Abstract：
OBJECTIVE:The aim of this retrospective clinical study was to evaluate clinical features, histopathology, treatment regimen, and follow-up in 95 patients with genital lichen planus. MATERIALS AND METHODS:We retrospectively analyzed data of 95 women diagnosed with genital lichen planus and visiting the vulvar clinic at Erasmus MC, Rotterdam, the Netherlands. RESULTS:All patients were symptomatic, most often complaining of vulvar soreness and burning (31.6%). Of all women, 34% had persistent symptoms for more than 5 years. On physical examination, 81.1% showed sharply demarcated erythematous lesions, usually located at the vestibule, and 56.8% had oral lesions. Treatment usually consisted of potent topical corticosteroids. Seventeen women (17.9%) were referred to the gynecology department for additional surgical treatment. In two of them, a vulvar squamous cell carcinoma was detected, followed by radical surgery. CONCLUSIONS:In cases with vulvar soreness and burning, sharply demarcated erythematous vulvar lesions, and the concomitant presence of oral lesions, the diagnosis of lichen planus should be considered and treatment must be initiated accordingly, even when histopathology is discordant.
journal_name
J Low Genit Tract Disjournal_title
Journal of lower genital tract diseaseauthors
Santegoets LA,Helmerhorst TJ,van der Meijden WIdoi
10.1097/LGT.0b013e3181d73622subject
Has Abstractpub_date
2010-10-01 00:00:00pages
323-8issue
4eissn
1089-2591issn
1526-0976pii
00128360-201010000-00009journal_volume
14pub_type
杂志文章abstract：OBJECTIVES:Our objective in this study was to evaluate the clinicopathological significance of tissue eosinophilia associated with invasive cervical carcinomas. MATERIALS AND METHODS:All cases of cervical carcinoma treated at the Medical College of Georgia between October 1982 and October 1989 were reviewed. We obtain...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1046/j.1526-0976.1999.34006.x
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:Chronic vulvar pruritus and vulvodynia are common vulvar diseases. The aim of this study was to compare gynecologic and sexual and physical abuse histories from patients with these diagnoses and from healthy controls. MATERIALS AND METHODS:Questionnaires were self-completed by patients diagnosed with vulvar ...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000075
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To determine if human papillomavirus (HPV) DNA in pelvic lymph nodes or plasma of women with early-stage cervical cancer is a marker for recurrence. MATERIALS AND METHODS:Twenty-eight women undergoing radical hysterectomy for cervical cancer stage IB had HPV DNA testing in cervical tissue, plasma, and the la...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e31818c66e6
更新日期：2009-04-01 00:00:00
abstract：:OBJECTIVES.: This study evaluates the long-term clinical success of Durasphere (Carbon Metal Technologies, St. Paul, MN) compared with Contigen (C. R. Bard, Covington, GA) in the treatment of stress urinary incontinence caused by intrinsic sphincter deficiency (ISD). METHODS.: Fifty-two women diagnosed with stress uri...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-200210000-00009
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:: This study aimed to explore the role of hormone replacement therapy (HRT) in susceptibility to vulvovaginal candidiasis (VVC) in a private vulval disease referral practice. METHODS:: Between January 2009 and December 2010, 149 healthy, nondiabetic patients with vulvar conditions were compared for significa...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e3182241f1a
更新日期：2011-10-01 00:00:00
abstract：:A 17-year-old adolescent girl developed severe toxic epidermal necrolysis after inhalation of methamphetamine. Recovery was complicated by vaginal synechiae and occlusion necessitating surgery. ...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e3181ddf5da
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Massive localized lymphedema (MLL) is a recently described entity associated with obesity, most often on the thighs. It rarely occurs on the vulva, and it may pose diagnostic difficulty for both clinician and pathologist in this setting. CASE:An obese 55-year-old woman underwent excision of bilateral polypo...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章,评审
doi：10.1097/LGT.0b013e31829cf432
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the ability of collecting the Affirm VP-III test sample using the residual vaginal discharge found on the speculum. METHODS AND METHODS:One hundred nine symptomatic women (≥18 y) participated in this study. During pelvic examination, vaginal fluid was collected onto 3 swabs for office-based diagn...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000025
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To compare rates of cervical intraepithelial neoplasia grade 3 or greater (CIN3+) between women aged 21 to 24 and women aged 25 or older undergoing a see-and-treat strategy for high-grade squamous intraepithelial lesion (HSIL) cytology. METHODS:In this retrospective cohort study, women treated with a see-and...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000229
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to describe temporal trends in screening and outcomes for women, after changes in guidelines in Alberta, Canada, that raised starting age to 21 years, then to 25 years of age, and reduced frequency to 3 yearly. MATERIALS AND METHODS:Calgary Laboratory Information System data were use...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000574
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVES:Vulvar vestibule is a common term in the medical nomenclature. In our view, this term is inaccurate. MATERIALS AND METHODS:Herein, we provide evidence from embryologic, anatomic, and architectonic textbooks that shows the links between the vestibule and vagina. RESULTS:Our research proves that the term vul...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-200401000-00014
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to assess the risk of progression/persistence of squamous intraepithelial lesions (SILs) during pregnancy according to the age of the woman, the grade of the lesion, the type of human papillomavirus (HPV) infection, and the mode of delivery. MATERIALS AND METHODS:Eighty pregnant women with a...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e31822e83cf
更新日期：2012-01-01 00:00:00
abstract：:To document the first reported synchronous occurrence of Hodgkin lymphoma and adenosquamous carcinoma involving the female genital tract. Review of cytologic, histologic, and immunohistochemical studies obtained from a 50-year-old, multiparous, postmenopausal, Hispanic female who had a left inguinal mass, bilateral lo...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-200310000-00015
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:To determine whether Hybrid Capture 2 High-Risk HPV DNA Test (HC2) can be used as a test of cure in women treated for cervical intraepithelial neoplasia grade 2 or worse (CIN 2+) and allow discharge from colposcopy follow-up with a return to a cytology-based screening program for HC2-negative women. MATERIA...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000349
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:Women living with HIV experience higher risk of cervical cancer, but screening rates in the United States are lower than recommended. The purpose of this study was to examine whether an intervention using self-sampling of cervicovaginal cells for human papillomavirus (HPV) with results counseling would increa...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章,随机对照试验
doi：10.1097/LGT.0000000000000195
更新日期：2016-04-01 00:00:00
abstract：:Disseminated tuberculosis involving the uterine cervix and central nervous system is described in a 26-year-old Native American female with new-onset seizures. Her presenting complaint was generalized seizures with associated weight loss, chronic cough, global headache, and malaise. Pelvic examination revealed an exop...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1046/j.1526-0976.1999.08099.x
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:To determine if sites selected for colposcopic biopsy and histologically proven cervical intraepithelial neoplasia are distributed randomly across the cervix. MATERIALS AND METHODS:Data were evaluated from all patients who visited the Walter Reed Army Medical Center Colposcopy Clinic during a 20-month period...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-200501000-00008
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:To compare the results of cold knife conization (CKC) and loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia to determine if excisional method has effects on pathologic interpretation. METHODS:Retrospective review of the perioperative medical records of patients who had a C...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e31817ff940
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:The aims of this study are to analyze a cohort of women with vulvovaginal symptoms and positive cultures for non-albicans Candida (NAC) to determine whether yeast was responsible for their symptoms and to evaluate the mycological effectiveness of various regimens. METHODS:This observational study was perfor...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000126
更新日期：2016-01-01 00:00:00
abstract：:OBJECTIVES.: To determine the prevalence of cervical dysplasia, diagnosed cytologically (squamous intraepithelial lesion [SIL]) or histologically (cervical intraepithelial neoplasia [CIN]), in women with external anogenital warts, and to determine the discriminating risk factors between those with and without cervical...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-200301000-00006
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To determine guidelines for management of CIN1 by evaluating its natural history. METHODS:One hundred fifty-eight patients were diagnosed with CIN1 had colposcopy follow-up with or without cytology every three months. RESULTS:Colposcopically directed biopsy confirmed progression to CIN2 or CIN3 in 17 of 158...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to identify the clinicopathologic features and treatment outcome of primary extramammary Paget disease of the vulva (EMPDV). MATERIALS AND METHODS:We performed a retrospective analysis of 14 patients who were treated at our center from April 1994 to November 2010. RESULTS:The mean ...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000063
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:For the 2019 ASCCP Risk-Based Management Consensus Guidelines, we conducted a systematic review of diagnostic assays for postcolposcopy and posttreatment management. MATERIALS AND METHODS:A literature search was conducted to identify articles reporting on tests/assays for cervical cancer screening, triage, p...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章,meta分析
doi：10.1097/LGT.0000000000000526
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE:The current study tested the hypothesis that collagen content in the pregnant cervix decreases with labor, using morphologically preserved specimens, avoiding limitations of earlier studies. Collagen abundance remote from pregnancy was also evaluated. MATERIALS AND METHODS:Histologic sections of postpartum c...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0b013e31822bb004
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to investigate the effects of 3 or less quadrivalent human papillomavirus (HPV) vaccine doses on anogenital warts in both males and females in the United States. MATERIALS AND METHODS:We conducted a retrospective database study that included males and females aged 9 to 26 years who r...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000401
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Pregnancy-related vulvar fibroadenoma of ectopic breast tissue is rare. Management involves diagnosing the mass as a fibroadenoma by physical examination and delaying excision until the postpartum period. CASE:A 31-year-old multigravid woman at 29 weeks' gestation had a right labial mass that was increasing...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/00128360-199707000-00035
更新日期：1997-07-01 00:00:00
abstract：OBJECTIVE:Obese women have higher cervical cancer incidence and mortality than their counterparts, possibly related to nonadherence to screening recommendations. We assessed the association of body mass index with adherence to cervical cancer screening recommendations in Hispanic women living in Puerto Rico, a minority...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章
doi：10.1097/LGT.0000000000000504
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:Bacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint of the patients. The numbe...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章,评审
doi：10.1097/LGT.0b013e31829156ec
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES OF THE STUDY:To systematically evaluate the literature regarding vulvodynia treatment outcome measures. METHODS:A systematic literature search on OVID, PubMed, and PsycINFO databases was conducted from inception until May 2016. Studies were included/excluded based on prespecified criteria. Reported outcome ...
journal_title：Journal of lower genital tract disease
pub_type： 杂志文章,评审
doi：10.1097/LGT.0000000000000406
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:We evaluated the performance of the Papanicolaou smear in screening and diagnostic settings. STUDY DESIGN:We analyzed Papanicolaou smear results of 1,850 women recruited into a clinical trial to evaluate an emerging technology for the detection of cervical cancer. Screening and diagnosis groups were based on...
journal_title：Journal of lower genital tract disease
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1097/LGT.0b013e31816b44bc
更新日期：2008-10-01 00:00:00
