Abstract:
:Over the past few years there has been an increased interest in studying the underlying neural mechanism of attention and cognitive brain activity. This paper aims towards identifying and analyzing distinct responses in an auditory working memory paradigm, as independent components with variable latency, frequency and phase characteristics. The event-related nature of components (either phase or non-phase-locked) over multiple trials is thoroughly examined through intertrial coherence measures. Furthermore, the functional coupling of independent components is investigated through the concept of partial directed coherence depicted as a directed graph. Using these tools, the paper compares issues of activation, connectivity and directionality in the synchronization maps of two populations, of control and Alzheimer's subjects. The results on real data from an oddball experiment verify and further enhance the findings of previous studies and illustrate the potential of the proposed analysis framework.
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Zervakis M,Michalopoulos K,Iordanidou V,Sakkalis Vdoi
10.1016/j.jneumeth.2011.02.001subject
Has Abstractpub_date
2011-04-30 00:00:00pages
302-14issue
2eissn
0165-0270issn
1872-678Xpii
S0165-0270(11)00076-8journal_volume
197pub_type
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