Abstract:
:The elderly are more often referred to nephrologists and questions about indications for renal biopsy are increasing. The vascular lesions that appear with aging make the diagnosis of additional nephropathy more difficult. The purpose of our study is to investigate the characteristics of renal biopsies in the elderly in order to evaluate the indications and their use in guiding specific therapeutic interventions. Patients over 70 years who underwent a renal biopsy between 2000 and 2007 in Rennes University Hospital were retrospectively analyzed for biopsy complications, clinical features, diagnosis, therapy and its complications, evolution and mortality. Among the 150 renal-biopsied patients, 60% had a glomerulopathy and 30% had nephrotic syndrome. Biopsy complications occurred in 3.3%. 64% of nephrotic patients received immunosuppressive treatment and 62% of them developed drug-associated complications. In the treated group, there was more remission and survival at day 1000 was improved. Renal biopsy may be indicated in the elderly, because it often gives a therapeutically useful diagnosis and complications are rare if contra-indications are respected. Kidney biopsy revealed histological diagnoses that were not usually suspected by the clinical presentation. In addition, immunosuppressive therapy did not alter the mortality rate, but did increase survival at 3 years.
journal_name
Arch Gerontol Geriatrjournal_title
Archives of gerontology and geriatricsauthors
Pinçon E,Rioux-Leclercq N,Frouget T,Le Pogamp P,Vigneau Cdoi
10.1016/j.archger.2010.03.006subject
Has Abstractpub_date
2010-11-01 00:00:00pages
e120-4issue
3eissn
0167-4943issn
1872-6976pii
S0167-4943(10)00081-6journal_volume
51pub_type
杂志文章abstract::The purpose of this cross-sectional study is to provide basic but essential information about how older cane users obtain their canes and how they use these canes for their daily mobility, since there is still lack of information on these areas. Ninety-three older (≥65 years old) subjects who use canes for daily activ...
journal_title:Archives of gerontology and geriatrics
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doi:10.1016/j.archger.2010.04.003
更新日期:2011-05-01 00:00:00
abstract::Serum concentrations of C-reactive protein (CRP), interleukin-6 (Il-6) and tumor necrosis factor-alpha (TNF-alpha), as well as body mass index (BMI) were measured in a series of 36 elderly subjects (18 males, 18 females) of mean age 76.8+/-4.5 years, in order to assess whether these parameters are involved in senile o...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
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journal_title:Archives of gerontology and geriatrics
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journal_title:Archives of gerontology and geriatrics
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2007.08.009
更新日期:2008-09-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 临床试验,杂志文章
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.09.003
更新日期:2012-09-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
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journal_title:Archives of gerontology and geriatrics
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
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更新日期:1988-03-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
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更新日期:1986-12-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,评审
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更新日期:2020-08-21 00:00:00
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journal_title:Archives of gerontology and geriatrics
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doi:10.1016/s0167-4943(01)00111-x
更新日期:2001-09-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2009.01.001
更新日期:2010-01-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.archger.2007.09.009
更新日期:2009-01-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.04.003
更新日期:2012-03-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,随机对照试验
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更新日期:2011-03-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2016.08.001
更新日期:2016-11-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
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doi:10.1016/j.archger.2011.02.018
更新日期:2012-01-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/s0167-4943(97)00016-2
更新日期:1997-11-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.07.003
更新日期:2012-07-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
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journal_title:Archives of gerontology and geriatrics
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更新日期:2017-09-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2009.08.004
更新日期:2010-07-01 00:00:00
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journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00