A prospective investigation of swallowing, nutrition, and patient-rated functional impact following altered fractionation radiotherapy with concomitant boost for oropharyngeal cancer.


:Altered fractionation radiotherapy for head and neck cancer has been associated with improved locoregional control, overall survival, and heightened toxicity compared with conventional treatment. Swallowing, nutrition, and patient-perceived function for altered fractionation radiotherapy with concomitant boost (AFRT-CB) for T1-T3 oropharyngeal squamous cell carcinoma (SCC) have not been previously reported. Fourteen consecutive patients treated with AFRT-CB for oropharyngeal SCC were recruited from November 2006 to August 2009 in a tertiary hospital in Brisbane, Australia. Swallowing, nutrition, and patient-perceived functional impact assessments were conducted pretreatment, at 4-6 weeks post-treatment, and at 6 months post-treatment. Deterioration from pretreatment to 4-6 weeks post-treatment in swallowing, nutrition, and functional impact was evident, likely due to the heightened toxicity associated with AFRT-CB. There was significant improvement at 6 months post-treatment in functional swallowing, nutritional status, patient-perceived swallowing, and overall function, consistent with recovery from acute toxicity. However, weight and patient perception of physical function and side effects remained significantly worse than pretreatment scores. The ongoing deficits related to weight and patient-perceived outcomes at 6 months revealed that this treatment has a long-term impact on function possibly related to the chronic effects of AFRT-CB.






Cartmill B,Cornwell P,Ward E,Davidson W,Porceddu S




Has Abstract


2012-03-01 00:00:00












  • The effect of barium on perceptions of taste intensity and palatability.

    abstract::Barium may affect the perception of taste intensity and palatability. Such differences are important considerations in the selection of dysphagia assessment strategies and interpretation of results. Eighty healthy women grouped by age (younger, older) and genetic taste status (supertaster, nontaster) rated intensity a...


    pub_type: 杂志文章


    authors: Dietsch AM,Solomon NP,Steele CM,Pelletier CA

    更新日期:2014-02-01 00:00:00

  • Dysphagia--ingestion or deglutition?: a proposed paradigm.

    abstract::The current classifications of dysphagia are based on local structural or central nervous system pathology causing dysfunction of the aerodigestive tract. The result is a clinical science grounded in the analysis of the swallow with its lingual, pharyngeal, and esophageal stages. Adding bolus preparation to the swallo...


    pub_type: 杂志文章,评审


    authors: Leopold NA,Kagel MC

    更新日期:1997-10-01 00:00:00

  • A study of the early stage of Dysphagia in amyotrophic lateral sclerosis.

    abstract::In amyotrophic lateral sclerosis (ALS) patients, dysphagia eventually occurs independent of time of onset. We studied dysphagia conditions in the early stage of ALS, principally at the oral phase. Videofluoroscopic and manometric studies were conducted on 11 patients (5 males and 6 females, age range = 47-82 years) wh...


    pub_type: 杂志文章


    authors: Kawai S,Tsukuda M,Mochimatsu I,Enomoto H,Kagesato Y,Hirose H,Kuroiwa Y,Suzuki Y

    更新日期:2003-01-01 00:00:00

  • Isolated proximal esophageal injury from blunt trauma: endoscopic stricture dilatation.

    abstract::Blunt neck trauma can cause isolated esophageal injuries that may be difficult to recognize. A high index of suspicion is necessary for optimal identification and management of this condition. We report a case of blunt esophageal trauma resulting from a motor vehicle accident that was initially unrecognized until the ...


    pub_type: 杂志文章


    authors: Pineau BC,Ott DJ

    更新日期:2003-10-01 00:00:00

  • Esophageal motility, heartburn, and gastroesophageal reflux: variations in clinical presentation of esophageal dysphagia.

    abstract::Dysphagia is a potentially important symptom, often leading to the finding of an anatomical or motility disorder of the esophagus. Dysphagia and heartburn represent two of the most common symptoms associated with esophageal motility disorders. To explore the relationship of symptomatic esophageal dysphagia and heartbu...


    pub_type: 杂志文章


    authors: Decktor DL,Allen ML,Robinson M

    更新日期:1990-01-01 00:00:00

  • Prevalence of aspiration and laryngeal penetration in patients with unilateral vocal fold motion impairment.

    abstract::The adverse consequences of aspiration in regard to patient health and quality of life are well documented. It is generally accepted that the probability of aspiration is increased in patients with unilateral vocal fold motion impairment, however, the incidence and proposed mechanism of aspiration vary depending on th...


    pub_type: 杂志文章


    authors: Heitmiller RF,Tseng E,Jones B

    更新日期:2000-10-01 00:00:00

  • The effect of different catheter balloon dilatation modes on cricopharyngeal dysfunction in patients with dysphagia.

    abstract::The primary aim of this study was to investigate the outcomes of two different modes (active and passive) of balloon dilatation therapy on cricopharyngeal dysfunction (CPD). Thirty-eight CPD patients with neurological disorders were recruited between 2006 and 2010. Twenty-one of them received active balloon dilatation...


    pub_type: 杂志文章


    authors: Dou Z,Zu Y,Wen H,Wan G,Jiang L,Hu Y

    更新日期:2012-12-01 00:00:00

  • Assessment of swallowing by oropharyngoesophageal scintigraphy in patients with amyotrophic lateral sclerosis.

    abstract::Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disease in adults, and dysphagia is one of its most frequent and disabling symptoms. Oropharyngoesophageal scintigraphy (OPES) permits a functional and semiquantitative study of the various stages of swallowing. We studied 28 ALS patients...


    pub_type: 杂志文章


    authors: Fattori B,Grosso M,Bongioanni P,Nacci A,Cristofani R,AlSharif A,Licitra R,Matteucci F,Rossi B,Rubello D,Ursino F,Mariani G

    更新日期:2006-10-01 00:00:00

  • Radiation dose in videofluoroscopic swallow studies.

    abstract::Videofluoroscopy has become an increasingly important armament in the investigation and assessment of swallowing disorders. However, very little work has been published on the radiation dose used in such examinations and currently there is no national diagnostic reference level in the United Kingdom. Videofluoroscopy ...


    pub_type: 杂志文章


    authors: Zammit-Maempel I,Chapple CL,Leslie P

    更新日期:2007-01-01 00:00:00

  • Manofluorography in the evaluation of oropharyngeal dysphagia.

    abstract::Manofluorography, that is, the concurrent use of manometry and videofluorography for the evaluation of pharyngeal dysphagia, has not been widely used clinically, partially because of various limitations of conventional manometry. Technological advancements in recent years have led to substantial improvements in manome...


    pub_type: 杂志文章,评审


    authors: Nativ-Zeltzer N,Kahrilas PJ,Logemann JA

    更新日期:2012-06-01 00:00:00

  • Neuroplasticity and swallowing.

    abstract::Recent research has suggested that the central nervous system controlling swallowing can undergo experience-dependent plasticity. Moreover, swallowing neuroplastic change may be associated with behavioural modulation. This article presents research evidence suggesting that nonbehavioural and behavioural interventions,...


    pub_type: 杂志文章,评审


    authors: Martin RE

    更新日期:2009-06-01 00:00:00

  • Bolus location at the initiation of the pharyngeal stage of swallowing in healthy older adults.

    abstract::This study characterized the vertical position of the bolus head at the onset of the pharyngeal swallow in healthy older adults. Lateral-view videofluoroscopic (VF) images were obtained from ten healthy volunteers (age-71.6 +/- 7.5 years, mean+/- SD) as they swallowed 5-cc thin liquid barium aliquots. For each swallow...


    pub_type: 杂志文章


    authors: Stephen JR,Taves DH,Smith RC,Martin RE

    更新日期:2005-10-01 00:00:00

  • Potential for Volitional Control of Resting Pressure at the Upper Oesophageal Sphincter in Healthy Individuals.

    abstract::Resting pressure at the upper oesophageal sphincter (UOS) has been reported to be susceptible to factors such as emotional stress or respiration. This exploratory study investigated the potential for behavioural modulation of UOS resting pressure in healthy adults to increase our understanding of volitional control of...


    pub_type: 杂志文章


    authors: Winiker K,Gozdzikowska K,Guiu Hernandez E,Kwong SL,Macrae P,Huckabee ML

    更新日期:2020-06-18 00:00:00

  • Patient Adherence to Dysphagia Recommendations: A Systematic Review.

    abstract::Patient adherence to treatment recommendations is an important issue for healthcare providers, in a multitude of specialties, and is critical when assessing the efficacy and effectiveness of a particular treatment approach. Patients who have swallowing impairment often require complex and specific interventions requir...


    pub_type: 杂志文章


    authors: Krekeler BN,Broadfoot CK,Johnson S,Connor NP,Rogus-Pulia N

    更新日期:2018-04-01 00:00:00

  • Acoustic technique for determining timing of velopharyngeal closure in swallowing.

    abstract::A pure tone sound source was introduced at a nostril and monitored by a miniature accelerometer on the throat. During velopharyngeal closure in a swallow, the pure tone component in the accelerometer signal was attenuated. Throat accelerometer recordings were made simultaneously with videofluoroscopy of a modified bar...


    pub_type: 杂志文章


    authors: Smith D,Hamlet S,Jones L

    更新日期:1990-01-01 00:00:00

  • Unusual Cause of Dysphagia in a Post-Stroke Patient.

    abstract::Vallecular cysts are formed when the duct of a mucous gland or lingual tonsillar crypt is dilated owing to obstruction from inflammation, irritation, or trauma. Small cysts are usually asymptomatic; however, cyst growth results in dysphagia, odynophagia, and acute airway complications. As complete transoral laser exci...


    pub_type: 杂志文章


    authors: Kwon SH,Seo HG

    更新日期:2017-10-01 00:00:00

  • Screening for Dysphagia in Adult Patients with Stroke: Assessing the Accuracy of Informal Detection.

    abstract::Early identification of dysphagia by screening is recommended best practice for patients admitted to hospital with acute stroke. Screening can reduce the risk of pneumonia and promote stroke recovery, yet some institutions do not utilize a formal screening protocol. This study assessed the accuracy of informal dysphag...


    pub_type: 杂志文章


    authors: Sherman V,Flowers H,Kapral MK,Nicholson G,Silver F,Martino R

    更新日期:2018-10-01 00:00:00

  • The Landscape of Videofluoroscopy in the UK: A Web-Based Survey.

    abstract::Videofluoroscopy (VFS) is considered one of the gold-standard assessments of swallowing. Whilst guidelines for the application and conduct of VFS exist, their translation into clinical practice remain challenging. To build a greater understanding on how VFS clinics operate in the UK. A web-based survey was shared with...


    pub_type: 杂志文章


    authors: Benfield JK,Michou E,Everton LF,Mills C,Hamdy S,Bath PM,England TJ

    更新日期:2020-05-16 00:00:00

  • A retrospective analysis of the pharyngeal swallow in patients with a clinical diagnosis of GERD compared with normal controls: a pilot study.

    abstract::In gastroesophageal reflux disease (GERD), there is a reverse flow of gastric contents up through the esophagus and potentially into the pharynx. Some patients who have GERD have reported difficulty in oropharyngeal swallowing. This study was designed to determine whether differences in the pharyngeal swallow exist in...


    pub_type: 杂志文章


    authors: Mendell DA,Logemann JA

    更新日期:2002-07-01 00:00:00

  • Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula.

    abstract::Use of high-flow oxygen via nasal cannula (HFO2-NC) is increasingly common in intensive care unit (ICU) settings. Despite the critical interface between respiration and swallowing, and the high acuity of patients in ICUs, the impact of HFO2-NC on feeding and swallowing is unknown. The present prospective, single-cente...


    pub_type: 杂志文章


    authors: Leder SB,Siner JM,Bizzarro MJ,McGinley BM,Lefton-Greif MA

    更新日期:2016-04-01 00:00:00

  • Combined neuromuscular electrical stimulation (NMES) with fiberoptic endoscopic evaluation of swallowing (FEES) and traditional swallowing rehabilitation in the treatment of stroke-related dysphagia.

    abstract::Dysphagia is common after stroke. Neuromuscular electrical stimulation (NMES) and fiberoptic endoscopic evaluation of swallowing (FEES) for the treatment of dysphagia have gained in popularity, but the combined application of these promising modalities has rarely been studied. We aimed to evaluate whether combined NME...


    pub_type: 临床试验,杂志文章


    authors: Sun SF,Hsu CW,Lin HS,Sun HP,Chang PH,Hsieh WL,Wang JL

    更新日期:2013-12-01 00:00:00

  • Conservative management of a large postlaryngectomy neopharyngeal diverticulum.

    abstract::Dysphagia is common following total laryngectomy. Postlaryngectomy neopharyngeal diverticulae are known to cause postlaryngectomy dysphagia but are more frequently asymptomatic. We report a case presenting with late-onset postlaryngectomy dysphagia and a suprastomal swelling secondary to such a diverticulum. The patie...


    pub_type: 杂志文章


    authors: Montague ML,Davis BC,Riad M

    更新日期:2004-10-01 00:00:00

  • Reliable lip force measurement in healthy controls and in patients with stroke: a methodologic study.

    abstract::A prefabricated oral screen has shown promising results as a muscle self-training device to improve the lip function of stroke patients affected by oropharyngeal dysphagia. However, a technique for the measurement of lip muscle force, whether in healthy individuals or in stroke patients, is lacking. The present study ...


    pub_type: 杂志文章


    authors: Hägg M,Olgarsson M,Anniko M

    更新日期:2008-09-01 00:00:00

  • Confirmation of no causal relationship between tracheotomy and aspiration status: a direct replication study.

    abstract::Debate continues regarding an association between tracheotomy and aspiration status. The aim of this research was to perform a direct replication study to investigate further the causal relationship, if any, between tracheotomy and aspiration. Twenty-five consecutive adult hospitalized patients participated. Inclusion...


    pub_type: 杂志文章


    authors: Leder SB,Ross DA

    更新日期:2010-03-01 00:00:00

  • Chin tuck for prevention of aspiration: effectiveness and appropriate posture.

    abstract::Chin tuck has been has been widely used to prevent aspiration in the patients with dysphagia. This study was performed to investigate the effectiveness and the degree of optimal neck flexion of chin tuck. Ninety-seven patients who showed aspiration in the videofluoroscopic swallow study (VFSS). Participants were group...


    pub_type: 杂志文章


    authors: Ra JY,Hyun JK,Ko KR,Lee SJ

    更新日期:2014-10-01 00:00:00

  • Multiple swallows and piecemeal deglutition; observations from normal adults and patients with head and neck cancer.

    abstract::The incidence of multiple swallows for liquid and paste, and the time delay between multiple swallows, was determined from videofluoroscopic records of modified barium swallow tests. In a comparison of liquid and paste, the overall incidence of multiple swallows did not differ, for either patients with head and neck c...


    pub_type: 杂志文章


    authors: Dziadziola J,Hamlet S,Michou G,Jones L

    更新日期:1992-01-01 00:00:00

  • Economic Analysis of a Three-Arm RCT Exploring the Delivery of Intensive, Prophylactic Swallowing Therapy to Patients with Head and Neck Cancer During (Chemo)Radiotherapy.

    abstract::Research advocates for the use of intensive, prophylactic swallowing therapy to help reduce the severity of dysphagia in patients receiving (chemo)radiotherapy ([C]RT) for head/neck cancer (HNC). Unfortunately, the intensity of this therapy, coupled with growing patient numbers and limited clinical resources, provides...


    pub_type: 杂志文章,随机对照试验


    authors: Wall LR,Kularatna S,Ward EC,Cartmill B,Hill AJ,Isenring E,Byrnes J,Porceddu SV

    更新日期:2019-10-01 00:00:00

  • Three-dimensional muscular architecture of the human tongue determined in vivo with diffusion tensor magnetic resonance imaging.

    abstract::The myoarchitecture of the tongue is believed to consist of a complex network of interwoven fibers, which function together to produce a near limitless array of functional deformations. These deformations contribute mechanically to speech production and to oral cavity food handling during swallowing. We have previousl...


    pub_type: 杂志文章


    authors: Gilbert RJ,Napadow VJ

    更新日期:2005-01-01 00:00:00

  • Moving Forward with Dysphagia Care: Implementing Strategies during the COVID-19 Pandemic and Beyond.

    abstract::Growing numbers of SARS-CoV-2 cases coupled with limited understanding of transmissibility and virulence, have challenged the current workflow and clinical care pathways for the dysphagia provider. At the same time, the need for non-COVID-19-related dysphagia care persists. Increased awareness of asymptomatic virus ca...


    pub_type: 杂志文章,评审


    authors: Fritz MA,Howell RJ,Brodsky MB,Suiter DM,Dhar SI,Rameau A,Richard T,Skelley M,Ashford JR,O'Rourke AK,Kuhn MA

    更新日期:2020-06-09 00:00:00

  • Correlates of Early Pharyngeal High-Resolution Manometry Adoption in Expert Speech-Language Pathologists.

    abstract::Pharyngeal high-resolution manometry (HRM) is at a point of entry into speech-language pathologist (SLP) clinical practice. However, the demographic characteristics of SLPs who are early adopters of HRM are unclear; perspectives of early adopters may shape how the technology is received by the field at large. We hypot...


    pub_type: 杂志文章


    authors: Jones CA,Forgues AL,Rogus-Pulia NM,Orne J,Macdonald CL,Connor NP,McCulloch TM

    更新日期:2019-06-01 00:00:00