of the extremities.

    abstract::A 12-year-old male presented with a 6-week history of apparent digital vasculitis with color changes of the distal fingers and erythematous macules of the palms and soles. Physical examination revealed skin findings of Carney complex and an abnormal cardiac examination. Echocardiography demonstrated a large left atria...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Mirkinson LJ,Ratnayaka K,Sable CA,Gaskin PR

    更新日期:2006-03-01 00:00:00

  • Cerebral near-infrared spectroscopy correlates to vital parameters during cardiopulmonary bypass surgery in children.

    abstract::Near-infrared spectroscopy (NIRS) can monitor changes in cerebral regional oxygen saturation (rSO2) and tissue hemoglobin content (HbT). The relation between cerebral NIRS readings and vital parameters has not been analyzed before at a fine temporal scale. This study analyzed this relation during cardiopulmonary bypas...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Menke J,Möller G

    更新日期:2014-01-01 00:00:00