Standing at the crossroads between new and historically prevalent heart disease: effects of migration and socio-economic factors in the Heart of Soweto cohort study.

abstract：:Between January 1983 and December 1990, 20 patients aged 80 years or older underwent valvular surgery. The patients' ages varied from 80 to 87 years (mean, 82 +/- 1.5 years). The indication for operation was aortic stenosis in 19 patients, and mitral insufficiency after previous mitral valve replacement with a biopros...

journal_title：European heart journal

authors： Pasic M,Carrel T,Laske A,Bauer E,Turina J,Jenni R,von Segesser L,Turina M

更新日期：1992-04-01 00:00:00

abstract：:A previously described nitroglycerin-induced heparin resistance could not be verified by in-vitro experiments or in a randomized, double-blind, crossover trial in healthy volunteers. A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin ...

journal_title：European heart journal

authors： Schoenenberger RA,Ménat L,Weiss P,Marbet GA,Ritz R

更新日期：1992-03-01 00:00:00

abstract：AIMS:Genome-wide association studies have previously identified INSIG2 as a candidate gene for plasma low-density lipoprotein cholesterol (LDL-c). However, we suspect a role for CCDC93 in the same locus because of its involvement in the recycling of the LDL-receptor (LDLR). METHODS AND RESULTS:Characterization of the ...

journal_title：European heart journal

authors： Rimbert A,Dalila N,Wolters JC,Huijkman N,Smit M,Kloosterhuis N,Riemsma M,van der Veen Y,Singla A,van Dijk F,Biobank-Based Integrative Omics Studies Consortium.,Frikke-Schmidt R,Burstein E,Tybjærg-Hansen A,van de Sluis B,Kui

更新日期：2020-03-01 00:00:00

abstract：AIMS:We investigated the temporal changes in circulating levels of markers of extracellular cardiac matrix (ECCM) turnover and their relationship with infarct size (IS), ejection fraction (EF), and left ventricular (LV) volumes, determined by serial cardiac magnetic resonance (CMR) imaging in patients with first-time S...

journal_title：European heart journal

authors： Manhenke C,Ueland T,Jugdutt BI,Godang K,Aukrust P,Dickstein K,Ørn S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:We evaluated prognostic value at 6 months of residual pulmonary vascular obstruction (RPVO) measured before discharge in patients with intermediate- or high-risk pulmonary embolism (PE). METHODS AND RESULTS:Prospective registry including 416 consecutive patients with intermediate- or high-risk PE who surviv...

journal_title：European heart journal

authors： Meneveau N,Ider O,Seronde MF,Chopard R,Davani S,Bernard Y,Schiele F

更新日期：2013-03-01 00:00:00

abstract：:The author reviews statistical methods commonly applied in economic evaluations that rely on individual patient-level data. The paper includes a review of foundational concepts, unique characteristics of health economic data, and methods developed to address them. The paper then highlights issues that should be consid...

journal_title：European heart journal

authors： Reed SD

更新日期：2014-07-01 00:00:00

abstract：AIMS:Magnetic resonance imaging (MRI) is well established as an important diagnostic tool in medicine. However, the presence of a cardiac pacemaker is usually regarded as a contraindication for MRI due to safety reasons. In this study, heating effects at the myocardium-pacemaker lead tip interface have been investigate...

journal_title：European heart journal

authors： Luechinger R,Zeijlemaker VA,Pedersen EM,Mortensen P,Falk E,Duru F,Candinas R,Boesiger P

更新日期：2005-02-01 00:00:00

abstract：:Antithrombotic therapy and invasive risk stratification in selected high-risk patients have improved outcomes from non-ST-segment elevation acute coronary syndromes (NSTE-ACS), but carry a risk of bleeding and blood transfusion. Although the true incidence of bleeding depends on the population studied (i.e. clinical t...

journal_title：European heart journal

authors： Rao SV,Eikelboom JA,Granger CB,Harrington RA,Califf RM,Bassand JP

更新日期：2007-05-01 00:00:00

abstract：:Experience accumulated from several large trials strongly suggests that beta-blockers should be used for the management of chronic heart failure[87]. It is appropriate to add beta-blockade to conventional therapy such as diuretics, ACE inhibitors and digoxin, as this was the approach used in the major trials. It is ap...

journal_title：European heart journal

authors： Cleland JG,Bristow MR,Erdmann E,Remme WJ,Swedberg K,Waagstein F

更新日期：1996-11-01 00:00:00

abstract：:Hypertension induced in rats by suprarenal banding has a blood pressure elevating effect that is accompanied by the occurrence of cardiac hypertrophy and fibrosis. This phenomenon is already present at 2 weeks after banding and persists up to 1.5 years. The increase in cardiac weight is mostly due to the development o...

journal_title：European heart journal

authors： Nagasawa K,Zimmermann R,Münkel B,Linz W,Schölkens B,Schaper J

更新日期：1995-05-01 00:00:00

abstract：:Myocardial bridging of the left anterior descending coronary artery producing complete systolic occlusion was demonstrated in a patient with hypertrophic cardiomyopathy, who had localized myocardial hypertrophy in the lateral left ventricular wall outside the territory of that artery. Although a cause and effect relat...

journal_title：European heart journal

authors： Doi YL,Yamada M,Hamashige N,Yonezawa Y,Odawara H,Ozawa T

更新日期：1987-07-01 00:00:00

abstract：:Echocardiographic parameters of left ventricular (LV) function were compared with the electrocardiographic findings in 40 patients with chronic severe aortic regurgitation. Total 12-lead QRS amplitude was linearly correlated with LV mass and its 'relative reduction' (less than 250 mm) indicated LV hypertrophy. Patient...

journal_title：European heart journal

authors： Scognamiglio R,Fasoli G,Bruni A,Dalla-Volta S

更新日期：1988-01-01 00:00:00

abstract：:In the near future, the practice of cardiology in Europe will be strongly influenced by a complex interplay of epidemiological, social, economical, professional, and technological evolving factors. The present report summarizes the conclusions of an expert conference organized by the European Society of Cardiology to ...

journal_title：European heart journal

authors： Escaned J,Rydén L,Zamorano JL,Poole-Wilson P,Fuster V,Gitt A,Fernández-Avilés F,Scholte Op Reimer W,de Teresa E,Alonso-Pulpón L,Tendera M,European Conference on the Future of Cardiology.

更新日期：2007-03-01 00:00:00

abstract：AIMS:In patients with sick sinus syndrome, bradycardia can be treated with a single-lead pacemaker or a dual-chamber pacemaker. Previous trials have revealed that pacing modes preserving atrio-ventricular synchrony are superior to single-lead ventricular pacing, but it remains unclear if there is any difference between...

journal_title：European heart journal

authors： Nielsen JC,Thomsen PE,Højberg S,Møller M,Vesterlund T,Dalsgaard D,Mortensen LS,Nielsen T,Asklund M,Friis EV,Christensen PD,Simonsen EH,Eriksen UH,Jensen GV,Svendsen JH,Toff WD,Healey JS,Andersen HR,DANPACE Investigato

更新日期：2011-03-01 00:00:00

abstract：:In the initial phase of heart failure, cardiac output and pressure are maintained by increasing sympathetic drive and by cell hypertrophy. Elevated end-diastolic volume, a reduced ejection fraction and a higher filling pressure also occur. Only in more severe heart failure, when cardiac output cannot be maintained, do...

journal_title：European heart journal

authors： Burkart F

更新日期：1995-07-01 00:00:00

abstract：AIMS:The extent to which hospital and geographic characteristics influence the time course of uptake of evidence from key clinical trials and practice guidelines is unknown. The gap between evidence and practice is well recognized but the factors influencing this disjunction, and the extent to which such factors are mo...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Anderson FA Jr,Granger CB,Moscucci M,Flather MD,Spencer F,Budaj A,Dabbous OH,Gore JM,GRACE Investigators.

更新日期：2003-08-01 00:00:00

abstract：AIMS:Obstructive sleep apnoea (OSA) is highly prevalent in patients with chronic heart failure (CHF) and may contribute to CHF progression. We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients...

journal_title：European heart journal

authors： Smith LA,Vennelle M,Gardner RS,McDonagh TA,Denvir MA,Douglas NJ,Newby DE

更新日期：2007-05-01 00:00:00

abstract：Aims:There are limited data on the clinical implications of total physiologic atherosclerotic burden assessed by invasive physiologic studies in patients with coronary artery disease. We investigated the prognostic implications of total physiologic atherosclerotic burden assessed by total sum of fractional flow reserve...

journal_title：European heart journal

authors： Lee JM,Koo BK,Shin ES,Nam CW,Doh JH,Hwang D,Park J,Kim KJ,Zhang J,Hu X,Wang J,Ahn C,Ye F,Chen S,Yang J,Chen J,Tanaka N,Yokoi H,Matsuo H,Takashima H,Shiono Y,Akasaka T

更新日期：2018-03-14 00:00:00

abstract：:The 18 month mortality rate in 2180 patients excluded from the Danish Verapamil Infarction Trail II (DAVIT II) was 25.6%. In non-consenters (n = 368) this was 15.0% compared with 13.85 in 897 placebo-treated patients (hazard ratio 1.09 [P = 0.60] when adjusting for sex and age). The increased mortality rate in exclude...

journal_title：European heart journal

authors： Madsen JK,Hansen JF

更新日期：1993-03-01 00:00:00

abstract：:The long-term efficacy of transdermal nitrate therapy, in particular the ability of a single patch to provide 24 h prophylaxis against angina, has been questioned. Two mechanisms have been suggested for this loss of effect: the development of pharmacological tolerance, and premature patch exhaustion. This study was de...

journal_title：European heart journal

authors： James MA,Papouchado M,Jones JV

更新日期：1991-12-01 00:00:00

abstract：:A 22-year-old man who engaged in intense and regular physical exercise complained of atypical chest pain. The only remarkable abnormality found in the routine clinical work-up was a left posterior hemiblock. The echocardiogram and the magnetic resonance imaging (MRI) study showed a tumour in the posterior and superior...

journal_title：European heart journal

authors： Cola H,Hoffman R,Borrega NG,Lazzari JO

更新日期：1992-04-01 00:00:00

abstract：AIMS:To identify variables predicting ejection fraction (EF) recovery and characterize prognosis of heart failure (HF) patients with EF recovery (HFrecEF). METHODS AND RESULTS:Retrospective study of adults referred for ≥2 echocardiograms separated by ≥6 months between 2008 and 2016 at the two largest echocardiography ...

journal_title：European heart journal

authors： Ghimire A,Fine N,Ezekowitz JA,Howlett J,Youngson E,McAlister FA

更新日期：2019-07-01 00:00:00

abstract：AIMS:To determine the potential adjunct of high-sensitivity (hs) C-reactive protein for risk stratification in patients with stable congestive heart failure (CHF). METHODS AND RESULTS:We studied 546 consecutive patients clinically stable with an ejection fraction <45% who were referred to our centre for evaluation of ...

journal_title：European heart journal

authors： Lamblin N,Mouquet F,Hennache B,Dagorn J,Susen S,Bauters C,de Groote P

更新日期：2005-11-01 00:00:00

abstract：:Aims Abciximab has previously been shown to enhance thrombolysis and improve myocardial perfusion when combined with reduced doses of alteplase. The purpose of the reteplase phase of TIMI 14 was to evaluate the effects of abciximab when used in combination with a reduced dose of reteplase for ST-elevation myocardial i...

journal_title：European heart journal

authors： Antman EM,Gibson CM,de Lemos JA,Giugliano RP,McCabe CH,Coussement P,Menown I,Nienaber CA,Rehders TC,Frey MJ,Van der Wieken R,Andresen D,Scherer J,Anderson K,Van de Werf F,Braunwald E

更新日期：2000-12-01 00:00:00

abstract：:The alterations of the beta-adrenoceptor adenylyl cyclase are reviewed. In failing myocardium, the down-regulation of beta 1-adrenoceptors is accompanied by a decrease in steady state mRNA levels, as studied with quantitative polymerase chain reactions in dilated and ischaemic cardiomyopathy. The density of beta 2-adr...

journal_title：European heart journal

authors： Böhm M,Lohse MJ

更新日期：1994-12-01 00:00:00

abstract：AIMS:The relative benefits of computed tomography coronary angiography (CTCA)-guided management in women and men with suspected angina due to coronary heart disease (CHD) are uncertain. METHODS AND RESULTS:In this post hoc analysis of an open-label parallel-group multicentre trial, we recruited 4146 patients referred ...

journal_title：European heart journal

authors： Mangion K,Adamson PD,Williams MC,Hunter A,Pawade T,Shah ASV,Lewis S,Boon NA,Flather M,Forbes J,McLean S,Roditi G,van Beek EJR,Timmis AD,Newby DE,McAllister DA,Berry C

更新日期：2020-04-01 00:00:00

abstract：:Large-scale randomized clinical trials have established the efficacy of cholesterol-lowering, blood pressure-lowering, and anti-platelet therapy to prevent cardiovascular diseases. A challenge for clinicians is to apply group-level evidence from these trials to individual patients. Trials typically report a single tre...

journal_title：European heart journal

authors： van der Leeuw J,Ridker PM,van der Graaf Y,Visseren FL

更新日期：2014-04-01 00:00:00

abstract：AIMS:Cardiomyopathy produces significant mortality in patients with Friedreich ataxia (FA), a genetic disorder that produces intra-mitochondrial iron accumulation. We sought to test the hypothesis that abnormal myocardial perfusion reserve and fibrosis represent early manifestations of cardiomyopathy. METHODS AND RESU...

journal_title：European heart journal

authors： Raman SV,Phatak K,Hoyle JC,Pennell ML,McCarthy B,Tran T,Prior TW,Olesik JW,Lutton A,Rankin C,Kissel JT,Al-Dahhak R

更新日期：2011-03-01 00:00:00

abstract：:Ten patients with chronic intermittent claudication were included in a double-blind, randomized cross-over study of placebo, propranolol 80 mg b.i.d. and metoprolol 100 mg b.i.d., each given for two months. At the end of each treatment period, the patients were tested on a treadmill and the time to first claudication ...

journal_title：European heart journal

authors： Bogaert MG,Clement DL

更新日期：1983-03-01 00:00:00

abstract：:Atrial fibrillation is a frequent cause of stroke; in the elderly, more than 20% of strokes are attributed to this common arrhythmia. Anticoagulation with warfarin reduces the risk of stroke by ∼60%; however, a large proportion of patients with atrial fibrillation do not receive this treatment because of relative/abso...

journal_title：European heart journal

authors： Landmesser U,Holmes DR Jr

更新日期：2012-03-01 00:00:00