Acromegaly as a cause of 1,25-dihydroxyvitamin D-dependent hypercalcemia: case reports and review of the literature.

abstract：:Oral estrogens reduce GH-induced IGF-1 production and preliminary studies have shown that adjuvant estroprogestin (EP) therapy with octreotide LAR may control disease activity in some female patients who are partially responsive to octreotide LAR. Our aim was to verify if EP alone or in combination with octreotide LAR...

journal_title：Pituitary

authors： Vallette S,Serri O

更新日期：2010-12-01 00:00:00

abstract：:We evaluated the efficacy of Gamma knife stereotactic radiosurgery (GKSR) as an adjunctive management modality for patients with drug resistant or intolerant cavernous sinus invasive prolactinomas. Twenty-two patients with cavernous sinus invasive prolactinoma underwent GKSR between 1994 and 2009. Thirteen patients we...

journal_title：Pituitary

authors： Liu X,Kano H,Kondziolka D,Park KJ,Iyer A,Shin S,Niranjan A,Flickinger JC,Lunsford LD

更新日期：2013-03-01 00:00:00

abstract：:In this case report we describe a 38 year-old-female with galactorrhea several months after the birth of an anencephalic child. She had hyperpolactemia and imaging of the pituitary gland revealed a midline defect and a nasopharyngeal mass compatible with a meningo-(hypophyso-) encephalocele and possibly an ectopic ter...

journal_title：Pituitary

authors： Rabelink NM,Lips P,Castelijns JA

更新日期：2012-12-01 00:00:00

abstract：:Lactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas, constitute nearly 80% of functioning pituitary tumors and about 30-50% of all adenomas in the clinical practice. Lactotroph adenomas occur in the general population at a prevalence of 45/100,000, are more common in women, but also involve...

journal_title：Pituitary

authors： Lopes MBS

更新日期：2020-02-01 00:00:00

abstract：:In this report we emphasize the opportunity of considering the uncommon causes of chronic GH-excess in the initial diagnostic process, such as GHRH hypersecretion, especially in the presence of ambiguous pituitary neuroimaging. This topic may have an important clinical significance in order to plan the most cost-effec...

journal_title：Pituitary

authors： Verrua E,Ronchi CL,Ferrante E,Ferrari DI,Bergamaschi S,Ferrero S,Zatelli MC,Branca V,Spada A,Beck-Peccoz P,Lania AG

更新日期：2010-09-01 00:00:00

abstract：:The modern views on the anatomical and physiological interactions between the hypothalamus, pituitary and thyroid gland have emerged only in the last fifty years, although their historical roots may be found in a number of ancient and still not widely known ideas and observations. The regulation of energy body stores ...

journal_title：Pituitary

authors： Toni R

更新日期：2000-10-01 00:00:00

abstract：:The molecular pathogenesis of prolactinomas has resisted elucidation; with the exception of a RAS mutation in a single aggressive prolactinoma, no mutational changes have been identified. In prolactinomas, a further obstacle has been the paucity of surgical specimens suitable for molecular analysis since prolactionoma...

journal_title：Pituitary

authors： Evans CO,Moreno CS,Zhan X,McCabe MT,Vertino PM,Desiderio DM,Oyesiku NM

更新日期：2008-01-01 00:00:00

abstract：:To study the currently available data of recurrence rates of functioning and nonfunctioning pituitary adenomas following surgical cure and to analyze associated predisposing factors, which are not well established. A systematic literature search was conducted using Medline, Embase, Web of Science and the Cochran Libra...

journal_title：Pituitary

authors： Roelfsema F,Biermasz NR,Pereira AM

更新日期：2012-03-01 00:00:00

abstract：:160 clinically non-secreting pituitary adenomas were examined in regard to their expression of the markers PCNA, bcl2, Ki 67 in the mib-1 modification and p53 which are still under investigation for their relevance to cell proliferation. The series contained 60 null cell adenomas, 60 oncocytomas and 40 gonadotroph ade...

journal_title：Pituitary

authors： Schreiber S,Saeger W,Lüdecke DK

更新日期：1999-05-01 00:00:00

abstract：INTRODUCTION:In order to perform trans-sphenoidal endoscopic pituitary surgery safely and efficiently it is important to identify anatomical and pituitary disease features on the pre-operative CT and MRI scans; thereby minimising the risk to surrounding structures and optimising outcomes. We aim to create a checklist t...

journal_title：Pituitary

authors： Twigg V,Carr SD,Balakumar R,Sinha S,Mirza S

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The growing interest in the molecular and genetic alterations of craniopharyngiomas (CPs) is embodied in recent studies revealing insights into the CP tumorigenesis and identifying novel molecular pathways amenable of targeted therapies. The actual impact of this new information, however, remains inconclusiv...

journal_title：Pituitary

authors： Prieto R,Pascual JM

更新日期：2018-08-01 00:00:00

abstract：:We describe two young men with cystic pituitary enlargement on magnetic resonance imaging (MRI) causing hypopituitarism. The first patient presented acutely unwell with headache and vomiting associated with anterior and posterior pituitary dysfunction. The second patient presented with hypopituitarism after a long his...

journal_title：Pituitary

authors： Burt MG,Morey AL,Turner JJ,Pell M,Sheehy JP,Ho KK

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Hypophysitis develops in up to 19% of melanoma patients treated with ipilimumab, a cytotoxic T-lymphocyte antigen-4 antibody. Early detection may avert life-threatening hypopituitarism. We aimed to assess the incidence of ipilimumab-induced hypophysitis (IH) at a quaternary melanoma referral centre, and to dete...

journal_title：Pituitary

authors： De Sousa SMC,Sheriff N,Tran CH,Menzies AM,Tsang VHM,Long GV,Tonks KTT

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Xanthogranulomas are inflammatory masses most commonly found at peripheral sites such as the skin. Sellar and parasellar xanthogranulomas are rare and present a diagnostic challenge as they are difficult to differentiate from other sellar lesions such as craniopharyngiomas and Rathke's cleft cysts pre-operat...

journal_title：Pituitary

authors： Ved R,Logier N,Leach P,Davies JS,Hayhurst C

更新日期：2018-06-01 00:00:00

abstract：:Familial neurohypophyseal diabetes insipidus (FNDI) is mostly an autosomal dominant inherited disorder presenting with severe polydipsia and polyuria typically in early childhood. To date, 69 different variations in the AVP gene encoding the AVP prohormone have been identified in autosomal dominant FNDI (adFNDI). In t...

journal_title：Pituitary

authors： Birkegaard C,Christensen JH,Falorni A,Marzotti S,Minarelli V,Gregersen N,Rittig S

更新日期：2013-06-01 00:00:00

abstract：:Symptomatic cerebral vasospasm (CVS) after transsphenoidal surgery (TSS) is very rare compared with vasospasm resulting from aneurysmal subarachnoid hemorrhage (SAH). Fewer than six cases documented by cerebral angiography have been reported. We evaluated the records of 15 patients in whom SAH developed after TSS. The...

journal_title：Pituitary

authors： Kim EH,Oh MC,Kim SH

更新日期：2013-06-01 00:00:00

abstract：INTRODUCTION:Cushing's syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality. MATERIALS AND METHODS:This review summarizes the main manifestations of Cushing's syndrome (active or in remission) with particu...

journal_title：Pituitary

authors： Ntali G,Grossman A,Karavitaki N

更新日期：2015-04-01 00:00:00

abstract：:Non-functioning pituitary carcinomas (NFPC) are defined as tumours of adenophyseal origin with craniospinal or systemic dissemination, with the absence of a hormonal hypersecretion syndrome. These are a histologically heterogenous group of tumours, comprising gonadotroph, null cell, "silent" tumours of corticotroph, s...

journal_title：Pituitary

authors： Lenders N,McCormack A

更新日期：2018-04-01 00:00:00

abstract：:The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specializa...

journal_title：Pituitary

authors： Nassiri F,Cusimano M,Zuccato JA,Mohammed S,Rotondo F,Horvath E,Syro LV,Kovacs K,Lloyd RV

更新日期：2013-09-01 00:00:00

abstract：:The simultaneous occurrence of a hypothalamic and sellar gangliocytoma with a pituitary prolactinoma is very rare. The explanation for such an association is not known. We describe the case of a woman who had a coexisting adjacent pituitary prolactinoma and gangliocytoma within the same sellar mass. The tumor cells of...

journal_title：Pituitary

authors： Serri O,Berthelet F,Bélair M,Vallette S,Asa SL

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:Tatton-Brown-Rahman syndrome (TBRS) is a newly defined genetic entity characterized by overgrowth and intellectual disability, resulting from germline mutations in the gene encoding DNA methyltransferase 3 alpha (DNMT3A). Affected individuals with benign and malignant tumors have been reported; to our knowledge...

journal_title：Pituitary

authors： Hage C,Sabini E,Alsharhan H,Fahrner JA,Beckers A,Daly A,Salvatori R

更新日期：2020-04-01 00:00:00

abstract：:Arterial bleeding during transsphenoidal surgery for pituitary adenoma is known complication. This usually happens due to rupture of intracavernous carotid or delayed hemorrhage due to the carotico-cavernous fistula and/or pseudoaneurysm. There is also evidence that cavernous carotid aneurysms may occur with pituitary...

journal_title：Pituitary

authors： Berker M,Aghayev K,Saatci I,Palaoğlu S,Onerci M

更新日期：2010-06-01 00:00:00

abstract：:Lanreotide depot (LD; commercial name Somatuline(®) Depot) is an injectable, extended-release formulation of the synthetic somatostatin analog (SSA) lanreotide. In recent clinical trials, LD was found to be suitable for self or partner administration, avoiding the need to travel to a medical facility. The Somatuline(®...

journal_title：Pituitary

authors： Salvatori R,Woodmansee WW,Molitch M,Gordon MB,Lomax KG

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Suprasellar pituitary adenomas (SPAs) are a special type of pituitary adenoma. Although dozens of SPA cases have been reported, the exact definition and the characteristics of SPA have not been exhaustively discussed before. METHODS:In a retrospective electronic medical records review, 13 patients with SPA ...

journal_title：Pituitary

authors： Zhu J,Wang Z,Zhang Y,Liu J,Li X,Deng K,Lu L,Yao Y

更新日期：2020-08-01 00:00:00

abstract：:We report the case of a B-cell type pituitary lymphoma in a 65 year-old male immunocompetent patient who presented with hypogonadotropic hypogonadism and central hypothyroidism and subsequently developed pulmonary lymphoma. Only three cases of pituitary lymphoma have been previously reported, one in a patient with acq...

journal_title：Pituitary

authors： Mathiasen RA,Jarrahy R,Cha ST,Kovacs K,Herman VS,Ginsberg E,Shahinian HK

更新日期：2000-05-01 00:00:00

abstract：:We report the case of a 60 year old male who complained of headache and blurry vision--that progressed to left ophthalmoplegia and ptosis--after receiving a dose of leuprolide for Prostate cancer therapy. Imaging showed a hemorrhagic sellar mass. The patient underwent transsphenoidal debulking, and the tissue obtained...

journal_title：Pituitary

authors： Guerra Y,Lacuesta E,Marquez F,Raksin PB,Utset M,Fogelfeld L

更新日期：2010-01-01 00:00:00

abstract：:Apart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenom...

journal_title：Pituitary

authors： Bakhtiar Y,Hanaya R,Tokimura H,Hirano H,Oyoshi T,Fujio S,Bohara M,Arita K

更新日期：2014-04-01 00:00:00

abstract：:Clinically inapparent adrenal masses, or adrenal incidentalomas, are discovered inadvertently in the course of workup or treatment of unrelated disorders. Cortical adenoma is the most frequent type of adrenal incidentaloma accounting for approximately 50% of cases in surgical series and even greater shares in medical ...

journal_title：Pituitary

authors： Terzolo M,Reimondo G,Bovio S,Angeli A

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Severe fluctuations in plasma sodium concentration and plasma osmolarity, including central diabetes insipidus (CDI), may have significant influence on postoperative morbidity and mortality after pediatric brain tumor surgery.The aim of this study was to describe the frequency, severity and neurological consequ...

journal_title：Pituitary

authors： Kruis RWJ,Schouten-van Meeteren AYN,Finken MJJ,Oostdijk W,van Trotsenburg ASP,Boot AM,Claahsen-van der Grinten HL,van Lindert EJ,Han KS,Hoving EW,Michiels EMC,van Santen HM

更新日期：2018-08-01 00:00:00

abstract：:We report on a 74-year-old male patient who presented with progressive neuroophthalmologic symptoms soon after the administration of a long-acting gonadotropin-releasing hormone agonist for treatment of a prostate cancer. Imaging revealed a destructively growing and extensively calcified sellar mass inconsistent with ...

journal_title：Pituitary

authors： Sahli R,Christ E,Kuhlen D,Giger O,Vajtai I

更新日期：2011-12-01 00:00:00