Abstract:
:Mate (Ilex paraguariensis A. St. Hil.) is a raw material used to prepare popular beverages in South America, whose healthy effects have been pointed out. The leaves and stems of mate contain a complex assemblage of saponins, mainly ursolic acid and oleanolic acid glycosides, and their quantification presents difficulties such as weak cromophorous sites and interference of other compounds. On the other hand, the sugar moieties are a chief character that distinguishes them. We developed and validated a high-performance liquid chromatography method using a refractometer detector for quantifying the major saponins in extractive solution of mate leaves. The validation indicates the suitability of the method, presenting linearity in the concentration range between 102.5 to 854.0 microg/mL to matesaponin 1 and between 103.0 to 515.0 microg/mL to matesaponin 3. The repeatability coefficient of variation was 4.70% and 6.61% for matesaponin 1 and matesaponin 3, respectively. The inter-day coefficient of variation was 6.77% and 7.79% for matesaponin 1 and matesaponin 3, respectively. The analysis of plants from Brazilian States Mato Grosso do Sul and Rio Grande do Sul showed the predominance of matesaponins 1, 2, and 3 in the corresponding extractive solution. The sum of these three saponins ranged between 3 and 10 mg/g for mature leaves in the majority of sampled plants.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Coelho GC,Gnoatto SB,Bassani VL,Schenkel EPdoi
10.1089/jmf.2009.0046subject
Has Abstractpub_date
2010-04-01 00:00:00pages
439-43issue
2eissn
1096-620Xissn
1557-7600journal_volume
13pub_type
杂志文章abstract::3,3'-diindolylmethane is a major in vivo metabolite of indole-3-carbinol, a bioactive compound found in cruciferous vegetables. Although 3,3'-diindolylmethane has been implicated to possess antitumorigenic and anti-inflammatory properties, the effect of 3,3'-diindolylmethane on adipogenesis has not been explored previ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2016.0165
更新日期:2017-07-01 00:00:00
abstract::Dietary flavonoids have various biological functions, and there is increasing evidence that reduced prevalence and severity of allergic reactions are associated with the intake of flavonoids. Among natural flavonoids, apigenin is a potent anti-inflammatory agent. However, the mechanisms of apigenin's effect remain unc...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2009.1229
更新日期:2010-04-01 00:00:00
abstract::The effects of the turmeric ethyl acetate fraction (TEF) from the methanolic extract from Curcuma longa L. on lipid metabolism and underlying mechanisms of lipolysis were investigated in 3T3-L1 adipocytes. The intracellular lipid droplets were stained with Oil red O dye and quantified. Compared to the control, lipid a...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2009.1276
更新日期:2010-04-01 00:00:00
abstract::Soy products are mainly composed of proteins, phytochemicals such as isoflavones, soy lipids, and carbohydrates. It is unclear whether an individual component alone or a combined effect of multiple bioactive compounds contributes to the beneficial properties of soy. We investigated the effect of dietary genistein (the...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.459
更新日期:2006-01-01 00:00:00
abstract::Schisandra chinensis (SC), a traditional herbal medicine, has been prescribed for patients suffering from various liver diseases, including hepatic cancer, hypercholesterolemia, and CCl₄-induced liver injury. We investigated whether SC extract has a protective effect on alcohol-induced fatty liver and studied its unde...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2013.2849
更新日期:2014-01-01 00:00:00
abstract::Telfairia occidentalis (Cucurbitaceae) is a leafy vegetable used in soup and folk medicine in southern Nigeria. Ethnobotanical survey revealed that preparations of the plant are used in the treatment of central nervous system-related disorders including convulsion. This study was conducted to investigate the effect of...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2012.0211
更新日期:2013-09-01 00:00:00
abstract::Enzymatic hydrolysates of Laminaria japonica were evaluated for antioxidative activities using hydroxyl radical scavenging activity and protective effects against H(2)O(2)-induced DNA and cell damage. In addition, activities of antioxidative enzymes, including catalase, glutathione peroxidase, and glutathione S-transf...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2007.0675
更新日期:2009-02-01 00:00:00
abstract::Standardized extracts of Echinacea, cat's claw, and saw palmetto were each evaluated for ability to activate macrophage and natural killer cells, in vitro, using two independent measures of activation for each immune cell population. A standard series of exposure concentrations were tested for each herbal extract in a...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.233
更新日期:2007-03-01 00:00:00
abstract::The intake of milk has decreased over the past few decades in Western populations and has been replaced by drinks of plant origin. Substitution of cow's milk by vegetable drinks occurs for some reasons, such as the presence of lactose intolerance, reduced calorie intake, prevention of obesity, vegan diets, and concern...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2020.0031
更新日期:2020-06-16 00:00:00
abstract::This is the first report about the modifying antibiotic activity of Eugenia uniflora L. and Eugenia jambolanum L. In this study the ethanol extract of E. uniflora and E. jambolanum was tested for their antimicrobial activity against strains of Escherichia coli. The growth of the two strains of E. coli bacteria tested ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2009.0158
更新日期:2010-08-01 00:00:00
abstract::The Korean Health/Functional Food Act of 2002 has led to the promotion of research on health/functional foods (HFFs). In order to track government-funded studies on HFFs, a free accessible database (National Research & Development on Functional Food, NaReaD(ff)) has been established by the Korea Food and Drug Administ...
journal_title:Journal of medicinal food
pub_type: 杂志文章,评审
doi:10.1089/jmf.2009.1036
更新日期:2009-12-01 00:00:00
abstract::The aim of this secondary analysis of a randomized controlled trial was to test whether the I148M variant of Patatin-like phospholipase domain-containing protein-3 (PNPLA3) is associated with the response to docosahexaenoic acid (DHA) in children with non-alcoholic fatty liver disease (NAFLD). Sixty children with NAFL...
journal_title:Journal of medicinal food
pub_type: 杂志文章,随机对照试验
doi:10.1089/jmf.2013.0043
更新日期:2013-10-01 00:00:00
abstract::To evaluate the effect of berberine (BBR) plus bezafibrate administration on the lipid profile of patients with mixed dyslipidemia. A double-blind randomized pilot clinical trial with parallel groups was carried out in 36 patients, aged 30-60 years with mixed dyslipidemia [triglycerides (TG) ≥1.7 mM and total choleste...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2020.0029
更新日期:2020-05-12 00:00:00
abstract::Sweet dream oral liquid (SDOL), a traditional Chinese herbal compound contains 17 traditional Chinese medicines. It has various pharmacological effects, such as improving brain dysfunction and increasing sleeping quality. This study investigated the neuroprotective effect and the underlying mechanisms of SDOL-impaired...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2015.3530
更新日期:2016-05-01 00:00:00
abstract::The aim of this study is to examine the in vitro antioxidant and antimicrobial activities of the acetone, methanol, and aqueous extracts of the lichens Cladonia furcata (many-forked Cladonia), Hypogymnia physodes (puffed lichen), and Umbilicaria polyphylla (manyleaf navel lichen) and the antimicrobial activity of fuma...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.0316
更新日期:2011-12-01 00:00:00
abstract::It remains unclear whether dietary supplementation with coenzyme Q10 (CoQ10) provides beneficial effects for healthy individuals, especially young subjects. This study investigated the effects of dietary supplementation with CoQ10 on oxidative stress in healthy young females. We performed a placebo-controlled trial us...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2014.3302
更新日期:2015-08-01 00:00:00
abstract::In the traditional system of medicine, the roots and rhizomes of Glycyrrhiza glabra have been employed clinically for centuries for their anti-inflammatory, anti-ulcer, expectorant, antimicrobial, and anxiolytic activities. The present study was undertaken to investigate the effects of G. glabra, popularly known as li...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2004.7.462
更新日期:2004-01-01 00:00:00
abstract::In Mexico about 4,000 plant species have some medicinal use. The aim of this work was to evaluate the antimicrobial activity of six Mexican medicinal plants against fungi and Gram-positive and Gram-negative bacteria. Methanolic extracts were prepared from the Mexican medicinal plants Amphypteringium adstrigens, Castel...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0205
更新日期:2009-12-01 00:00:00
abstract::We investigated the effect of solid-state fermented rice cultured with Basidiomycota (sangwhang) and Monascus ruber on lipid metabolism and antioxidant activity. Forty 4-week-old male Sprague-Dawley rats were fed high cholesterol diets in which carbohydrate sources in the treatment groups consisted of non-fermented ri...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.227
更新日期:2007-12-01 00:00:00
abstract::Fifty-four potential probiotic candidates were assayed for their phenotypic susceptibility to two batches of antibiotics manufactured by the same company, using the agar disc diffusion method on de Man, Rogosa, and Sharpe (MRS) agar. Cloxacillin was generally resisted (40.0-100%), while gentamicin (3.85-20.0%) was the...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0011
更新日期:2008-12-01 00:00:00
abstract::Supplements containing pharmacological concentrations of biotin are commercially available over the counter. Classical toxicity studies have considered biotin administration as harmless; however, recent investigations have shown that biotin supplementation modifies tissue morphology without changes in toxicity markers...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.0137
更新日期:2020-05-01 00:00:00
abstract::Ingestion of bioactive compounds, such as hesperidin and naringin, found in citrus fruits and orange juice, can improve the homeostasis of gut microbiota. A controlled clinical study with temporal series intergroup design with 10 apparently healthy women (28.5 ± 8.4 years, 24.1 ± 3.3 kg/m2) were evaluated after contin...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2018.0080
更新日期:2019-02-01 00:00:00
abstract::Temporal lobe epilepsy (TLE) is the most common form of localization-related epilepsy, with the highest prevalence rate in adulthood. Recently, we reported the beneficial effects of the individual treatment with flavonoids such as silibinin and morin in kainic acid (KA)-treated mouse model for TLE. In this study, we i...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.4522
更新日期:2020-02-01 00:00:00
abstract::Diabetes is a chronic degenerative disease with no cure, is found in millions of people worldwide, and can cause life-threatening complications at any age. The plant Cissus sicyoides L. is a runner plant found abundantly in Brazil, especially in the Amazon. Its therapeutic properties are widely used in popular medicin...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0157
更新日期:2009-08-01 00:00:00
abstract::The effect of supplementation of a powdered mixture of three traditional medicinal plants-bittergourd, jamun seeds, and fenugreek seeds-in raw and cooked form on blood glucose was studied in 60 non-insulin-dependent male diabetics. The patients were divided into two groups of 30 each. The patients of group I were give...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2005.8.545
更新日期:2005-01-01 00:00:00
abstract::The biological activities of garlic may be affected by different processing methods. This study, therefore, aimed to evaluate potential anticancer effects of different type of processed garlic extracts on WEHI-164 tumor cells in inbred BALB/c mice and correlate the tumor growth rates with some garlic constituents. In ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.1594
更新日期:2011-09-01 00:00:00
abstract::This study was designed to evaluate the effect of dietary conjugated linoleic acid (CLA) on endurance exercise and availability of metabolic substrates in mice. Four-week-old male BALB/c mice were randomized to a control group (normal diet) and a CLA group (normal diet + 1% CLA). Each animal group received its respect...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2009.1358
更新日期:2010-10-01 00:00:00
abstract::Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of diabetes mellitus. Although phenolic compounds attenuate oxidative stress-related damage, there are concerns over toxicity of synthetic phenolic antioxidants, and this has considerably...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2005.8.251
更新日期:2005-07-01 00:00:00
abstract::Vineatrol®30 (developed and produced jointly by Breko GmbH [Bremen, Germany] and Actichem [Montauban, France]) is a grapevine-shoot extract that contains resveratrol as well as considerable amounts of resveratrol oligomers. In the present study it is shown that Vineatrol30 at a noncytotoxic concentration of 2.3 μg/mL ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.0022
更新日期:2011-01-01 00:00:00
abstract::Several biological and clinical studies have suggested that conjugated linoleic acid (CLA) prevents body fat accumulation and increases lean body mass. CLA is available as a concentrated dietary supplement and is purported to provide the aforementioned benefits for people who perform physical activity. This study was ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.0144
更新日期:2012-04-01 00:00:00