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New adjuvants to enhance anticoagulant activity of warfarin.

Abstract：

:New adjuvants of warfarin anticoagulant activity have been developed. These compounds, which are 1,4-methano-1,2,3,4-tetrahydroanthracene-9,10-diol derivatives, act synergistically with warfarin to potentiate its anticoagulant effect. None of the compounds tested is an effective oral anticoagulant in the absence of warfarin.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Stromich JJ,Weber AK,Mirzaei YR,Caldwell MD,Lewis DE

doi

10.1016/j.bmcl.2010.01.123

subject

Has Abstract

pub_date

2010-03-15 00:00:00

pages

1928-32

issue

6

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(10)00135-6

journal_volume

20

pub_type

杂志文章

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