Abstract：
BACKGROUND:Age is an important factor in determining prognosis following severe head injury (SHI), although mortality in patients > or =65 years is poorly reported. The aim of this study was to document mortality in patients with SHI > or =65 years. METHODS:A retrospective analysis of prospectively collected data from the TARN (Trauma Audit and Research Network) database (1996-2004) was performed. Six hundred and sixty-nine patients aged > or =65 with a GCS <9 after a head injury were identified, and mortality at 3 months was recorded. FINDINGS:Mortality was 71% in 65- to 70-year-old patients (n = 137) (CI, 64-79), 75% for patients aged 70-75 years (n = 147) (CI, 68-82), 85% in patients aged 75-80 years (n = 160) (79-91), and 87% for patients >80 years (n = 225) (CI, 83-91). Mortality for all patients > or =65 years with a GCS 3-5 was >80%. A better outcome was observed in patients with a GCS = 6-8 [65-70 years, 47% (CI, 30-64); 70-75 years, 56% (CI, 43-69); 75-80 years, 73% (CI, 62-85); >80 years, 79% (CI, 70-87)]. CONCLUSIONS:SHI-related mortality continues to increase with age. Overall, these data support a conservative approach to the severely head-injured elderly patient; however, patients presenting with a GCS = 6-8 and below the age of 75 may represent a group where more aggressive therapy may be indicated.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Patel HC,Bouamra O,Woodford M,Yates DW,Lecky FEdoi
10.1007/s00701-010-0666-xsubject
Has Abstractpub_date
2010-08-01 00:00:00pages
1353-7; discussion 1357issue
8eissn
0001-6268issn
0942-0940journal_volume
152pub_type
杂志文章abstract：:Forty-two patients with 44 cephaloceles treated between 1966 and 1993 are presented. Eighteen lesions were occipital, 2 parietal, 1 at the anterior fontanelle, 11 sincipital, and 12 basal. In recent years computerized tomography (CT) and magnetic resonance imaging (MRI) provided better information on the site and natu...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01417678
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Chronic subdural haematomas (cSDHs) have shown an increasing incidence in an ageing population over the last 20 years, while unacceptable recurrence rates of up to 30 % persist. The recurrence rate of cSDH seems to be related to the excessive neoangiogenesis in the parietal membrane, which is mediated via va...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00701-016-2949-3
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Giant intracranial aneurysms of the posterior circulation (GPCirA) are rare entities compressing the brainstem and adjacent structures. Previous evidence has shown that the amount of brainstem shift away from the cranial base is not associated with neurological deficits. This raises the question whether othe...
journal_title：Acta neurochirurgica
pub_type： 临床试验,杂志文章
doi：10.1007/s00701-019-04016-x
更新日期：2019-09-01 00:00:00
abstract：:Traditional clinical outcome measures for the treatment of Parkinson's disease (PD) have focused on motor function and activities of daily living. However, in the past decade there has been a new emphasis on the use of health related quality of life (HRQOL) measures for translating how a patient's response to treatmen...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010070090
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Nicardipine prolonged release implants (NPRI) have been shown to decrease the incidence of cerebral vasospasm and infarcts significantly in patients after aneurysmal subarachnoid haemorrhage (SAH) following microsurgical clipping. Yet, the comparison with results after endovascular coiling is lacking. This s...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-011-1129-8
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Corrective craniosynostosis surgery is often associated with a large amount of blood loss and metabolic disturbances. In the present study, we investigated the severity, duration of metabolic disturbances, and causal risk factors in infants. METHODS:A retrospective analysis was performed of 36 infants who u...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2441-5
更新日期：2015-07-01 00:00:00
abstract：:Lesions generated by the passage of micro-needles through vessel walls are of concern because any lesion may significantly alter hemodynamics of an anastomosis. To study this problem, three different needles were tested on the exposed carotid arteries of 30 rats: the 100 mu taper point, the 100 mu cutting point, and t...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01402308
更新日期：1985-01-01 00:00:00
abstract：:Patients with multiple intracranial aneurysms present a great challenge to neurosurgical practice. The presence of one or more additional aneurysms, whether recognized or unrecognized, along with the source of the haemorrhage profoundly changes the outcome. It also alters the timing and strategy of surgery. In this st...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01456314
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:The external ventricular drain (EVD) placement is one of the most common neurosurgical procedures. This operation is performed by freehand technique in the majority of cases; therefore, the operator's experience plays an important role in success and possible morbidity of this procedure. OBJECTIVE:To evalua...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-020-04671-5
更新日期：2021-01-06 00:00:00
abstract：:We retrospectively analysed 13 patients (pts.) treated at the University of Tübingen from 1985 to 1993 to evaluate the results of radiation therapy (XRT) given as an adjuvant to totally or subtotally resected meningiomas. The overall survival was 38% at five years with a probability of relapse of 50% at this time. Rec...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF02187764
更新日期：1995-01-01 00:00:00
abstract：:Despite a body of evidence showing that various neurotrophic factors support the survival of nerve cells and stimulate axonal outgrowth, doubt remains about their optimal site of application as well as the more compelling question of what clinical benefit, if any, they would confer. Ciliary neurotrophic factor (CNTF) ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-005-0631-2
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:The association between external ventricular drainage (EVD) and aneurysm rerupture is still a controversial issue. We performed a systematic review and meta-analysis of published series reporting data of EVD placement in aneurysmal subarachnoid hemorrhage (SAH) with the aim to evaluate the relationship betwe...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00701-017-3124-1
更新日期：2017-04-01 00:00:00
abstract：:Retroclival arachnoid cysts are rarely reported. A 40-year-old woman had a sudden onset of occipitocervical pain. Magnetic resonance imaging (MRI) revealed a cystic mass lesion located in the retroclival region and complicated with intracystic haemorrhage. At operation, by a right lateral suboccipital approach, an old...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-009-0381-7
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:The authors applied a scaffold-free osteogenic three-dimensional (3D) graft made of adipose-derived mesenchymal stem cells (AMSCs) in patients undergoing minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). METHODS:Three patients (two patients and one patient with 1 and 2 levels, respectivel...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-016-3051-6
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Subarachnoid hemorrhage (SAH) has been recognized as a risk factor for ventriculostomy-related infections (VRI). In addition to the hemorrhagic cerebrospinal fluid (CSF), the potential need for prolonged catheterization may contribute to the increased CSF infection rate in this population. The use of antibio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1276-6
更新日期：2012-04-01 00:00:00
abstract：:Migration of the catheter tip of a ventriculoperitoneal shunt (VPS) through a patent processus vaginalis (PV) has seldom being reported. In this series, we analyzed all cases of inguinoscrotal migration of an VPS catheter at our center. Between 1975 and 2015, 295 VPS insertions were performed. In seven infants (2.3%),...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-017-3243-8
更新日期：2017-08-01 00:00:00
abstract：:The most frequent sequelae after severe brain injury include changes in personality traits, disturbances of emotional behaviour and impairment of cognitive functions. In particular, emotional changes and/or verbal and non verbal dysfunctions were found in patients with bilateral or unilateral temporal lobe lesions. Th...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01405688
更新日期：1991-01-01 00:00:00
abstract：:The brain-type isoenzyme of creatine kinase was determined in serum (S) and cerebrospinal fluid (CSF) in 37 patients with severe head injury, and a correlation was made with the Glasgow coma score and Glasgow outcome score. All patients with normal S-CKBB and CSF-CKBB activities had a coma score of 15, i.e., no neurol...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01418476
更新日期：1985-01-01 00:00:00
abstract：OBJECT:Hydrocephalus is characterised by elevated intracranial pressure (ICP) and gives rise to brain damage. The aim of this study was to investigate the significance of brain specific proteins as markers in the evaluation of brain damage in hydrocephalus. Therefore we determined the levels of four brain specific prot...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-002-1019-1
更新日期：2003-01-01 00:00:00
abstract：:Three cases of surgically treated non-neoplastic diseases of the sella (two arachnoid cysts and one empty sella) are reported. All three patients had visual deficits but no gross endocrine disturbances. The study of these three clinical cases and an analysis of the relevant literature suggest a possible unitary hypoth...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01401097
更新日期：1977-01-01 00:00:00
abstract：:Being motor nerves neurinomas originating from ocular nerves are very rare, unless associated with neurofibromatosis. Authors describe two cases of oculomotor nerve i.e. third nerve, Schwann cell tumours. One of them presented as a cavernous sinus mass in a middle aged lady while the other was a middle aged man with a...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010050229
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Before operating on 130 patients with pituitary disorders, we evaluated their bone window CT images sliced parallel to the transnasal surgical route to assess the surgical anatomy of the nasal cavity for transnasal surgery. METHODS:High resolution bone window CT was performed in 3- to 5-mm slices parallel to...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-002-1043-1
更新日期：2003-02-01 00:00:00
abstract：INTRODUCTION:Patients with thalamic hemorrhage, depressed level of consciousness and/or signs of elevated intracranial pressure may be treated with neurocritical care (NCC) and external ventricular drainage (EVD) for release of cerebrospinal fluid. METHODS:Forty-three patients with thalamic hemorrhage treated with NCC...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1871-1
更新日期：2013-11-01 00:00:00
abstract：:The authors describe a case of a post-traumatic subdural haematoma with an unusual evolution in two phases, one slow, the other very rapid. The rapidity of the evolution was caused by the rupture of a cortical dural artery, shown angiographically. ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01401797
更新日期：1979-01-01 00:00:00
abstract：BACKGROUND:Anterior cervical decompression and fusion (ACDF) may necessitate acute and late re-operations. Published long-term follow studies after ACDF are scarce. OBJECTIVE:Our goal was to give a detailed description of early and late re-operations after ACDF in an 11-year follow-up. METHODS:We retrospectively anal...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1563-2
更新日期：2013-02-01 00:00:00
abstract：:In 131 cases of craniocerebral trauma it was shown in what respect definite changes in the lungs, demonstrated by clinical course, radiographs and blood gas analyses, occurred in proportion to the severity of the trauma. The causes of these changes were considered and the possibility of complicating the course of the ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01405745
更新日期：1976-01-01 00:00:00
abstract：:The authors report on four unusual cases of chronic adult hydrocephalus extracted from a large personal series of patients with hydrocephalic dementia. A syndrome resembling that of normal pressure hydrocephalus was due to the following aetiologies in these patients: Paget's disease of the skull, unruptured cerebral a...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01808923
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND:The mechanisms underlying post-extracranial to intracranial (EC-IC) bypass neurocognitive changes are poorly understood. METHODS:Data from 55 patients who underwent a unilateral EC-IC bypass for atherosclerotic internal carotid artery (ICA)/middle cerebral artery (MCA) steno-occlusive disease were retrospec...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2620-4
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:It is essential to have easy to use, reliable tools to assess and compare facial function for clinical records, audit and research purposes. In this study, two different techniques were examined, Hand held calipers (HHC, as described by Burres), and computerised analysis of digital photographs (CAOP) using A...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-006-0904-4
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Close relatives (CR) of patients with severe traumatic brain injury (TBI) and high-grade subarachnoid hemorrhage (SAH) suffer extraordinary distress during the treatment: Distress may lead to persisting mental illness symptoms within the spectrum of post-traumatic stress disorder (PTSD), anxiety disorders, a...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2470-0
更新日期：2015-09-01 00:00:00
