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Long-term physical and neurologic development in newborn infants with isolated single umbilical artery.

Abstract：

OBJECTIVE:This study compared birth parameters and the longitudinal course in physical and neurologic development between children with 2 and 3 vessel umbilical cords. STUDY DESIGN:Our study of the Collaborative Perinatal Project included singletons of at least 24 weeks' gestation with single umbilical artery at birth and no identifiable congenital anomalies. Demographics that were collected included maternal age, race, smoking status, and socioeconomic index. Delivery data included gestational age, birthweight, Apgar scores, placental weight, and umbilical cord insertion and length. Growth and neurodevelopmental parameters were collected at various intervals from birth to 7 years. RESULTS:There were 263 infants with isolated single umbilical artery and 41,415 infants with 3 vessel cords. A random effect model that controlled for potential confounders did not show clinically significant differences in the physical and neurodevelopment measures between these groups. CONCLUSION:Our study shows no evidence of differential longitudinal physical growth or neurologic outcomes between infants with 2 or 3 vessel cords.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Chetty-John S,Zhang J,Chen Z,Albert P,Sun L,Klebanoff M,Grewal U

doi

10.1016/j.ajog.2010.06.031

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

368.e1-7

issue

4

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(10)00806-9

journal_volume

203

pub_type

杂志文章

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