Abstract:
:Considerable positive experience in functional radiosurgery has been reported since Leksell's first experience in 1951, but the development of frameless radiosurgery was been limited because of the difficulty of identifying invisible functional targets. In this paper we report on two cases of bilateral parkinsonian tremor successfully treated with DBS on one side and with frameless radiosurgery on the contralateral side. We focus on the methodology developed to define the three-dimensional target coordinates for frameless radiosurgery. Two patients suffering from a disabling upper-limb parkinsonian tremor underwent frameless radiosurgical thalamotomy. To accurately identify the treatment target the CT gantry was treated as a stereotactic frame; a rototranslation between the origin of the screen and the origin of the stereotactic atlas allowed us to obtain atlas-registered 3D coordinates of each point on the CT axial brain slices. Both patients achieved complete bilateral tremor control by unilateral radiosurgery and contralateral DBS. We developed a method for determining the 3D coordinates of a known functional target to treat with frameless radiosurgery. Based on the initial experiences, frameless radiosurgery appears to be an alternative treatment for Parkinsonian upper limb tremor in the presence of increased surgical risks for DBS placement.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Franzini A,Marchetti M,Brait L,Milanesi I,Messina G,Forapani E,Broggi G,Fariselli Ldoi
10.1007/s00701-011-0962-0subject
Has Abstractpub_date
2011-05-01 00:00:00pages
1069-75issue
5eissn
0001-6268issn
0942-0940journal_volume
153pub_type
杂志文章abstract:OBJECTIVES:Ballistic injuries to peripheral nerves pose special challenges in terms of indications, timing and type of surgical intervention. The aim of the present work was to analyze our experience in the surgical treatment of peripheral nerve ballistic injuries with respect to the mechanism of injury (gunshot versus...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2139-0
更新日期:2014-08-01 00:00:00
abstract::Though the brain bulk has been considered to be constant in several pressure homeostasis studies, the central nervous tissue may be responsible for the accommodation of extracerebral masses exceeding the volume regulation capacity of the cerebral blood and cerebrospinal fluid. Volume buffering of the nervous tissue ma...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/BF01405174
更新日期:1993-01-01 00:00:00
abstract::Between 1984 and 1991 86 patients with single cerebral metastases underwent linear accelerator radiosurgery using the atraumatic and reproducible Greitz-Bergström head-fixation device. Routine one-month follow-up documented disappearance of the tumour in 16 patients, with resolution of the oedema and ventricular shift...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01809265
更新日期:1993-01-01 00:00:00
abstract::The case report here deals with an intracavernous arterial aneurysm spontaneously developing into a carotid-cavernous fistula. The etiopathology of these fistulas is discussed. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406042
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:Complete yet safe resection close to motor areas in medically intractable epilepsy requires functional information. New deficit may occur despite preservation of motor cortex, e.g., through vascular compromise. Here, we explore for the first time the feasibility, safety, and the clinical value of continuous mot...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0675-9
更新日期:2010-08-01 00:00:00
abstract::One hundred and fifty patients with trigeminal neuralgia were treated by percutaneous compression of the Gasserian ganglion (PCGG) during the last 8 years. The technique is the one described by Mullan with the balloon inflated during 6 minutes with 0,7 cc of contrast medium. Over a follow-up period ranging from 6 mont...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411438
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Corrective craniosynostosis surgery is often associated with a large amount of blood loss and metabolic disturbances. In the present study, we investigated the severity, duration of metabolic disturbances, and causal risk factors in infants. METHODS:A retrospective analysis was performed of 36 infants who u...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2441-5
更新日期:2015-07-01 00:00:00
abstract::Results of measurements in vivo of intracranial pressure obtained with a new telemetric epidural pressure transducer are described. The relations of epidural pressure to ventricular fluid pressure are studied in acute experiments and found to be linear, but variable. The functioning of 18 transducers was studied over ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01769143
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:Surgical intervention for unruptured intracranial aneurysms (IAs) carries inherent health risks. The analysis of "patient-specific" IA geometric and computational fluid dynamics (CFD) simulated wall shear stress (WSS) data has been investigated to differentiate IAs at high and low risk of rupture to help cli...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04616-y
更新日期:2020-10-17 00:00:00
abstract::The authors describe a case of a post-traumatic subdural haematoma with an unusual evolution in two phases, one slow, the other very rapid. The rapidity of the evolution was caused by the rupture of a cortical dural artery, shown angiographically. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401797
更新日期:1979-01-01 00:00:00
abstract::A treatment protocol for a controlled open study in patients with subarachnoid haemorrhage (SAH) from cerebral aneurysms is presented, applying acute surgery and pharmacological prevention of symptomatic vasospasm: In patients clinically graded I-III (Hunt and Hess), operation is performed within 48 to 72 hours. After...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401814
更新日期:1983-01-01 00:00:00
abstract:OBJECT:The aim of this study was to document the possible role of Gamma Knife radiosurgery, suitable for the treatment of deep and well limited tumors, in the management of pineal parenchymal tumors (PPT). POPULATION AND METHODS:We reviewed retrospectively a series of 13 patients with PPT treated by Gamma Knife radios...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0626-z
更新日期:2006-01-01 00:00:00
abstract::The unusual presentation of Gorham's disease of skull base and cervical spine in a two-year-old female child with radiological signs mimicking those of raised intracranial pressure is discussed. The differential diagnosis consists of skull base tumours, meningitis, osteomyelitis of the base of skull, congenital hydroc...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0806-x
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:An intracranial in situ side to side posterior circulation procedure is performed infrequently. The scope of treatment modalities of vertebral artery-PICA aneurysms and vertebral dissections is limited due to the lack of many representations of this procedure's technical nuances. METHODS:To demonstrate the ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1874-y
更新日期:2013-11-01 00:00:00
abstract::50 patients with acromegaly and carpal tunnel syndrome have been examined electrophysiologically before and after transnasal operation of the pituitary adenoma. 32 of the 50 patients (64%) had symptoms of carpal tunnel syndrome. 13 of them had neurological deficits. 28 of the examined patients had pathological neurogr...
journal_title:Acta neurochirurgica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01420508
更新日期:1986-01-01 00:00:00
abstract::Clinical presentation, diagnosis, surgical technique and results of 25 cases of intramedullary tumours in patients under 16 years of age are analyzed. Pre-operative spinal deformity was present in 9 patients. Surgery was performed in all. After multilaminectomy with preservation of the intervertebral joints, total rem...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02001471
更新日期:1993-01-01 00:00:00
abstract::Regional cerebral blood flow, recorded by the 133Xenon inhalation method, was measured preoperatively and over a five years postoperative period in six patients with completed stroke and stabilized neurological deficits, who had undergone omental transposition for revascularization of the ischaemic brain. Comparisons ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01809458
更新日期:1990-01-01 00:00:00
abstract::The authors report their experience with CT scanning ina series of 4 cases of subdural empyema, over a period of 10 months; all the patients were male, aged 16 to 25 years. A review of the literature shows that this disease, in spite of the large variety and efficacy of the available antibiotics, is marked by a signif...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01740084
更新日期:1982-01-01 00:00:00
abstract::The authors report two unusual cases in which a malignant astrocytoma developed at the site of the excision of an earlier medulloblastoma. While the precise etiology of these astrocytic tumours was unproven, theories of the origins of the second tumours, particularly in relation to the basic nature of medulloblastomas...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010170048
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The study was conducted to determine the causative factors in the postoperative recurrence (PR) of chronic subdural haematomas (CSDHs) and to evaluate the efficacy of surgery in adults enrolled in this trial. METHODS:99 patients with 121 CSDHs, who were operated on between January 1999 and December 2001, we...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0616-1
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:The aim of this study is to describe microsurgical anatomy and to quantitatively analyze exposure using the posterior subtemporal keyhole (PSK) approach combined with the transchoroidal keyhole (TCK) approach to the ambient cistern. METHODS:We determined the proper location of craniotomy of such combined keyho...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0800-9
更新日期:2010-11-01 00:00:00
abstract::General aspects of glioblastomas are considered such as preoperative diagnosis, stereotactic punctures for tissue samples, location and tumour size, interference with CSF circulation. The operative risk and different approaches to treatment are discussed, and the results are compared. The described combined treatment ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406638
更新日期:1978-01-01 00:00:00
abstract::Rats were inoculated with staphylococcus aureus to produce cerebral abscesses and treated with either antibiotic or dexamethasone and with antibiotic plus dexamethasone at sequential stages of abscess formation. Antibiotic alone shortened the cerebritis stage, accelerated the encapsulation and affected the bacterial c...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01456174
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The axolemmal distribution and density of voltage-gated sodium channels largely determines the electrical excitability of sprouting neurites. Recent evidence suggests that accumulation of sodium channels at injured axonal tips may be responsible for ectopic axonal hyperexcitability and the resulting abnormal...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-002-0970-1
更新日期:2002-08-01 00:00:00
abstract::The clinical, radiological and surgical findings of 56 patients with congenital malformations of the craniovertebral junction who underwent surgical intervention in the Department of Neurosurgery, Hacettepe University Medical School were reviewed. The anomalies were classified according to their embryonic origin. Fort...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808763
更新日期:1994-01-01 00:00:00
abstract::The feline infusion model of brain edema was used to evaluate the pathophysiological effects of 0.6 ml infusions of autologous serum protein (66%), human serum protein (66%), human glioma cyst fluid and a tissue culture medium (TCM) on the structure and function of the forebrain white matter. These infusions increased...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112037
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:van Gijn and co-workers identified "Perimesencephalic haemorrhage" (PM) as distinct, benign, non-aneurysmal subarachnoid haemorrhage. However, there is only one retrospective series of this entity outside the Netherlands. PURPOSE:to confirm (or not) the benign nature of perimesencephalic subarachnoid haemor...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01404842
更新日期:1995-01-01 00:00:00
abstract::The mechanisms by which mexiletine exerts its effects in increasing myocardial circulation, and smooth muscle perfusion and alleviating diabetic neuropathic pain have been widely discussed. The purpose of this study was to examine the protective effect of this compound in ischemia/reperfusion-induced cerebral injury f...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010200023
更新日期:2002-02-01 00:00:00
abstract::The ventriculographic findings of a severe ascending transtentorial herniation that occurred after shunting in an infant with a posterior fossa tumour are described. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405337
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Age is an important factor in determining prognosis following severe head injury (SHI), although mortality in patients > or =65 years is poorly reported. The aim of this study was to document mortality in patients with SHI > or =65 years. METHODS:A retrospective analysis of prospectively collected data from...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0666-x
更新日期:2010-08-01 00:00:00