Abstract：
:Whole-transcriptome analyses have established that the plant circadian clock regulates virtually every plant biological process and most prominently hormonal and stress response pathways. Systems biology efforts have successfully modeled the plant central clock machinery and an iterative process of model refinement and experimental validation has contributed significantly to the current view of the central clock machinery. The challenge now is to connect this central clock to the output pathways for understanding how the plant circadian clock contributes to plant growth and fitness in a changing environment. Undoubtedly, systems approaches will be needed to integrate and model the vastly increased volume of experimental data in order to extract meaningful biological information. Thus, we have entered an era of systems modeling, experimental testing, and refinement. This approach, coupled with advances from the genetic and biochemical analyses of clock function, is accelerating our progress towards a comprehensive understanding of the plant circadian clock network.
journal_name
Curr Opin Genet Devjournal_title
Current opinion in genetics & developmentauthors
McClung CR,Gutiérrez RAdoi
10.1016/j.gde.2010.08.010subject
Has Abstractpub_date
2010-12-01 00:00:00pages
588-98issue
6eissn
0959-437Xissn
1879-0380pii
S0959-437X(10)00154-1journal_volume
20pub_type
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：2018-08-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2013.10.010
更新日期：2014-02-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2011.04.008
更新日期：2011-08-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2013.10.007
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2007.12.008
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：1995-08-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：2010-08-01 00:00:00
abstract：:The largest subunit of eukaryotic RNA polymerase II has an unusual tandemly repeated heptapeptide sequence at its carboxyl terminus. The function of this evolutionarily conserved carboxy-terminal domain is unknown; however, new evidence links it to the formation of a large multi-component RNA polymerase II complex pos...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/0959-437x(95)80009-3
更新日期：1995-04-01 00:00:00
abstract：:The circadian clock of the cyanobacterium Synechococcus elongatus PCC 7942 is built on a three-protein central oscillator that can be reconstituted in vitro, a redox-sensitive input for synchronization with the environment, and a bacterial two-component signal transduction pathway for global transcriptional regulation...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2010.09.002
更新日期：2010-12-01 00:00:00
