Abstract:
:Aspirin at a dose of 50 mg/kg body weight was found to decrease the activity of the rat intestinal brush border membrane (BBM) - associated enzymes such as the sucrase, lactase, maltase and alkaline phosphatase. Aspirin treatment also led to a decrease in the microviscosity in the native as well as the benzyl alcohol treated membrane which might be due to the lipid peroxidative damage in the membrane. Physical correlation of the membrane oxidative damage was evident as the Fourier Transformation Infra Red (FTIR) study of the Aspirin treated membrane, which include an increased proportion of gauche to trans conformer, shift in the methylene C-H asymmetric and symmetric stretching frequencies, C = O double bond stretching, NH bending, antisymmetric (N)-CH3 bending, C-N stretching and antisymmetric CNC stretching while there was no change in the CH2 wagging and twisting as well as in NH-bending amide bond I and II. Aspirin treatment also caused an alteration in the glucose and histidine transport, as evident by a decreased Vmax value while the apparent Km remaining unchanged in the control and Aspirin-treated animals confirming that there was no change in the substrate affinity constant of the membrane transport proteins for the glucose and the basic amino acid, although the rate of transport decreased considerably. There was a decrease noted in the energy of activation of glucose and histidine transport when studied at different temperature but no change in the temperature of phase transition in the BBM with Aspirin treatment, thus implying that perhaps the thermotropic phase transition in the membrane may have relatively little effect on the transport processes. The result suggests an underlying molecular mechanism indicating the implied membrane damage by Aspirin, an important member of the non-steroidal antiinflammatory drug (NSAID) family which could possibly through an oxidative damage may lead to an altered molecular structure, physical state and biological functions of the intestinal membrane.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Kaur G,Kaur J,Mittal N,Nath Sanyal Ssubject
Has Abstractpub_date
2010-03-01 00:00:00pages
290-8issue
2eissn
0212-1611issn
1699-5198pii
S0212-16112010000200014journal_volume
25pub_type
杂志文章abstract::A review of the following points was performed: Factors favouring the development and presence of malnutrition among hospitalized patients. Useful parameters in nutritional evaluation. Types of malnutrition. The Chang nutritional evaluation protocol is used in our Hospital, which is simple, inexpensive, reliable, spec...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract:INTRODUCTION:Obesity and diabetes are diseases with high prevalence worldwide. There is currently no effective medical treatment for combat the weight gain. It is precursor of diseases such as diabetes or metabolic syndrome. It is necessary to know if weight gain has cumulative effects on the glycemic and lipid metabol...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.29.5.7288
更新日期:2014-05-01 00:00:00
abstract::Introducción: el sobrepeso y la obesidad se asocian a una mayor probabilidad de que el parto finalice en cesárea. Dado que dicho incremento del riesgo podría estar sesgado por variables de confusión como la diabetes o la hipertensión, en el presente trabajo pretendemos determinar si este riesgo persiste tras ser ajust...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.778
更新日期:2016-11-29 00:00:00
abstract::The establishing of indications for parenteral nutrition and the evaluation criteria for the nutritional state of patients used in selecting the candidates for parenteral nutrition are the two main pillars upon which the rationalization of nutritional therapy iv is based. This is an important aspect which conditions t...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::Protein-losing gastroenteropathy (PLE) consists on an active digestive tract protein loss syndrome and it is related to some diseases. After a wide research into bibliography (MEDLINE - Pubmed),we have found few references to this gastroenteropathy as a cause of hypoalbuminemia related to malnutrition. This has motiva...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000600041
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:The pathophysiologic mechanisms that account for the development and persistence of anorexia nervosa (AN) remain unclear. With respect to the neuropsychological functioning, the executive functions have been reported to be altered, especially cognitive flexibility and decision-making processes. OBJECTIVES...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2014.29.3.7149
更新日期:2014-03-01 00:00:00
abstract::Objetivos: oligoelementos como zinc (Zn), hierro (Fe) y cobre (Cu) tienen una influencia significativa en el mantenimiento de la función inmune y del metabolismo normales; modulan la función immune e influyen en la susceptibilidad del organismo ante infecciones. Pero la relación entre trazas de estos elementos y la br...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.97
更新日期:2016-03-25 00:00:00
abstract::Resection of long segments of the small bowel may cause variable degrees of malabsorption. Therefore, the results of the resection will depend on the length and location of the resected segment, and on the age of the patient and the underlying disease that motivated the resection. The implementation of Nutritional Sup...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Patient diagnosed with Crohn's Disease with inflammatory pattern that evolves stenosing-piercing, causing abdominal perforation and fecal peritonitis. She was underwent to three surgeries, leading to numerous complications and a torpid clinical course. Given the state of malnutrition on admission it was prescribed Tot...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2012.27.5.5884
更新日期:2012-09-01 00:00:00
abstract::When a patient needs parenteral or enteral nutrition, be it in a transitory way or as a permanent form, and hospitalization is not strictly required, this treatment should take place in the home of the patient whenever possible. The support with artificial nutrition can be equally efficient, improving the life expecta...
journal_title:Nutricion hospitalaria
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:1995-09-01 00:00:00
abstract:AIM:To analyse the calcium contribution of one unit of fermented milk enriched with calcium and vitamin D in the daily calcium intake for postmenoupausic women. SUBJECTS:261 postmenoupausic women. METHODS:28 day duration of exploratory, nutritional trial. All subjects received dietary advice on how to increase calciu...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章
doi:10.1590/S0212-16112012000200028
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:the aim of this study was to assess the fatty acid profile of two cured meat products of similar manufacturing processes and characteristics, dry-cured ham (JA) and cecina (CE), a type of dry-cured beef. The obtained results were discussed in terms of the effects that each singular fatty aci...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.1.8911
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:physical fitness is a powerfull indicator of the health coindition in childhood, adolescence and adulthood. This research is performed in order to determine the age and gender stratified reference values for healthy physical fitness for Macodonian children and adolescents and to identify signicicant gender d...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1881
更新日期:2018-12-03 00:00:00
abstract:Introducción:el propósito de este estudio fue investigar la eficacia del entrenamiento diario de una repetición máxima (1RM) de la sentadilla en fuerza máxima. Material y método:tres levantadores de peso de competición realizaron la sentadilla durante 37 días consecutivos y se reportan como casos individuales. Partici...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.129
更新日期:2016-03-25 00:00:00
abstract:OBJECTIVE:Observation of weight loss and the maximum time that individualized dietary treatment qualitative and quantitative is shown to be effective. METHOD:4625 consultations were conducted with 616 patients over 25 years old, in the nutrition consultation, using the qualitative and quantitative individualized dieta...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.5.8648
更新日期:2015-05-01 00:00:00
abstract:AIMS:To assess, using a posterioritechniques, prevailing food consumption patterns of university students in Zamora and their association with food groups, in order to know how far can be away from a healthy diet, such as the Mediterranean diet. METHODS:Cross-sectional, descriptive and observational study of a represe...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1147
更新日期:2017-11-14 00:00:00
abstract:Introduction:The current COVID-19 pandemic mainly affects older people, those with obesity or other coexisting chronic diseases such as type-2 diabetes and high blood pressure. It has been observed that about 20 % of patients will require hospitalization, and some of them will need the support of invasive mechanical ve...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03180
更新日期:2020-07-13 00:00:00
abstract::As part of the nutritional survey of the Canary Islands (ENCA-1998), the concentrations in serum of Na, K, Ca and P were determined in 395 individuals representing the population of the Canary Islands. The concentrations were found to be within the reference intervals described for the healthy population. Differences ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:to determine if precipitation processes occur in parenteral nutrition solutions (PNs) with calcium gluconate and sodium glycerophosphate in the precipitation threshold limits of the Spanish SENPE/SEGHNP/SEFH 2008 consensus document of PN preparation. METHODS:seven PNs with different composition were prepared...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1861
更新日期:2018-10-05 00:00:00
abstract:INTRODUCTION:southern European, Middle Eastern, and North African countries bordering the Mediterranean share dietary habits characterized by moderation and a variety of foods, notably fruit and vegetables. These customs are becoming modified due to social and economic changes. An adequate intake of water and other dri...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9892
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To identify attitudinal determinants of fish consumption in Spain and Poland, and to discuss the potential impact of local healthy eating policies in the observed reported frequency of fish consumption. DESIGN:Repeated survey analysis , multivariate linear regression analysis. Data collected through a questi...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.1590/S0212-16112011000600031
更新日期:2011-11-01 00:00:00
abstract::Introducción: el trastorno por atracón o "Binge Eating Disorders" (BED) se caracteriza por el consumo de grandes cantidades de comida en un breve periodo de tiempo acompañado de una sensación de falta de control sobre la ingesta. El BED se relaciona con una alimentación poco equilibrada, contribuyendo a la aparición d...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.799
更新日期:2016-11-29 00:00:00
abstract:BACKGROUND:many endocrine-metabolic changes are involved in smoking. OBJECTIVES:to evaluate serum concentrations of inflammatory adipokines in smokers at baseline and after four months of treatment for smoking cessation. METHODS:the serum concentrations of inflammatory cytokines were evaluated in smokers and abstinen...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1548
更新日期:2018-02-27 00:00:00
abstract::In order to perform an in-depth study on food standards among school children and evaluate the effect of a nutritional educational programme on eating habits, an analysis was made of the data on the intake of foods over a period of 1,890 days, in 187 school children from 2 schools in the Leganés-Fuenlabrada area. The ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:GOAL:Once again, the NADYA-SENPE Working Group analysed the registered data of Home Enteral Nutrition (HEN) in our country, during the year 2000. MATERIAL AND METHODS:The data were collected through a closed questionnaire included on our web site (www.nadya-senpe.com). Apart from epidemiological information, the form ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Registering the ingestive activity of laboratory animals can be carried out by using electronic scales connected to personal computers, thus gathering data files that allow calculation of the daily ingestion standards. The ingestion parameters most often used in the standard analysis include the number, size, and dura...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:Chile has drastically altered eating patterns and physical activity. The main nutritional problem faced by Chilean society is overweight, which arises progressively from an early age. The aim of this study is to determine the nutritional status and compare fitness levels and fasting glucose in students. PAT...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.6.8932
更新日期:2015-06-01 00:00:00
abstract::The reliability of the information collected in dietary assessment can be affected by different factors. One of the main sources of error in dietary assessment is misreporting which encompass under- and overreporting. Underreporting of food intake is one of the major problems in the assessment of habitual dietary inta...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.sup3.8760
更新日期:2015-02-26 00:00:00
abstract::With obesity the amount of pro- and anti-inflammatory adipokines released is increased within the fat tissue. These molecules are implicated in many clinical manifestations of this pathology such as diabetes, arterial hypertension, or cardiovascular disease. At the first stage, the fat tissue of the obese patient beco...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2009-07-01 00:00:00
abstract::Se ha estudiado el efecto de la cocción en agua sobre la capacidad antioxidante y calidad sensorial de coliflor que previamente ha sido cortada, envasada en atmósfera modificada (5,7-2,3% de CO 2 y 17,6-19,7% de O 2 ) y almacenada a 5 oC durante 13 días, comparándola con la coliflor recién recolectada. Se ha observado...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.119
更新日期:2016-03-25 00:00:00