Abstract:
:Hyponatremia is common and is increasingly recognized as an independent prognostic marker that adversely affects morbidity and mortality in various disease states, including heart failure. In acute decompensated heart failure (ADHF), the degree of hyponatremia often parallels the severity of cardiac dysfunction and is further exacerbated by any reduction in glomerular filtration rate and arginine vasopressin dysregulation. A recent study showed that even modest improvement of hyponatremia may have survival benefits. Although management of hyponatremia in ADHF has traditionally focused on improving cardiac function and fluid restriction, the magnitude of improvement of serum sodium is fairly slow and unpredictable. In this article, we discuss the mechanisms of hyponatremia in ADHF, review its evolving prognostic significance, and evaluate the efficacy of various treatments for hyponatremia, including the recently approved vasopressin receptor antagonists for managing hyponatremia among patients hospitalized for ADHF.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Jao GT,Chiong JRdoi
10.1002/clc.20822subject
Has Abstractpub_date
2010-11-01 00:00:00pages
666-71issue
11eissn
0160-9289issn
1932-8737journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND:The ventriculophasic response (VR) refers to shortening of atrial cycle length during heart block when a QRS complex is interposed between P waves. No formal quantitative definition has heretofore been proposed, nor have its potential clinical correlations been studied. HYPOTHESIS:We hypothesized that VR is...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20998
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Genetic influence on development of athlete's heart is uncertain. This study investigated whether angiotensin-converting enzyme (ACE) gene polymorphism influenced development of athlete's heart. METHODS:Forty-three participants in a 100-km ultramarathon were classified on the basis of ACE gen...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960230814
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Data are being accumulated on the presence of inflammatory response in patients with acute coronary syndromes. HYPOTHESIS:The study was undertaken to confirm that the adhesive state of the peripheral blood leukocytes can provide information on an inflammatory process in patients with unstable angina pectori...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201208
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:Current guidelines for the use of implantable cardioverter-defibrillators (ICDs) are broad and significantly increase the cost of caring for patients with heart failure. In an effort to identify the specific subset of patients who benefit from this therapy, the predictive value of numerous echocardiographic ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20474
更新日期:2009-12-01 00:00:00
abstract::In this report, a rare case of tricuspid stenosis uncomplicated by other valve lesions is presented, with clinical, hemodynamic, echocardiographic, and angiographic studies. The patient was markedly incapacitated, mostly as a result of a restricted cardiac output. Tricuspid commissurotomy was performed, with a stenoti...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960060406
更新日期:1983-04-01 00:00:00
abstract::A case of systemic hypotension with volume depletion not responding to intravenous fluids was found to have features of cardiac tamponade on two-dimensional (2-D) echocardiography. Intracardiac pressures were normal on cardiac catheterization. An interesting observation was the presence of left ventricular (LV) collap...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210318
更新日期:1998-03-01 00:00:00
abstract::Angioplasty in patients with unstable coronary artery disease is associated with higher complication rates compared with patients with stable disease. In this report we describe our results from a group of patients with unstable disease (unstable angina pectoris and postmyocardial infarction) where a strategy of delay...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190208
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:The implantable cardioverter defibrillator (ICD) is the most effective treatment available for terminating potentially life-threatening ventricular tachycardia and ventricular fibrillation and reducing the risk of mortality. Despite its established health benefits, ICD therapy is accompanied by a unique arra...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.20035
更新日期:2007-02-01 00:00:00
abstract::To analyze the paradox of acute myocardial infarction (AMI) with an initially normal electrocardiogram (ECG), we reviewed the records of 732 patients discharged with a final diagnosis of AMI over a 2-year period. Twenty-one patient were identified whose initial ECG was normal and who underwent coronary arteriography d...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960181006
更新日期:1995-10-01 00:00:00
abstract::His-bundle ablation is a very effective method to control drug-refractory supraventricular arrhythmias. We present a 69-year-old woman with paroxysmal atrial fibrillation, in whom several attempts of unipolar and bipolar His-bundle ablation were ineffective. Ultimately a stable 2/1 atrioventricular block was induced w...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100516
更新日期:1987-05-01 00:00:00
abstract::Embolism of a fragment of a central venous catheter is a serious clinical complication, especially when the fragment cannot be made visible by radiological methods. We report a case where such a fragment could only be localized by transesophageal echocardiography (TEE). With combined use of x-rays and TEE, the cathete...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960110614
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:Following successful cavotricuspid isthmus (CTI) ablation during typical atrial flutter (AFL), anticoagulation therapy is usually withdrawn. However, potential subsequent atrial fibrillation (AF) in these patients may increase embolic risk in the long term. Embolic rates in this setting have not been clearly...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22538
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Radiation-treated head and neck cancer (HNC) patients are at high risk for developing radiation vasculopathy, as evidenced by an increased stroke risk. The benefits of screening and assessing the cardiovascular (CV) risk of HNC patients using carotid intima-media thickness (CIMT) ultrasound are not known. Ou...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22389
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:One-third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics of responders to CRT have been studied in multiple clinical trials. HYPOTHESIS:Independent predictors of CRT response may be identified by studying a series of patients in routine clini...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22043
更新日期:2012-12-01 00:00:00
abstract::Cusp entrapment is a previously unreported mechanism of aortic insufficiency after balloon aortic valvuloplasty. In a patient who developed severe acute aortic insufficiency and expired after balloon aortic valvuloplasty, pathologic evaluation revealed a large, solitary, fractured, calcific nodule in the noncoronary c...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120711
更新日期:1989-07-01 00:00:00
abstract::The clinical impact of increasing levels of blood loss has been shown to increase morbidity and mortality after percutaneous coronary intervention (PCI). The impact of red blood cell (RBC) transfusion for severe bleeding is unknown. We systematically collected baseline and 8-h postprocedure hematocrit (HCT) values on ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20231
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Epicardial placement of the left ventricular (LV) lead via a video-assisted thoracoscopic (VAT) approach is an alternative to the standard transvenous technique. HYPOTHESIS:Long-term safety and efficacy of VAT and transvenous LV lead implantation are comparable. To test it, we reviewed our experience and we...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23300
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Japan is an aging society, and the number of nonagenarians with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) is increasing, but their outcomes have not been determined fully. METHODS:We prospectively enrolled 767 consecutive patients who underwent TAVI in t...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.23183
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The real-world impact of remote pulmonary artery pressure (PAP) monitoring on New York Heart Association (NYHA) class improvement and heart failure (HF) hospitalization rate is presented here from a single center. HYPOTHESIS:METHODS: Seventy-seven previously hospitalized outpatients with NYHA class III HF w...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22643
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Guidelines suggest that "upstream" P2Y12 receptor antagonists should be considered in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). HYPOTHESIS:Early use of ticagrelor in patients managed with an invasive strategy would be more effective than clopidogrel because of its more rapi...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.22733
更新日期:2017-06-01 00:00:00
abstract::Adenosine triphosphate (ATP) and adenosine exert strong and transient depressant effects on the sinoatrial and atrioventricular (AV) nodes of the human heart. The AV nodal effects of these drugs explain their high efficacy in either terminating AV re-entrant supraventricular tachycardia or in slowing ventricular rate ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960080903
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND:Recent data suggests that low molecular weight heparins (LMWHs) may be superior to unfractionated heparin (UFH) as an adjunct to fibrinolytic therapy in patients with acute ST-segment elevation myocardial infarction (STEMI). HYPOTHESIS:We evaluated cardiac outcomes and the risk of major bleeding with LMWHs ...
journal_title:Clinical cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/clc.20432
更新日期:2009-07-01 00:00:00
abstract::Various anatomical and functional features of hypertrophic cardiomyopathy are analyzed in view of the data provided by two-dimensional echocardiography. Measurement of septal thickness is crucial, and is best done by a combination of M-Mode and 2-D echo. Two types of systolic anterior movement of the mitral valve (SAM...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960071203
更新日期:1984-12-01 00:00:00
abstract:BACKGROUND:Heart failure is a significant cause of morbidity and mortality, yet patient risk stratification may be difficult. Prevention or treatment of atrial fibrillation (AF) may be an important strategy in these patients that could positively affect their outcome. It has been demonstrated that in patients with syst...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22736
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Acute changes in high-sensitivity troponin T (hs-TnT) are induced by myocardial ischemia during exercise stress testing, but there are no reports of pharmacological stress testing. HYPOTHESIS:The pattern of troponin release by myocardial ischemia-induced pharmacological stress testing differs according to t...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22392
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Disruption of the atherosclerotic plaque is a common feature of both acute coronary syndromes and balloon dilatation of coronary artery stenoses. HYPOTHESIS:The study was undertaken to evaluate whether the known association of cholesterol levels and acute coronary syndromes also exists for the occurrence of...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4950260708
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:An experimental study showed that nebivolol is an effective agent in contrast-induced nephropathy (CIN) prophylaxis. HYPOTHESIS:We hypothesized that prophylactic nebivolol use had protective effects on renal function in human beings subjected to iodinated contrast agent since it has vasodilatory effect and ...
journal_title:Clinical cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1002/clc.21013
更新日期:2012-04-01 00:00:00
abstract::Hyperkalemia was associated with complete heart block in one patient that resolved by first showing right anterior hemiblock). Then the right bundle branch block resolved, leaving the marked left axis deviation that was present before the hyperkalemic episode. Another patient with hyperkalemia had right bundle branch ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960040110
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:It is unclear whether more severe coronary atherosclerosis is a prerequisite to an initial acute coronary event in women vs men. HYPOTHESIS:Women may have more severe coronary atherosclerosis than men in patients with acute coronary event. METHODS:We used intravascular optical coherence tomography (OCT) to...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22825
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Therapeutic angiogenesis, if combined with primary percutaneous transluminal coronary angioplasty or stent placement, could improve the outcome of patients suffering from multifocal coronary disease. HYPOTHESIS:Because of the concern that angiogenic growth factors might promote restenosis, we studied the ef...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960250606
更新日期:2002-06-01 00:00:00