Abstract:
:In the United States, co-administration of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine and tetravalent meningococcal conjugate vaccine (MCV4) is recommended in adolescents. In this clinical study, 1341 adolescents received Tdap (Boostrix® GlaxoSmithKline) and MCV4 (Menactra®, Sanofi-Pasteur) simultaneously or sequentially one month apart. Co-administration of Tdap+MCV4 was well tolerated and immunogenic, resulting in high levels of antibodies against diphtheria, tetanus, pertussis and meningococcal serogroup A,C,W-135 and Y antigens. The data provide support for current recommendations for co-administration of Tdap and MCV4 vaccines at the same office visit.
journal_name
Vaccinejournal_title
Vaccineauthors
Weston WM,Friedland LR,Wu X,Howe Bdoi
10.1016/j.vaccine.2010.11.057subject
Has Abstractpub_date
2011-01-29 00:00:00pages
1017-22issue
5eissn
0264-410Xissn
1873-2518pii
S0264-410X(10)01691-9journal_volume
29pub_type
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