Deep brain stimulation and frameless stereotactic radiosurgery in the treatment of bilateral parkinsonian tremor: target selection and case report of two patients.


:Considerable positive experience in functional radiosurgery has been reported since Leksell's first experience in 1951, but the development of frameless radiosurgery was been limited because of the difficulty of identifying invisible functional targets. In this paper we report on two cases of bilateral parkinsonian tremor successfully treated with DBS on one side and with frameless radiosurgery on the contralateral side. We focus on the methodology developed to define the three-dimensional target coordinates for frameless radiosurgery. Two patients suffering from a disabling upper-limb parkinsonian tremor underwent frameless radiosurgical thalamotomy. To accurately identify the treatment target the CT gantry was treated as a stereotactic frame; a rototranslation between the origin of the screen and the origin of the stereotactic atlas allowed us to obtain atlas-registered 3D coordinates of each point on the CT axial brain slices. Both patients achieved complete bilateral tremor control by unilateral radiosurgery and contralateral DBS. We developed a method for determining the 3D coordinates of a known functional target to treat with frameless radiosurgery. Based on the initial experiences, frameless radiosurgery appears to be an alternative treatment for Parkinsonian upper limb tremor in the presence of increased surgical risks for DBS placement.


Acta Neurochir (Wien)


Acta neurochirurgica


Franzini A,Marchetti M,Brait L,Milanesi I,Messina G,Forapani E,Broggi G,Fariselli L




Has Abstract


2011-05-01 00:00:00












  • Evaluation of brain tumour laser surgery.

    abstract::A surgical carbon dioxide laser unit (laser) has been used since 1977 in twenty-five cases of various brain tumours, including ten meningiomas (four sphenoid ridge, two parasagittal, two falx, one olfactory, one posterior fossa), eleven gliomas (seven glioblastoma, four astrocytoma), two metastatic brain tumours, one ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Hara M,Takeuchi K,Okada J,Takizawa T,Matsumoto M

    更新日期:1980-01-01 00:00:00

  • Cyst fluid of glioma does not inhibit the killing action of lymphokine-activated killer (LAK) cells in vitro.

    abstract::In theory, lymphokine-activated killer (LAK) cells offer a potential method to treat cerebral gliomas, especially low-grade gliomas. LAK cells would be administered by repeated injections straight into the cavity of a subtotally removed tumour. However, brain-tumour cyst fluid has been shown to be immunosuppressive in...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Jääskeläinen J,Kalliomäki P,Paetau A,Saksela E,Timonen T

    更新日期:1988-01-01 00:00:00

  • Micro-invasive squamous cell carcinoma arising in a pre-existing intraventricular epidermoid cyst. Case report and literature review.

    abstract::The authors report the case of a 67-year-old woman with primary micro-invasive squamous cell carcinoma located in the lateral ventricle and originating from an epidermoid cyst. Radiological and histological features of the neoplasm are described and the relevant literature is studied briefly. Two consecutive surgical ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Bayindir C,Balak N,Karasu A

    更新日期:1996-01-01 00:00:00

  • An easy and safe method to store and disinfect explanted skull bone.

    abstract::In our department extensive decompression craniectomies became the treatment of choice for patients with massive cerebral oedema following either trauma or acute cerebral infarction. The remarkable survival rates of this neurosurgical technique created the problem of adequate vault defect reconstruction. To evaluate t...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Schültke E,Hampl JA,Jatzwauk L,Krex D,Schackert G

    更新日期:1999-01-01 00:00:00

  • Primary cervical spinal epidural Extra-osseous Ewing's sarcoma.

    abstract::Cases of primary spinal epidural Extra-osseous Ewing's sarcoma (EES) are rarely seen and a good prognosis for EES cannot be expected since a high incidence of local recurrence and metastasis frequently occur. We present a case of cervical spinal epidural EES in a 7-year-old girl with long survival after tumour resecti...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Kogawa M,Asazuma T,Iso K,Koike Y,Domoto H,Aida S,Fujikawa K

    更新日期:2004-09-01 00:00:00

  • Monitoring of facial evoked EMG for hemifacial spasm: a critical analysis of its prognostic value.

    abstract::Microvascular decompression (MVD) has come to stay as an effective way of treating hemifacial spasm. But it remains to be seen how much each of the electrophysiological monitoring techniques (intra-operative) are contributing to its increased efficacy. Their role as indicators for re-exploration or recurrence is to be...

    journal_title:Acta neurochirurgica

    pub_type: 临床试验,杂志文章


    authors: Kiya N,Bannur U,Yamauchi A,Yoshida K,Kato Y,Kanno T

    更新日期:2001-01-01 00:00:00

  • Stereotactic craniotomy and intraoperative lesion localisation using the Brown-Robert-Wells frame. Technical note.

    abstract::A simple technique of stereotactic craniotomy and intraoperative lesion localisation that uses the Brown-Robert-Wells (BRW) stereotactic frame is presented. The method optimises craniotomy placement and facilitates localisation of small intracerebral lesions. Using the system, 16 patients have had resection of intracr...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Sabin HI,Whittle IR

    更新日期:1990-01-01 00:00:00

  • Perimesencephalic and nonperimesencephalic subarachnoid haemorrhages with negative angiograms.

    abstract:BACKGROUND:van Gijn and co-workers identified "Perimesencephalic haemorrhage" (PM) as distinct, benign, non-aneurysmal subarachnoid haemorrhage. However, there is only one retrospective series of this entity outside the Netherlands. PURPOSE:to confirm (or not) the benign nature of perimesencephalic subarachnoid haemor...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Canhão P,Ferro JM,Pinto AN,Melo TP,Campos JG

    更新日期:1995-01-01 00:00:00

  • Complete removal of colloid cyst via CT-guided stereotactic biportal neuroendoscopy.

    abstract::Four patients harbouring a colloid cyst of the 3rd ventricle were operated on endoscopically. With the "classical" monoportal technique, through a precoronal burr hole only partial removal could be achieved in the first case. As the crucial point of the procedure is the safe dissection of the cyst from the thela chori...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Horváth Z,Vetö F,Balás I,Dóczi T

    更新日期:2000-01-01 00:00:00

  • Ependymoma misdiagnosed as tuberculoma, misguided by overemphasis on MR spectroscopy in endemic area.

    abstract::Ependymomas and tuberculomas are common paediatric posterior fossa lesions in developing countries and may be confused with each other due to some overlapping features. The distinction is important as the treatment for each is entirely different. We have described three young children in whom clinical-radiological fea...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Futane S,Salunke P,Sahoo S,Mulinani N,Vyas S

    更新日期:2013-10-01 00:00:00

  • Gamma knife radiosurgical management of petroclival meningiomas results and indications.

    abstract:BACKGROUND:Surgical treatment of petroclival meningiomas remains challenging. In order to refine indications for the use of stereotactic radiosurgery in the treatment of these tumours, we retrospectively evaluated our experience in this field. METHODS:Thirty-two patients harboring a petroclival meningioma were treated...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Roche PH,Pellet W,Fuentes S,Thomassin JM,Régis J

    更新日期:2003-10-01 00:00:00

  • Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury.

    abstract:OBJECTIVE:The purpose of the study was to measure the effects of increased inspired oxygen on patients suffering severe head injury and consequent influences on the correlations between CPP and brain tissue oxygen (PtiO2) and the effects on brain microdialysate glucose and lactate. METHODS:In a prospective, observatio...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Reinert M,Barth A,Rothen HU,Schaller B,Takala J,Seiler RW

    更新日期:2003-05-01 00:00:00

  • How good are the outcomes of instrumented debulking operations for symptomatic spinal metastases and how long do they stand? A subgroup analysis in the global spine tumor study group database.

    abstract:BACKGROUND:The benefits of surgery for symptomatic spinal metastases have been demonstrated, largely based on series of patients undergoing debulking and instrumentation operations. However, as cancer treatments improve and overall survival lengths increase, the incidence of recurrent spinal cord compression after debu...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,多中心研究


    authors: Depreitere B,Ricciardi F,Arts M,Balabaud L,Bunger C,Buchowski JM,Chung CK,Coppes MH,Fehlings MG,Kawahara N,Martin-Benlloch JA,Massicotte EM,Mazel C,Meyer B,Oner FC,Peul W,Quraishi N,Tokuhashi Y,Tomita K,Verlaan JJ,

    更新日期:2020-04-01 00:00:00

  • Giant cell tumor of the lumbar spine with intraperitoneal growth: case report and review of literature.

    abstract::Giant cell tumors of the spine are uncommon. Usually they are benign and solitary, but locally very aggressive. Most of them occur at the sacral spine. There are only 26 reported cases in the literature involving this type of tumor in the lumbar spine, in particular exhibiting an intraperitoneal growth. We present the...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,评审


    authors: Munoz-Bendix C,Cornelius JF,Bostelmann R,Gierga K,Steiger HJ

    更新日期:2013-07-01 00:00:00

  • Clinical features of postoperative cerebral venous infarction.

    abstract::There is a potential risk of sacrificing the cortical vein during neurosurgical operations, particularly in the interhemispheric or subtemporal approach. An impaired cortical vein might cause cerebral venous circulatory disturbances (CVCDs) resulting in venous infarction. In this article, we have reviewed the manageme...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Nakase H,Shin Y,Nakagawa I,Kimura R,Sakaki T

    更新日期:2005-06-01 00:00:00

  • Ectopic choroid plexus associated with trigeminal neuralgia: case report.

    abstract:INTRODUCTION:A 55-year-old man underwent a microvascular decompression procedure for a pharmacoresistant trigeminal neuralgia. Preoperative MRI showed a neurovascular conflict between the Vth nerve root and the superior cerebellar artery. METHODS:Dissection of the intracisternal trigeminal root was undertaken, and a p...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Abeloos L,Massager N

    更新日期:2010-04-01 00:00:00

  • Circulating immune complexes in intracranial neoplasms.

    abstract::The levels of circulating immune complexes (CIC) were assayed in the sera of 109 patients with intracranial space occupying lesions. The CIC levels were significantly increased in all the brain tumours. After treatment, the CIC levels were still significantly increased when compared to the controls but showed no chang...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Manjula S,Aroor AR,Raja A,Rao SN,Rao A

    更新日期:1995-01-01 00:00:00

  • Transsphenoidal surgery for acromegaly: predicting remission with early postoperative growth hormone assays.

    abstract:BACKGROUND:Early detection of residual disease may benefit management strategies in patients undergoing transsphenoidal surgery for acromegaly. This requires establishing objective thresholds for early postoperative growth hormone (GH) assays, and incorporating these parameters into a scale for outcome prediction. MET...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Sarkar S,Jacob KS,Pratheesh R,Chacko AG

    更新日期:2014-07-01 00:00:00

  • An isotope agarose assay for rapid testing of the sensitivity of glioma biopsies to chemotherapeutic drugs and biological response modifiers. Effects of BCNU, vincristine, lymphokines and the recombinant agents interferon alpha 2c, interferon gamma and tu

    abstract::A method based on growth of cells from glioma biopsies in a triple layer agarose system has been used to test the sensitivity of the tumour cells to different chemotherapeutic and immunotherapeutic agents. A special agarose that could be melted at 65 degrees C, enabled registration of proliferation by an easy and prec...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Unsgaard G,Helseth E,Vik R,Dalen A

    更新日期:1988-01-01 00:00:00

  • Near-infrared indocyanine green videoangiography for assessment of carotid endarterectomy.

    abstract:BACKGROUND:Intraoperative fluorescence angiography with indocyanine green (ICG) as a tracer has recently been introduced as a novel technique for neurosurgery. We evaluated the feasibility and efficacy of near-infrared (NIR) indocyanine green (ICG) videoangiography for patients undergoing carotid endarterectomy (CEA). ...

    journal_title:Acta neurochirurgica

    pub_type: 临床试验,杂志文章


    authors: Haga S,Nagata S,Uka A,Akagi Y,Hamada Y,Shono T

    更新日期:2011-08-01 00:00:00

  • Treatment of patients with ruptured aneurysm by neurosurgeons that perform both open surgical and endovascular techniques is safe and effective: results of a single centre in Europe.

    abstract::In Europe only few neurosurgeons are trained in both open surgical clipping as well as in endovascular techniques for treatment of intracranial aneurysms. To investigate the safety and efficacy of performing both techniques we, two dual trained neurosurgeons, analyzed our results in repairing ruptured intracranial ane...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: de Vries J,Boogaarts HD

    更新日期:2014-07-01 00:00:00

  • Recovery of the electrocorticogram after incomplete and complete ischaemia of the brain.

    abstract::Incomplete cerebral ischaemia of 10 to 60 minutes duration was performed by reducing the perfusion pressure of completely isolated canine heads at brain temperatures of 37 and 32 degrees C. Complete cerebral ischaemia of the same duration was performed by complete stopping of the perfusion. The latency of recovery of ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Hirsch H

    更新日期:1982-01-01 00:00:00

  • Meningiomas from a developmental perspective: exploring the crossroads between meningeal embryology and tumorigenesis.

    abstract::Meningiomas are tumors arising from the meninges and represent the most frequent central nervous system tumors in adults. Recent large-scale genetic studies and preclinical meningioma mouse modelling led to a better comprehension of meningioma development and suggested evidences of close relationships between meningea...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,评审


    authors: Boetto J,Peyre M,Kalamarides M

    更新日期:2021-01-01 00:00:00

  • The collateral fallout of COVID19 lockdown on patients with head injury from north-west India.

    abstract:BACKGROUND:The COVID19 lockdown has altered the dynamics of living. Its collateral fallout on head injury care has not been studied in detail, especially from low- and middle-income countries, possibly overwhelmed more than developed nations. Here, we analyze the effects of COVID19 restrictions on head injury patients ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Karthigeyan M,Dhandapani S,Salunke P,Sahoo SK,Kataria MS,Singh A,Gendle C,Panchal C,Chhabra R,Jain K,Gupta SK

    更新日期:2021-01-21 00:00:00

  • Transcavernous sinus pituitary gland transposition: how I do it.

    abstract:BACKGROUND:Pituitary transposition preserving gland function is possible when approaching superior clival region tumors. Clinical experience along with detailed anatomical knowledge makes this technique safe and effective. METHOD:We present a step by step description of our technique based on the most recent anatomica...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Cárdenas Ruiz-Valdepeñas E,Kaen A,Tirado Caballero J

    更新日期:2019-10-01 00:00:00

  • Aneurysms of the vertebro-basilar junction area: preliminary experience in endovascular and surgical management.

    abstract::Aneurysms of the vertebro-basilar junction area have been considered the most difficult to be surgically treated because of their deep location, the proximity of the brain stem and the cranial nerves. However, at present, new endovascular techniques and new transbasal surgical approaches offer valuable management stra...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Collice M,Arena O,D'Aliberti G,Todaro C,Branca V,Boccardi E,Versari PP,Bizzozero L,Talamonti G

    更新日期:1997-01-01 00:00:00

  • The management of pituitary tumours and post-operative visual deterioration.

    abstract::The indications and results of transsphenoidal surgery for pituitary adenomas are analysed. The advantages and disadvantages of Bromocriptine and radiotherapy are considered. Transsphenoidal surgery does not damage pre-existing pituitary function. It produces excellent results in micro and mesoadenomas, curing about 7...

    journal_title:Acta neurochirurgica

    pub_type: 传,历史文章,杂志文章


    authors: Adams CB

    更新日期:1988-01-01 00:00:00

  • Pitfalls in the diagnosis of arrested hydrocephalus.

    abstract::Arrested hydrocephalus probably results from improvement of CSF circulation during growth. Although a generally accepted condition, its mode of onset, its presence in a given patient, and time required to establish the absence of progressive hydrocephalus have not been defined. Five patients are presented with ostensi...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: James HE,Schut L

    更新日期:1978-01-01 00:00:00

  • Giant intracranial aneurysm of the anterior communicating artery treated by direct surgery using A3-A3 side-to-side anastomosis and A3-RA graft-STA anastomosis.

    abstract::We describe a giant aneurysm of the anterior communicating artery (ACoA) which was treated with a STA-RA graft-A3 bonnet bypass and A3-A3 side-to-side anastomosis. A giant and partially thrombosed ACoA aneurysm was partially coated 3 years before his current presentation, its gradual increase producing visual field di...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Kim K,Mizunari T,Mizutani N,Kobayashi S,Takizawa K,Kamiyama H,Murai Y,Teramoto A

    更新日期:2006-03-01 00:00:00

  • Comparison of somatosensory evoked responses from root and cord recorded by skin and epidural electrodes using stimulation of the median nerve in cervical radiculopathy and radiculomyelopathy.

    abstract::Somatosensory evoked potentials (SEPs) were recorded by stimulating the median nerve at the wrist from the skin and epidural space of the 7th cervical spine in patients suffering from cervical radiculopathy or radiculomyelopathy. The patients were divided into four subgroups according to the severity of the disease. S...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Heiskari M,Tolonen U,Nyström SH

    更新日期:1986-01-01 00:00:00