Abstract:
BACKGROUND:The ability of 64-slice computed tomography (CT) angiography to differentiate plaque types remains unclear. We evaluated whether the density of noncalcified coronary plaques by 64-slice CT angiography correlates with plaque components assessed by integrated backscatter intravascular ultrasound (IB-IVUS). METHODS:Eighty-six patients [stable angina/acute coronary syndrome (ACS) 67/19, mean age 62+/-11 years] who showed significant coronary artery stenosis (> or =50% diameter stenosis) by 64-slice CT angiography underwent coronary angiography and were evaluated using IB-IVUS. RESULTS:A total of 92 noncalcified coronary plaques on CT angiography were evaluated with IB-IVUS. There was a positive correlation between CT density and calcified tissue content (r=0.41, P<0.001). However, the CT density of plaques did not correlate with other tissue components. Patients with ACS showed more lipid (43.1+/-13.2 vs. 35.8+/-13.5, P=0.03) and less soft fibrous tissue (50.5+/-11.7 vs. 56.5+/-12.0, P=0.05) by IB-IVUS than those with stable angina. However, the mean CT density of plaques in ACS was not different from that in stable angina (140.6+/-88.5 vs. 113.1+/-80.9, P=0.19). CONCLUSION:Except for calcified tissue, CT angiography failed to differentiate plaque types of noncalcified tissue. Therefore, the role of 64-slice CT angiography in identifying lipid-rich plaques remains limited.
journal_name
Coron Artery Disjournal_title
Coronary artery diseaseauthors
Yang WI,Hur J,Ko YG,Choi BW,Kim JS,Choi D,Ha JW,Hong MK,Jang Y,Chung N,Shim WH,Cho SYdoi
10.1097/MCA.0b013e32833578f4subject
Has Abstractpub_date
2010-05-01 00:00:00pages
168-74issue
3eissn
0954-6928issn
1473-5830journal_volume
21pub_type
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e32832fe5d5
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abstract:OBJECTIVES:The long-term clinical impact of polymer-free sirolimus-eluting stents (PF-SES) in unselected patients undergoing percutaneous coronary intervention (PCI) still remains poorly investigated. We studied the long-term clinical impact of PF-SES in a large cohort of unselected patients receiving PCI therapy at tw...
journal_title:Coronary artery disease
pub_type: 杂志文章,多中心研究
doi:10.1097/MCA.0000000000000378
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abstract:BACKGROUND:The transradial approach has gained increasing popularity for elective percutaneous coronary intervention. However, the safety and feasibility of transradial coronary intervention (TRI) in acute myocardial infarction (AMI) remains uncertain. Hence, a meta-analysis of randomized trials was performed to compar...
journal_title:Coronary artery disease
pub_type: 杂志文章,meta分析
doi:10.1097/MCA.0b013e3283526a9d
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abstract::Endothelial dysfunction not only precedes the development of significant coronary artery stenosis, it has also been identified as a general phenomenon predicting future cardiovascular events in patients who are at risk. As regular physical activity as a part of a multifactorial intervention has been shown to affect sy...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-200605000-00003
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Nitroglycerin (NTG) is known to increase the blood supply to the myocardium, and would thus increase the delivery of a perfusional tracer such as sestamibi (MIBI) to the tissue. The latter, in turn, would take up and concentrate the tracer to a greater extent than in basal conditions only if energy-dependent...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199612000-00002
更新日期:1996-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199305000-00007
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200412000-00006
更新日期:2004-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3281689a2c
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
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journal_title:Coronary artery disease
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pub_type: 杂志文章,多中心研究
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更新日期:2013-01-01 00:00:00
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283608c32
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:We aimed to examine the association between plasminogen activator inhibitor-1 (PAI-1) genetic polymorphism and early spontaneous recanalization in patients presenting with acute ST-elevation myocardial infarction. METHODS:Patients admitted to our emergency department with ST-elevation myocardial infarction ...
journal_title:Coronary artery disease
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doi:10.1097/MCA.0b013e32835d7633
更新日期:2013-05-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,随机对照试验
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更新日期:2012-03-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199912000-00010
更新日期:1999-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3282f40dd5
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Measurement of antibodies to oxidized low-density lipoprotein (AB-oxLDL) has been proposed as a way of identifying individuals at risk for cardiovascular disease beyond the determination of LDL cholesterol (LDL-c) alone. While this hypothesis is appealing, evidence that AB-oxLDL is a risk factor independent ...
journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199702000-00006
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
pub_type: 杂志文章
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更新日期:2015-05-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200202000-00008
更新日期:2002-02-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200012000-00008
更新日期:2000-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e328035f8ae
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Free-radical generation after successful thrombolysis in acute myocardial infarction may jeopardize ischaemic but viable myocardium, thus limiting the optimal benefits of reperfusion. METHODS:Circulating free-radical activity was assessed in 25 consecutive patients with acute myocardial infarction. Those wh...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199309000-00003
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e328330d541
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare the outcome for men and women with chest pain or other symptoms suggestive of acute myocardial infarction (AMI) and a normal ECG on admission. METHODS:All patients who presented to our emergency room over a 21-month period with chest pain or other symptoms suggestive of ...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e32834df573
更新日期:2012-01-01 00:00:00