Fat mass threshold associated with a significant deterioration of insulin sensitivity in postmenopausal women.

Abstract:

:The aim of this study was to establish a cut-off value of percentage of fat mass (%FM) at which insulin sensitivity (IS) is significantly altered in sedentary postmenopausal women. Our results suggest that maintaining a %FM below 41% would minimize the deterioration of IS and its associated risks.

authors

Bobeuf F,Aubertin-Leheudre M,Lord C,Labonté M,Khalil A,Dionne IJ

doi

10.1016/j.diabres.2010.01.010

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

e1-3

issue

1

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(10)00012-4

journal_volume

88

pub_type

杂志文章
  • Glycemic control and its correlates in patients with diabetes in Venezuela: results from a nationwide survey.

    abstract:AIMS:To determine the prevalence of inadequate glycemic control and its correlates in a large multicenter survey of Venezuelan patients with diabetes. METHODS:A cross-sectional study in a sample of adult patients with diabetes, attending health centers in Venezuela. Information about diabetes, current medications, com...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2009.12.014

    authors: Moreira ED Jr,Neves RC,Nunes ZO,de Almeida MC,Mendes AB,Fittipaldi JA,Ablan F,Venezuelan Diabetes Investigators' Group.

    更新日期:2010-03-01 00:00:00

  • Effect of corosolic acid on postchallenge plasma glucose levels.

    abstract::Corosolic acid (CRA) is a substance extracted from Lagerstroemia speciosa L. and has been reported to have biological activities in in vitro and experimental animal studies. In this study, 31 subjects were orally administered 10mg CRA or a placebo, on different occasions, in a capsule 5min before the 75-g oral glucose...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2006.01.010

    authors: Fukushima M,Matsuyama F,Ueda N,Egawa K,Takemoto J,Kajimoto Y,Yonaha N,Miura T,Kaneko T,Nishi Y,Mitsui R,Fujita Y,Yamada Y,Seino Y

    更新日期:2006-08-01 00:00:00

  • Social network and development of prediabetes and type 2 diabetes in middle-aged Swedish women and men.

    abstract:AIM:Explore if social network affects development of prediabetes and type 2 diabetes. METHODS:Individuals with normal glucose tolerance at baseline, 2924 women and 2039 men, aged 35-56 years, were followed-up 8-10 years later by an oral glucose tolerance test. Prediabetes and type 2 diabetes was then evident in 168 an...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2014.09.057

    authors: Hilding A,Shen C,Östenson CG

    更新日期:2015-01-01 00:00:00

  • Pericytes and the prevention of diabetic retinopathy.

    abstract::Diabetic retinopathy is a leading cause of blindness and one of the hallmarks of early diabetic retinopathy is death of pericytes. I studied the effect of glycated albumin (GA) on the retinal pericyte death and assessed the protective effects of some well-known antioxidant materials. GA produced a progressive cytotoxi...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2003.10.027

    authors: Kim J

    更新日期:2004-12-01 00:00:00

  • Time-course changes in clinical features of early-onset Japanese type 1 and type 2 diabetes: TWMU hospital-based study.

    abstract::Using a database of patients with type 1 (n=1675) and type 2 (n=2259) diabetes diagnosed before the age of 30 years at the Diabetes Center, Tokyo Women's Medical University (TWMU), in which such Japanese patients have been registered at the time of first visit since the 1960s, we performed a hospital-based study over ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.06.021

    authors: Uchigata Y,Otani T,Takaike H,Miura J,Osawa M,Tukahara S,Kasahara T,Iwamoto Y

    更新日期:2008-10-01 00:00:00

  • Out-patient management does not impair outcome of pregnancy in women with type 1 diabetes.

    abstract::In recent years, out-patient protocols have mainly displaced historical obstetric management of diabetic pregnancy. The impact of the change from centralized in-patient to decentralized out-patient treatment on glycaemic control and its effects on the outcome of newborns in diabetic pregnancies was therefore studied u...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(99)00120-5

    authors: Vääräsmäki M,Hartikainen AL,Anttila M,Pirttiaho H

    更新日期:2000-02-01 00:00:00

  • Vaspin and its correlation with insulin sensitivity indices in obese children.

    abstract:AIM:The aim of this study was to assess the vaspin and adiponectin concentrations on markers of insulin sensitivity and obesity in pubertal obese children and adolescents. MATERIAL AND METHODS:Plasma vaspin and adiponectin level and its relationships with body mass index standard deviation score (BMI-SDS), insulin sen...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.03.008

    authors: Suleymanoglu S,Tascilar E,Pirgon O,Tapan S,Meral C,Abaci A

    更新日期:2009-06-01 00:00:00

  • A case of fulminant type 1 diabetes mellitus with exocrine pancreatic insufficiency and enhanced glucagon response to meal ingestion.

    abstract::Non-specific aggression to endocrine alpha and beta cells as well as exocrine pancreas has been suggested in fulminant type 1 diabetes (FT1DM), while its effect on glucagon secretion and exocrine function is unknown. Here, we report a FT1DM case with exocrine pancreatic insufficiency and enhanced glucagon response to ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.08.004

    authors: Yabe D,Kuroe A,Ohya M,Watanabe K,Kitatani N,Oku M,Kurose T,Seino Y

    更新日期:2008-11-01 00:00:00

  • Combined effect of exogenous insulin and sucrose on alterations in plasma lipoproteins induced by cholesterol feeding in the rat.

    abstract::We have recently reported increased cholesterol concentrations in high-density and very-low-density lipoproteins (HDL and VLDL) in sucrose-fed rats with exogenous hyperinsulinemia. In order to see if exogenous hyperinsulinemia has any effect on the alterations in plasma lipoproteins induced by cholesterol feeding, we ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(89)90032-6

    authors: Kazumi T,Yoshino G,Kasama T,Iwatani I,Tanaka T,Baba S

    更新日期:1989-04-01 00:00:00

  • Clinical experience with BIAsp 30: results from the Indonesian cohort of the international A₁chieve study.

    abstract:AIM:To evaluate the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in Indonesian patients with type 2 diabetes (T2D) as part of the 24-week, international, prospective, non-interventional A₁chieve study. METHODS:Indonesian patients who started BIAsp 30 were included. Safety and efficacy was measured...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/S0168-8227(13)70011-1

    authors: Soewondo P,Pramono RB,Langi YA,Soetedjo NN,Kshanti IA

    更新日期:2013-04-01 00:00:00

  • Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.

    abstract:AIMS:Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.06.021

    authors: Tavridou A,Petridis I,Vasileiadis M,Ragia G,Heliopoulos I,Vargemezis V,Manolopoulos VG

    更新日期:2011-11-01 00:00:00

  • Achievement of metabolic control goals set by the American Diabetes Association and the International Society for Pediatric and Adolescent Diabetes in pediatric patients with type 1 diabetes from Spain.

    abstract:AIM:The "T1D Exchange Clinic Registry" of 13.316 pediatric patients with type 1 diabetes (T1D) in U.S. recently revealed that most children have HbA1c values above target levels established by the American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD). The aim of...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2014.08.033

    authors: Enes P,Martín-Frías M,Álvarez MÁ,Yelmo R,Alonso M,Barrio R

    更新日期:2015-02-01 00:00:00

  • Clinical predictors differentiating non-diabetic renal diseases from diabetic nephropathy in a large population of type 2 diabetes patients.

    abstract:AIMS:Non-diabetic renal diseases (NDRDs) are associated with better renal outcomes than diabetic nephropathy (DN). This study was conducted to determine the common clinical markers predicting NDRDs in type 2 diabetes patients. METHODS:Patients with type 2 diabetes mellitus who underwent a renal biopsy were screened. E...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.09.005

    authors: Dong Z,Wang Y,Qiu Q,Zhang X,Zhang L,Wu J,Wei R,Zhu H,Cai G,Sun X,Chen X

    更新日期:2016-11-01 00:00:00

  • Association of sulfonylurea receptor 1 genotype with therapeutic response to gliclazide in type 2 diabetes.

    abstract::To investigate the effects of sulfonylurea receptor 1 (SUR1) exon 33 (TCC-->GCC, S1369A) polymorphism on responsiveness to gliclazide. About 115 patients with type 2 diabetes were treated with gliclazide for 8 weeks. SUR1 genotypes were tested by Taqman-PCR. After gliclazide treatment, there was association between T/...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2006.10.021

    authors: Zhang H,Liu X,Kuang H,Yi R,Xing H

    更新日期:2007-07-01 00:00:00

  • The effectiveness and safety of beginning insulin aspart together with basal insulin in people with type 2 diabetes in non-Western nations: results from the A₁chieve observational study.

    abstract:AIMS:The aim of this A₁chieve sub-group analysis was to examine populations beginning insulin aspart together with any basal insulin, all ± oral glucose lowering drugs: insulin aspart added to existing basal insulin (n=519); switched from biphasic insulin (n=947); switched from NPH plus human meal-time insulins (n=586)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2013.06.005

    authors: Home PD,Latif ZA,González-Gálvez G,Prusty V,Hussein Z

    更新日期:2013-09-01 00:00:00

  • On what evidence-base do we recommend self-monitoring of blood glucose?

    abstract::Self-monitoring of blood glucose (SMBG) has been considered one major breakthrough in diabetes therapy because, for the first time, patients were able to determine their blood glucose levels during daily life. It seems obvious that this must be of advantage to disease management and clinical outcome, but it has become...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2009.10.014

    authors: Kolb H,Kempf K,Martin S,Stumvoll M,Landgraf R

    更新日期:2010-02-01 00:00:00

  • Serum level of the autophagy biomarker Beclin-1 in patients with diabetic kidney disease.

    abstract::Autophagy is a major cellular clearance mechanism that maintains cellular survival and homeostasis. Autophagy has a crucial role in the progression of diabetes and kidney diseases. AIMS:To investigate serum concentrations of Beclin-1, a key regulator of autophagy, in patients with diabetic kidney disease (DKD). METH...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.06.022

    authors: Naguib M,Rashed LA

    更新日期:2018-09-01 00:00:00

  • Pioglitazone enhances splanchnic glucose uptake as well as peripheral glucose uptake in non-insulin-dependent diabetes mellitus. AD-4833 Clamp-OGL Study Group.

    abstract::To evaluate the effect of pioglitazone on insulin resistance in non-insulin-dependent diabetes mellitus (NIDDM) patients, a double-blind placebo-controlled trial was carried out with 30 NIDDM patients. Twenty-one subjects, three on diet alone and 18 on sulfonylurea (SU), orally received 30 mg pioglitazone once daily f...

    journal_title:Diabetes research and clinical practice

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0168-8227(98)00056-4

    authors: Kawamori R,Matsuhisa M,Kinoshita J,Mochizuki K,Niwa M,Arisaka T,Ikeda M,Kubota M,Wada M,Kanda T,Ikebuchi M,Tohdo R,Yamasaki Y

    更新日期:1998-07-01 00:00:00

  • Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity.

    abstract:AIMS:The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. METHODS:In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed criticall...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2020.108331

    authors: Halvatsiotis P,Kotanidou A,Tzannis K,Jahaj E,Magira E,Theodorakopoulou M,Konstandopoulou G,Gkeka E,Pourzitaki C,Kapravelos N,Papoti S,Sileli M,Gogos C,Velissaris D,Markou N,Stefanatou E,Vlachogianni G,Aimoniotou E,Kom

    更新日期:2020-08-01 00:00:00

  • Prognostic nomogram and score to predict renal survival of patients with biopsy-proven diabetic nephropathy.

    abstract:AIMS:Both clinical and pathogenetic markers for accurate prediction of end-stage renal disease in diabetic nephropathy (DN) are lacking. This study aimed to establish an effective prognostic nomogram and a score for renal survival (RS) in biopsy-proven DN. METHODS:Analyses were derived from 110 DN patients who underwe...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.107809

    authors: Jiang S,Yu T,Zhang Z,Fang J,Wang Y,Yang Y,Liu L,Zou G,Gao H,Zhuo L,Li W

    更新日期:2019-09-01 00:00:00

  • Ten-year incidence of diabetic retinopathy and macular edema. Risk factors in a sample of people with type 1 diabetes.

    abstract:AIMS:To determine the 10-year incidence of diabetic retinopathy (DR) and macular edema (DME), and its relationship with its risk factors in a sample of type 1 diabetes mellitus. METHODS:A total of 334 patients without diabetic retinopathy at baseline underwent a 10-year prospective study, the risk factors included: ag...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.07.004

    authors: Romero-Aroca P,Baget-Bernaldiz M,Fernandez-Ballart J,Plana-Gil N,Soler-Lluis N,Mendez-Marin I,Bautista-Perez A

    更新日期:2011-10-01 00:00:00

  • Increased peripheral blood mitochondrial DNA in type 2 diabetic patients with nephropathy.

    abstract::We report that mitochondrial DNA (MtDNA) copy numbers are increased in peripheral blood of patients with diabetic nephropathy (DN). Using qPCR for quantitation, we found a 2-4-fold significant increase (p<0.05) in the mean MtDNA values in DN patients vs. healthy controls and diabetics without nephropathy. Increased Mt...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.07.002

    authors: Malik AN,Shahni R,Iqbal MM

    更新日期:2009-11-01 00:00:00

  • Stroke in the patient with diabetes (Part 2) - Prevention and the effects of glucose lowering therapies.

    abstract::There is a higher incidence of stroke in both the type 2 diabetic and the non-diabetic insulin resistant patient which is accompanied by higher morbidity and mortality. Stroke primary prevention can be achieved by controlling atrial fibrillation and hypertension, and the utilization of statins and anticoagulant therap...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2020.108199

    authors: Bell DSH,Goncalves E

    更新日期:2020-06-01 00:00:00

  • Impaired fasting plasma glucose is a risk indicator of interventricular septum thickening among non-diabetic subjects with obesity.

    abstract:AIMS:To evaluate whether progressively higher fasting plasma glucose (FPG) is associated to thickening of the interventricular septum (IVS) among non-diabetic subjects with obesity. METHODOLOGY:We studied 227 consecutive non diabetic patients (155 women and 72 men, age range 18-72 years) with overweight or obesity (BM...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108436

    authors: Zupo R,Castellana F,Sardone R,Scicchitano P,Lampignano L,Ciccone MM,Triggiani V,Guastamacchia E,Giannelli G,De Pergola G

    更新日期:2020-11-01 00:00:00

  • Ramadan fasting and diabetes 2019: The year in review.

    abstract:INTRODUCTION:The literature on health aspects of Ramadan fasting is widely spread in many journals making it not readily available to those interested in the subject. MATERIALS AND METHODS:A narrative, non-systematic review of the international literature from two major online databases (viz. Scopus, PubMed) in one ye...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2020.108593

    authors: Beshyah SA,Ali KF,Hafidh K,Hajjaji IM

    更新日期:2020-12-11 00:00:00

  • Glucolipotoxicity and beta cells in type 2 diabetes mellitus: target for durable therapy?

    abstract::Type 2 diabetes mellitus (T2DM) is characterised by beta-cell failure in the setting of obesity-related insulin resistance. Progressive beta-cell dysfunction determines the course of the disease, regardless of the treatment used. There is mounting evidence that chronically elevated circulating levels of glucose and fa...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/S0168-8227(11)70012-2

    authors: van Raalte DH,Diamant M

    更新日期:2011-08-01 00:00:00

  • Risk factors associated with the progression of COVID-19 in elderly diabetes patients.

    abstract:AIM:To describe the clinical characteristics and risk factors associated with the progression of COVID-19 in elderly diabetes patients. METHODS:This was a retrospective cohort study, including elderly COVID-19 patients admitted to Wuhan Huoshenshan Hospital between February 10 and 13, 2020. Demographic data, medical h...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108550

    authors: Zhang P,Wang M,Wang Y,Wang Y,Li T,Zeng J,Wang L,Li C,Gong Y

    更新日期:2020-11-21 00:00:00

  • Predictors of mortality from type 2 diabetes mellitus in Canterbury, New Zealand; a ten-year cohort study.

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    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(01)00246-7

    authors: Florkowski CM,Scott RS,Coope PA,Moir CL

    更新日期:2001-08-01 00:00:00

  • Contraception in diabetic women: an Italian study.

    abstract:UNLABELLED:Over 1 year, a survey on contraception and obstetric history was performed on a cohort of 667 Caucasian fertile diabetic women (446, type 1 and 201, type 2) living in Italy. RESULTS:Of these women, 30.4% used hormonal contraceptives, 12.0% intra-uterine device (IUD), 10.7% declared they used no contraceptio...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.07.020

    authors: Napoli A,Colatrella A,Botta R,Di Cianni G,Fresa R,Gamba S,Italia S,Mannino D,Piva I,Suraci C,Tonutti L,Torlone E,Tortul C,Lapolla A,Italian Diabetic Pregnancy Study Group (SID).

    更新日期:2005-03-01 00:00:00

  • Non-insulin-dependent diabetes in Kuwait: prevalence rates and associated risk factors.

    abstract::Non-insulin-dependent diabetes mellitus (NIDDM) is a major clinical and public health problem in Kuwait. The objective of the study was to determine prevalence rates of NIDDM among a representative sample of the Kuwaiti adult population aged 20 and older in two out of five governorates and identify the associated risk...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(98)00104-1

    authors: Abdella N,Al Arouj M,Al Nakhi A,Al Assoussi A,Moussa M

    更新日期:1998-12-01 00:00:00