Paracoccidioidomycosis: a series of 66 patients with oral lesions from an endemic area.

Abstract:

:Paracoccidioidomycosis (PCM) is the most important systemic mycosis in Latin America. It has been regarded as a multifocal disease, with oral lesions as the prominent feature. To provide useful information concerning the diagnosis and management of the disease, this study describes demographic and clinical data from the medical records of a consecutive series of 66 Brazilian patients from an endemic area, evaluated in a referral centre for oral diagnosis. In this sample of patients, there was a predominance of middle-aged male patients, who were primarily rural workers. Chronic multifocal disease was prevalent, with lesions also detected in the lungs, lymph nodes, skin or adrenal glands. Most of the cases presented with lesions at the gingival mucosa followed by the palate and lips; these conditions occurring in the oral cavity were frequently associated with pain. Importantly, most of the patients sought professional care for oral lesions. The diagnosis was obtained through exfoliative cytology and/or biopsy of the oral lesions. Medical treatment was effective, and there were no mortalities in the sample. The present findings not only confirm the importance of oral lesions in the diagnosis and management of PCM but also illustrate that questions still remain unclear, such as the possibility of direct inoculation of the fungus onto oral tissues.

journal_name

Mycoses

journal_title

Mycoses

authors

Brazão-Silva MT,Andrade MF,Franco T,Ribeiro RI,Silva Wdos S,Faria G,Faria PR,Cardoso SV,Loyola AM

doi

10.1111/j.1439-0507.2010.01873.x

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

e189-95

issue

4

eissn

0933-7407

issn

1439-0507

pii

MYC1873

journal_volume

54

pub_type

杂志文章

相关文献

MYCOSES文献大全
  • Cunninghamella pneumonia in postbone marrow transplant patient: first case report from India.

    abstract::Cunninghamella bertholletiae, a rare causative agent of mycosis among immunocompromised patients has been reported with increased frequency from western countries in recent years. We report a case of C. bertholletiae pulmonary infection in a 42-year-old male patient who developed graft-vs.-host disease following bone ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01139.x

    authors: Sivakumar S,Mathews MS,George B

    更新日期:2005-09-01 00:00:00

  • Molecular diagnostics of clinical strains of filamentous Basidiomycetes.

    abstract::Eleven clinical and veterinary strains of filamentous Basidiomycetes were compared with 15 reference strains representing the orders Aphyllophorales and Agaricales. The methods used were restriction analysis of small subunit (18S) (SSU) rDNA and internal transcribed spacers (ITS) 1 and 2 and variable domain 9 (V9)-ITS...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1998.tb00321.x

    authors: de Hoog GS,Gerrits van den Ende AH

    更新日期:1998-05-01 00:00:00

  • Multicentric genetic study of Candida albicans isolates from non-neutropenic patients using MLEE typing: population structure and mode of reproduction.

    abstract::A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus ...

    journal_title:Mycoses

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.1439-0507.2000.00552.x

    authors: Arnavielhe S,De Meeüs T,Blancard A,Mallié M,Renaud F,Bastide JM

    更新日期:2000-01-01 00:00:00

  • The role of Candida infections as an adverse effect upon head and neck cancer patients undergoing therapeutic radiation and the effect of antimycotic treatment.

    abstract::Oral, pharyngeal and esophageal infections caused by Candida species occur very frequently when it comes to radiation therapy for head and neck cancer. In clinical terms oral candidosis is most often characterized by pseudomembranes or erythema. The erythematous form of oral candidosis has in particular to be distingu...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1989.tb02308.x

    authors: Poland JM

    更新日期:1989-01-01 00:00:00

  • Studies on mycotic keratitis.

    abstract::One hundred and fifty cases of corneal ulcers from the Government Ophthalmic Hospital, Madras, were investigated during 1980-1982 for the mycoflora. 68 cases (45%) were positive for fungi, comprising species of Aspergillus (36 cases), Penicillium, Fusarium (8 cases each), Curvularia (4 cases), Candida albicans and Muc...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1989.tb02183.x

    authors: Sundaram BM,Badrinath S,Subramanian S

    更新日期:1989-11-01 00:00:00

  • Identification of an invasive infection of R. oryzae in a haematological patient using a molecular technique.

    abstract::We report a case of cerebral mucormycosis in a 28-year-old male who was affected by chronic myeloid leukaemia and underwent allogeneic bone marrow transplantation. Nine months post-transplantation, he was admitted to the hospital with fever, bilateral eyelid oedema and neutropenia. X-ray analysis showed numerous areas...

    journal_title:Mycoses

    pub_type: 信件

    doi:10.1111/j.1439-0507.2009.01689.x

    authors: Cavrini F,Stanzani M,Liguori G,Sambri V

    更新日期:2010-05-01 00:00:00

  • The changing trends and profile of pneumocystosis mortality in the United States, 1999-2014.

    abstract::Pneumocystosis (PCP) mortality in the U.S. has received less attention in recent years. This study describes recent trends in mortality and the estimated burden of PCP in the U.S., using the national multiple cause of death data during 1999-2014. PCP mortality rates were calculated for age, sex, race and year. Demogra...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12636

    authors: Wickramasekaran RN,Jewell MP,Sorvillo F,Kuo T

    更新日期:2017-09-01 00:00:00

  • Efficacy of caspofungin in invasive candidiasis and candidemia--de-escalation strategy.

    abstract::Candida species constitute the majority of nosocomial fungal pathogens in non-neutropenic patients. Candida infections are still connected with substantial mortality. Recent epidemiological observations indicate a shift to non-albicans species, especially because of a rise of infections caused by C. glabrata, which fr...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2008.01527.x

    authors: Lichtenstern C,Nguyen TH,Schemmer P,Hoppe-Tichy T,Weigand MA

    更新日期:2008-01-01 00:00:00

  • Impact of invasive aspergillosis occurring during first induction therapy on outcome of acute myeloid leukaemia (SEIFEM-12B study).

    abstract:BACKGROUND:Acute myeloid leukaemia (AML) patients are at high risk of invasive aspergillosis (IA) after first induction chemotherapy (CHT). Although IA risk factors have been identified, few data are available on impact of IA, occurring during induction phase, on overall AML outcome. PATIENTS AND RESULTS:The end point...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13147

    authors: Candoni A,Farina F,Perruccio K,Di Blasi R,Criscuolo M,Cattaneo C,Delia M,Zannier ME,Dragonetti G,Fanci R,Martino B,Del Principe MI,Fianchi L,Vianelli N,Chierichini A,Garzia M,Petruzzellis G,Nadali G,Verga L,Busca A

    更新日期:2020-10-01 00:00:00

  • Non-response to fluconazole maintenance treatment (ReCiDiF regimen) for recurrent vulvovaginal candidosis is not related to impaired glucose metabolism.

    abstract::Is non-response to maintenance treatment for recurrent vulvovaginal candidosis (RCVV) related to the impaired glucose metabolism? In the ReCiDiF trial, women with RCVV were given a degressive regimen with fluconazole according to their clinical, microscopic and mycologic response. Data obtained from optimal, suboptima...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12626

    authors: Grinceviciene S,Bellen G,Ruban K,Donders G

    更新日期:2017-08-01 00:00:00

  • Oral clioquinol is effective in the treatment of a fly model of Candida systemic infection.

    abstract:BACKGROUND:Clioquinol was used in the 1950s-1970s as antimicrobial but its oral formulations were withdrawn from the market due to suspected neurotoxicity. Currently, there is possibility of repositioning of oral clioquinol formulations. OBJECTIVES:To evaluate the antifungal activity and toxicological parameters of cl...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12888

    authors: Pippi B,Merkel S,Staudt KJ,Teixeira ML,de Araújo BV,Zanette RA,Andrade SF,Fuentefria AM

    更新日期:2019-05-01 00:00:00

  • Cryptococcosis: the 1981-2000 epidemic.

    abstract::The annual incidence of cryptococcosis during 1981-2000 was determined in subscribers of a large integrated health care program in Northern California and in those among them who were HIV positive. The incidence of cryptococcosis had been measured in this setting in the previous decade. The 20-year incidence per milli...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2004.01082.x

    authors: Friedman GD,Jeffrey Fessel W,Udaltsova NV,Hurley LB

    更新日期:2005-03-01 00:00:00

  • Preparation of antigens from Trichophyton mentagrophytes using a new semi-solid culture medium and their characterization by SDS-PAGE and immunological techniques.

    abstract::A new semi-solid culture medium was developed by substituting the agar in Sabouraud glucose medium by Lutrol FC 127 (BASF, Ludwigshafen, Germany). This culture medium can be liquefied by cooling it down from the incubation temperature to 5-10 degrees C, thus allowing the full harvest of fungal mycelium without any con...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1992.tb00893.x

    authors: Garg AP,Müller J

    更新日期:1992-11-01 00:00:00

  • Onychomycosis is no longer a rare finding in children.

    abstract::Onychomycosis was considered uncommon in children. This survey was carried out to estimate the frequency of fungal nail infections in children and adolescents (0-18 years of age) attending our clinic in the last decade and gain more insight into the aetiology and clinics of this entity in the paediatric age group. Thi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01186.x

    authors: Lange M,Roszkiewicz J,Szczerkowska-Dobosz A,Jasiel-Walikowska E,Bykowska B

    更新日期:2006-01-01 00:00:00

  • Antifungal activity of some 2,2':5',2"-terthiophene derivatives.

    abstract::The dermatophyte Microsporum cookei Ajello was treated with nine new natural and synthetic 2,2':5',2"-terthiophenes to determine their possible antifungal activity. In the dark the thiophenes were inactive, while when photoactivated with UV-A they induced a remarkable reduction in the growth rate of the fungus. The on...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.1994.37.9-10.377

    authors: Mares D,Romagnoli C,Rossi R,Carpita A,Ciofalo M,Bruni A

    更新日期:1994-09-01 00:00:00

  • Extrusion of fluorescein diacetate by multidrug-resistant Candida albicans.

    abstract::Over-expression of multidrug efflux transporters causes Candida albicans cells to be resistant to azole antifungal agents. There are several kinds of indicator for multidrug resistance (MDR) phenotype of higher eukaryotic cells. Calcein AM is a prefluorochrome that is known as a substrate for multidrug efflux transpor...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1046/j.1439-0507.2001.00666.x

    authors: Yang HC,Mikami Y,Imai T,Taguchi H,Nishimura K,Miyaji M,Branchini ML

    更新日期:2001-11-01 00:00:00

  • [Prophylaxis and therapy of fungal infections in oncology].

    abstract::The observation of a considerable incidence of fungal infections in oncology patients has promoted a large number of studies both on prophylaxis and treatment in this patient group. Trials using triazoles, especially fluconazole, have shown effect in preventing fungal infections. In neutropenic patients, their role in...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1995.tb00484.x

    authors: Schuler U,Mölle M,Ehninger G

    更新日期:1995-01-01 00:00:00

  • Screening for asymptomatic scalp carriage in household contacts of patients with tinea capitis during 1997-2011: a retrospective hospital-based study.

    abstract::For anthropophilic tinea capitis (TC), household spread and asymptomatic scalp carriage (ASC) is considered an important route of transmission and incomplete clearance. To investigate ASC in household contacts of patients diagnosed with TC in a tertiary hospital in Athens, Greece, we retrospectively reviewed the medic...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12166

    authors: Dessinioti C,Papadogeorgaki E,Athanasopoulou V,Antoniou C,Stratigos AJ

    更新日期:2014-06-01 00:00:00

  • Superficial mycoses due to Trichophyton violaceum in Athens, Greece: a 15-year retrospective study.

    abstract::This is a retrospective study on the superficial mycoses due to Trichophyton violaceum in the greater Athens area for the last 15 years - 1989-2003. During this period 104 patients were found to have an infection due to T. violaceum- an incidence rate of 0.75% of all dermatophytosis. Of the patients 59 were Greeks, 15...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01159.x

    authors: Frangoulis E,Papadogeorgakis H,Athanasopoulou B,Katsambas A

    更新日期:2005-11-01 00:00:00

  • Clinical and pharmacoeconomic evaluation of antifungal prophylaxis with continuous micafungin in patients undergoing allogeneic stem cell transplantation: A six-year cohort analysis.

    abstract:BACKGROUND:Patients undergoing allogeneic stem cell transplantation (aSCT) are at high risk to develop an invasive fungal disease (IFD). Optimisation of antifungal prophylaxis strategies may improve patient outcomes and reduce treatment costs. OBJECTIVES:To analyse the clinical and economical impact of using continuou...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13232

    authors: Wingen-Heimann SM,Cornely OA,J G T Vehreschild M,Wisplinghoff H,Franke B,Schons M,von Bergwelt-Baildon M,Scheid C,Vehreschild JJ

    更新日期:2020-12-22 00:00:00

  • Antifungal susceptibility of Candida species isolated from patients with candidemia in southern Taiwan, 2007-2012: impact of new antifungal breakpoints.

    abstract::The Clinical and Laboratory Standard Institute (CLSI) revised the clinical breakpoints (CBPs) for the azoles and echinocandins against Candida species in 2012. We aimed to report the epidemiology of candidemia and antifungal susceptibility of Candida species and evaluate the impact of new CBPs on antifungal susceptibi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12553

    authors: Chen YC,Kuo SF,Chen FJ,Lee CH

    更新日期:2017-02-01 00:00:00

  • Clinical and pharmacokinetic investigations of oral terbinafine in patients with tinea unguium.

    abstract::A clinical trial of once-daily administration of a 125-mg tablet of terbinafine, an oral antimycotic agent, was performed on patients with tinea unguium to evaluate its efficacy, safety, possible side-effects and its incorporation into nails and hair. Thirty-four patients were recruited into the study. For the statist...

    journal_title:Mycoses

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1439-0507.1995.tb00037.x

    authors: Matsumoto T,Tanuma H,Kaneko S,Takasu H,Nishiyama S

    更新日期:1995-03-01 00:00:00

  • Oral candidosis in patients with removable dentures.

    abstract::The prevalence of Candida species with and without denture-related stomatitis were evaluated in 167 Jordanian patients. The study revealed that 47 (28%) of the patients with denture-related stomatitis were colonized with Candida species (clinical group). Candida albicans was responsible for most cases of denture-relat...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1046/j.1439-0507.2003.00871.x

    authors: Dar-Odeh NS,Shehabi AA

    更新日期:2003-06-01 00:00:00

  • Molecular detection and characterisation of fungal heat shock protein 60.

    abstract::Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was inves...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01933.x

    authors: Raggam RB,Salzer HJ,Marth E,Heiling B,Paulitsch AH,Buzina W

    更新日期:2011-09-01 00:00:00

  • Comparative evaluation of pan-fungal real-time PCR, galactomannan and (1-3)-β-D-glucan assay for invasive fungal infection in paediatric cancer patients.

    abstract::Limited specific data and investigations are available for the diagnosis of Invasive Fungal Infection (IFI) in paediatrics cancer patients. Three non-invasive tests; Platelia Aspergillus EIA for galactomannan (GM), β-D-glucan (BDG) assay and pan-fungal real-time PCR for fungal DNA in blood were evaluated. One hundred ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12584

    authors: Gupta P,Ahmad A,Khare V,Kumar A,Banerjee G,Verma N,Singh M

    更新日期:2017-04-01 00:00:00

  • Vulvovaginitis due to Candida glabrata. An emerging problem.

    abstract::A review is presented of the emerging problem of resistant and chronic vaginitis due to Candida glabrata. Although accurate numbers are lacking, several investigators report encountering increased numbers of women with vaginitis due to C. glabrata. Possible reasons for this apparent increase are discussed. Risk factor...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.1998.tb00594.x

    authors: Sobel JD

    更新日期:1998-01-01 00:00:00

  • Genetic re-identification and antifungal susceptibility testing of Aspergillus section Nigri strains of the BCCM/IHEM collection.

    abstract::Black Aspergilli are widely distributed in the environment and are frequently reported as causative agents of different types of mycoses. Many taxonomical revisions have been made, and presently 19 different species are accepted. In this study we (re-) identified 123 strains of the Aspergillus niger group of the BCCM/...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2011.02049.x

    authors: Hendrickx M,Beguin H,Detandt M

    更新日期:2012-03-01 00:00:00

  • Effect of reducing agents on proteolytic and keratinolytic activity of enzymes of Microsporum gypseum.

    abstract::The effect of sodium sulphite, cysteine, glutathione, mercaptoethanol and dithioerythritol (0.1-10 mmol l-1) on the activity of proteases of Microsporum gypseum was studied using azocasein, cross-linked bovine serum albumin and keratin as substrates. With the substrate without disulphide bonds (casein) no stimulation ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1992.tb00892.x

    authors: Kunert J

    更新日期:1992-11-01 00:00:00

  • Geographical distribution of mycetoma cases in senegal over a period of 18 years.

    abstract:BACKGROUND:Mycetoma is a pathological process in which fungal or actinomycotic agents of exogenous origin produce grains. In the absence of data on the global burden, it is important to map mycetoma cases, which are useful to implement control strategies. OBJECTIVE:The objective of this study was to map mycetoma cases...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13037

    authors: Badiane AS,Ndiaye M,Diongue K,Diallo MA,Seck MC,Ndiaye D

    更新日期:2020-03-01 00:00:00

  • Low level of antifungal resistance of Candida glabrata blood isolates in Turkey: Fluconazole minimum inhibitory concentration and FKS mutations can predict therapeutic failure.

    abstract:BACKGROUND:Candida glabrata is the third leading cause of candidaemia in Turkey; however, the data regarding antifungal resistance mechanisms and genotypic diversity in association with their clinical implication are limited. OBJECTIVES:To assess genotypic diversity, antifungal susceptibility and mechanisms of drug re...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13104

    authors: Arastehfar A,Daneshnia F,Salehi M,Yaşar M,Hoşbul T,Ilkit M,Pan W,Hagen F,Arslan N,Türk-Dağı H,Hilmioğlu-Polat S,Perlin DS,Lass-Flörl C

    更新日期:2020-09-01 00:00:00