Abstract:
:Several 4-arylidene-2-phenyl-1-(2,4,5-trichlorophenyl)-1H-imidazol-5(4H)-ones (4a-q), N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-4-chlorobenzamides (5a-o) and N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-2,4-dichlorobenzamides (6a-m) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against gram (+)ve and gram (-)ve bacteria and also on different strains of fungi. Introduction of OH, OCH(3), NO(2), Cl and Br groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.
journal_name
Indian J Pharm Scijournal_title
Indian journal of pharmaceutical sciencesauthors
Desai NC,Bhavsar AM,Baldaniya BBdoi
10.4103/0250-474X.51953subject
Has Abstractpub_date
2009-01-01 00:00:00pages
90-4issue
1eissn
0250-474Xissn
1998-3743journal_volume
71pub_type
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