Survival of non-Western first generations immigrants with stomach cancer in North East Netherlands.


BACKGROUND:Isolated groups, such as first generation non-Western immigrants, are at risk for suboptimal utilisation of the health care system resulting in a worse outcome. METHODS:From 1989 to 2007, all patients with stomach cancer were selected from the Comprehensive Cancer Centre North-East cancer registry. Associations between country of birth and patient, tumour and treatment characteristics were determined using χ(2) analysis. Relative survival analysis was used to estimate relative excess risk of dying according to country of birth (non-Western vs Western). RESULTS:After adjusting for confounding factors (patient, tumour and treatment related), the risk of dying was lower for first generation non-Western immigrants (relative excess risk 0.55, 95% confidence interval 0.43-0.70) compared with Western patients. CONCLUSION:Although the better survival of first generation non-Western immigrants with stomach cancer remains unexplained, it argues against accessibility problems within the Dutch health care system.


Br J Cancer


Siemerink EJ,van der Aa MA,Siesling S,Hospers GA,Mulder NH




Has Abstract


2011-03-29 00:00:00














  • Childhood acute lymphoblastic leukaemia and indicators of early immune stimulation: the Estelle study (SFCE).

    abstract:BACKGROUND:Factors related to early stimulation of the immune system (breastfeeding, proxies for exposure to infectious agents, normal delivery, and exposure to animals in early life) have been suggested to decrease the risk of childhood acute lymphoblastic leukaemia (ALL). METHODS:The national registry-based case-con...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Ajrouche R,Rudant J,Orsi L,Petit A,Baruchel A,Lambilliotte A,Gambart M,Michel G,Bertrand Y,Ducassou S,Gandemer V,Paillard C,Saumet L,Blin N,Hémon D,Clavel J

    更新日期:2015-03-17 00:00:00

  • Processed meat consumption and risk of cancer: a multisite case-control study in Uruguay.

    abstract:BACKGROUND:The role of processed meat in the aetiology of several cancers was explored in detail. METHODS:In the time period 1996-2004, a multisite case-control study was conducted in Montevideo, Uruguay. The study included 6 060 participants (3 528 cases and 2 532 controls) corresponding to cancers of the oral cavity...

    journal_title:British journal of cancer

    pub_type: 杂志文章,多中心研究


    authors: De Stefani E,Boffetta P,Ronco AL,Deneo-Pellegrini H,Correa P,Acosta G,Mendilaharsu M,Luaces ME,Silva C

    更新日期:2012-10-23 00:00:00

  • The incidence of cancers among second-generation Irish living in England and Wales.

    abstract::The incidence of ovarian, cervical, lung and prostatic cancer was higher in second-generation Irish living in England and Wales than in all other persons in England and Wales. A higher incidence of ovarian cancer was not found in first-generation Irish. Differences in socioeconomic status did not explain these pattern...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Harding S

    更新日期:1998-10-01 00:00:00

  • Presence of activin signal transduction in normal ovarian cells and epithelial ovarian carcinoma.

    abstract::In this study, we have investigated the expression of inhibin subunits and activin receptors (ActRs) in normal and malignant ovarian cells. Each product of the inhibin subunits (alpha, betaa, betab) and activin receptors (ActRs) amplified by reverse transcription polymerase chain reaction were detected as a single ban...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Ito I,Minegishi T,Fukuda J,Shinozaki H,Auersperg N,Leung PC

    更新日期:2000-04-01 00:00:00

  • Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2.

    abstract::Endosialin is a transmembrane glycoprotein selectively expressed in blood vessels and stromal fibroblasts of various human tumours. It has been functionally implicated in angiogenesis, but the factors that control its expression have remained unclear. As insufficient delivery of oxygen is a driving force of angiogenes...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Ohradanova A,Gradin K,Barathova M,Zatovicova M,Holotnakova T,Kopacek J,Parkkila S,Poellinger L,Pastorekova S,Pastorek J

    更新日期:2008-10-21 00:00:00

  • Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21.

    abstract::The cisplatin analogue 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) (DAP) is a DNA-damaging agent that will be entering clinical trials for its potent cytotoxic effects against cisplatin-resistant tumour cells. This cytotoxicity may reside in its ability to selectively activate G1-phase checkpoint r...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: He G,Kuang J,Huang Z,Koomen J,Kobayashi R,Khokhar AR,Siddik ZH

    更新日期:2006-12-04 00:00:00

  • Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells.

    abstract:BACKGROUND:Human polypyrimidine tract binding protein 3 (PTBP3) was first discovered in 1999 and has been well characterised as a differentiation regulator. However, its role in human cancer has rarely been reported. Our previous study revealed increased PTBP3 protein level in gastric cancer tissues. Downregulation of ...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Liang X,Shi H,Yang L,Qiu C,Lin S,Qi Y,Li J,Zhao A,Liu J

    更新日期:2017-03-28 00:00:00

  • High levels of loss at the 17p telomere suggest the close proximity of a tumour suppressor.

    abstract::High levels of loss of distal markers on 17p13.3 in breast cancer suggested the presence within the region of at least one tumour-suppressor gene. Here we describe the derivation of two biallelic polymorphisms from the 17p telomeric yeast artificial chromosome (YAC) TYAC98. Polymerase chain reaction-restriction fragme...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: White GR,Stack M,Santibáñez-Koref M,Liscia DS,Venesio T,Wang JC,Helms C,Donis-Keller H,Betticher DC,Altermatt HJ,Hoban PR,Heighway J

    更新日期:1996-09-01 00:00:00

  • Intake of wholegrain products and risk of colorectal cancers in the Diet, Cancer and Health cohort study.

    abstract:BACKGROUND:Consumption of wholegrain (WG) products may protect against colon and rectal cancer. METHODS:The associations between total and individual WG product consumption and colon and rectal cancer risk were prospectively examined using data on 461 incident cases of colon cancer and 283 incident cases of rectal can...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Egeberg R,Olsen A,Loft S,Christensen J,Johnsen NF,Overvad K,Tjønneland A

    更新日期:2010-08-24 00:00:00

  • Telomerase activity in benign and malignant human thyroid tissues.

    abstract::Telomerase is a specialized ribonucleoprotein polymerase that directs the synthesis of telomerase repeats at chromosome ends. Accumulating evidence has indicated that telomerase is stringently repressed in normal human somatic tissues but reactivated in cancers and immortal cells, suggesting that activation of telomer...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Cheng AJ,Lin JD,Chang T,Wang TC

    更新日期:1998-06-01 00:00:00

  • Differential expression of neurofilament triplet proteins in carcinoid tumours: an immunohistochemical study.

    abstract::Neurofilaments (NFs) are specific intermediate filaments to neural cells. Mammalian NFs are protein triplets composed of three major subunits with respective molecular weights of approximately 70, 150 and 200 kD. Using an immunohistochemical method, 13 carcinoid tumours from different sites were examined for the prese...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Astarloa R,Sánchez-Franco F,Cacicedo L,García-Villanueva M

    更新日期:1991-05-01 00:00:00

  • Human regional tumour lymph nodes: alterations of micro-architecture and lymphocyte subpopulations.

    abstract::Axillary lymph nodes draining mammary carcinoma showed an alteration of both micro-architectue and lymphocyte subpopulations. Lymph nodes with a normal or increased T and/or B lymphocyte compartment (assessed by histology) had a low incidence of nodal tumour spread, whilst hypocellularity of the T- or B-lymphocyte-dep...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Eremin O,Roberts P,Plumb D,Stephens JP

    更新日期:1980-01-01 00:00:00

  • The clinical value of imaging with antibody to human chorionic gonadotrophin in the detection of residual choriocarcinoma.

    abstract::Choriocarcinoma can be imaged by external scintigraphy after intravenous administration of radiolabelled antibody directed against human chorionic gonadotrophin (HCG). The purpose of this study was to investigate whether antibody imaging was sufficiently sensitive and specific to improve the selection of patients for ...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Begent RH,Bagshawe KD,Green AJ,Searle F

    更新日期:1987-06-01 00:00:00

  • Population-based cancer incidence in Sikkim, India: report on ethnic variation.

    abstract:BACKGROUND:A Population-Based Cancer Registry (PBCR) was set up in Sikkim (a state in the North Eastern India) in 2003. We examined incidence rates by ethnic groups from 2003-2008. METHODS:Age-adjusted incidence rates (AARs) per 100,000 person-years were calculated by direct method using the world standard population,...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Verma Y,Pradhan PK,Gurung N,Sapkota SD,Giri P,Sundas P,Bhattarai BN,Nadayil D,Ramnath T,Nandakumar A

    更新日期:2012-02-28 00:00:00

  • Dacarbazine and interferon alpha with or without interleukin 2 in metastatic melanoma: a randomized phase III multicentre trial of the Dermatologic Cooperative Oncology Group (DeCOG).

    abstract::In several phase II-trials encouraging tumour responses rates in advanced metastatic melanoma (stage IV; AJCC-classification) have been reported for the application of biochemotherapy containing interleukin 2. This study was designed to compare the efficacy of therapy with dacarbazine (DTIC) and interferon alpha (IFN-...

    journal_title:British journal of cancer

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Hauschild A,Garbe C,Stolz W,Ellwanger U,Seiter S,Dummer R,Ugurel S,Sebastian G,Nashan D,Linse R,Achtelik W,Mohr P,Kaufmann R,Fey M,Ulrich J,Tilgen W

    更新日期:2001-04-20 00:00:00

  • A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer.

    abstract:BACKGROUND:Only a small proportion of patients respond to anti-VEGF therapy, pressing the need for a reliable biomarker that can identify patients who will benefit. We studied the biological activity of anti-VEGF antibodies in patients' blood during anti-VEGF therapy by using the Ba/F3-VEGFR2 cell line, which is depend...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Wentink MQ,Broxterman HJ,Lam SW,Boven E,Walraven M,Griffioen AW,Pili R,van der Vliet HJ,de Gruijl TD,Verheul HM

    更新日期:2016-10-11 00:00:00

  • An evaluation of liquid-based cytology and human papillomavirus testing within the UK cervical cancer screening programme.

    abstract::The aim of this study is to evaluate different options for introducing liquid-based cytology (LBC) and human papillomavirus (HPV) testing into the UK cervical cancer screening programme. These include options that incorporate HPV testing either as a triage for mild and borderline smear abnormalities or as a primary sc...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Sherlaw-Johnson C,Philips Z

    更新日期:2004-07-05 00:00:00

  • The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.

    abstract::Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that ...

    journal_title:British journal of cancer

    pub_type: 指南,杂志文章


    authors: Leach MO,Brindle KM,Evelhoch JL,Griffiths JR,Horsman MR,Jackson A,Jayson GC,Judson IR,Knopp MV,Maxwell RJ,McIntyre D,Padhani AR,Price P,Rathbone R,Rustin GJ,Tofts PS,Tozer GM,Vennart W,Waterton JC,Williams SR,Work

    更新日期:2005-05-09 00:00:00

  • The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia.

    abstract::In the present study we demonstrate that Aza-dC in combination with Amsacrine has major antileukaemic properties in patients who have not already received extensive Ara-C therapy. Eight out of 11 patients in their first relapse of acute leukaemia achieved complete remission. Cross resistance between Ara-C and Aza-dC w...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Richel DJ,Colly LP,Kluin-Nelemans JC,Willemze R

    更新日期:1991-07-01 00:00:00

  • Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer.

    abstract::Forty-two patients with clinical stage IIIA or IIIB breast cancer were treated with neoadjuvant chemotherapy followed by mastectomy and radiotherapy. The median follow-up was 32 months (range 10-72 months) and the median time to progression was 17 months (range 10-30 months). A multivariate analysis showed that a long...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Honkoop AH,van Diest PJ,de Jong JS,Linn SC,Giaccone G,Hoekman K,Wagstaff J,Pinedo HM

    更新日期:1998-02-01 00:00:00

  • Hospitalisation for venous thromboembolism in cancer patients and the general population: a population-based cohort study in Denmark, 1997-2006.

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    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Cronin-Fenton DP,Søndergaard F,Pedersen LA,Fryzek JP,Cetin K,Acquavella J,Baron JA,Sørensen HT

    更新日期:2010-09-28 00:00:00

  • Major depression in outpatients attending a regional cancer centre: screening and unmet treatment needs.

    abstract::A screening programme designed to identify cases of Major Depressive Disorder (MDD) in patients attending a Regional Cancer Centre outpatient department was established. It comprised two stages: (1) The Hospital Anxiety and Depression Scale (HADS) self-rating questionnaire administered by a touch-screen computer; (2) ...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Sharpe M,Strong V,Allen K,Rush R,Postma K,Tulloh A,Maguire P,House A,Ramirez A,Cull A

    更新日期:2004-01-26 00:00:00

  • The relationship between circulating concentrations of C-reactive protein, inflammatory cytokines and cytokine receptors in patients with non-small-cell lung cancer.

    abstract::The relationship between circulating C-reactive protein concentrations and potential cytokine and receptor mediators (interleukin-6, leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), soluble IL-6 receptor, soluble gp130, soluble TNF receptor, interleukin-1 receptor antagonist and interleukin-8 (IL...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: McKeown DJ,Brown DJ,Kelly A,Wallace AM,McMillan DC

    更新日期:2004-12-13 00:00:00

  • Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology.

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    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Brenner H,Hoffmeister M,Haug U

    更新日期:2008-08-05 00:00:00

  • The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types.

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    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Forget MA,Turcotte S,Beauseigle D,Godin-Ethier J,Pelletier S,Martin J,Tanguay S,Lapointe R

    更新日期:2007-02-26 00:00:00

  • Effects of varying the interval between courses of methotrexate on its myelotoxic and anti-leukaemic activities.

    abstract::The toxicity produced by two courses of methotrexate separated by different intervals has been studied in matched groups of rats. The maximum degree of neutropenia reached when courses were separated by 8 days or more was no greater than that seen after a single course of methotrexate. However, when courses of neutrop...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Harding B,Culvenor J,MacLennan IC

    更新日期:1977-01-01 00:00:00

  • A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer.

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    journal_title:British journal of cancer

    pub_type: 杂志文章,多中心研究


    authors: Ko AH,Tempero MA,Shan YS,Su WC,Lin YL,Dito E,Ong A,Wang YW,Yeh CG,Chen LT

    更新日期:2013-08-20 00:00:00

  • Do multiple oestrogen receptor assays give significant additional information for the management of breast cancer?

    abstract::In 101 breast cancer patients, measurement of oestrogen receptor status in multiple biopsies across a tumour reveals a highly significant difference in the proportion of patients remaining either disease-free (P less than 0.04) or alive (P less than 0.005), when those with uniformly receptor positive (++) primary tumo...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Castagnetta L,Traina A,Di Carlo A,Carruba G,Lo Casto M,Mesiti M,Leake R

    更新日期:1989-04-01 00:00:00

  • The current treatment landscape in the UK for stage III NSCLC.

    abstract::For stage III non-small cell lung cancer (NSCLC), approximately a third of patients survive up to 5 years, with decreasing 5-year survival rates for stage IIIB and stage IIIC disease. Although curable, stage III NSCLC encompasses a diverse range of disease presentation, with an equally complex range of multi-modal tre...

    journal_title:British journal of cancer

    pub_type: 杂志文章,评审


    authors: Evison M,AstraZeneca UK Limited.

    更新日期:2020-12-01 00:00:00

  • Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis.

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    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Hamada J,Cavanaugh PG,Lotan O,Nicolson GL

    更新日期:1992-08-01 00:00:00