Adaptative response of nitrogen metabolism in early endotoxemia: role of ornithine aminotransferase.

abstract：:The effects of Red Bull Energy Drink, which includes taurine, glucuronolactone, and caffeine amongst the ingredients, were examined over 3 studies in a total of 36 volunteers. Assessments included psychomotor performance (reaction time, concentration, memory), subjective alertness and physical endurance. When compared...

journal_title：Amino acids

authors： Alford C,Cox H,Wescott R

更新日期：2001-01-01 00:00:00

abstract：:D-Asp-containing proteins have been implicated in many aging-related diseases. To clarify the role of D-Asp-containing proteins in such diseases, we developed a screening system for these proteins using a D-aspartyl endopeptidase that specifically cleaves the proteins at the C-terminus. The digested proteins were dete...

journal_title：Amino acids

authors： Sakai-Kato K,Kinouchi T,Fujii N,Imai K,Utsunomiya-Tate N

更新日期：2009-01-01 00:00:00

abstract：:The high efficiency of protein deposition during the neonatal period is driven by high rates of protein synthesis, which are maximally stimulated after feeding. In the current study, we examined the individual roles of amino acids and insulin in the regulation of protein synthesis in peripheral and visceral tissues of...

journal_title：Amino acids

authors： Suryawan A,O'Connor PM,Bush JA,Nguyen HV,Davis TA

更新日期：2009-05-01 00:00:00

abstract：:Contemporary theoretical models used in describing electrostatic properties of amino acids in polypeptides rely usually on atomic point charges. Recently noted defects of such models in reproducing protein folding originate from the inadequate representation of the electrostatic term, in particular inability of atomic...

journal_title：Amino acids

authors： Sokalski W

更新日期：1994-02-01 00:00:00

abstract：:We studied in vivo production of taurine, hypotaurine and sulfate following subcutaneous administration of L-cysteinesulfinate (CSA) to rats and mice. When 5.0 mmol/kg of body weight of CSA was injected to rats, increased urinary excretions of taurine, hypotaurine and sulfate in 24 h urine were 617, 52 and 1,767 micro...

journal_title：Amino acids

authors： Nakamura H,Yatsuki J,Ubuka T

更新日期：2006-07-01 00:00:00

abstract：:Hippocampus trimaculatus is one of the most heavily traded seahorse species for traditional medicine purposes in many countries. In the present study, we showed neuroprotective effects of peptide derived from H. trimaculatus against amyloid-β42 (Aβ42) toxicity which are central to the pathogenesis of Alzheimer's disea...

journal_title：Amino acids

authors： Pangestuti R,Ryu B,Himaya S,Kim SK

更新日期：2013-08-01 00:00:00

abstract：:The focus has been on the development of methodology for stereoselective preparation of spiroannulated intermediates of the Schöllkopf chiron and further transformations to cyclic alpha-amino acids. The spiroannulations are effected by Ru(II)-catalysed ring-closing metathesis reactions, by Ru(II)- and Pd(0)-catalysed ...

journal_title：Amino acids

authors： Undheim K

更新日期：2008-04-01 00:00:00

abstract：:Effects exerted by heavy isotope substitution in biopolymers on the functioning of whole organisms have not been investigated. We report on the decrease of permissive temperature of nematodes fed with bacteria containing 5,5-D2-lysine. We synthesized 5,5-dideuterolysine and, taking advantage of lysine being an essenti...

journal_title：Amino acids

authors： Korneenko TV,Pestov NB,Hurski AL,Fedarkevich AM,Shmanai VV,Brenna JT,Shchepinov MS

更新日期：2017-05-01 00:00:00

abstract：:The TES ether of the C6-hydroxy derivative of naturally occurring epi-jasmonic acid (epi-JA) was designed as epimerization-free equivalent of epi-JA. The TES ether was synthesized from (1R,4S)-4-hydroxycyclopent-2-enyl acetate in 13 steps. The acid part of the ether was activated with ClCO2Bui and subjected to condens...

journal_title：Amino acids

authors： Ogawa N,Kobayashi Y

更新日期：2012-05-01 00:00:00

abstract：:The reactions of phosphorus trichloride with various amino acids afford the pentacoordinated spirophosphoranes. The reaction procedures were traced by (31)P NMR spectra techniques. A new crystal structure of alanine derivative was characterized, which is a slightly distorted TBP structure. Besides, this kind of spirop...

journal_title：Amino acids

authors： Yu L,Liu Z,Fang H,Zeng QL,Zhao YF

更新日期：2005-06-01 00:00:00

abstract：:The increased protein requirement of endurance athletes may be related to the need to replace exercise-induced oxidative losses, especially of the branched-chain amino acids (BCAA). However, it is unknown if non-essential amino acids (NEAA) influence the requirement for essential amino acids (EAA) during post-exercise...

journal_title：Amino acids

authors： Kato H,Volterman KA,West DWD,Suzuki K,Moore DR

更新日期：2018-12-01 00:00:00

abstract：:Fibronectin (FN) is a cell adhesion protein that binds integrins in a process also involving the protein-crosslinking enzyme transglutaminase 2 (TG2) as a co-receptor. The cell-adhesive property of TG2 has been linked to a complex formation with FN and to its ability to crosslink and polymerize FN on the cell surface....

journal_title：Amino acids

authors： Forsprecher J,Wang Z,Nelea V,Kaartinen MT

更新日期：2009-04-01 00:00:00

abstract：:Minerals more readily adsorb amino acids with charged R groups than uncharged R groups, so that the incorporation of amino acids with charged R groups into peptides would be more frequent than for amino acids with uncharged R groups. However, 74% of the amino acids in the proteins of modern organisms contain uncharged...

journal_title：Amino acids

authors： Zaia DA

更新日期：2004-08-01 00:00:00

abstract：:Rats were trained to perform a conditioned avoidance response to white noise in a conventional two-compartment "shuttle-box". The partition between the compartments had two openings, however, and the correct passage (leftor right) was signalled by changes in background illumination. In this situation the psychotomimet...

journal_title：Amino acids

authors： Ahlenius S,Ericson E,Svensson TH

更新日期：1992-02-01 00:00:00

abstract：:This paper analyses the presence of and changes in free amino acids and biogenic amines in red and white muscle of bigeye tuna during storage in controlled atmospheres with 2 gas mixes containing different concentrations of CO(2) and O(2). Levels of amines were generally higher in white than in red muscle, with the ex...

journal_title：Amino acids

authors： Ruiz-Capillas C,Moral A

更新日期：2004-03-01 00:00:00

abstract：:Increased intracellular cysteine poses a potential danger to cells due to the high ability of cysteine to reduce free iron and promote the Fenton reaction. Here, we studied ways to maintain cysteine homeostasis in E. coli cells while inhibiting protein synthesis with valine or chloramphenicol. When growing wild-type b...

journal_title：Amino acids

authors： Smirnova GV,Tyulenev AV,Bezmaternykh KV,Muzyka NG,Ushakov VY,Oktyabrsky ON

更新日期：2019-11-01 00:00:00

abstract：:Isolated hepatocytes from rat liver in primary culture rapidly lost viability under hypoxic conditions. In the presence of glycine, L-alanine or L-serine loss of viability under hypoxic conditions was greatly retarded. Glycine and L-serine already showed significant protection from hypoxic injury at a concentration of...

journal_title：Amino acids

authors： Brecht M,de Groot H

更新日期：1994-02-01 00:00:00

abstract：:A novel recombinant disintegrin, vicrostatin (VCN), displays high binding affinity to a broad range of human integrins in substantial competitive biological advantage over other integrin-based antagonists. In this study, we synthesized a new 64Cu-labeled VCN probe and evaluated its imaging properties for prostate canc...

journal_title：Amino acids

authors： Jadvar H,Chen K,Park R,Yap LP,Vorobyova I,Swenson S,Markland FS

更新日期：2019-11-01 00:00:00

abstract：:In this review, recent studies on the electrophysiological effects of de novo synthesized ("endogenous") kynurenic acid (KYNA) are discussed. Endogenous KYNA is normally formed as a byproduct of tryptophan metabolism. Evidence for a physiological role in neuronal excitability has not been strong, in part because brain...

journal_title：Amino acids

authors： Scharfman HE,Goodman JH,Schwarcz R

更新日期：2000-01-01 00:00:00

abstract：:Asymmetric dimethylarginine (ADMA) is a methylated form of arginine and an endogenous nitric oxide synthase inhibitor. Renal function decline is associated with increase of plasma ADMA in chronic kidney disease populations. It is yet unknown how isolated renal function impairment affects ADMA homeostasis in healthy hu...

journal_title：Amino acids

authors： Said MY,Douwes RM,van Londen M,Minović I,Frenay AR,de Borst MH,van den Berg E,Heiner-Fokkema MR,Kayacelebi AA,Bollenbach A,van Goor H,Navis G,Tsikas D,Bakker SJL

更新日期：2019-03-01 00:00:00

abstract：:Recently, we observed that central administration of L-arginine attenuated stress responses in neonatal chicks, but the contribution of nitric oxide (NO) to this response was minimal. The sedative and hypnotic effects of L-arginine may be due to L-arginine itself and/or its metabolites, excluding NO. To clarify the me...

journal_title：Amino acids

authors： Suenaga R,Yamane H,Tomonaga S,Asechi M,Adachi N,Tsuneyoshi Y,Kurauchi I,Sato H,Denbow DM,Furuse M

更新日期：2008-06-01 00:00:00

abstract：:S-adenosylmethionine (SAM), a major substrate in 1-C metabolism is a common precursor in the biosynthetic pathways of polyamines and ethylene, two important plant growth regulators, which exhibit opposing developmental effects, especially during fruit ripening. However, the flux of various substrates including SAM int...

journal_title：Amino acids

authors： Lasanajak Y,Minocha R,Minocha SC,Goyal R,Fatima T,Handa AK,Mattoo AK

更新日期：2014-03-01 00:00:00

abstract：:L-tryptophan is an essential amino acid in food, but is also widely used as a drug on the basis of several physiological actions. Lately, tryptophan's uses as a drug and as a food supplement have been discontinued in several countries due to its severe side-effects.In the present study, the distribution of tryptophan ...

journal_title：Amino acids

authors： Sainio EL,Närvänen S,Sainio P,Tuohimaa P

更新日期：1995-06-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) constitute a diverse class of naturally occurring or synthetic antimicrobial molecules that have potential for use in the treatment of drug-resistant infections. Several undesirable properties of AMPs, however, may ultimately hinder their development as antimicrobial agents. Thus, new syn...

journal_title：Amino acids

authors： Dong N,Zhu X,Lv YF,Ma QQ,Jiang JG,Shan AS

更新日期：2014-09-01 00:00:00

abstract：:Emerging evidence from laboratory researches has highlighted the bioactivity of food melanoidins and melanoproteins. Whilst such studies have been carried out with different in vitro systems, information about melanoidins absorption and bio-availability are scarce. However, they are generally considered as poorly abso...

journal_title：Amino acids

authors： Tagliazucchi D,Bellesia A

更新日期：2015-06-01 00:00:00

abstract：:The daily requirement of a 70-kg male for creatine is about 2 g; up to half of this may be obtained from a typical omnivorous diet, with the remainder being synthesized in the body Creatine is a carninutrient, which means that it is only available to adults via animal foodstuffs, principally skeletal muscle, or via su...

journal_title：Amino acids

authors： Brosnan ME,Brosnan JT

更新日期：2016-08-01 00:00:00

abstract：:The aim of our research was to analyze the antioxidant role and efficacy of thermal or salus per aquam (spa) therapy with chlorine-sulphur-bicarbonate mineral water. The study has been performed on 30 rats. The animals were randomized in three groups, each of them composed by ten animals, denominated A, B and C. The A...

journal_title：Amino acids

authors： Costantino M,Giuberti G,Caraglia M,Lombardi A,Misso G,Abbruzzese A,Ciani F,Lampa E

更新日期：2009-02-01 00:00:00

abstract：:The effect of dietary amino acid taurine on the liver function of chronic hepatitis patients was investigated. The 24 chronic hepatitis patients with 2-5 times over normal activities of alanine aminotransferase (ALT) or aspartate aminotransferase (AST) were selected and equally divided into taurine treatment and contr...

journal_title：Amino acids

authors： Hu YH,Lin CL,Huang YW,Liu PE,Hwang DF

更新日期：2008-08-01 00:00:00

abstract：:In living cells, the N-terminal tails of core histones, the proteinaceous component of nucleosomes, are subjected to a range of covalent post-translational modifications (PTMs), which have specific roles in modulating chromatin structure and function. A growing body of evidence suggests that deregulation of histone mo...

journal_title：Amino acids

authors： Cuomo A,Moretti S,Minucci S,Bonaldi T

更新日期：2011-07-01 00:00:00

abstract：:Developmental changes in the levels of the excitatory amino acids L-glutamate (Glu) and L-Aspartate (Asp) and inhibitory amino acids glycine (Gly) and gamma-amino butyric acid (GABA), as well as taurine and its related amino acids L-methionine (Met), L-cysteine (Cys) and L-serine (Ser) in the brain and pectoralis musc...

journal_title：Amino acids

authors： Sato M,Tomonaga S,Denbow DM,Furuse M

更新日期：2009-02-01 00:00:00