Abstract:
INTRODUCTION AND HYPOTHESIS:Mesh-augmented reconstructive surgery for pelvic organ prolapse (POP) does not meet clinical expectations. A tissue-engineered fascia equivalent needs to be developed. METHODS:Human vaginal fibroblasts (HVFs) from 10 patients were characterized in vitro. Eligible HVFs and a biodegradable scaffold were used to fabricate a fascia equivalent, which was then transplanted in vivo. RESULTS:The cultured HVFs were divided into high (n = 6) or low (n = 4) collagen I/III ratio groups. Cells of the high-ratio group exhibited significantly higher proliferation potential than those of the low-ratio group (P < 0.05). A fascia equivalent was made with HVFs of the high-ratio group. In the subsequent animal study, a well-organized neo-fascia formation containing HVFs could be traced up to 12 weeks after transplantation. CONCLUSIONS:Our results suggest that a tissue-engineered fascia could be developed from HVFs in vitro and in vivo, which might be an effective treatment for POP in the future.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Hung MJ,Wen MC,Hung CN,Ho ES,Chen GD,Yang VCdoi
10.1007/s00192-010-1168-3subject
Has Abstractpub_date
2010-09-01 00:00:00pages
1085-93issue
9eissn
0937-3462issn
1433-3023journal_volume
21pub_type
杂志文章abstract:INTRODUCTION AND HYPOTHESIS:Standardized terminology for surgical procedures commonly performed to treat stress urinary incontinence in women is needed to facilitate research, clinical care, and teaching in female pelvic medicine and reconstructive surgery. METHODS:This report combines the input of members of the Amer...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04237-0
更新日期:2020-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the present study was to determine possible correlations between mesh retraction after anterior vaginal mesh repair and de novo stress urinary incontinence (SUI), overactive bladder (OAB), and vaginal pain symptoms. METHODS:One hundred and three women with symptomatic prolapse of...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2131-x
更新日期:2013-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Several studies have indicated depression and anxiety to be associated with urinary incontinence (UI), however, the strength of the associations varies widely. The objective of this study was to determine these associations in a large survey. METHODS:In a cross-sectional population-based su...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1564-3
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Currently, there is no global outcome assessment index in prolapse research. Patient Global Impression of Improvement (PGI-I) has only been validated in incontinence. Our aim was to validate its use following prolapse surgery. METHODS:Women with prolapse were recruited from waiting lists an...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-1069-5
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Female sexual function disorders (FSFDs) have received less attention than male sexual function disorders, despite being more prevalent. Furthermore, most available literature is on the effect of vaginal delivery (VD) on sexual function, and studies on the effect of caesarean section (CS) ar...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04541-9
更新日期:2020-10-10 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The high uterosacral vault suspension (HUVS) is a vaginal approach for treating apical prolapse that provides shorter operative and recovery times and is associated with lower morbidity rates. Success rates reported for this technique are comparable with the abdominal sacrocolpopexy (SCP); h...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-015-2666-0
更新日期:2015-08-01 00:00:00
abstract::Hydatid cyst is a parasitic infectious disease caused by Echinococcus granulosus. Although the most common site for this parasite is liver, it can be seen in almost all organs. Extrahepatic localization is reported in 14-19% of all cases of abdominal hydatid disease. We report the case of a large echinococcal cyst loc...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1201-6
更新日期:2010-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To estimate the incidence rates of stress urinary incontinence (SUI) surgery among Finnish women from 1987 to 2009 by age, and to evaluate the trends in SUI surgery. METHODS:We conducted a retrospective register-based study. All SUI procedures on adult women over age 18 years in Finland wer...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2926-z
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to compare the efficacy and safety of transvaginal trocar-guided polypropylene mesh insertion with traditional colporrhaphy for treatment of anterior vaginal wall prolapse. METHODS:This is a randomized controlled trial in which women with advanced anterior vaginal w...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-013-2092-0
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Support of the vaginal apex is paramount for a durable repair of pelvic organ prolapse (POP). Our aim is to assess national utilization of apical suspension procedures for the surgical treatment of complete POP. We hypothesize that there might be a high rate of apical suspension with advance...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04342-0
更新日期:2020-06-08 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to evaluate the long-term effect of thermoablative fractional CO2 laser (TACO2L) as an alternative treatment for early stages of stress urinary incontinence (SUI) in postmenopausal women with genitourinary syndrome of menopause. METHODS:A total of 161 postmenopausa...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3352-1
更新日期:2018-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to compare medium-term efficacy and safety of a partially absorbable mesh kit and native tissue repair in pelvic organ prolapse (POP). MATERIALS AND METHODS:Women with primary POP stage ≥ II were randomized to transvaginal trocar-guided partially absorbable mesh (81 women)...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00192-018-3757-5
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of soy isoflavone extract (SIE) on the uterus and urethra of castrated female rats. METHODS:Ovariectomized adult virgin Wistar rats (n = 45) received, for 30 days: placebo (GI); SIE from day 5 of castration (GII); or day 28 of castration (GIII). A standardized SIE was administered by g...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-0995-6
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The Patient Global Impression of Improvement (PGI-I) and International Consultation of Incontinence Questionnaire - Short Form (ICIQ-SF) are validated instruments for the assessment of patient reported outcome measures (PROM) following treatment of stress urinary incontinence (SUI). However,...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3070-0
更新日期:2017-01-01 00:00:00
abstract::Genitourinary syndrome of menopause (GSM) is common among postmenopausal women, but, in general, not all of the patients seek medical advice as this sensitive issue can cause them embarrassment. OBJECTIVES:To explore the prevalence of GSM among Thai postmenopausal women and their disclosure of and attitude towards GS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03991-0
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The incidence of vesico-vaginal fistulas after hysterectomies for benign indications in developed countries is less than one percent. The objective of this video is to demonstrate an easy-to-follow, step-by-step approach to repairing a small, uncomplicated vesico-vaginal fistula transvaginal...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3471-8
更新日期:2018-05-01 00:00:00
abstract::We report a case of enterococcus lumbar osteomyelitis that developed after post-operative pyelonephritis. A 78-year-old G2P2 with Stage III uterovaginal prolapse and genuine stress urinary incontinence who underwent laparoscopic-assisted vaginal hysterectomy, high uterosacral ligament suspension, tension-free vaginal ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1836-6
更新日期:2013-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We sought to examine the change in utilization of the midurethral sling (MUS) for the treatment of stress urinary incontinence (SUI) after the 2011 US FDA communication regarding transvaginal mesh. METHODS:This is a retrospective cohort study evaluating surgical utilization of MUS at a mana...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04597-7
更新日期:2020-11-18 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Several modifications of sacrospinous ligament fixation (SLF) are described. METHODS:This study presents a standardised SLF technique. Perioperative course and outcome are compared retrospectively after surgery is performed by experienced surgeons or by residents. RESULTS:Two hundred three...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1341-8
更新日期:2011-03-01 00:00:00
abstract::Posterior sacrospinous fixation (SSF) was first described by Amreich in 1950 and then modified by Richter in 1968. The main difficulty of this technique is the pararectal approach with dissection under visual guidance. Our aim was to teach young surgeons to use this alternative technique for apical suspension and to f...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04149-8
更新日期:2020-07-01 00:00:00
abstract::In this article, we provide a concise review of the literature on nocturia and its interference with sleep and, consequently, on quality of life. There are few studies addressing the possible influences of nocturia on sleep disruption. Nocturia is a potential contributor to sleep disorders because affected individuals...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-011-1525-x
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Bladder pain syndrome (BPS) is a disease of unknown etiology defined as an unpleasant sensation related to the bladder, associated with lower urinary tract symptoms of more than 6 weeks' duration, in the absence of any identifiable causes. Despite its impact on quality of life (QoL) and soci...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04075-9
更新日期:2019-11-01 00:00:00
abstract::The concept of genitourinary syndrome of menopause (GSM) was recently introduced and has been gaining widespread use. While some justifications for its introduction are straightforward, others may be questionable. Numerous unspecific symptoms and signs were included in the definition of the syndrome, but the minimum n...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-017-3295-6
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Modern classifications of pelvic floor movements are based on pelvic floor assessment in a static midsagittal plane. This study presents a new and potentially useful 3D noninvasive tool for studying pelvic floor mobility in women with pelvic organ prolapse (POP). MATERIALS AND METHODS:Thirt...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-016-2948-1
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:In this retrospective study, a comparison is made of the clinical efficacy of two stress urinary incontinence treatment apparatuses, a single-incision sling and a transobturator sling. METHODS:Eighty-five (single-incision n=43, transobturator n=42) consecutive patients were included in this study. Clinica...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1942-5
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Minimally invasive sacral colpopexy has increased over the past decade, with many senior physicians adopting this new skill set. However, skill acquisition at an academic institution in the presence of postgraduate learners is not well described. This manuscript outlines the introduction of ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2085-z
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To describe the impact of native tissue vaginal reconstruction on pelvic anatomy using dynamic magnetic resonance imaging. METHODS:This prospective single-cohort observational study involved women undergoing native tissue reconstruction with intraperitoneal vaginal vault suspension for pelv...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04571-3
更新日期:2020-10-22 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Ureteral injury during gynecological surgery can be managed in a variety of ways, from endoscopic stent placement to ureteroneocystotomy with accompanying psoas hitch and/or Boari flap. The majority of these occur during hysterectomy; therefore, gynecologic surgeons may not be as familiar wi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04627-4
更新日期:2021-01-06 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim was to develop a nomogram based on clinical and surgical factors to predict the likelihood of voiding dysfunction after surgery for deep endometriosis. METHODS:This was a retrospective study of 789 patients (training set) who underwent surgery for deep endometriosis with colorectal ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04428-9
更新日期:2020-07-11 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:This study aims to assess anatomical and functional results of bilateral anterior sacrospinous ligament suspension associated with paravaginal repair with mesh. METHODS:Forty-eight patients were operated between March 2007 and August 2008. Mean age was 67 years old. Nineteen patients (39.6%...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-009-1036-1
更新日期:2010-03-01 00:00:00