Cord blood administration induces oligodendrocyte survival through alterations in gene expression.

abstract：:Electrode-implanted rats pressed a lever to self-stimulate a reward mechanism in their lateral hypothalamus (LH) each time with a brief train of pulses. Interdigitation of a medial hypothalamus (MH) train into the ipsilateral LH train inhibited the reward as indicated by a reduced lever pressing rate. Such interdigita...

journal_title：Brain research

authors： Porrino LJ,Coons EE,MacGregor B

更新日期：1983-10-31 00:00:00

abstract：:Our previous studies have shown that tumor necrosis factor-alpha (TNF-alpha) activates solitary nucleus neurons involved in vago-vagal reflex control of gastric motility. Here, we describe the dual role of TNF-alpha as also modulating neurons in the dorsal motor nucleus of the vagus (DMN) that respond to gastric diste...

journal_title：Brain research

authors： Emch GS,Hermann GE,Rogers RC

更新日期：2002-10-04 00:00:00

abstract：:Previous studies on the pathophysiology of white matter anoxic injury have revealed that the Na(+)-Ca2+ exchanger is an important mediator of Ca2+ overload. To date, however, the localization of this key Ca2+ transporter in myelinated axons has not been demonstrated. The present study uses immunofluorescence labeling ...

journal_title：Brain research

authors： Steffensen I,Waxman SG,Mills L,Stys PK

更新日期：1997-11-21 00:00:00

abstract：:We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phe...

journal_title：Brain research

authors： Oka K,Oka T,Hori T

更新日期：1997-08-29 00:00:00

abstract：:Subcommissural organ (SCO) is a highly specialized ependymal gland located in the roof of the third ventricle. The secretory products of the SCO, which condense to form Reissner's fiber (RF), were recently found to cross-react with the anti-calcitonin antibody. To understand the mechanisms regulating the formation of ...

journal_title：Brain research

authors： Saha SG,Jain MR,Subhedar N

更新日期：2000-01-10 00:00:00

abstract：:Partial sciatic nerve ligation in mice caused a marked and persistent decrease in the latency of paw withdrawal from a thermal stimulus only on the ipsilateral side. This thermal hyperalgesia was abolished by repeated intrathecal pretreatment with a specific antibody to brain-derived neurotrophic factor (BDNF), but no...

journal_title：Brain research

authors： Yajima Y,Narita M,Narita M,Matsumoto N,Suzuki T

更新日期：2002-12-27 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (kinase II) and protein phosphatase 2B (calcineurin) immunoreactivity in the rat hippocampus was studied 100 days after ischemic damage to hippocampal CA1 pyramidal neurons. One-hundred days after ischemia, only a few CA1 pyramidal neurons survived and they exhibited enha...

journal_title：Brain research

authors： Onodera H,Yamasaki Y,Kogure K,Miyamoto E

更新日期：1995-06-26 00:00:00

abstract：:We examined the expression of IL-6 in the substantia nigra pars reticulata (SNr) at various time points after transient (3 h) middle cerebral artery occlusion (MCAO) in rats. The animals were killed at 1, 3, 7 or 14 days following operation. Coronal brain sections were processed for immunohistochemistry with antibodie...

journal_title：Brain research

authors： Dihné M,Block F

更新日期：2001-01-19 00:00:00

abstract：:Previously we reported that several microRNAs (miRNA) are upregulated following experimentally induced traumatic brain injury (TBI) using both in vivo and in vitro approaches. Specific miRNAs were found to be sensitive to therapeutic hypothermia and may therefore be important targets for neuroprotective strategies. In...

journal_title：Brain research

authors： Truettner JS,Motti D,Dietrich WD

更新日期：2013-10-02 00:00:00

abstract：:We previously reported that reactive oxygen species (ROS) in paraventricular nucleus (PVN) modulated cardiac sympathetic afferent reflex (CSAR) and mediated the effect of angiotensin II (Ang II) in the PVN on the CSAR. In the present study, we investigated whether the NAD(P)H oxidase in the PVN was a key source of ROS...

journal_title：Brain research

authors： Zhang Y,Yu Y,Zhang F,Zhong MK,Shi Z,Gao XY,Wang W,Zhu GQ

更新日期：2006-04-12 00:00:00

abstract：:Ultrastructural examination of the region near the olfactory epithelial surface of leopard frogs revealed the presence of nerve terminals just proximal to the zonula adherens between adjacent sustentacular cells, and between sustentacular cells and olfactory receptor neurons. Terminal varicosities, located about 20 nm...

journal_title：Brain research

authors： Zielinski BS,Getchell ML,Getchell TV

更新日期：1989-07-17 00:00:00

abstract：:Administration of either Tyr-D-Ala-Gly-MePhe-Gly(ol) (DAGO), a mu-opioid agonist, or nicotine into the VTA (A10) caused an increase in both dopamine (DA) and its metabolite levels in both the A10 region and DA nerve terminals in the nucleus accumbens of rats when assessed with dual probe brain dialysis. These findings...

journal_title：Brain research

authors： Yoshida M,Yokoo H,Tanaka T,Mizoguchi K,Emoto H,Ishii H,Tanaka M

更新日期：1993-10-08 00:00:00

abstract：:Neurofibrillary tangles (NFTs) are a pathological hallmark of many neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP17). However, the cellular origin and the consequence of the NFT formation are poorly un...

journal_title：Brain research

authors： Wen Y,Yang S,Liu R,Simpkins JW

更新日期：2004-10-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) immunoreactivity in rat tissue was assayed using a new reversed-phase, ion-pair, high-pressure liquid chromatography (HPLC) method for separating TRH from its analogs. Virtually all of the TRH immunoreactivity in hypothalamus, brain stem, preoptic area, septum, striatum, frontal cor...

journal_title：Brain research

authors： Spindel E,Wurtman RJ

更新日期：1980-11-17 00:00:00

abstract：:Continuing from earlier work which demonstrated the peripheral axonal regulation of Schwann cell myelination, this study has investigated the possibility that a peripheral axon can stimulate oligodendrocyte myelination. To test this hypothesis, regenerating PNS axons were allowed to interact with uncommitted oligodend...

journal_title：Brain research

authors： Weinberg EL,Spencer PS

更新日期：1979-02-23 00:00:00

abstract：:Recent studies have demonstrated that sensory hair cells in the avian inner ear are reproduced by cell proliferation in response to the death of the original hair cell population. The regenerated hair cells appear to construct functional synaptic contacts, thereby transmitting acoustic signals to the peripheral nervou...

journal_title：Brain research

authors： Hashino E,Salvi RJ

更新日期：1996-05-13 00:00:00

abstract：PURPOSE:To determine whether antisense oligonucleotides (AODNs) targeted against CRX, a photoreceptor-specific trans-acting factor, suppress CRX expression and interphotoreceptor retinoid binding protein (IRBP) promoter activity. METHODS:Cultures of human retinoblastoma cells were transfected with chloramphenicol acet...

journal_title：Brain research

authors： Boatright JH,Borst DE,Stodulkova E,Nickerson JM

更新日期：2001-10-19 00:00:00

abstract：:Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regulation, and distribution of membrane-bound ion channels. Ion channels, ...

journal_title：Brain research

authors： Romer SH,Dominguez KM,Gelpi MW,Deardorff AS,Tracy RC,Fyffe RE

更新日期：2014-02-14 00:00:00

abstract：:Vestibular nerve branches innervating the sensory epithelia of the three semicircular canals or of the three otolith organs of frogs were selectively labeled in-vitro with biocytin. Labeled afferent fibers from the semicircular canals, utricle, and lagena were encountered in each of the four vestibular nuclei and thei...

journal_title：Brain research

authors： Birinyi A,Straka H,Matesz C,Dieringer N

更新日期：2001-12-07 00:00:00

abstract：:Dipiperidinoethane (DPE) administration produces seizures and CNS lesions. Here we elucidate the cholinergic origin of DPE toxicity. DPE is both an acetylcholinesterase (AChE) inhibitor and a muscarinic antagonist. This dual action negates most of the toxic effects of the compound in vivo. The neurotoxicity is believe...

journal_title：Brain research

authors： Baron BM,Kashman Y,Sokolovsky M

更新日期：1985-04-01 00:00:00

abstract：:We compared the laminar location and morphology of superior colliculus cells projecting to the dorsal and ventral lateral geniculate nuclei (LGd, LGv), the pretectum (PT), the parabigeminal nucleus (Pb), and nucleus lateralis posterior (LP) in the ground squirrel Spermophilus tridecemlineatus. Horseradish peroxidase w...

journal_title：Brain research

authors： Lugo-Garcia N,Kicliter E

更新日期：1987-11-17 00:00:00

abstract：:While adult mice receiving picrotoxin (PTX) alone responded with clonic and tonic-clonic seizures, this response was greatly suppressed for mice simultaneously injected with 2,3-butanedione monoxime (BDM). For example, 60% and 10% of the mice convulsed when injected (i.p.) with 3.0 mg/kg PTX alone or PTX plus 205 mg/k...

journal_title：Brain research

authors： Brightman T,Ye JH,Ortiz-Jimenez E,Flynn EJ,Wu WH,McArdle JJ

更新日期：1995-04-24 00:00:00

abstract：:Whilst the brain-specific benzodiazepine receptor has been assumed to show a late evolutionary appearance, we present evidence for the presence of a central benzodiazepine binding site in sharks, which shows a high affinity for [3H]Ro 15-1788. However, the receptor density and the affinities of several benzodiazepine ...

journal_title：Brain research

authors： Hebebrand J,Friedl W,Reichelt R,Schmitz E,Möller P,Propping P

更新日期：1988-04-19 00:00:00

abstract：:Water deprivation caused daily urinary Na output to more than double in normal sheep, but caused no increase in Na excretion in sheep (A3VL-sheep) in which the anterior third ventricle wall had been ablated. Dehydrated A3VL-sheep exhibited a much greater degree of hypernatremia than dehydrated normal sheep, although w...

journal_title：Brain research

authors： McKinley MJ,Denton DA,Park RG,Weisinger RS

更新日期：1983-03-21 00:00:00

abstract：:In vitro uptake of labeled serotonin (5-HT) has allowed the radioautographic detection of serotoninergic fibers in the cat spinal cord at thoracic and lumbar levels. The specificity of labeling was ensured by the conditions of incubation ([3H]5-HT was 10(-7) M) and by test control experiments with concomitant 10(-6) M...

journal_title：Brain research

authors： Segu L,Calas A

更新日期：1978-09-29 00:00:00

abstract：:Basic fibroblast growth factor (FGF-2) isoforms of the adrenal medulla are differentially expressed during rat postnatal development. While the 18 and 23 kDa isoforms continuously rise towards the adult expression level, the 21 kDa isoform displays a peak expression at postnatal day 28. The peak expression of the 21 k...

journal_title：Brain research

authors： Meisinger C,Grothe C

更新日期：1997-05-23 00:00:00

abstract：:Defeat stress in mice, a model of social stress, increases benzodiazepine receptor binding as measured by specific [3H]Ro15-1788 binding in vivo, but not by [3H]flunitrazepam binding in vitro. This increase occurs rapidly, by 20 min following exposure to stress, and resolves by 60 min. Increased benzodiazepine recepto...

journal_title：Brain research

authors： Miller LG,Thompson ML,Greenblatt DJ,Deutsch SI,Shader RI,Paul SM

更新日期：1987-06-30 00:00:00

abstract：:Tetanic stimulation of fibers in the hippocampal slice preparation produces long-term potentiation (LTP) and also decreases the in vitro incorporation of phosphate into the alpha subunit of pyruvate dehydrogenase (alpha PDH). This paper describes 6 experiments that were undertaken to replicate this observation. Hippoc...

journal_title：Brain research

authors： Hoch DB,Dingledine RJ,Wilson JE

更新日期：1984-06-04 00:00:00

abstract：:To assess the role of calcitonin gene-related peptide (CGRP) within the trigeminal subnucleus caudalis (Vc) on adrenal and autonomic function, microinjections were directed at different laminae of Vc in chloralose-anesthetized cats. Microinjections of CGRP (5 pmol, 100 nl) into laminae I-II increased significantly the...

journal_title：Brain research

authors： Bereiter DA,Benetti AP

更新日期：1991-08-30 00:00:00

abstract：:The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

journal_title：Brain research

authors： Fernandez-Tomé P,Segal M

更新日期：1987-09-01 00:00:00