Intertrial coherence and causal interaction among independent EEG components.


:Over the past few years there has been an increased interest in studying the underlying neural mechanism of attention and cognitive brain activity. This paper aims towards identifying and analyzing distinct responses in an auditory working memory paradigm, as independent components with variable latency, frequency and phase characteristics. The event-related nature of components (either phase or non-phase-locked) over multiple trials is thoroughly examined through intertrial coherence measures. Furthermore, the functional coupling of independent components is investigated through the concept of partial directed coherence depicted as a directed graph. Using these tools, the paper compares issues of activation, connectivity and directionality in the synchronization maps of two populations, of control and Alzheimer's subjects. The results on real data from an oddball experiment verify and further enhance the findings of previous studies and illustrate the potential of the proposed analysis framework.


J Neurosci Methods


Zervakis M,Michalopoulos K,Iordanidou V,Sakkalis V




Has Abstract


2011-04-30 00:00:00














  • Pressure injections of fluid in the nanoliter range via micropipettes.

    abstract::The relationship between pressure, ejection duration and volume ejected was experimentally determined in vitro for micropipettes with different external tip diameters. The relationship between ejection duration and ejected volume is linear in the steady state (i.e. with ejection durations of 1 s or longer) and at suff...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: van Dongen PA

    更新日期:1984-04-01 00:00:00

  • Comparison of extraction methods for peptidomics analysis of mouse brain tissue.

    abstract::The peptidome encompasses all the peptides present in a particular cell, tissue or organism at a particular point in time. Neuropeptidomics studies the peptidome of the nervous system and will become increasingly important in neuroscience research. Novel peptides can be discovered and, when applied to disease models, ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Van Dijck A,Hayakawa E,Landuyt B,Baggerman G,Van Dam D,Luyten W,Schoofs L,De Deyn PP

    更新日期:2011-04-30 00:00:00

  • Multi-lipofection efficiently transfected genes into astrocytes in primary culture.

    abstract::This study demonstrated that liposome-mediated transfection - lipofection - is suitable for delivering genes into astrocytes. By repeatedly lipofecting the same astrocyte cultures, a process we call multi-lipofection, the transfection efficiency of the beta-galactosidase (beta-gal) gene was improved from 2.6+/-0.6 to ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Wu BY,Liu RY,So KL,Yu AC

    更新日期:2000-10-30 00:00:00

  • Component analysis of the responses of sensory neurons to combined sinusoidal and triangular stimulation.

    abstract::A method for quantitative estimation of sensory neuron sensitivity to small sinusoidal stimuli in the presence of sizable background drift (in the stimulus or response) was developed. The performance of the method was tested by analyzing the responses of 17 muscle spindle primary (Ia) afferent neurons to concomitant s...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Hulliger M,Baumann TK

    更新日期:1994-08-01 00:00:00

  • Automated analysis of secretory vesicle distribution at the ultrastructural level.

    abstract::Neuroendocrine cells like chromaffin cells and PC-12 cells are established models for transport, docking and secretion of secretory vesicles. In micrographs, these vesicles are recognized by their electron dense core. The analysis of secretory vesicle distribution is usually performed manually, which is labour-intensi...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: van Weering JR,Wijntjes R,de Wit H,Wortel J,Cornelisse LN,Veldkamp WJ,Verhage M

    更新日期:2008-08-15 00:00:00

  • Determination of in vivo amino acid neurotransmitters by high-performance liquid chromatography with o-phthalaldehyde-sulphite derivatisation.

    abstract::The measurement of amino acid neurotransmitters by high-performance liquid chromatography (HPLC) has emerged as a reliable and sensitive method. This paper describes a method which employs electrochemical (EC) detection of amino acid derivatives formed by a reaction with o-phthalaldehyde (OPA) in the presence of sulph...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Rowley HL,Martin KF,Marsden CA

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  • A novel computational approach for automatic dendrite spines detection in two-photon laser scan microscopy.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Cheng J,Zhou X,Miller E,Witt RM,Zhu J,Sabatini BL,Wong ST

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  • A new high resolution radioimager for the quantitative analysis of radiolabelled molecules in tissue section.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


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    更新日期:1998-12-31 00:00:00

  • A simple computer-based method for performing and analyzing intracranial self-stimulation experiments in rats.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Kling-Petersen T,Svensson K

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  • Susceptibility artifact correction for sub-millimeter fMRI using inverse phase encoding registration and T1 weighted regularization.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Duong STM,Phung SL,Bouzerdoum A,Boyd Taylor HG,Puckett AM,Schira MM

    更新日期:2020-04-15 00:00:00

  • A low-noise flexible integrated system for recording and analysis of multiple electrical signals during sleep-wake states in rats.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Shaw FZ,Lai CJ,Chiu TH

    更新日期:2002-07-30 00:00:00

  • A novel AX+/BX- paradigm to assess fear learning and safety-signal processing with repeated-measure designs.

    abstract::One of the core symptoms of anxiety disorders, such as post-traumatic stress disorder, is the failure to overcome feelings of danger despite being in a safe environment. This deficit likely stems from an inability to fully process safety signals, which are cues in the environment that enable healthy individuals to ove...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Zuure MB,Cohen MX

    更新日期:2020-12-25 00:00:00

  • A bio-friendly and economical technique for chronic implantation of multiple microelectrode arrays.

    abstract::Many neurophysiological experiments on rodents and non-human primates involve the implantation of more than one multi-electrode array to record from many regions of the brain. So called 'floating' microelectrode arrays are implanted in cortical regions of interest and are coupled via a flexible cable to their connecto...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Chhatbar PY,von Kraus LM,Semework M,Francis JT

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    abstract:BACKGROUND:Single unit recording in behaving nonhuman primates is widely used to study the primate central nervous system. However, certain questions cannot be addressed without recording large numbers of neurons simultaneously. Multiple 96-electrode probes can be implanted at one time, but certain problems must be ove...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Mitz AR,Bartolo R,Saunders RC,Browning PG,Talbot T,Averbeck BB

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  • A perfused in vitro preparation of hypothalamus for electrophysiological studies on neurosecretory neurons.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


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  • Intrapulpal nerve stimulation in the rat.

    abstract::Electrical stimulation of the rat incisor pulp has been frequently used as a method to study the mechanisms of pain. However, several of the techniques used to stimulate nociceptive nerves in these teeth also tend to excite non-nociceptive nerves in adjacent tissues. This report deals with the development and verifica...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Myslinski N,Matthews B

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  • Voltage-sensitive dye recording using retrogradely transported dye in the chicken spinal cord: staining and signal characteristics.

    abstract::We describe a novel method for retrogradely labeling specific neuronal populations using voltage-sensitive dyes. Styryl dyes were injected into the ventral roots of the isolated embryonic chick spinal cord. After waiting several hours, the dye labeled motoneurons and autonomic preganglionic neurons. Neuronal cell bodi...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Wenner P,Tsau Y,Cohen LB,O'Donovan MJ,Dan Y

    更新日期:1996-12-28 00:00:00

  • Comparison of the efficacy of four viral vectors for transducing hypothalamic magnocellular neurosecretory neurons in the rat supraoptic nucleus.

    abstract::Since transgenes were first cloned into recombinant adenoviruses almost 30 years ago, a variety of viral vectors have become important tools in genetic research. Viruses adeptly transport genetic material into eukaryotic cells, and replacing all or part of the viral genome with genes of interest or silencing sequences...

    journal_title:Journal of neuroscience methods

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    authors: Doherty FC,Schaack JB,Sladek CD

    更新日期:2011-04-30 00:00:00

  • A rapid fluorescent method to quantify neuronal loss after experimental intracerebral hemorrhage.

    abstract::Neuronal loss in tissue surrounding an intracerebral hemorrhage (ICH) is usually quantified by labor-intensive histological methods that are subject to bias. Fluorescent protein expression has been successfully used as a marker of cell viability in vitro and in retinal studies in vivo, but not in any ICH model to date...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Chen-Roetling J,Lu X,Regan KA,Regan RF

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  • Inter-rater and intra-rater reliability of cerebral blood flow measures obtained using the Brain Acoustic Monitor.

    abstract:BACKGROUND:Current assessment of sport-related concussion involves a multifaceted approach including neurocognitive testing, symptom report, and balance assessment. Lacking from this paradigm is a truly objective measure of the physiological changes associated with concussion. NEW METHOD:A device called the Brain Acou...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Acocello S,Broshek DK,Saliba S

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    abstract::There are 3 known forms of synaptic plasticity at CNS synapses: long-term potentiation (LTP) mediated by NMDA receptor activation, LTP mediated by voltage-dependent calcium channel (VDCC) activation, and long-term depression (LTD) mediated by the NMDA receptor. All 3 forms of synaptic plasticity can be observed in hip...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Teyler TJ,Cavus I,Coussens C

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  • Animal models for studying transport across the blood-brain barrier.

    abstract::There are many reasons for wishing to determine the rate of uptake of a drug from blood into brain parenchyma. However, when faced with doing so for the first time, choosing a method can be a formidable task. There are at least 7 methods from which to choose: indicator dilution, brain uptake index, microdialysis, exte...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章,评审


    authors: Bonate PL

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    abstract::A common approach to test the time-response of carbon fibre microelectrodes entails the use of a flow injection system which allows delivery of a bolus of test compound in the flow stream to a detector electrode. The introduced bolus is distorted from its original form by convective and dispersive forces during the pe...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Yavich L

    更新日期:1998-10-01 00:00:00

  • Neurofilament-histomorphometry comparison in the evaluation of unmyelinated axon regeneration following peripheral nerve injury: An alternative to electron microscopy.

    abstract:BACKGROUND:Currently, assessment of unmyelinated axon regeneration is limited to electron microscopy (EM), which is expensive, time consuming and not universally available. This study presents a protocol to estimate the number of unmyelinated axons in a regenerating peripheral nerve without the need for electron micros...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Hendry JM,Alvarez-Veronesi MC,Chiang C,Gordon T,Borschel GH

    更新日期:2019-05-15 00:00:00

  • iELVis: An open source MATLAB toolbox for localizing and visualizing human intracranial electrode data.

    abstract:BACKGROUND:Intracranial electrical recordings (iEEG) and brain stimulation (iEBS) are invaluable human neuroscience methodologies. However, the value of such data is often unrealized as many laboratories lack tools for localizing electrodes relative to anatomy. To remedy this, we have developed a MATLAB toolbox for int...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Groppe DM,Bickel S,Dykstra AR,Wang X,Mégevand P,Mercier MR,Lado FA,Mehta AD,Honey CJ

    更新日期:2017-04-01 00:00:00

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Sharkey KA,Cervero F

    更新日期:1986-04-01 00:00:00

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Ball T,Derix J,Wentlandt J,Wieckhorst B,Speck O,Schulze-Bonhage A,Mutschler I

    更新日期:2009-05-30 00:00:00

  • A dual RF resonator system for high-field functional magnetic resonance imaging of small animals.

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    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Ludwig R,Bodgdanov G,King J,Allard A,Ferris CF

    更新日期:2004-01-30 00:00:00

  • Cleaning MEG artifacts using external cues.

    abstract::Using EEG, ECoG, MEG, and microelectrodes to record brain activity is prone to multiple artifacts. The main power line (mains line), video equipment, mechanical vibrations and activities outside the brain are the most common sources of artifacts. MEG amplitudes are low, and even small artifacts distort recordings. In ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章


    authors: Tal I,Abeles M

    更新日期:2013-07-15 00:00:00