Effect of methamphetamine dependence on heart rate variability.

abstract：:Mixing alcohol with caffeinated energy drinks is a common practice, especially among young people. In humans, the research on this issue has mainly focused on the use of the mass-marketed energy drinks themselves, whereas in animal models, it has focused on the individual effects of their active ingredients (i.e. caff...

journal_title：Addiction biology

authors： Roldán M,Echeverry-Alzate V,Bühler KM,Sánchez-Diez IJ,Calleja-Conde J,Olmos P,Boehm SL,Maldonado R,Rodríguez de Fonseca F,Santiago C,Gómez-Gallego F,Giné E,López-Moreno JA

更新日期：2018-09-01 00:00:00

abstract：:Extracellular glycine modulates accumbal dopamine levels as well as ethanol-induced dopamine overflow. Glycine availability is also crucial for regulating alcohol consumption and the glycine transporter 1 (GlyT-1) inhibitor Org25935 robustly decreases alcohol intake in rats. To explore whether the alcohol-intake reduc...

journal_title：Addiction biology

authors： Lidö HH,Marston H,Ericson M,Söderpalm B

更新日期：2012-09-01 00:00:00

abstract：:Maladaptive cortical plasticity has been described in individuals with heroin and methamphetamine addiction and may mediate other substance abuse disorders. It is unknown whether cannabis dependence in humans alters the capacity for induction of cortical plasticity. The aim of this study was to non-invasively investig...

journal_title：Addiction biology

authors： Martin-Rodriguez JF,Ruiz-Veguilla M,Alvarez de Toledo P,Aizpurua-Olaizola O,Zarandona I,Canal-Rivero M,Rodriguez-Baena A,Mir P

更新日期：2020-04-23 00:00:00

abstract：:Abuse of Δ⁹-THC by females during adolescence may produce long-term deficits in complex behavioral processes such as learning, and these deficits may be affected by the presence of ovarian hormones. To assess this possibility, 40 injections of saline or 5.6 mg/kg of Δ⁹-THC were administered i.p. daily during adolescen...

journal_title：Addiction biology

authors： Winsauer PJ,Daniel JM,Filipeanu CM,Leonard ST,Hulst JL,Rodgers SP,Lassen-Greene CL,Sutton JL

更新日期：2011-01-01 00:00:00

abstract：:We demonstrated that the genotype of the variable number tandem repeats (VNTRs) in the linked polymorphic region (LPR) of the 5' promoter and in the intron 2 (Stin2) transcriptional regulatory domains of the serotonin transporter SLC6A4 gene determined its promoter interactions with transcription factors and co-activa...

journal_title：Addiction biology

authors： Vasiliou SA,Ali FR,Haddley K,Cardoso MC,Bubb VJ,Quinn JP

更新日期：2012-01-01 00:00:00

abstract：:Previous studies on acetaldehyde dehydrogenase 2 (ALDH2) focused on drinking behavior or alcoholism because the ALDH2*2 allele protects against the risk of developing alcoholism. The mechanism provides that the ALDH2 gene's protective effect is also involved in dopamine metabolism. The interaction of the ALDH2 gene wi...

journal_title：Addiction biology

authors： Lu RB,Lee JF,Huang SY,Lee SY,Chang YH,Kuo PH,Chen SL,Chen SH,Chu CH,Lin WW,Wu PL,Ko HC

更新日期：2012-09-01 00:00:00

abstract：:Activation of brain microglial cells, microgliosis, has been linked to methamphetamine (MA)-seeking behavior, suggesting that microglia could be a new therapeutic target for MA use disorder. Animal data show marked brain microglial activation following acute high-dose MA, but microglial status in human MA users is unc...

journal_title：Addiction biology

authors： Rathitharan G,Truong J,Tong J,McCluskey T,Meyer JH,Mizrahi R,Warsh J,Rusjan P,Kennedy JL,Houle S,Kish SJ,Boileau I

更新日期：2021-01-01 00:00:00

abstract：:Inhibitory optogenetics was used to examine the roles of the prelimbic cortex (PL), the nucleus accumbens core (NAcore) and the PL projections to the NAcore in the reinstatement of cocaine seeking. Rats were microinjected into the PL or NAcore with an adeno-associated virus containing halorhodopsin or archaerhodopsin....

journal_title：Addiction biology

authors： Stefanik MT,Moussawi K,Kupchik YM,Smith KC,Miller RL,Huff ML,Deisseroth K,Kalivas PW,LaLumiere RT

更新日期：2013-01-01 00:00:00

abstract：:Identifying addicts with higher risk of relapse would provide the opportunity to implement individualized interventions and increase cessation success rates. Unfortunately, the ability to predict the long-term success of drug cessation treatments continues to elude researchers. We tested whether brain responses to emo...

journal_title：Addiction biology

authors： Versace F,Lam CY,Engelmann JM,Robinson JD,Minnix JA,Brown VL,Cinciripini PM

更新日期：2012-11-01 00:00:00

abstract：:The present study was undertaken to examine whether genetically predetermined differences in components of the endocannabinoid system were present in the brain of Sardinian alcohol-preferring (sP) and Sardinian alcohol-non-preferring (sNP) rats, a pair of rat lines selectively bred for opposite alcohol preference. The...

journal_title：Addiction biology

authors： Vinod KY,Maccioni P,Garcia-Gutierrez MS,Femenia T,Xie S,Carai MA,Manzanares J,Cooper TB,Hungund BL,Colombo G

更新日期：2012-01-01 00:00:00

abstract：:Obesity represents an important risk factor contributing to the global burden of disease. The current obesogenic environment with easy access to calorie-dense foods is fueling this obesity epidemic. However, how these foods contribute to the progression of feeding behavior changes that lead to overeating is not well u...

journal_title：Addiction biology

authors： Espinosa-Carrasco J,Burokas A,Fructuoso M,Erb I,Martín-García E,Gutiérrez-Martos M,Notredame C,Maldonado R,Dierssen M

更新日期：2018-03-01 00:00:00

abstract：:Neuroimaging studies suggested that drug addiction is linked to abnormal brain functional connectivity. However, little is known about the alteration of brain white matter (WM) connectivity in addictive drug users and nearly no study has been performed to examine the alterations of brain WM connectivity in heroin-depe...

journal_title：Addiction biology

authors： Zhang R,Jiang G,Tian J,Qiu Y,Wen X,Zalesky A,Li M,Ma X,Wang J,Li S,Wang T,Li C,Huang R

更新日期：2016-05-01 00:00:00

abstract：:The aim of this study was to profile and compare blood naltrexone and 6-beta-naltrexol levels with time following treatment with two sustained-release naltrexone preparations produced by GoMedical Industries, Australia at a community heroin treatment clinic in Perth, Western Australia. A sample of 10 patients who each...

journal_title：Addiction biology

authors： Hulse GK,Arnold-Reed DE,O'Neil G,Chan CT,Hansson R,O'Neil P

更新日期：2004-03-01 00:00:00

abstract：:Nicotine withdrawal is associated with subtle working memory deficits that predict subsequent relapse. We examined the neural substrates underlying these processes in treatment-seeking smokers, and explored the moderating influence of age on abstinence-induced alterations in brain activity and performance. Sixty-three...

journal_title：Addiction biology

authors： Falcone M,Wileyto EP,Ruparel K,Gerraty RT,LaPrate L,Detre JA,Gur R,Loughead J,Lerman C

更新日期：2014-09-01 00:00:00

abstract：:Chronic and excessive alcohol consumption induces defined myocardial lesions characterized by impaired structural, mechanical and biochemical features. The pathogenic mechanisms are unknown, although it is possible that protein adduct formation by reactive metabolites of ethanol may be a contributory process. Hitherto...

journal_title：Addiction biology

authors： Worrall S,Richardson PJ,Preedy VR

更新日期：2000-10-01 00:00:00

abstract：:Reduced executive control is one of the central components of model on the development and maintenance of Internet gaming disorder (IGD). Among the various executive control problems, high impulsivity has consistently been associated with IGD. We performed voxel-based morphometric analysis with diffeomorphic anatomica...

journal_title：Addiction biology

authors： Lee D,Namkoong K,Lee J,Jung YC

更新日期：2018-09-01 00:00:00

abstract：:Although the notion that alcohol promotes violence is widespread, not all individuals are aggressive while intoxicated. Genetic variation could be a contributing factor to individual differences in alcohol-heightened aggression. The present study examines the effects of OPRM1C77G genotype on responses to threat in rhe...

journal_title：Addiction biology

authors： Driscoll CA,Lindell SG,Schwandt ML,Suomi SJ,Higley JD,Heilig M,Barr CS

更新日期：2017-11-01 00:00:00

abstract：:Erythroycte delta aminolevulinic acid dehydratase (ALAD) has been suggested as a marker for detecting recent alcohol intake. Unlike other markers, ALAD activity decreases after alcohol intake. Review of the literature suggests that the main interest in this marker is because it increases rapidly after withdrawal. The ...

journal_title：Addiction biology

authors： Aubin HJ,Laureaux C,Tilikete S,Gillet C,Lepetitcorps A,Nguyen T,Troupel S,Paille F,Barrucand D

更新日期：1997-04-01 00:00:00

abstract：:Numerous studies have explored the morphological differences of the brain between subjects with alcohol use disorder (AUD) and control subjects, but very few have investigated the impact of the duration of alcohol use disorder (DAD) and current level of alcohol consumption (CAC) within AUD subjects using magnetic reso...

journal_title：Addiction biology

authors： Rolland B,Dricot L,Creupelandt C,Maurage P,De Timary P

更新日期：2020-03-01 00:00:00

abstract：:We measured hippocampal volumes and cognitive functioning in crack-cocaine and crack-cocaine/alcoholdependent subjects (abstinent approximately 10-12 weeks) compared to age-matched controls. Cognitive function was evaluated using the computerized MicroCog Assessment of Cognitive Functioning (which includes tests of ex...

journal_title：Addiction biology

authors： DI Sclafani V,Truran DL,Bloomer C,Tolou-Shams M,Clark HW,Norman D,Hannauer D,Fein G

更新日期：1998-07-01 00:00:00

abstract：:In light of the upcoming eleventh edition of the International Classification of Diseases (ICD-11), the question arises as to the most appropriate classification of 'Pathological Gambling' ('PG'). Some academic opinion favors leaving PG in the 'Impulse Control Disorder' ('ICD') category, as in ICD-10, whereas others a...

journal_title：Addiction biology

authors： Fauth-Bühler M,Mann K,Potenza MN

更新日期：2017-07-01 00:00:00

abstract：:Polymorphism of a variable number of tandem repeats (VNTR) in the 3' untranslated region of exon 15 of the SLC6A3 gene, coding for the dopamine transporter (DAT), was analysed to test whether length variation contributes to differences in the individual susceptibility to aggressive - criminal behaviour and liability t...

journal_title：Addiction biology

authors： Gerra G,Garofano L,Pellegrini C,Bosari S,Zaimovic A,Moi G,Avanzini P,Talarico E,Gardini F,Donnini C

更新日期：2005-09-01 00:00:00

abstract：:Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol dependence syndrome (ADS) in East Asian populations. Recently, attention has focused on the role of these SNPs in determining ADS risk in European populations. To ...

journal_title：Addiction biology

authors： Way M,McQuillin A,Saini J,Ruparelia K,Lydall GJ,Guerrini I,Ball D,Smith I,Quadri G,Thomson AD,Kasiakogia-Worlley K,Cherian R,Gunwardena P,Rao H,Kottalgi G,Patel S,Hillman A,Douglas E,Qureshi SY,Reynolds G,Jauhar S

更新日期：2015-05-01 00:00:00

abstract：:Nicotine, the primary addictive component of tobacco, affects the mammalian brain. Smokers' brains have smaller cortical grey matter volumes and/or lower densities compared with non-smokers'. Differences in subcortical structures like the striatum are however, less clear. A high concentration of nicotinic receptors ma...

journal_title：Addiction biology

authors： Das D,Cherbuin N,Anstey KJ,Sachdev PS,Easteal S

更新日期：2012-07-01 00:00:00

abstract：:The genetic and environmental contributions to differences in response to ethanol have been examined widely using inbred strains, selected lines and genetically engineered (transgenic and 'knock-out') animals. In addition, recombinant inbred strains have been used to identify QTLs (chromosomal regions) associated with...

journal_title：Addiction biology

authors： Hoffman P,Tabakoff B

更新日期：2005-03-01 00:00:00

abstract：:Copy number variations (CNVs) can alter the DNA sequence in blocks ranging from kilobases to megabases, involving more total nucleotides than single nucleotide polymorphisms. Yet, its impact in humans is far from fully understood. In this study, we investigate the relationship of genome-wide CNVs with brain function e...

journal_title：Addiction biology

authors： Liu J,Calhoun VD,Chen J,Claus ED,Hutchison KE

更新日期：2013-05-01 00:00:00

abstract：:Smoking withdrawal is associated with significant deficits in the ability to initiate and maintain attention for extended periods of time (i.e. sustained attention; SA). However, the effects of smoking abstinence on the temporal dynamics of neurocognition during SA have not been evaluated. Twenty adult smokers underwe...

journal_title：Addiction biology

authors： Kozink RV,Lutz AM,Rose JE,Froeliger B,McClernon FJ

更新日期：2010-10-01 00:00:00

abstract：:Adolescence is characterized by considerable brain maturation that coincides with the development of adult behavior. Binge drinking is common during adolescence and can have deleterious effects on brain maturation because of the heightened neuroplasticity of the adolescent brain. Using an animal model of adolescent in...

journal_title：Addiction biology

authors： Vetreno RP,Yaxley R,Paniagua B,Crews FT

更新日期：2016-07-01 00:00:00

abstract：:Frustration represents a particular aspect of the addictive process that is related to loss of control when the expected reward is not obtained. We aim to study the consequences of frustrated expected reward on gene expression in the mouse brain. For this purpose, we used an operant model of frustration using palatabl...

journal_title：Addiction biology

authors： Martín-García E,Fernández-Castillo N,Burokas A,Gutiérrez-Cuesta J,Sánchez-Mora C,Casas M,Ribasés M,Cormand B,Maldonado R

更新日期：2015-01-01 00:00:00

abstract：:Behavioral sensitization to cocaine is associated to neuroadaptations that contribute to addiction. Enkephalin is highly expressed in mesocorticolimbic areas associated with cocaine-induced sensitization; however, their influence on cocaine-dependent behavioral and neuronal plasticity has not been explained. In this s...

journal_title：Addiction biology

authors： Mongi-Bragato B,Zamponi E,García-Keller C,Assis MA,Virgolini MB,Mascó DH,Zimmer A,Cancela LM

更新日期：2016-03-01 00:00:00