Abstract:
:Aging represents a complex remodeling in which both innate and adaptive immunities deteriorate. Age-related changes in humoral immunity are responsible for the reduced vaccine responses observed in elderly individuals. Although T cell alterations play a significant role in age-related humoral immune changes, alterations in B cells also occur. We here provide an overview of age-related changes in B cell markers and functions. Our studies have shown that intrinsic changes in B cells with age contribute to reduced antibody responses such as those to the influenza vaccine.
journal_name
J Clin Immunoljournal_title
Journal of clinical immunologyauthors
Frasca D,Blomberg BBdoi
10.1007/s10875-010-9501-7subject
Has Abstractpub_date
2011-06-01 00:00:00pages
430-5issue
3eissn
0271-9142issn
1573-2592journal_volume
31pub_type
杂志文章,评审abstract::This is the second report on the continuing efforts of LAGID to increase the recognition and registration of patients with primary immunodeficiency diseases in 12 Latin American countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Honduras, Mexico, Panama, Paraguay, Peru, Uruguay, and Venezuela. This report reve...
journal_title:Journal of clinical immunology
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journal_title:Journal of clinical immunology
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abstract::Oligoclonal free light chains (FLC) banding has been described in multiple sclerosis (MS) and should be correlated with disease activity. However, discrepancies between studies have been reported because of differences in methods. A new quantitative, rapid, and automated method using nephelometry is now available. Our...
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journal_title:Journal of clinical immunology
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journal_title:Journal of clinical immunology
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/s10875-005-5257-x
更新日期:2005-09-01 00:00:00
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journal_title:Journal of clinical immunology
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journal_title:Journal of clinical immunology
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/BF00915287
更新日期:1984-01-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/BF00916702
更新日期:1990-09-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章,多中心研究
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更新日期:2016-04-01 00:00:00
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journal_title:Journal of clinical immunology
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更新日期:1991-01-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/s10875-012-9705-0
更新日期:2012-10-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/s10875-012-9803-z
更新日期:2013-02-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
doi:10.1007/s10875-018-0508-9
更新日期:2018-05-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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更新日期:1998-05-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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journal_title:Journal of clinical immunology
pub_type: 杂志文章,多中心研究
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更新日期:2016-08-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章,评审
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更新日期:2019-01-01 00:00:00
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更新日期:2013-01-01 00:00:00
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journal_title:Journal of clinical immunology
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更新日期:2020-12-07 00:00:00
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journal_title:Journal of clinical immunology
pub_type: 杂志文章
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journal_title:Journal of clinical immunology
pub_type: 杂志文章,多中心研究
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更新日期:2011-12-01 00:00:00