Abstract:
:Mapping of 33 anonymous DNA probes and 12 genes to the long arm of chromosome 16 was achieved by the use of 14 mouse/human hybrid cell lines and the fragile site FRA16B. Two of the hybrid cell lines contained overlapping interstitial deletions in bands q21 and q22.1. The localization of the 12 genes has been refined. The breakpoints present in the hybrids, in conjunction with the fragile site, can potentially divide the long arm of chromosome 16 into 16 regions. However, this was reduced to 14 regions because in two instances there were no probes or genes that mapped between pairs of breakpoints.
journal_name
Genomicsjournal_title
Genomicsauthors
Chen LZ,Harris PC,Apostolou S,Baker E,Holman K,Lane SA,Nancarrow JK,Whitmore SA,Stallings RL,Hildebrand CEdoi
10.1016/0888-7543(91)90313-4subject
Has Abstract,Author List Incompletepub_date
1991-06-01 00:00:00pages
308-12issue
2eissn
0888-7543issn
1089-8646journal_volume
10pub_type
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