Abstract:
:Recently, renal angiomyoadenomatous tumor (RAT) has been identified. However, there are no descriptions about clear cell renal cell carcinoma (RCC) with focal RAT-like features. A 33-year-old Japanese man was found to have a tumor in the left kidney. Macroscopically, the tumor extended into the perinephric fat tissue, and the cut surface showed the yellowish color. The histologic examination of the tumor consisted of 2 components of clear cell RCC and RAT-like area. The RAT-like area showed the admixture of epithelial cells with basophilic or clear cytoplasm and stromal component containing leiomyomatous stroma, fine capillary network, and pericytic network. Immunohistochemically, epithelial neoplastic cells in RAT-like area were diffusely positive for CD10 and RCC Ma. G-band karyotype showed the structural abnormality of chromosome 3 and both components of clear cell RCC and RAT-like area revealed the identical VHL gene mutation. Finally, pathologists should pay attention to the presence of clear cell RCC focally resembling RAT.
journal_name
Ann Diagn Patholjournal_title
Annals of diagnostic pathologyauthors
Kuroda N,Hosokawa T,Michal M,Hes O,Sima R,Ohe C,Lee GHdoi
10.1016/j.anndiagpath.2010.03.003subject
Has Abstractpub_date
2011-06-01 00:00:00pages
202-6issue
3eissn
1092-9134issn
1532-8198pii
S1092-9134(10)00039-0journal_volume
15pub_type
杂志文章abstract::Primary neuroendocrine carcinoma of the skin is a relatively rare tumor that was first described by Cyril Toker in 1972. Since the seminal paper by Toker based on simple morphologic observations and detailed clinical correlation, our understanding of the clinical, morphological, and biological attributes of these lesi...
journal_title:Annals of diagnostic pathology
pub_type: 传,历史文章,杂志文章,评审
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
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pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2010.01.001
更新日期:2011-02-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2010.08.003
更新日期:2011-12-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2010.01.005
更新日期:2010-06-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2010.07.008
更新日期:2011-12-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1016/j.anndiagpath.2007.04.001
更新日期:2007-06-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2012.08.004
更新日期:2013-08-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1053/adpa.2000.17892
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pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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