Abstract:
OBJECTIVE:To examine the long-term outcome of the stent fracture (SF) and the potential predictive factors contributing to in-stent restenosis (ISR) in the fractured stent. BACKGROUND:The SF is thought to be a higher risk of ISR in drug-eluting stent, although SF does not always develop ISR. METHODS:The consecutive 1,228 de novo lesions in 1,079 patients who underwent sirolimus-eluting stents implantation and assessed by 8 months follow-up coronary angiography were retrospectively analyzed. RESULTS:One hundred and seventeen SFs (9.5%) were identified in 100 patients and 22 (18.8%) SFs revealed ISR at the first follow-up. In addition, 16 (13.7%) developed new ISRs from 95 residual SFs without ISR prior to the second follow-up. Overall, 38 (32.5%) of all 117 SFs developed ISR, and 16 (42.1%) of 38 SFs occurred in a late phase beyond the first 8 months follow-up. A higher risk of ISR in the SF site was associated with the chronic total occlusion (ISR vs. no ISR: 34.2% vs. 16.5%, P = 0.0304), calcified lesions (55.3% vs. 34.2%, P = 0.0299), and correspondence 89.5% versus 43.0%, P < 0.0001 (SF site occurring at the original target lesion site) in the univariate analysis. The correspondence was identified as the only strong predictive factor for ISR at the SF site according to a multivariate logistic regression analysis (odds ratio 12.6, 95% confidence interval 3.82-53.5, P < 0.0001). CONCLUSIONS:SF occurring at the site of the original target lesion was a strong independent predictor of ISR. This indicates the need for a careful, long-term follow-up in those situations, even when no significant ISR is initially detected.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Serikawa T,Kawasaki T,Koga H,Orita Y,Ikeda S,Goto Y,Shintani Y,Kajiwara M,Tanaka H,Fukuyama T,Koga Ndoi
10.1111/j.1540-8183.2010.00614.xsubject
Has Abstractpub_date
2011-04-01 00:00:00pages
165-71issue
2eissn
0896-4327issn
1540-8183journal_volume
24pub_type
杂志文章abstract::Coronary angiography, despite its inherent invasiveness and need for contrast media and radiographic exposure, is still routinely employed every year for the diagnostic and therapeutic management of millions of patients with or at risk for coronary artery disease. Whereas approximate visual estimation is the most comm...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2009.00491.x
更新日期:2009-12-01 00:00:00
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journal_title:Journal of interventional cardiology
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journal_title:Journal of interventional cardiology
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pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00633.x
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00129.x
更新日期:2006-04-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2007.00216.x
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01062.x
更新日期:2002-06-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2008-02-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-12-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
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更新日期:2008-02-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2008.00362.x
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Drug-eluting stents showed a better angiographic and clinical outcome in comparison with bare metal stent in chronic total occlusions (CTOs) percutaneous revascularization, however, great concerns still remain regarding the rate of restenosis and reocclusion in comparison with nonocclusive lesions. AIM:To e...
journal_title:Journal of interventional cardiology
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doi:10.1111/j.1540-8183.2011.00648.x
更新日期:2011-10-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
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更新日期:2002-10-01 00:00:00
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更新日期:2002-02-01 00:00:00
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journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00520.x
更新日期:2010-02-01 00:00:00