Abstract：
:MR connectomics is an emerging framework in neuro-science that combines diffusion MRI and whole brain tractography methodologies with the analytical tools of network science. In the present work we review the current methods enabling structural connectivity mapping with MRI and show how such data can be used to infer new information of both brain structure and function. We also list the technical challenges that should be addressed in the future to achieve high-resolution maps of structural connectivity. From the resulting tremendous amount of data that is going to be accumulated soon, we discuss what new challenges must be tackled in terms of methods for advanced network analysis and visualization, as well data organization and distribution. This new framework is well suited to investigate key questions on brain complexity and we try to foresee what fields will most benefit from these approaches.
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Hagmann P,Cammoun L,Gigandet X,Gerhard S,Grant PE,Wedeen V,Meuli R,Thiran JP,Honey CJ,Sporns Odoi
10.1016/j.jneumeth.2010.01.014subject
Has Abstractpub_date
2010-12-15 00:00:00pages
34-45issue
1eissn
0165-0270issn
1872-678Xpii
S0165-0270(10)00036-1journal_volume
194pub_type
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