当前位置： SCI文献检索 > NEUROCHEMISTRY INTERNATIONAL期刊下所有文献 > Correlation between rotational behaviors and neurochemical changes associated with damage of rat striatum: Analysis using unilateral microinjection of kainic acid.

Correlation between rotational behaviors and neurochemical changes associated with damage of rat striatum: Analysis using unilateral microinjection of kainic acid.

Abstract：

:The correlation between rotational behaviors and neurochemical changes associated with the striatal damage induced by an unilateral microinjection of kainic acid were investigated. Shortly after the unilateral striatal injection of kainic acid, rats exhibited contralateral rotational behaviors, and these changes were antagonized by the simultaneous striatal injection of haloperidol. On the other hand, systemic injection of methamphetamine to animals having the lesion on nigro-striatal dopaminergic neurons exhibited ipsilateral turnings. In addition, it was found that the release of [(14)C]dopamine from striatal slices was increased by the in vitro addition of kainic acid. Following 2 days after the striatal injection of kainic acid and thereafter, the rats exhibited ipsilateral rotational behaviors and microinjection of muscimol into the ipsilateral substantia nigra of these animals altered turning movements to a contralateral type. Simultaneous nigral injection of bicuculline antagonized to the muscimol-induced contralateral turnings. These results suggest that the increase of dopamine release from dopaminergic neurons in the striatum may be involved in the occurrence of contralateral turning behaviors observed shortly after the striatal kainic acid treatment. The present results also suggest that changes in the functional states of striatonigral GABA-ergic neurons may play an important role in the occurrence of ipsilateral rotational movements at a late stage following the striatal injection of this agent.

journal_name

Neurochem Int

journal_title

Neurochemistry international

authors

Kuriyama K,Kurihara E

doi

10.1016/0197-0186(82)90044-4

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

551-5

issue

6

eissn

0197-0186

issn

1872-9754

pii

0197-0186(82)90044-4

journal_volume

4

pub_type

杂志文章

相关文献

NEUROCHEMISTRY INTERNATIONAL文献大全
  • Preferential release of newly synthesized [(3)H]GABA from striatal slices to preloaded [(3)H]GABA.

    abstract：:The release of [(3)H]GABA which is newly synthesized from [(3)H]l-glutamic acid (GLU) has been examined using striatal slices obtained from the rat brain. It was found that 8-10% of [(3)H]GLU transported was converted to [(3)H]GABA during the incubation of striatal slices in the presence of nipecotic acid (5 x 10(?5) ...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(84)90045-7

    authors： Yoneda Y,Kanmori K,Takahashi M,Zuo PP,Paik IH,Kuriyama K

    更新日期：1984-01-01 00:00:00

  • A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves.

    abstract：:Acyl-CoA synthetase activity was investigated in membrane fractions from normal and Trembler mouse sciatic nerves. Stearoyl-CoA synthesis in the Trembler assays was always about twice that observed in the control experiments under various conditions of CoA and ATP concentrations. In experiments using varying concentra...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(85)90035-x

    authors： Boiron F,Heape AM,Cassagne C

    更新日期：1985-01-01 00:00:00

  • Antidepressants attenuate the dexamethasone-induced decrease in viability and proliferation of human neuroblastoma SH-SY5Y cells: a involvement of extracellular regulated kinase (ERK1/2).

    abstract：:Excessive glucocorticoid levels in depressed patients have been associated with atrophic changes in some brain regions, but only few studies suggest that some antidepressants can interfere with deleterious effect of glucocorticoids on neuronal cells. The aim of the present study was to examine the effect of dexamethas...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2013.07.007

    authors： Leskiewicz M,Jantas D,Regulska M,Kaczanowska J,Basta-Kaim A,Budziszewska B,Kubera M,Lason W

    更新日期：2013-11-01 00:00:00

  • TDP-43 levels are higher in platelets from patients with sporadic amyotrophic lateral sclerosis than in healthy controls.

    abstract：:TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of ubiquitinated inclusions in motor neurons of sporadic amyotrophic lateral sclerosis (ALS). TDP-43 is ubiquitously expressed and the majority of TDP-43 is normally localized to the nucleus. In motor neurons of patients with ALS, TDP-43 is not locali...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2018.12.009

    authors： Hishizawa M,Yamashita H,Akizuki M,Urushitani M,Takahashi R

    更新日期：2019-03-01 00:00:00

  • An insight into the vision impairment following traumatic brain injury.

    abstract：:Traumatic brain injury (TBI) is one of the major cause of morbidity and mortality and it affects more than 1.7 million Americans each year. Depending on its location and severity, TBI leads to structural and functional damage in several parts of the brain such as cranial nerves, optic nerve tract or other circuitry in...

    journal_title：Neurochemistry international

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuint.2017.01.019

    authors： Sen N

    更新日期：2017-12-01 00:00:00

  • The effect of interferon beta-1b on cytokine-induced adhesion molecule expression.

    abstract：:Interferon beta-1b (IFN beta-1b) (Betaseron) has been recently shown to alter the course of multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) where migration of activated lymphocytes across the blood-brain barrier (BBB) is a critical step in the pathogenesis of this dis...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(96)00081-2

    authors： Jiang H,Williams GJ,Dhib-Jalbut S

    更新日期：1997-04-01 00:00:00

  • Depolarization-induced changes of free intracellular Ca(2+) concentration and of [(3)H]dopamine release in undifferentiated and differentiated PC12 cells.

    abstract：:The rat pheochromocytoma cell line PC12 undergoes morphological differentiation into neurone-like cells when exposed to nerve growth factor (NGF). We found that in PC12 cells the enzymatic activity of choline-acetyltransferase and of tyrosine hydroxylase changed very little during NGF exposure, while tyrosine hydroxyl...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(90)90142-g

    authors： Reber BF,Porzig H,Becker C,Reuter H

    更新日期：1990-01-01 00:00:00

  • Effect of oxygen and glucose availability on the glycolytic rate in neuroblastoma cells under different conditions of culture.

    abstract：:Neuroblastoma cells, cultivated on plastic dishes, in presence of 15 mM glucose resist very well to hypoxia. Cells incubated on plastic dishes, if left unshaken, showed a Pasteur effect at an oxygen concentration below 10%. Oxygen diffusion was the limiting factor in these plastic dishes since improved oxygen diffusio...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(84)90116-5

    authors： Pauwels PJ,Opperdoes FR,Trouet A

    更新日期：1984-01-01 00:00:00

  • 15,16-dihydrotanshinone I suppresses the activation of BV-2 cell, a murine microglia cell line, by lipopolysaccharide.

    abstract：:Microglial activation has been implicated in neurodegenerative diseases. Therefore, inhibition of inflammation mediated by microglia is a strategy in neurodegenerative disease therapy. In this study, we isolated cryptotanshinone and 15,16-dihydrotanshinone I from Salvia miltiorrhiza, a traditional Korean herb medicine...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2005.07.004

    authors： Lee P,Hur J,Lee J,Kim J,Jeong J,Kang I,Kim SY,Kim H

    更新日期：2006-01-01 00:00:00

  • Presenilin-1 and the amyloid precursor protein are transported bidirectionally in the sciatic nerve of adult rat.

    abstract：:The amyloid precursor protein (APP) and presenilin-1 (PS-1) are not only of importance for the normal functioning of the various neurons, but also play central roles in the pathogenesis of Alzheimer's disease (AD). Through the use of immunohistochemical and Western blot techniques, the bidirectional axonal transport o...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(02)00014-1

    authors： Papp H,Pakaski M,Kasa P

    更新日期：2002-12-01 00:00:00

  • Truncation of human dopamine transporter by protease calpain.

    abstract：:It has been shown recently that the N-terminal domain of the dopamine transporter (DAT) plays a role in several transporter functions. Here we provide evidence for a possible cellular mechanism of how the N-terminus of dopamine transporter might be removed in vivo. We isolated a recombinant N-terminal protein region o...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2008.04.001

    authors： Franekova V,Baliova M,Jursky F

    更新日期：2008-06-01 00:00:00

  • Study on the possible involvement of protein kinases in the modulation of brain presynaptic sodium channels; comparison with calcium channels.

    abstract：:A possible modulatory role of kinases on voltage sensitive Na+ channels of presynaptic brain nerve endings was investigated by testing the effect of several kinase activators and inhibitors on the elevation of [Nai] induced by veratridine in mouse brain synaptosomes loaded with a selective Na+ indicator dye. Veratridi...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(97)00065-x

    authors： Sitges M,Peña F,Chiu LM,Guarneros A

    更新日期：1998-02-01 00:00:00

  • Norepinephrine metabolism in the cerebellum of the purkinje cell degeneration (pcd) mutant mouse.

    abstract：:Norepinephrine (NE) metabolism in brain regions was studied in the Purkinje cell degeneration (pcd) mutant mouse. The Purkinje cells, which are target cells for noradrenergic (NA) neurons, degenerate completely in the pcd mutant mouse between 17 and 45 days of age, but the NA terminals remain intact. The purpose of th...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(87)90170-7

    authors： Ghetti B,Perry KW,Fuller RW

    更新日期：1987-01-01 00:00:00

  • Release of acid-soluble radioactivity from rapidly transported proteins in homogenates of rabbit superior colliculus.

    abstract：:An intraocular injection of [(3)H]proline was used to label rabbit retinal ganglion cells including components subjected to axonal transport. Degradation of rapidly axonally transported labelled proteins was estimated in an in vitro system using homogenates of the nerve terminal regions. The energy requirements of thi...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(85)90061-0

    authors： Gustavsson S,Karlsson JO

    更新日期：1985-01-01 00:00:00

  • Substrate-induced up-regulation of Na(+)-dependent glutamate transport activity.

    abstract：:Sodium-dependent transporters regulate extracellular glutamate in the CNS. Recent studies suggest that the activity of several different neurotransmitter transporters can be rapidly regulated by a variety of mechanisms. In the present study, we report that pre-incubation of primary 'astrocyte-poor' neuronal cultures w...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(00)00018-8

    authors： Munir M,Correale DM,Robinson MB

    更新日期：2000-08-01 00:00:00

  • The venom of Conus pennaceus inhibits the binding of [3H]neuropeptide Y by direct interaction with the radioligand.

    abstract：:The venom from the marine snail Conus pennaceus inhibits the binding of [3H]neuropeptide Y to calf brain membranes (Czerwiec et al., 1996a) and, in the present study, also to rat forebrain membranes. These membranes contain about 80% Y1- and 20% Y2-receptors. The inhibition by the venom was concentration-dependent wit...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(97)00063-6

    authors： Diallo B,Vanderheyden PM,De Backer JP,Vauquelin G

    更新日期：1998-01-01 00:00:00

  • Gallamine and tubocurarine as possible allosteric modifiers of soluble acetylcholinesterase activity at physiological ionic strength.

    abstract：:Esters of dimethylcarbamic acid are known to be poor substrates of acetylcholinesterase. They carbamylate the active catalytic site of the enzyme and the subsequent decarbamylation is a slow but measurable process. Similarly, acetylcholinesterase can be phosphonylated, and the dephosphonylation is extremely slow. Rapi...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(81)90061-9

    authors： Dawson RM,Poretski M,Upsher CM

    更新日期：1981-01-01 00:00:00

  • Ferrous ion activates the less active form of human adrenal tyrosine hydroxylase.

    abstract：:The less active form of human tyrosine hydroxylase has been previously reported but its physiological role is unknown. We partially purified the less active form of tyrosine hydroxylase from human adrenals, and examined differences in the properties of the active and less active forms. We succeeded in activation of th...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(90)90123-b

    authors： Ishii A,Kiuchi K,Matsuyama M,Satake T,Nagatsu T

    更新日期：1990-01-01 00:00:00

  • The unresolved role of mitochondrial DNA in Parkinson's disease: An overview of published studies, their limitations, and future prospects.

    abstract：:Parkinson's disease (PD), a progressive neurodegenerative disorder, has long been associated with mitochondrial dysfunction in both sporadic and familial forms of the disease. Mitochondria are crucial for maintaining cellular homeostasis, and their dysfunction is detrimental to dopaminergic neurons. These neurons are ...

    journal_title：Neurochemistry international

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuint.2019.104495

    authors： Müller-Nedebock AC,Brennan RR,Venter M,Pienaar IS,van der Westhuizen FH,Elson JL,Ross OA,Bardien S

    更新日期：2019-10-01 00:00:00

  • Distribution of an endogenous lectin during myogenesis as measured by antilectin antibodies.

    abstract：:Antibodies to electrolectin, a lectin endogenous to embryonic skeletal muscle, have been used to study the distribution of lectin during myogenesis in L(6) cells by using immunohistofluorescence microscopy. Evidence for both surface and cytoplasmic forms of lectin is presented. Cytoplasmic lectin does not appear to be...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(80)90041-8

    authors： Podleski TR

    更新日期：1980-01-01 00:00:00

  • Neuroserpin up-regulation in the Alzheimer's disease brain is associated with elevated thyroid hormone receptor-β1 and HuD expression.

    abstract：:Neuroserpin, the major inhibitor of tissue plasminogen activator (tPA) in brain, has been shown to be up-regulated in Alzheimer's disease (AD). Inhibition of tPA activity leads to reduced brain levels of plasmin, one of the main enzymes responsible for the degradation and clearance of amyloid-beta and its plaques from...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2013.08.010

    authors： Subhadra B,Schaller K,Seeds NW

    更新日期：2013-11-01 00:00:00

  • Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity.

    abstract：:Cholesterol, a molecule critical for cellular function, is found in particular high concentration in the brain and has been implicated to synaptic plasticity and neuronal regeneration. This study was undertaken to investigate the mechanism by which cholesterol shortage modulates glutamate (Glu)-induced excitotoxicity ...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(03)00003-2

    authors： Chou YC,Lin SB,Tsai LH,Tsai HI,Lin CM

    更新日期：2003-08-01 00:00:00

  • Modulation of choline acetyltransferase synthesis by okadaic acid, a phosphatase inhibitor, and KN-62, a CaM kinase inhibitor, in NS-20Y neuroblastoma.

    abstract：:Choline-O-acetyltransferase (ChAT) is the enzyme which catalyses the biosynthesis of the neurotransmitter acetylcholine in cholinergic neurons. Here we show that in mouse cholinergic NS-20Y neuroblastoma cells cultured in the presence of either okadaic acid (serine/threonine phosphatases 1 and 2A inhibitor) or KN-62 (...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/s0197-0186(00)00064-4

    authors： Pahud G,Bontron S,Eder-Colli L

    更新日期：2001-01-01 00:00:00

  • Study of synergistic role of allogenic skin-derived precursor differentiated Schwann cells and heregulin-1β in nerve regeneration with an acellular nerve allograft.

    abstract：:Development of tissue structure and three-dimensional microenvironment is crucial for regeneration of axons in the peripheral nerve repair. In this study we aimed to evaluate the efficacy of nerve regeneration by using an acellular nerve allograft (ANA) injected with allogenic skin-derived precursor differentiated Sch...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2016.04.003

    authors： Wang H,Wu J,Zhang X,Ding L,Zeng Q

    更新日期：2016-07-01 00:00:00

  • PKCβ-dependent phosphorylation of the glycine transporter 1.

    abstract：:The extracellular levels of the neurotransmitter glycine in the brain are tightly regulated by the glycine transporter 1 (GlyT1) and the clearance rate for glycine depends on its rate of transport and the levels of cell surface GlyT1. Over the years, it has been shown that PKC tightly regulates the activity of several...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2011.08.006

    authors： Vargas-Medrano J,Castrejon-Tellez V,Plenge F,Ramirez I,Miranda M

    更新日期：2011-12-01 00:00:00

  • Are nestin-positive mesenchymal stromal cells a better source of cells for CNS repair?

    abstract：:In recent years there has been a great deal of research within the stem cell field which has led to the definition and classification of a range of stem cells from a plethora of tissues and organs. Stem cells, by classification, are considered to be pluri- or multipotent and have both self-renewal and multi-differenti...

    journal_title：Neurochemistry international

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuint.2016.08.001

    authors： Lindsay SL,Barnett SC

    更新日期：2017-06-01 00:00:00

  • Degradation of survival motor neuron (SMN) protein is mediated via the ubiquitin/proteasome pathway.

    abstract：:Homozygous deletion or mutation in the survival motor neuron (SMN)1 gene causes proximal spinal muscular atrophy (SMA), whereas SMN2 acts as a modifying gene that can influence the severity of SMA. It has been suggested that restoration of the SMN protein level in neuronal cells may prevent cell loss and may be helpfu...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2004.04.005

    authors： Chang HC,Hung WC,Chuang YJ,Jong YJ

    更新日期：2004-12-01 00:00:00

  • Early long-term exposure with caffeine induces cross-sensitization to methylphenidate with involvement of DARPP-32 in adulthood of rats.

    abstract：:Chronic ingestion of caffeine causes dependence and sleep disturbance in children and adolescents. In rodents, the administration of caffeine may produce behavioral cross-sensitization to some psychostimulants, such as dopaminergic psychoactive drugs. Methylphenidate (MPH; Ritalin) is a psychostimulant used in pediatr...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2009.03.015

    authors： Boeck CR,Marques VB,Valvassori SS,Constantino LC,Rosa DV,Lima FF,Romano-Silva MA,Quevedo J

    更新日期：2009-09-01 00:00:00

  • Purification of peroxisomal fraction from rat brain.

    abstract：:A purification procedure to obtain peroxisomes (microperoxisomes) from the brain of suckling rats is reported. A P2 fraction, (crude light mitochondria) frozen and thawed seven times, was subfractionated yielding a P4 fraction, 4-fold enriched in catalase activity with respect to the cytoplasmic extract S1. The P4 fra...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/0197-0186(93)90116-m

    authors： Cimini AM,Moreno S,Giorgi M,Serafini B,Cerú MP

    更新日期：1993-09-01 00:00:00

  • Norepinephrine acts as D1-dopaminergic agonist in the embryonic avian retina: late expression of beta1-adrenergic receptor shifts norepinephrine specificity in the adult tissue.

    abstract：:Dopamine is the main catecholamine found in the chick retina whereas norepinephrine is only found in trace amounts. We compared the effectiveness of dopamine and norepinephrine in promoting cyclic AMP accumulation in retinas at embryonic day 13 (E13) and from post-hatched chicken (P15). Dopamine (EC(50)=10microM) and ...

    journal_title：Neurochemistry international

    pub_type： 杂志文章

    doi：10.1016/j.neuint.2006.08.004

    authors： Kubrusly RC,Ventura AL,de Melo Reis RA,Serra GC,Yamasaki EN,Gardino PF,de Mello MC,de Mello FG

    更新日期：2007-01-01 00:00:00