Abstract:
:In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effectiveness. To set ceiling prices, IQWiG uses the following decision rule: the incremental cost-effectiveness ratio (ICER) of a new drug compared with the next effective intervention should not be higher than that of the next effective intervention compared with its comparator. The purpose of this article is to analyse ethical implications of IQWiG's rule and compare them with those of two alternative decision rules, one that is based on an absolute cost-effectiveness threshold and one that falls in between. To this end, constrained optimization problems are defined that yield each decision rule. This article shows that IQWiG's rule accounts for severity of disease and past resource consumption. Potential problems and pitfalls are discussed.
journal_name
Appl Health Econ Health Policyjournal_title
Applied health economics and health policyauthors
Gandjour Adoi
10.2165/11586640-000000000-00000subject
Has Abstractpub_date
2011-03-01 00:00:00pages
65-71issue
2eissn
1175-5652issn
1179-1896pii
1journal_volume
9pub_type
杂志文章abstract:BACKGROUND:When pharmaceuticals are administered based on patient characteristics (for example weight or body surface area), an amount of product will be unused and must be disposed of. This wastage represents inefficiency and can distort decision making. METHODS:We present a method for the analysis of optimum fill vo...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0444-0
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Limited empirical evidence exists regarding the effect of price changes on hospital behavior and, ultimately, the quality of care. Additionally, an overview of the results of prior literature is lacking. OBJECTIVE:This study aims to provide a synthesis of existing research concerning the relationship betwee...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-020-00577-6
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Opinions on the use of research abstracts in policy decision making are conflicting. We sought to evaluate the influence of research abstracts in guiding decisions of the Joint Oncology Drug Review of Canada (JODR), which conducts clinical and economic reviews of new cancer treatment drugs for ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/11530510-000000000-00000
更新日期:2010-01-01 00:00:00
abstract::This article deals with the accuracy of statistical records used for political decision making and international comparative analysis. In developing countries, even major macroeconomic indicators can include data inadequacies and methodological differences in data generation between statistical agencies. Existing data...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/11595230-000000000-00000
更新日期:2012-01-01 00:00:00
abstract::A routine part of the process for developing National Institute for Health and Care Excellence (NICE) medical technologies guidance is a submission of clinical and economic evidence by the technology manufacturer. The Birmingham and Brunel Consortium External Assessment Centre (EAC; a consortium of the University of B...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-014-0117-6
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The main purpose of this study is to measure the technical efficiency of twenty health systems in the Middle East and North Africa (MENA) region to inform evidence-based health policy decisions. In addition, the effects of alternative stochastic frontier model specification on the empirical results are examin...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-016-0230-9
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) affects approximately 3 million people in the UK. An 8-week pulmonary rehabilitation (PR) course is recommended under current guidelines. However, studies show that initial benefits diminish over time. OBJECTIVE:We present here an economic evaluation conducted al...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,随机对照试验
doi:10.1007/s40258-015-0199-9
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Total hip replacement (THR) must be managed in a more sustainable manner. More cost-effective surgical techniques and the centralization/regionalization of services are two solutions. The former requires an assessment of newer minimally invasive and muscle-sparing surgical techniques. The latter necessitates...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-016-0260-3
更新日期:2016-12-01 00:00:00
abstract:CONTEXT:The in-hospital costs of extracorporeal membrane oxygenation (ECMO) have not been well established. OBJECTIVE:To evaluate the in-hospital costs of ECMO technology in both US and non-US settings for all patient types. DATA SOURCES:Systematic review of English-language articles, using the PubMed, Embase, Web of...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-015-0170-9
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:From 2000 to 2004, primary care organisations (PCOs) in England were legally required to operate a prescribing incentive scheme for their general practices. A statutory framework specified the types of target, maximum rewards and use of 'good cause for failure' provisions that schemes should include. Our o...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200504020-00005
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is the second most common cancer in Taiwan. For males in Taiwan, it is the most dangerous cancer, with both the highest incidence and mortality rate. OBJECTIVE:To determine cancer-related medical care costs for long-term survivors of HCC. METHODS:The estimation of the lifetim...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200806010-00005
更新日期:2008-01-01 00:00:00
abstract::One focus of health economics is the trade-off between limited resources and the (health) needs of a community. Cost-effectiveness analysis (CEA), while being one of the most accepted evaluation methodologies in health economics, does not account for many important costs and benefits of health care interventions. Some...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Immunization rates for human papillomavirus (HPV) infections remain low among teenagers despite strong evidence of the effectiveness of vaccines. Physician recommendations of the vaccine are far from universal. Several states have enacted policies that mandate HPV vaccination or distribute educational materi...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-016-0225-6
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:There is obscurity regarding how US hospitals determine patients' charges. Whether insurance status influences a patient's hospital charge has not been explored. OBJECTIVE:The objective of this study was to determine whether hospitals charge patients differently based on their insurance status. METHODS:Thi...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-017-0308-z
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to review all published economic evaluations of guideline-based care for chronic wounds and to assess how useful these studies are for decision making in health services. METHODS:Embase, PubMed, Scopus, Health Technology Assessment (HTA) and National Health Service Economic Evaluat...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0403-9
更新日期:2018-10-01 00:00:00
abstract::Smoking of tobacco products is a major public health challenge in prison settings in most countries. Although tobacco use was tolerated by custodial authorities for many decades, the overwhelming evidence of the adverse public health effects of tobacco on both the smokers and those in the vicinity of exhaled or passiv...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract:AIM:To assess the relative cost effectiveness of four strategies (academic detailing, computerised reminder systems, target payments and interactive continuing medical education) to increase the provision of screening and brief interventions by Australian GPs with the ultimate goal of decreasing risky alcohol consumpti...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200605030-00002
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Employers are increasingly relying on rewards programmes in an effort to promote greater levels of activity among employees; however, if enrolment in these programmes is dominated by active employees, then they are unlikely to be a good use of resources. OBJECTIVE:This study uses a stated-preference survey ...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-017-0327-9
更新日期:2017-10-01 00:00:00
abstract::Payment incentives to both consumers and providers have significant consequences for the equity and efficiency of a healthcare system, and have recently come to the fore in health policy reforms. This review first discusses the economic rationale for the apparent international convergence toward payment systems with m...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/00148365-200403010-00009
更新日期:2004-01-01 00:00:00
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journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.2165/11530740-000000000-00000
更新日期:2011-01-01 00:00:00
abstract::This paper examines the use of propensity score matching in economic analyses of observational data. Several excellent papers have previously reviewed practical aspects of propensity score estimation and other aspects of the propensity score literature. The purpose of this paper is to compare the conceptual foundation...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-013-0075-4
更新日期:2014-02-01 00:00:00
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journal_title:Applied health economics and health policy
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
abstract::The mandatory nature of recommendations made by the National Institute for Health and Clinical Excellence (NICE) in the UK has highlighted inherent difficulties in the process of disinvestment in existing technologies to fund NICE-approved technologies. A lack of evidence on candidate technologies means that the proce...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/BF03256137
更新日期:2009-01-01 00:00:00
abstract::Central venous catheters are commonly used to deliver therapies and to monitor patients, and require securing at the point of percutaneous entry to avoid dislodgement. SecurAcath is a catheter securement device designed for central venous catheters. The National Institute for Health and Care Excellence, as a part of i...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-018-0427-1
更新日期:2018-12-01 00:00:00
abstract::This paper critically evaluates the estimates of the cost of Medicare for All (M4A) in the USA. Six studies that estimate the 1-year total cost of M4A in the USA are reviewed. These studies find that M4A would increase national health spending by as much as 16.9% or decrease it by 20.0%, representing a range of estima...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-021-00636-6
更新日期:2021-01-25 00:00:00
abstract::Despite recent initiatives across a number of countries to institutionalise the use of economic evaluation in the assessment of new technologies, the evidence suggests that, to date, the impact of economic analysis on health sector decision making in practice has been low. This paper proposes that incentive compatibil...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract::The Peristeen transanal irrigation system is intended to allow people with bowel dysfunction to flush out the lower part of the bowel as part of their bowel management strategy. Peristeen was the subject of an evaluation by the National Institute for Health and Care Excellence, through its Medical Technologies Evaluat...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-018-0447-x
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The Xpert® MTB/RIF (Xpert) test has been shown to be effective and cost-effective for diagnosing tuberculosis (TB) under conditions with high HIV prevalence and HIV-TB co-infection but less is known about Xpert's cost in low HIV prevalence settings. Cambodia, a country with low HIV prevalence (0.7%), high TB...
journal_title:Applied health economics and health policy
pub_type: 杂志文章
doi:10.1007/s40258-018-0397-3
更新日期:2018-08-01 00:00:00
abstract::Memokath-051 is a thermo-expandable, nickel-titanium alloy spiral stent used to treat ureteric obstruction resulting from malignant or benign strictures. The National Institute for Health and Care Excellence (NICE) selected Memokath-051 for evaluation. The company, PNN Medical, claimed Memokath-051 has clinical superi...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-018-0389-3
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Cervical cancer ranks fourth amongst the commonest malignancies worldwide and the second most prevalent cancer afflicting women in low-to-middle income countries (LMICs), hence, of great public health importance. LMICs are the most affected regions as evidenced by their high prevalence of the disease. Mortal...
journal_title:Applied health economics and health policy
pub_type: 杂志文章,评审
doi:10.1007/s40258-020-00576-7
更新日期:2020-10-01 00:00:00