Blood pressure and cardiovascular risk: what about cocoa and chocolate?

abstract：:The absorption spectra of Ni(II) bound to the core histone tetramer, (H3-H4)2, of chicken erythrocytes in 500 mM NaCl + 100 mM phosphate (pH 7.4) were recorded. A charge transfer band was seen at 317 nm, characteristic of a bond between Ni(II) and the sulfur atom of Cys-110 of histone H3. The conditional affinity cons...

journal_title：Archives of biochemistry and biophysics

authors： Bal W,Karantza V,Moudrianakis EN,Kasprzak KS

更新日期：1999-04-15 00:00:00

abstract：:Plumbagin (PLB), a natural naphthoquinone from the traditional folk medicines Plumbago zeylanica, Dionaea muscipula, or Nepenthes gracilis, has been documented possessing a wide variety of pharmacological activities. Although PLB demonstrates anticancer activity in multiple types of malignant cells, the cellular targe...

journal_title：Archives of biochemistry and biophysics

authors： Zhang J,Peng S,Li X,Liu R,Han X,Fang J

更新日期：2017-04-01 00:00:00

abstract：:Ultradian clock-coupled respiratory oscillation (UCRO) in an aerobic continuous culture of Saccharomyces cerevisiae S288C is principally regulated by control of certain redox reactions of energy metabolism. It is also modulated by the metabolism of storage carbohydrates during adaptation to environmental change. Howev...

journal_title：Archives of biochemistry and biophysics

authors： Ouyang Y,Xu Q,Mitsui K,Motizuki M,Xu Z

更新日期：2011-05-01 00:00:00

abstract：:Prostasomes are membranous vesicles (150-200 nm diameter) present in human semen. They are secreted by the prostate gland and contain large amounts of cholesterol, sphingomyelin, and Ca2+. In addition, some of their proteins are enzymes. Prostasomes enhance the motility of ejaculated sperm and are involved in a number...

journal_title：Archives of biochemistry and biophysics

authors： Carlini E,Palmerini CA,Cosmi EV,Arienti G

更新日期：1997-07-01 00:00:00

abstract：:The aim of the present study was to further understand how changes in membrane organization can lead to higher rates of lipid oxidation. We previously demonstrated that Al(3+), Sc(3+), Ga(3+), Be(2+), Y(3+), and La(3+) promote lipid packing and lateral phase separation. Using the probe Laurdan, we evaluated in liposom...

journal_title：Archives of biochemistry and biophysics

authors： Verstraeten SV,Oteiza PI

更新日期：2000-03-15 00:00:00

abstract：:To elucidate the physiological significance of ketone bodies on insulin and glucagon secretion, the direct effects of beta-hydroxybutyrate (BOHB) and acetoacetate (AcAc) infusion on insulin and glucagon release from perfused rat pancreas were investigated. The BOHB or AcAc was administered at concentrations of 10, 1, ...

journal_title：Archives of biochemistry and biophysics

authors： Ikeda T,Yoshida T,Ito Y,Murakami I,Mokuda O,Tominaga M,Mashiba H

更新日期：1987-08-15 00:00:00

abstract：:Flavopiridol has been shown to induce cell cycle arrest and apoptosis in various tumor cells in vitro and in vivo. Using immobilized flavopiridol, we identified glycogen phosphorylases (GP) from liver and brain as flavopiridol binding proteins from HeLa cell extract. Purified rabbit muscle GP also bound to the flavopi...

journal_title：Archives of biochemistry and biophysics

authors： Kaiser A,Nishi K,Gorin FA,Walsh DA,Bradbury EM,Schnier JB

更新日期：2001-02-15 00:00:00

abstract：:Advancements in peptide fusion technologies to maximize the protein production has taken a big leap to fulfill the demands of post-genomics era targeting elucidation of structure/function of the proteome and its therapeutic applications, by over-expression in heterologous expression systems. Despite being most preferr...

journal_title：Archives of biochemistry and biophysics

authors： Yadav DK,Yadav N,Yadav S,Haque S,Tuteja N

更新日期：2016-12-15 00:00:00

abstract：:The G1 glycoprotein of Punta Toro virus, a member of the bunyavirus family, accumulates in the Golgi complex when it is expressed from cloned cDNA. We previously reported that the information necessary for Golgi retention of the G1 protein is located within the transmembrane domain and a portion of the cytoplasmic dom...

journal_title：Archives of biochemistry and biophysics

authors： Matsuoka Y,Chen SY,Holland CE,Compans RW

更新日期：1996-12-01 00:00:00

abstract：:The stoichiometry of complex formation between two lysosomal proteinases from rabbit liver, cathepsin M and fructose 1,6-bisphosphatase converting enzyme (CE), and their respective endogenous inhibitors was studied by the equilibrium gel penetration method. In each case the molecular weight of the complex was found to...

journal_title：Archives of biochemistry and biophysics

authors： Pontremoli S,Melloni E,Salamino F,Sparatore B,Michetti M,Horecker BL

更新日期：1984-02-01 00:00:00

abstract：:An intermediate state of lentil lectin was characterized at pH 1 having low content of secondary as well as tertiary structure. Far- and near-UV CD spectroscopy showed loss of structure when pH was lowered from 7 to 0.8 but the structure loss was less than that of the protein in presence of 6M GndHCl. Intrinsic trypto...

journal_title：Archives of biochemistry and biophysics

authors： Naseem F,Khan RH

更新日期：2004-11-15 00:00:00

abstract：:Novel vitamin D3 derivatives, 26-homo-delta 22-1 alpha,25(S)-dihydroxyvitamin D3 and 26-homo-delta 22-1 alpha,25(R)-dihydroxyvitamin D3 were compared with the native hormone, 1,25-dihydroxyvitamin D3, and with other vitamin D3 derivatives, in inhibition of cell growth, induction of phenotypic differentiation, and c-my...

journal_title：Archives of biochemistry and biophysics

authors： Koizumi T,Nakao Y,Ishizuka S,Oshida J,Hara N,Ikekawa N,Fijita T

更新日期：1990-02-01 00:00:00

abstract：:Heavy-atom isotope effects for the N-demethylation of nicotine have been determined in vivo in static-phase biosynthetically incompetent plant cell cultures of Nicotiana species. A (2)H kinetic isotope effect of 0.587 and a (15)N kinetic isotope effect of 1.0028 were obtained. An identical (15)N kinetic isotope effect...

journal_title：Archives of biochemistry and biophysics

authors： Molinié R,Kwiecień RA,Paneth P,Hatton W,Lebreton J,Robins RJ

更新日期：2007-02-15 00:00:00

abstract：:The cellular environment is crowded with different kinds of molecules with varying sizes, shapes and compositions. Most of the experiments studying the nature and behaviour of a protein have been done on the isolated protein in dilute buffer solutions which actually do not imitate the in vivo situation. To understand ...

journal_title：Archives of biochemistry and biophysics

authors： Shahid S,Ahmad F,Hassan MI,Islam A

更新日期：2015-10-15 00:00:00

abstract：:Vanadate-dependent oxidation of NADH by xanthine oxidase does not require the presence of xanthine and therefore is not due to cooxidation. Addition of NADH or xanthine had no effect on the oxidation of the other substrate. Oxidation of NADH was high at acid pH and oxidation of xanthine was high at alkaline pH. The sp...

journal_title：Archives of biochemistry and biophysics

authors： Khandke L,Gullapalli S,Patole MS,Ramasarma T

更新日期：1986-02-01 00:00:00

abstract：:Isolated mitochondria loaded with Ca(2+) and then exposed to Fe(2+) show a transient release of Ca(2+). The magnitude of this response depends on the Ca(2+) loading and the kinetics of the response depends on the concentration of added Fe(2+). We investigated the Fe(2+)-induced Ca(2+) release mechanism by measuring mi...

journal_title：Archives of biochemistry and biophysics

authors： Gogvadze V,Walter PB,Ames BN

更新日期：2002-02-15 00:00:00

abstract：:The flavoprotein monoamine oxidase B (MAO B) from bovine liver, as isolated, has an unusual additional absorption band at 412 nm, which is similar to the absorption of its anionic flavin semiquinone form, (Fl.-), and other typical (Fl.-) flavoproteins. Denaturation of the enzyme results in the elimination of this anom...

journal_title：Archives of biochemistry and biophysics

authors： Yue KT,Bhattacharyya AK,Zhelyaskov VR,Edmondson DE

更新日期：1993-01-01 00:00:00

abstract：:In a precedent report we showed that alpha-bisabolol, a sesquiterpene present widely in the plant kingdom, exerts a rapid and efficient apoptosis-inducing action selectively towards human and murine malignant glioblastoma cell lines through mitochondrial damage. The present study extends these data demonstrating the a...

journal_title：Archives of biochemistry and biophysics

authors： Darra E,Abdel-Azeim S,Manara A,Shoji K,Maréchal JD,Mariotto S,Cavalieri E,Perbellini L,Pizza C,Perahia D,Crimi M,Suzuki H

更新日期：2008-08-15 00:00:00

abstract：:Nucleotide Binding Domains (NBDs) are responsible for the ATPase activity of the multidrug resistance protein 1 (MRP1). A series of NBD1-linker-NBD2 chimeric fusion proteins were constructed, expressed and purified, and their ATPase activities were analyzed. We report here that a GST linked NBD1(642-890)-GST-NBD2(1286...

journal_title：Archives of biochemistry and biophysics

authors： Wan L,Liang X,Huang Y

更新日期：2009-05-15 00:00:00

abstract：:Oxidative stress in the small intestine can result in altered cell proliferation, migration, and differentiation of villus-crypt cells. Retinoid metabolism is recognized as an important mediator of cellular differentiation in the intestine. This study examined the effect of oxidative stress in retinoid metabolism in a...

journal_title：Archives of biochemistry and biophysics

authors： Prabhu R,Thomas S,Balasubramanian KA

更新日期：2005-02-15 00:00:00

abstract：:Salicylhydroxamic acid reductase, which catalyzes the reduction of salicylhydroxamic acid to salicylamide, was purified from rat liver cytosol. The purification procedure consisted of fractionation with ammonium sulfate, chromatography with Phenyl-Toyopearl 650, DEAE-cellulose, hydroxyapatite, and Sephadex G-200, and ...

journal_title：Archives of biochemistry and biophysics

authors： Katsura H,Kitamura S,Tatsumi K

更新日期：1993-05-01 00:00:00

abstract：:The insulin receptor from rat skeletal muscle was characterized. Treatment of muscle membranes with the photoactive insulin analog, 125I[N-epsilonB29-monoazidobenzoyl]-insulin revealed a single protein band of 135,000 Da, the alpha subunit. Iodination of total membrane protein followed by Triton X-100 solubilization a...

journal_title：Archives of biochemistry and biophysics

authors： Dubler RE,Whipple JH,Larner J

更新日期：1985-01-01 00:00:00

abstract：:The objective of this study was to develop straightforward processes that could be applied to the large-scale production of β-cryptoxanthin in an attempt to facilitate investigation of its biological activity. An oleoresin obtained from crude extracts of marigold flowers (Tagetes erecta) with approximately 24% total l...

journal_title：Archives of biochemistry and biophysics

authors： Khachik F

更新日期：2018-09-01 00:00:00

abstract：:Assembly of the cellulosome, a large, extracellular cellulase complex, depends upon docking of a myriad of enzymatic subunits to homologous receptors, or cohesin domains, arranged in tandem along a noncatalytic scaffolding protein. Docking to the cohesin domains is mediated by a highly conserved domain, dockerin (DS),...

journal_title：Archives of biochemistry and biophysics

authors： Lytle BL,Volkman BF,Westler WM,Wu JH

更新日期：2000-07-15 00:00:00

abstract：:The reduction of prostaglandin H synthase compound II by ascorbic acid in the presence of diethyldithiocarbamate was studied in 0.1 M phosphate buffer (pH 8.0) at 4.0 +/- 0.5 degrees C, by rapid scan spectrometry and transient state kinetics. A saturation effect and nonzero intercept were observed in the plot of pseud...

journal_title：Archives of biochemistry and biophysics

authors： Hsuanyu Y,Dunford HB

更新日期：1990-09-01 00:00:00

abstract：:Excessive collagen deposition plays a critical role in tumor progression and metastasis. To understand how type IV collagen affects mechanical stiffness and migration, low-collagen-IV-expressing transfectants of B16F10, U118MG, and Huh7 (denoted shCol cells) were established by the lentiviral-mediated delivery of smal...

journal_title：Archives of biochemistry and biophysics

authors： Chen SY,Lin JS,Yang BC

更新日期：2014-08-01 00:00:00

abstract：:Studies have followed the turbidity (OD400 nm) of beta-casein (CN) as temperature (T) increased from 4 to 37 degrees C. Native non-phosphorylated beta-CN showed a turbidity increase above 25 degrees C and precipitated at about 22 degrees C in 5mM Ca+2. These patterns were reproducible upon T-cycling while those of rec...

journal_title：Archives of biochemistry and biophysics

authors： Sood SM,Booth C,Jhawar H,Slattery CW

更新日期：2006-10-01 00:00:00

abstract：:We analyzed the effect of a natural osmolyte, trimethylamine N-oxide (TMAO), on structural properties and conformational stabilities of several proteins under macromolecular crowding conditions by a set of biophysical techniques. We also used the solvent interaction analysis method to look at the peculiarities of the ...

journal_title：Archives of biochemistry and biophysics

authors： Breydo L,Sales AE,Ferreira L,Fedotoff O,Shevelyova MP,Permyakov SE,Kroeck KG,Permyakov EA,Zaslavsky BY,Uversky VN

更新日期：2015-03-15 00:00:00

abstract：:Phenolic phytochemicals such as tannins, which are natural constituents of green tea, red wine, and other plant products, are considered to have cancer-preventive properties. An important endogenous mediator of tumorigenesis is the nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP-1). PARP-1 synthesizes polymers of A...

journal_title：Archives of biochemistry and biophysics

authors： Keil C,Petermann E,Oei SL

更新日期：2004-05-01 00:00:00

abstract：:Three iodinated derivatives of ubiquitin have been synthesized and these derivatives have been characterized in the ubiquitin-dependent protein degradation system. With chloramine-T as the oxidant, a derivative containing monoiodotyrosine is formed in the presence of 1 M KI and a derivative containing diiodotyrosine i...

journal_title：Archives of biochemistry and biophysics

authors： Cox MJ,Haas AL,Wilkinson KD

更新日期：1986-11-01 00:00:00