Abstract:
:This study examined whether the number of psychotropic medications an individual is taking across classes influences side effects among adults with Intellectual Disability (ID). Participants were 80 adults diagnosed with ID. Dependent variables were the composite score and domain scores of the Matson Evaluation of Drug Side-effects (MEDS), which is an instrument used to assess side effects. There were three levels of the independent variable: Group 1--those taking zero psychotropic medications, Group 2--those taking one psychotropic medication, and Group 3--those taking two psychotropic medications across different medication classes. There was a significant main effect regarding number of psychotropic medication classes prescribed. Further analysis revealed that four of the nine MEDS domains had significantly different mean scores for number of psychotropic medication classes. For the majority of MEDS domains, such as Central Nervous System-General, Parkinsonism/Dyskinesia, and Behavioral/Akathesia domains, participants in the no psychotropic medication group had significantly lower mean scores than those in the one and two psychotropic medication groups. Only two MEDS domains, Cardiovascular and Hematologic Effects as well as Skin, Allergies, and Temperature, were significantly different between participants taking one psychotropic medication as compared with two psychotropic medications from different classes. Implications of these findings and recommendations for future research are discussed.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Mahan S,Holloway J,Bamburg JW,Hess JA,Fodstad JC,Matson JLdoi
10.1016/j.ridd.2010.05.006subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1561-9issue
6eissn
0891-4222issn
1873-3379pii
S0891-4222(10)00119-8journal_volume
31pub_type
杂志文章,多中心研究abstract::This study investigates how adults in two contrasting cultures (Italian and Japanese) perceive episodes of crying of typically developing (TD) children and children with Autism Disorder (AD). Although cries of children with AD have been reported to elicit more distress in Western cultures, it is not known whether simi...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.01.014
更新日期:2012-07-01 00:00:00
abstract::The purpose of this study was to investigate the resilience displayed by families raising children with disabilities and behavior problems. The question is why do some families do well when others, exposed to similar stressors, struggle to keep their family life running? A stratified (by child age group) random sample...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.01.015
更新日期:2014-04-01 00:00:00
abstract::This study explored self concepts in matched groups of adolescents and adults with Williams syndrome (WS) and Prader-Willi syndrome (PWS), using Damon and Hart's semi-structured interview. The main findings were that the WS participants were more productive in their responses to the interview, providing more self char...
journal_title:Research in developmental disabilities
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ridd.2003.05.003
更新日期:2004-03-01 00:00:00
abstract::Difficulties with handwriting are reported as one of the main reasons for the referral of children with Developmental Coordination Disorder (DCD) to healthcare professionals. In a recent study we found that children with DCD produced less text than their typically developing (TD) peers and paused for 60% of a free-wri...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.07.033
更新日期:2014-11-01 00:00:00
abstract::The present study sought to examine the longitudinal psychoeducational, neurocognitive, and psychiatric outcomes of children and adolescents with chromosome 22q11.2 deletion syndrome (22q11DS), a population with a high incidence of major psychiatric illnesses appearing in late adolescence/early adulthood. Little is kn...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.12.003
更新日期:2013-05-01 00:00:00
abstract::Recent studies show varying results on whether motor imagery capacity is compromised in individuals with cerebral palsy (CP). Motor imagery studies in children predominantly used the implicit hand laterality task. In this task participants judge the laterality of displayed hand stimuli. A more explicit way of studying...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.08.044
更新日期:2013-11-01 00:00:00
abstract::The current study examined the use of an instrument designed to evaluate the intrusiveness of treatments for addressing problem behaviors. Participants read case vignettes with proposed treatments and then completed a checklist of factors that could influence the degree of treatment intrusiveness. Results indicated th...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2007.11.002
更新日期:2009-01-01 00:00:00
abstract::Sleep EEG alterations are emerging features of several developmental disabilities, but detailed quantitative EEG data on the sleep phenotype of patients with Williams syndrome (WS, 7q11.23 microdeletion) is still lacking. Based on laboratory (Study I) and home sleep records (Study II) here we report WS-related feature...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2011.09.004
更新日期:2012-01-01 00:00:00
abstract::The aim of the study was to prospectively assess the differences in participation and sensory modulation between late preterm infants (LPI) and term babies, and to predict it by LPI characteristics. The study population includes 124 late preterm infants at gestational age between 34 and 35 6/7 weeks who were born at t...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2011.05.037
更新日期:2011-11-01 00:00:00
abstract::The purpose of this study was to investigate the effect of five variations of imagery and physical practice on learning of Basketball free throws in adolescents with mental retardation (AWMR). Forty AWMR were randomly assigned to five groups and performed a variation of practice: physical practice, mental practice, ph...
journal_title:Research in developmental disabilities
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ridd.2009.07.022
更新日期:2010-01-01 00:00:00
abstract::Developmental coordination disorder (DCD) as well as overweight and obesity are of increasing importance in the study of human development. Data on the relation between DCD and obesity in adolescence are of particular interest because both phenomena are unlikely to disappear with age. The objective of this study was t...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2011.04.004
更新日期:2011-09-01 00:00:00
abstract::The latest researchers have employed software technology to turn gyration air mice into a high performance limb detector to detect specific limb movement, and to further collaborate using the preferred environmental stimulation to help people with disabilities to suppress unwanted behaviors or habits and to reward goo...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.09.001
更新日期:2013-12-01 00:00:00
abstract::This study examined the relation between emergent literacy skills, teachers' reports of behavioral problems, and word reading achievement in a community sample of French students. Family background was investigated and included familial antecedents of reading difficulties (Fa/Rd) and parents' educational level. The an...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.11.029
更新日期:2013-03-01 00:00:00
abstract::The main goal of the study was to map the difficulties and cognitive processes among adolescents (aged 13-21, N = 30) and adults (aged 25-66, N = 30) with mild and moderate intellectual disability (ID) when solving analogical problems. The participants were administered the Conceptual and Perceptual Analogical Modifia...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2010.10.010
更新日期:2011-01-01 00:00:00
abstract::It is widely acknowledged that people with Down syndrome (Ds) have less highly developed morphosyntactic abilities than typically developing (TD) children. However, little is known about the morphological processing of this population. In this paper we carry out two experiments in which the morphological Base Frequenc...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.03.027
更新日期:2013-07-01 00:00:00
abstract::Functional assessment is a method to identify the relationships between a behavior of interest and an individual's environment. Traditional methods for functional assessment have relied on experimental techniques in which analog sessions are designed to replicate conditions in the individual's environment. However, th...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(00)00036-6
更新日期:2000-05-01 00:00:00
abstract::Many studies reported that adolescents with ADHD/RD more frequently engage in risk-taking behaviors. Very few have examined their risk taking patterns and the impact of their comorbidity. The present study compared the risk-taking propensity, sensitivity to punishment and delinquency outcome in Chinese adolescents wit...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2016.02.017
更新日期:2016-06-01 00:00:00
abstract::Evidence on the association between somatic chronic diseases in ID-adolescents and the full range of pervasive developmental disorder behavior (PDD behavior) is scarce. The aim of the present study is to assess the association between somatic chronic diseases in ID-adolescents and mild PDD behavior. We obtained data o...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2009.10.018
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Individuals with FASD experience neurodevelopmental impairments and adverse outcomes, which can result in stress on the caregiver. However, there is little research on the needs of caregivers supporting individuals with FASD and whether they are associated with caregiver stress. METHOD:125 caregivers of indi...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2016.03.002
更新日期:2016-08-01 00:00:00
abstract::Despite increasing attention to psychiatric disorders in the mentally retarded, suicidal behavior remains an underreported phenomenon in this population, particularly in children and adolescents. This study was aimed at documenting the existence of suicidal behavior among 90 consecutive admissions to a specialty unit ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/0891-4222(94)00029-8
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:U.S. adults with intellectual and developmental disabilities (IDD) have poorer health status and greater risks for being overweight and obese, which are major drivers of health care expenditures in the general population. Health care expenditures and IDD have not been studied using nationally representative ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2018.01.011
更新日期:2018-04-01 00:00:00
abstract::Children with Down syndrome (DS) display less stable and coordinated gait patterns in the time domain than their healthy peers. However, little is known about whether this group difference exists in the frequency domain. The purpose of this study was to investigate differences in vertical ground reaction force (GRF) i...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.03.019
更新日期:2014-06-01 00:00:00
abstract::Raising a child with Down syndrome (DS) has been found to be associated with lowered health related quality of life (HRQoL) in the domains cognitive functioning, social functioning, daily activities and vitality. We aimed to explore which socio-demographics, child functioning and psychosocial variables were related to...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.09.011
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The present study focused on typically developing siblings (TDS) in emerging adulthood of individuals with autism spectrum disorder (ASD) and sought insight into how gender may interact with positive and negative affects in this population. In addition, we aimed to explore the gender differences as a moderat...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2020.103829
更新日期:2021-01-01 00:00:00
abstract::A morphing procedure has been designed to compare directly the perception of emotional expressions and of moving objects. Morphing tasks were presented to 12 low-functioning teenagers with Autism Spectrum Disorder (LF ASD) compared to 12 developmental age-matched typical children and a group presenting ceiling perform...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2015.09.025
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Like any child, children with Down syndrome (DS) affect the lives of their families. Most studies focus on the adaptation of parents and families of young children with DS, while relatively few studies include the perspective of fathers. AIMS:To determine 1) whether mothers and fathers of 11 to 13-year-olds...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2016.09.014
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Research evidence from studies in North America on the relationships between family-centered practices, parents' self-efficacy beliefs, parenting confidence and competence beliefs, and parents' psychological well-being was used to confirm or disconfirm the same relationships in two studies in Spain. AIMS:Th...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2019.103495
更新日期:2019-11-01 00:00:00
abstract::Stereotypic behavior is one of the more common disturbed behaviors displayed by people who are developmentally disabled. This study evaluated the indirect effects on stereotypic frequency when the value of a concurrent fixed-interval reinforcement schedule for adaptive behavior was varied. Three profoundly mentally re...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/0891-4222(88)90033-9
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:There is conflicting evidence as to whether receptive language abilities of individuals with Down syndrome (DS) continue to improve into adulthood, reach a plateau in late adolescence, or even start to decline. AIM:The study aims to shed light on the question whether receptive syntactic skills change from c...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2017.01.014
更新日期:2017-03-01 00:00:00
abstract::Individuals with the neurodevelopmental disorder Williams syndrome (WS) often report difficulty processing and acting in depth, such as crossing roads or reaching for objects; however little research attention has been directed at understanding depth perception and action in depth in WS and whether deficits in depth p...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.04.013
更新日期:2014-08-01 00:00:00