Effects of divalent cations on bovine testicular hyaluronidase catalyzed transglycosylation of chondroitin sulfates.

abstract：:MicroRNA let-7i is up-regulated in T cells from patients with Ankylosing Spondylitis (AS). In this study, we investigated the role of let-7i in T cells survival. Our results demonstrated down-regulation of insulin-like growth factor-1 receptor (IGF1R) in T cells from patients with AS. Luciferase reporter assay suggest...

journal_title：Biochemical and biophysical research communications

authors： Hou C,Zhu M,Sun M,Lin Y

更新日期：2014-10-31 00:00:00

abstract：:Most formal methods for analyzing the divergent evolution of protein sequences assume a Markov model where position i in a polypeptide chain undergoes amino acid substitution independently from position i + 1. The large number of aligned homologous sequence pairs available from the exhaustive matching of the protein s...

journal_title：Biochemical and biophysical research communications

authors： Gonnet GH,Cohen MA,Benner SA

更新日期：1994-03-15 00:00:00

abstract：:p8 is an 80 amino-acid polypeptide identified because of its remarkable over-expression in the stressed pancreas. This protein, apparently devoid of enzymatic activity, is a powerful regulator of several intracellular pathways, suggesting that it has to interact with several molecular partners to modulate their activi...

journal_title：Biochemical and biophysical research communications

authors： Malicet C,Hoffmeister A,Moreno S,Closa D,Dagorn JC,Vasseur S,Iovanna JL

更新日期：2006-01-06 00:00:00

abstract：:Neocarzinostatin is a radiomimetic antibiotic with a potent cytotoxic effect which elicits a hypersensitive response in human cells homozygous or heterozygous for the gene for ataxia-telangiectasia. The extent and the time course of potentially lethal damage repair and sublethal damage repair following neocarzinostati...

journal_title：Biochemical and biophysical research communications

authors： Shiloh Y,Tabor E,Becker Y

更新日期：1983-01-27 00:00:00

abstract：:Xenopus XmN-cadherin gene appears to have dual functions, since its mRNA is maternally provided in unfertilized eggs, once disappears almost completely during gastrula stage, then accumulates again specifically in neural tissues in later stage embryos. In the present experiment, we first followed the change in XmN-cad...

journal_title：Biochemical and biophysical research communications

authors： Hojyo T,Tooi O,Tashiro K,Shiokawa K

更新日期：1998-01-06 00:00:00

abstract：:The protein kinase C inhibitor C-I reduced superoxide production by human neutrophils in response to phorbol myristate acetate by greater than 50%. In contrast to its effects in oxidative metabolism, 100 microM C-I caused minimal inhibition (5-18%) of lysozyme release in response to phorbol myristate acetate. Enzyme r...

journal_title：Biochemical and biophysical research communications

authors： Salzer W,Gerard C,McCall C

更新日期：1987-10-29 00:00:00

abstract：:Isoprenoids comprise a diverse group of natural products with a broad range of metabolic functions. Isoprenoids are synthesized from prenyl pyrophosphates by prenyltransferases that catalyze the isoprenoid chain-elongation process to different chain lengths. We hereby present the crystal structure of geranylgeranyl py...

journal_title：Biochemical and biophysical research communications

authors： Kim S,Kim EJ,Park JB,Kim SW,Kim KJ

更新日期：2019-10-20 00:00:00

abstract：:ARD1 protein is a mammalian gene product homologous to a yeast Ard1p (Arrest defective 1 protein) acetyltransferase. Although two alternative splicing products of ARD1, ARD1(235) and ARD1(225), were reported in mouse, only ARD1(235) orthologue was reported in humans. Here we show that ARD1(225) is not expressed in hum...

journal_title：Biochemical and biophysical research communications

authors： Chun KH,Cho SJ,Choi JS,Kim SH,Kim KW,Lee SK

更新日期：2007-02-02 00:00:00

abstract：:E-cadherin plays a mechanical role in mediating cell-cell interactions and maintaining epithelial tissue integrity, and the loss of E-cadherin function has been implicated in cancer progression and metastasis. Syndecan-2, a cell-surface heparan sulfate proteoglycan, is upregulated during the development of colon cance...

journal_title：Biochemical and biophysical research communications

authors： Jang B,Jung H,Chung H,Moon BI,Oh ES

更新日期：2016-08-12 00:00:00

abstract：:The effects of graded doses (5 x 10(-8) to 10(-5)) acetylcholine on intracellular Ca2+ and on 86Rb and 36Cl efflux were compared in submandibular cell clusters of 1 and 7 day-old and adult rats. Initial Ca2+ peaks were similar at agonists concentrations lower than 10(-7) M but the release of Rb+ and Cl- were smaller i...

journal_title：Biochemical and biophysical research communications

authors： Seagrave JC,Ramsey RC,Barker S,Martinez JR

更新日期：1992-11-16 00:00:00

abstract：:Prostaglandins are known to be involved in bone metabolism as evidenced by the ability of PGE2 to induce bone resorption. It was, therefore, of interest to determine if there was an association of specific prostaglandin metabolites with the various stages of developing bone by utilizing the matrix-induced endochondral...

journal_title：Biochemical and biophysical research communications

authors： Wientroub S,Wahl LM,Feuerstein N,Winter CC,Reddi AH

更新日期：1983-12-28 00:00:00

abstract：:We present a novel and useful principle that can be applied to enzyme reactions with dilute substrates and enables to obtain the desired time-course curve from the reverse reaction when the latter can be measured more easily. Let us imagine an enzyme mixture that can catalyze the interconversion between substances A, ...

journal_title：Biochemical and biophysical research communications

authors： Kijima S,Kijima H

更新日期：1994-09-15 00:00:00

abstract：:We investigated whether thrombin, the final activator of coagulation cascade, regulates expression of matrix metalloproteinases (MMP)-9 in human monocytes. We show that thrombin stimulation induced MMP-9 secretion of monocytes dose- and time-dependently as revealed by gelatin zymography. Real-time RT-PCR and Western b...

journal_title：Biochemical and biophysical research communications

authors： Chang CJ,Hsu LA,Ko YH,Chen PL,Chuang YT,Lin CY,Liao CH,Pang JH

更新日期：2009-07-24 00:00:00

abstract：:Using minimum energy calculations and molecular dynamics techniques the preferred conformational states of LHRH and its analogues have been reported to involve a modified beta-bend between residues 5 to 8. Based on some of these models cyclic peptide analogues of LHRH antagonists were synthesised using solid phase pep...

journal_title：Biochemical and biophysical research communications

authors： Dutta AS,Gormley JJ,McLachlan PF,Woodburn JR

更新日期：1989-03-31 00:00:00

abstract：:Activation of the classical IκB kinases (IKKα and IKKβ) was previously shown to contribute to obesity-induced inflammation and insulin resistance. Using knockout mice, we investigated whether the related isoform IKKε plays a similar metabolic role. IKKε(-/-) mice had reduced body weight, leptin levels, as well as high...

journal_title：Biochemical and biophysical research communications

authors： Scheja L,Heese B,Seedorf K

更新日期：2011-04-08 00:00:00

abstract：:Mouse mammary carcinoma mutant cell line FUA169, characterized by high GM3 ganglioside content, was established from parent cell line FM3A/F28-7, which has high LacCer content but no GM3. Although both cell lines showed the same quantity and quality of integrin receptors, FUA169 showed much stronger adhesion to fibron...

journal_title：Biochemical and biophysical research communications

authors： Zheng M,Tsuruoka T,Tsuji T,Hakomori S

更新日期：1992-08-14 00:00:00

abstract：:A prolyl isomerase Pin1 deficient (Pin1-/-) male mice had severe testicular atrophy. We investigated the function of Pin1 in spermatogenesis by analyzing the Pin1-/- mice at reproductive age. Pin1-/- mice had lessαPLZF positive spermatogonia (undifferentiated spermatogonia) than wild type (WT). Nevertheless, the Pin1-...

journal_title：Biochemical and biophysical research communications

authors： Kurita-Suzuki A,Kamo Y,Uchida C,Tanemura K,Hara K,Uchida T

更新日期：2018-02-26 00:00:00

abstract：:Heat shock proteins are detectable in human atherosclerotic plaques, especially in endothelial cells. In this report we show by immunofluorescence that incubation "in vitro" with OxLDL is a stress capable of inducing the expression of heat shock protein 70 in both the EAhy-926 cell line and human umbilical vein endoth...

journal_title：Biochemical and biophysical research communications

authors： Zhu W,Roma P,Pellegatta F,Catapano AL

更新日期：1994-04-15 00:00:00

abstract：:Ribosomal proteins must be imported into the nucleus after being synthesized in the cytoplasm. Since the rpS2 amino acid sequence does not contain a typical nuclear localization signal, we used deletion mutant analysis and rpS2-beta-galactosidase chimeric proteins to identify the nuclear targeting domains in rpS2. Nuc...

journal_title：Biochemical and biophysical research communications

authors： Antoine M,Reimers K,Wirz W,Gressner AM,Müller R,Kiefer P

更新日期：2005-09-16 00:00:00

abstract：:BA1544 from Bacillus anthracis was previously annotated as a transcription factor for the gene cluster ba1554 - ba1558, but has not been experimentally characterized. B. anthracis is an obligate pathogen causing fatal inhalational anthrax, and BA1544 is absolutely conserved in Bacillus species, including Bacillus cere...

journal_title：Biochemical and biophysical research communications

authors： Kim MI,Hong M

更新日期：2016-03-25 00:00:00

abstract：:Aminoglycoside phosphotransferases represent a broad class of enzymes that promote bacterial resistance to aminoglycoside antibiotics via the phosphorylation of hydroxyl groups in the latter. Here we report the spatial structure of the 3'-aminoglycoside phosphotransferase of novel VIII class (AphVIII) solved by X-ray ...

journal_title：Biochemical and biophysical research communications

authors： Boyko KM,Gorbacheva MA,Korzhenevskiy DA,Alekseeva MG,Mavletova DA,Zakharevich NV,Elizarov SM,Rudakova NN,Danilenko VN,Popov VO

更新日期：2016-09-02 00:00:00

abstract：:Glycosylation of endothelin (ET) receptors was found to occur in rat cerebellar and atrial membranes. Specifically, we investigated whether the ETA and ETB receptor subtypes differed in their sensitivity to deglycosylation treatment and whether the two affinity states (nanomolar and picomolar) observed in each recepto...

journal_title：Biochemical and biophysical research communications

authors： Shraga-Levine Z,Sokolovsky M

更新日期：1998-05-19 00:00:00

abstract：:Many organisms do not contain the necessary biochemical armoury to carry out the initial oxidative attack of many pollutant chemicals. In the present study, Acinetobacter sp. strain BD413 has been genetically engineered to express the cytochrome P450 xenobiotic-metabolising enzyme CYP105D1 from Streptomyces griseus th...

journal_title：Biochemical and biophysical research communications

authors： Lamb DC,Kelly DE,Masaphy S,Jones GL,Kelly SL

更新日期：2000-09-24 00:00:00

abstract：:Two novel allergens, designated Mal f 2 and Mal f 3 according to the WHO/IUIS Allergen Nomenclature Subcommittee recommendation, were isolated from the lipophilic yeast Malassezia furfur cell extracts and the genes coding for those were cloned. Mal f 2 and Mal f 3 had apparent molecular weights of 21 kDa and 20 kDa, r...

journal_title：Biochemical and biophysical research communications

authors： Yasueda H,Hashida-Okado T,Saito A,Uchida K,Kuroda M,Onishi Y,Takahashi K,Yamaguchi H,Takesako K,Akiyama K

更新日期：1998-07-20 00:00:00

abstract：:We recently reported that oviduct epithelial cells in culture produce endothelin (ET) and postulated that ET could play an important role in the contraction of the oviduct. In the present study using an organ chamber myograph system, we evaluated the contractile effects of ET-1 on bovine oviduct ampullary-isthmus segm...

journal_title：Biochemical and biophysical research communications

authors： Rosselli M,Imthurn B,Macas E,Keller PJ,Dubey RK

更新日期：1994-05-30 00:00:00

abstract：:Cytochromes P450 2E1 of human and minipig origin were examined by absorption spectroscopy under high hydrostatic pressure and by resonance Raman spectroscopy. Human enzyme tends to denature to the P420 form more easily than the minipig form; moreover, the apparent compressibility of the heme active site (as judged fro...

journal_title：Biochemical and biophysical research communications

authors： Anzenbacherova E,Hudecek J,Murgida D,Hildebrandt P,Marchal S,Lange R,Anzenbacher P

更新日期：2005-12-09 00:00:00

abstract：:The complete nucleotide sequence of a novel cathepsin cDNA derived from rat placenta was determined and is termed cathepsin Q. The predicted protein of 343 amino acid is a member of the family C1A protease related to cathepsin L. Rat cathepsin Q and its mouse counterpart were found highly expressed in placenta, wherea...

journal_title：Biochemical and biophysical research communications

authors： Sol-Church K,Frenck J,Mason RW

更新日期：2000-01-27 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) play important roles in osteoblast differentiation and maturation. In mammals, the BMP-induced receptor-regulated Smads form complexes with Smad4. These complexes translocate and accumulate in the nucleus, where they regulate the transcription of various target genes. However, the fu...

journal_title：Biochemical and biophysical research communications

authors： Shimada K,Ikeda K,Ito K

更新日期：2009-12-18 00:00:00

abstract：:Increasing evidence shows that immune-mediated mechanisms may contribute to the pathogenesis of central nervous system disorders including cerebellar ataxias, as indicated by the aberrant production of neuronal surface antibodies. We previously reported a patient with cerebellar ataxia associated with production of a ...

journal_title：Biochemical and biophysical research communications

authors： Yaguchi H,Yabe I,Takahashi H,Watanabe M,Nomura T,Kano T,Matsumoto M,Nakayama KI,Watanabe M,Hatakeyama S

更新日期：2017-12-09 00:00:00

abstract：:Chlorophyllide a oxygenase (CAO) that converts chlorophyllide a to chlorophyllide b was overexpressed in tobacco to increase chlorophyll (Chl) b biosynthesis and alter the Chl a/b ratio. Transgenic plants along with their wild-type cultivars were grown in low and high light intensities. In low light there was 20% incr...

journal_title：Biochemical and biophysical research communications

authors： Pattanayak GK,Biswal AK,Reddy VS,Tripathy BC

更新日期：2005-01-14 00:00:00