Formulation and in vitro Evaluation of Alfuzosin Extended Release Tablets Using Directly Compressible Eudragit.

abstract：:Manjisthadi churna has been traditionally used in the Ayurvedic system of medicine and by traditional medical practices of India to treat hyperlipidemia. A rapid, simple and accurate method with high performance thin layer chromatography has been developed to standardised Manjisthadi churna using rubiadin, sennoside a...

journal_title：Indian journal of pharmaceutical sciences

authors： Patel VR,Patel RK

更新日期：2013-01-01 00:00:00

abstract：:Asymmetric membrane capsules are a type of osmotic drug delivery systems. They are nondisintegrating capsules, which utilize osmotic pressure to drive the drug outwards for controlled delivery. Preceded by systems such as elementary osmotic pump, controlled porosity osmotic pump, single composition osmotic tablet this...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo PK,Makar H

更新日期：2013-03-01 00:00:00

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:A simple accurate, sensitive and reproducible spectrofluorimetric method was developed for the analysis of duloxetine hydrochloride in pure and pharmaceutical dosage form. Duloxetine hydrochloride showed strong native fluorescence in 0.05 M acetic acid having excitation at 225 nm and emission at 340 nm. Effect of diff...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shahnawaz S,Kumar CD,Shirwaikar A

更新日期：2008-07-01 00:00:00

abstract：:In the present study, the effect of 2-hydroxy-4-methoxy benzoic acid isolated from roots of Hemisdesmus indicus on the erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-induced diabetic rats was investigated. The streptozotocin-induced diabetic rats were treated with 2-hydroxy-4-methoxy benzo...

journal_title：Indian journal of pharmaceutical sciences

authors： Gayathri M,Kannabiran K

更新日期：2012-09-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhaneshwar SS,Deshpande P,Patil M,Vadnerkar G,Dhaneshwar SR

更新日期：2008-03-01 00:00:00

abstract：:A rapid and sensitive reverse phase high performance liquid chromatographic method is depicted for the qualitative and quantitative assay of letrozole in pharmaceutical dosage forms. Letrozole was chromatographed on a reverse phase C18 column with a mobile phase consisting of acetonitrile and phosphate buffer (pH 7.8)...

journal_title：Indian journal of pharmaceutical sciences

authors： Laha TK,Patnaik RK,Sen S

更新日期：2008-05-01 00:00:00

abstract：:Recent studies have shown that gallic acid and its alkylesters induce apoptosis in different cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of 1-(3,4,5-trihydroxyphenyl)-dodecylb...

journal_title：Indian journal of pharmaceutical sciences

authors： Maioral MF,Bubniak LD,Marzarotto MA,De Moraes AC,Leal P,Nunes R,Yunes RA,Santos-Silva MC

更新日期：2016-01-01 00:00:00

abstract：:A simple, precise, accurate and rapid high performance thin layer chromatographic method has been developed and validated for the estimation of tenoxicam in the microemulsion gels. Tenoxicam was chromatographed on silica gel 60 F(254) TLC plate, as a stationary phase. The mobile phase was toluene: ethyl acetate: formi...

journal_title：Indian journal of pharmaceutical sciences

authors： Chandel S,Barhate CR,Srivastava AR,Kulkarni SR,Kapadia CJ

更新日期：2012-01-01 00:00:00

abstract：:Ethanol extract of Passiflora edulis Sims was analyzed for its antioxidant (1,1-diphenyl-2-picryl hydrazyl radical reducing power methods) and phytochemical analysis. The extract was found effective against the antioxidant test models exhibiting an IC(50) value of 875+/-87.83 mug/ml and showed strong potential antioxi...

journal_title：Indian journal of pharmaceutical sciences

authors： Sunitha M,Devaki K

更新日期：2009-05-01 00:00:00

abstract：:In the current research work an attempt was made to develop "Melt in mouth pellets" (Meltlets(®)) containing 40% herbal extract of soy isoflavones that served to provide antioxidants activity in menopausal women. The process of extrusion-spheronization was optimized for extruder speed, extruder screen size, spheroniza...

journal_title：Indian journal of pharmaceutical sciences

authors： Deshmukh K,Amin P

更新日期：2013-07-01 00:00:00

abstract：:In this paper we report the synthesis of a new family of 4-alkyl isocoumarin derivatives having bromo carbonyl and amino carbonyl group at 3(rd) position of the heterocyclic ring. Synthesis, spectral analysis and bioactivity of new isocoumarin derivatives are discussed in this paper. Some of the synthesized compounds ...

journal_title：Indian journal of pharmaceutical sciences

authors： Yadav P,Purohit NV

更新日期：2011-03-01 00:00:00

abstract：:The aim of this research was to investigate the technique for preparation of coated valproic acid and sodium valproate sustained-release matrix tablets. Different diluents were tested and selected as the effective absorbent for oily valproic acid. Effect of the amount of absorbent and hydroxypropylmethylcellulose on d...

journal_title：Indian journal of pharmaceutical sciences

authors： Phaechamud T,Mueannoom W,Tuntarawongsa S,Chitrattha S

更新日期：2010-03-01 00:00:00

abstract：:Ivermectin, chloramphenicol, ampicillin and tetracycline HCl are common drugs in human and veterinary practice. The purpose of this study is to investigate the possible binding interactions between ivermectin and the antibiotics chloramphenicol, ampicillin and tetracycline HCl. Isothermal titration calorimetry was use...

journal_title：Indian journal of pharmaceutical sciences

authors： Kandeel M,Elgazar W,Kitade Y

更新日期：2012-11-01 00:00:00

abstract：:A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...

journal_title：Indian journal of pharmaceutical sciences

authors： Tian DF,Tian XL,Tian T,Wang ZY,Mo FK

更新日期：2008-05-01 00:00:00

abstract：:Fexofenadine is a selective histamine H(1) receptor antagonist, used for relief of the symptoms of allergy. However its aqueous solubility is very poor. Solid inclusion complexes of fexofenadine and β-cyclodextrin were prepared at the molar ratios of 1:1 and 1:2 by kneading, and coprecipitation methods to improve its ...

journal_title：Indian journal of pharmaceutical sciences

authors： Sapkal NP,Kilor VA,Shewale BD,Bhusari KP,Daud AS

更新日期：2010-05-01 00:00:00

abstract：:In the present study, 2,5-disubstituted-1,3,4-oxadiazoles (3a-o) have been synthesized by the condensation of 4-methoxybenzohydrazide (1) with different aromatic acids (2a-o) in presence of phosphoryl chloride. The structural assignment of this compound (3a-o) has been made on the basis of elemental analysis, UV, IR, ...

journal_title：Indian journal of pharmaceutical sciences

authors： Nagalakshmi G

更新日期：2008-01-01 00:00:00

abstract：:A simple, accurate and precise spectrophotometric method has been developed for simultaneous estimation of escitalopram oxalate and clonazepam in combined dosage form. Simultaneous equation method is employed for simultaneous determination of escitalopram oxalate and clonazepam from combined dosage forms. In this meth...

journal_title：Indian journal of pharmaceutical sciences

authors： Kakde RB,Satone DD

更新日期：2009-11-01 00:00:00

abstract：:Mebeverine hydrochloride is known to suffer from extensive first pass effect. In an attempt to improve its oral bioavailability and possibility to restrict its absorption only to the colon, mebeverine microspheres were prepared by emulsion solvent evaporation method. Four formulations were prepared with varying drug a...

journal_title：Indian journal of pharmaceutical sciences

authors： Dandagi PM,Mastiholimath VS,Gadad AP,Kulkarni AR,Konnur BK

更新日期：2009-07-01 00:00:00

abstract：:Present study reports the development and validation of a simultaneous estimation of metformin and gliclazide in human plasma using supercritical fluid chromatography followed by tandem mass spectrometry. Acetonitrile:water (80:20) mixture was used as a mobile phase along with liquid CO(2) in supercritical fluid chrom...

journal_title：Indian journal of pharmaceutical sciences

authors： Agrawal YK,Gogoi PJ,Manna K,Bhatt HG,Jain VK

更新日期：2010-01-01 00:00:00

abstract：:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar R

更新日期：2008-01-01 00:00:00

abstract：:A gradient reversed phase HPLC method was developed and validated for the analysis of related substances in zonisamide (1,2-benzisoxazole-3-methanesulfonamide), using a Waters Symmetry C8 (150*3.9 mm) column with a flow rate of 1.0 ml/min and detection at 280 nm. The mobile phase component A consisted of a mixture of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Vijayakumar EK,Dhore DM,Kumar M

更新日期：2009-09-01 00:00:00

abstract：:Aqueous extract of leaves of Nelumbo nucifera was investigated on acute stress (immobilization stress)-induced biochemical alterations in Swiss mice. The animals were also subjected to acute physical stress (swimming endurance test) and acute chemical stress (writhing test) to gauge the antistress potential of the ext...

journal_title：Indian journal of pharmaceutical sciences

authors： Kulkarni MP,Juvekar AR

更新日期：2008-05-01 00:00:00

abstract：:Several 4-arylidene-2-phenyl-1-(2,4,5-trichlorophenyl)-1H-imidazol-5(4H)-ones (4a-q), N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-4-chlorobenzamides (5a-o) and N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-2,4-dichlorobenzamides (6a-m) were prepared. All newly synthesized compounds have been ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai NC,Bhavsar AM,Baldaniya BB

更新日期：2009-01-01 00:00:00

abstract：:Essential oils extracted from flower petals of palmarosa (Cymbopogon martini), evening primrose (Primula rosea), lavender (Lavandula angustifolia) and tuberose (Polianthus tuberosa) were tested for their antibacterial activities against gram-positive and gram-negative bacteria. Different concentrations of each essenti...

journal_title：Indian journal of pharmaceutical sciences

authors： Lodhia MH,Bhatt KR,Thaker VS

更新日期：2009-03-01 00:00:00

abstract：:The present study depicts the development of a validated RP-HPLC method for the determination of the pamabrom in presence of degradation products or other pharmaceutical excipients. Stress study was performed on pamabrom and it was found that it degrade sufficiently in acidic, alkali and oxidative condition but less d...

journal_title：Indian journal of pharmaceutical sciences

authors： Shah U,Kavad M,Raval M

更新日期：2014-05-01 00:00:00

abstract：:A simple and sensitive spectrofluorimetric method has been developed for the estimation of brimonidine tartrate in pure and eye drops. Linearity was obeyed in the range of 0.2-3.0 ΅g/ml in dimethyl formamide as solvent at an emission wavelength (λem) of 530 nm after excitation wavelength (λex) of 389 nm with good corr...

journal_title：Indian journal of pharmaceutical sciences

authors： Sunitha G,Bhagirath R,Alapati VR,Ramakrishna K,Subrahmanyam CV,Anumolu PD

更新日期：2013-11-01 00:00:00

abstract：:Breast cancer is the foremost common malignancy among the female population around the world. Female breast cancer incidence rates have increased since 1980, slowed in 1990, the rate of increase have leveled off since 2001. In spite of the advances in the early detection, treatment, surgery and radiation support, almo...

journal_title：Indian journal of pharmaceutical sciences

authors： Mohan A,Ponnusankar S

更新日期：2013-05-01 00:00:00

abstract：:A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan me...

journal_title：Indian journal of pharmaceutical sciences

authors： Rote AR,Bari PD

更新日期：2010-01-01 00:00:00