When to treat a diabetic patient using an external insulin pump. Expert consensus. Société francophone du diabète (ex ALFEDIAM) 2009.

Abstract:

:For years, external insulin pumps have enjoyed proven efficacy as an intensive diabetes treatment to improve glycaemic control and reduce hypoglycaemia. Since the last ALFEDIAM guidelines in 1995, however, basal-bolus treatment using a combination of long- and short-acting insulin analogues have emerged and could challenge, at a lower cost, the efficacy of pumps using rapid-acting insulin analogues, considered the 'gold standard' of insulin treatment. Nevertheless, given its theoretical and practical advantages, some patients will derive more benefit from pump treatment. These cases have been carefully evaluated in the literature by a panel of experts appointed by ALFEDIAM to determine the indications for pump treatment. In patients with type 1 diabetes, persistent elevated HbA(1c) despite multiple daily injections (MDI), and repeated hypoglycaemia and high glycaemic variability, represent the most validated indications. In patients with type 2 diabetes, pump treatment may be indicated in cases of MDI failure to achieve HbA(1c) targets. Absolute contraindications are rare, and comprise severe psychiatric disorders, rapidly progressing ischaemic or proliferative retinopathy before laser treatment and exposure to high magnetic fields. Relative contraindications are mostly related to the patient's lack of compliance or inability to cope with the treatment, and need to be evaluated individually to clearly assess the benefit/risk ratio for the given patient. However, as these conditions are progressive, there should also be annual reassessment of the appropriateness of pump treatment. Specific education on pump treatment initially and throughout the follow-up, delivered by experienced medical and paramedical teams, are the best guarantees of treatment efficacy and safety.

journal_name

Diabetes Metab

journal_title

Diabetes & metabolism

authors

Lassmann-Vague V,Clavel S,Guerci B,Hanaire H,Leroy R,Loeuille GA,Mantovani I,Pinget M,Renard E,Tubiana-Rufi N,Société francophone du diabète (ex ALFEDIAM).

doi

10.1016/j.diabet.2009.09.002

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

79-85

issue

1

eissn

1262-3636

issn

1878-1780

pii

S1262-3636(09)00253-5

journal_volume

36

pub_type

杂志文章,实务指引
  • [Molecular mechanisms of insulin secretion].

    abstract::Insulin secretion from the beta-cells in the islets of Langerhans is mainly regulated by glucose entry via its transporter. The intracellular glucose metabolism induces a rise in ATP/ADP ratio which increases the degree of closure of ATP-sensitive potassium channels (K(ATP) channels), inducing a higher intracellular K...

    journal_title:Diabetes & metabolism

    pub_type: 评论,杂志文章,评审

    doi:

    authors: Bataille D

    更新日期:2002-12-01 00:00:00

  • The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial: the Inter99 study.

    abstract:AIM:This study aimed to assess whether group-based lifestyle counselling offered to a high-risk population subgroup had any effect beyond individual multifactorial interventions on fasting plasma glucose (FPG) and 2-h plasma glucose (2hPG) changes. METHODS:In a population-based study of 6784 participants, 4053 were de...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabet.2011.06.001

    authors: Lau C,Vistisen D,Toft U,Tetens I,Glümer C,Pedersen O,Jørgensen T,Borch-Johnsen K

    更新日期:2011-12-01 00:00:00

  • Significant Association between Blood Lead (Pb) Level and Haemoglobin A1c in Non-diabetic Population.

    abstract::Although many heavy metals are necessary for normal biological function, a subset of heavy metals have no role in human physiology, such as lead (Pb) and arsenic (As). Such elements have deleterious effects on physiology and be associated with the incidence of diabetes and related metabolic syndromes. Haemoglobin A1c ...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2021.101233

    authors: Chang CW,Wang CW,Wu DW,Lee WH,Chen YC,Liu YH,Li CH,Tsai CC,Lin WY,Chen SC,Hung CH,Kuo CH,Su HM

    更新日期:2021-01-23 00:00:00

  • IL-33 receptor ST2 deficiency attenuates renal ischaemia-reperfusion injury in euglycaemic, but not streptozotocin-induced hyperglycaemic mice.

    abstract:AIM:Kidney hypoxia can predispose to the development of acute and chronic renal failure in diabetes. Ischaemia-reperfusion injury (IRI) causes inflammation, and diabetes is known to exacerbate this inflammatory response in the kidney, whereas alarmin IL-33 could act as an innate immune mediator during kidney IRI. Thus,...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2017.06.008

    authors: Sehnine M,Ferhat M,Sena S,Gombert JM,Goujon JM,Thierry A,Touchard G,Hauet T,Herbelin A,Hadjadj S

    更新日期:2018-02-01 00:00:00

  • Vitamin D deficiency, vitamin D receptor gene polymorphisms and cardiovascular risk factors in Caribbean patients with type 2 diabetes.

    abstract:AIM:The prevalence of diabetes in the French West Indies is three times higher than in mainland France. We aimed to assess the associations between vitamin D deficiency, vitamin D receptor (VDR) gene polymorphisms and cardiovascular risk factors in Caribbean patients with type 2 diabetes (T2D). METHODS:In this cross-s...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2011.05.005

    authors: Vélayoudom-Céphise FL,Larifla L,Donnet JP,Maimaitiming S,Deloumeaux J,Blanchet A,Massart C,Munoz-Bellili N,Merle S,Chout R,Bonnet F,Foucan L

    更新日期:2011-12-01 00:00:00

  • Screening of cardiovascular autonomic neuropathy in patients with diabetes using non-invasive quick and simple assessment of sudomotor function.

    abstract:AIM:Cardiovascular autonomic neuropathy (CAN) is a common but often overlooked complication of diabetes. Sympathetic C-fibers innervating sweat glands can be impaired early on in patients with diabetes. In this study, SUDOSCAN, a new non-invasive device that assesses sudomotor function was compared to methods generally...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2012.09.004

    authors: Yajnik CS,Kantikar V,Pande A,Deslypere JP,Dupin J,Calvet JH,Bauduceau B

    更新日期:2013-04-01 00:00:00

  • Relation of C-reactive protein to features of the metabolic syndrome in normal glucose tolerant, impaired glucose tolerant, and newly diagnosed type 2 diabetic subjects.

    abstract:OBJECTIVE:To determine the relationship between CRP levels and the components of MS in normal glucose tolerant (NGT), impaired glucose tolerant (IGT), and Type 2 diabetic subjects. MATERIAL AND METHODS:A based cross-sectional population study was performed. Eligible subjects, men and non-pregnant women, 30 to 64 year ...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/s1262-3636(07)70009-5

    authors: Guerrero-Romero F,Rodríguez-Morán M

    更新日期:2003-02-01 00:00:00

  • Plasma levels of tumor necrosis factor-alpha (TNF-alpha) are essentially dependent on visceral fat amount in type 2 diabetic patients.

    abstract::TNF-alpha is considered as one of the potential determinants of insulin resistance. However several data suggest that TNF-alpha expression itself, could be modulated by the degree of adiposity and/or plasma insulin levels. To clarify the determinants of plasma TNF-alpha levels in type 2 diabetes mellitus, we studied t...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:

    authors: Bertin E,Nguyen P,Guenounou M,Durlach V,Potron G,Leutenegger M

    更新日期:2000-05-01 00:00:00

  • WISE recommendations to ensure the safety of injections in diabetes.

    abstract:AIM:Injections and fingersticks administered to patients with diabetes in health care settings present a risk of blood exposure to the injector as well as other workers in potential contact with sharps. Such exposures could lead to transmission of bloodborne pathogens such as hepatitis and HIV. A recent EU Directive re...

    journal_title:Diabetes & metabolism

    pub_type: 共识发展会议,杂志文章,实务指引,评审

    doi:10.1016/S1262-3636(12)70975-8

    authors: Strauss K,WISE Consensus Group.

    更新日期:2012-01-01 00:00:00

  • Type 2 diabetes treatment intensification in general practice in France in 2008-2009: the DIAttitude Study.

    abstract:AIMS:To evaluate the current procedures in French general practice of intensifying hypoglycaemic treatment in orally treated type 2 diabetic patients, according to the French recommendations. METHODS:Type 2 diabetic patient characteristics, HbA(1c) values, hypoglycaemic treatment and physician characteristics were col...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/S1262-3636(12)71532-X

    authors: Balkau B,Bouée S,Avignon A,Vergès B,Chartier I,Amelineau E,Halimi S

    更新日期:2012-03-01 00:00:00

  • [Macronutrients, fat mass, fatty acid flux and insulin sensitivity].

    abstract::Obesity and visceral or upper body fat distribution, have a major impact on insulin sensitivity. There is strong evidence to suggest that free fatty acids (FFA) contribute to the pathogenesis of insulin resistance and the metabolic syndrome. Increased FFA release from adipose tissue or failure of FFA using tissues to ...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:

    authors: Ziegler O,Quilliot D,Guerci B,Drouin P

    更新日期:2001-04-01 00:00:00

  • Racial differences in the association between body fat distribution and lipid profiles among reproductive-age women.

    abstract:AIM:The aim of this study was to examine the racial and ethnic differences in the relationship between body fat distribution variables and serum lipid profiles. METHODS:Secondary data analyses were conducted on 708 healthy women (204 blacks, 247 whites and 257 Hispanics), aged 16-33 years, seen in an outpatients clini...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2010.01.010

    authors: Hosain GM,Rahman M,Williams KJ,Berenson AB

    更新日期:2010-09-01 00:00:00

  • Propranolol in hypoglycaemia unawareness.

    abstract::The effect of propranolol on the occurrence of hypoglycaemic symptoms was assessed in insulin-dependent diabetic patients with hypoglycaemia unawareness. A double-blind, randomised parallel group study (2:1 fashion) was conducted over 4-week period. The propranolol group (n = 9) received 20 mg (week 1 and 2) and 30 mg...

    journal_title:Diabetes & metabolism

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Chalon S,Berlin I,Sachon C,Bosquet F,Grimaldi A

    更新日期:1999-03-01 00:00:00

  • Hypoglycaemic episodes in patients with type 2 diabetes--risk factors and associations with patient-reported outcomes: The PANORAMA Study.

    abstract:AIM:To explore the frequency of hypoglycaemic episodes, their risk factors, and associations with patient-reported outcomes in patients with type 2 diabetes enrolled in the PANORAMA cross-sectional study. METHODS:Five thousand seven hundred and eighty-three patients aged ≥ 40 years with type 2 diabetes duration ≥ 1 ye...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2015.08.007

    authors: Simon D,de Pablos-Velasco P,Parhofer KG,Gönder-Frederick L,Duprat Lomon I,Vandenberghe H,Eschwège E,Bradley C

    更新日期:2015-12-01 00:00:00

  • Adverse metabolic disorders during highly active antiretroviral treatments (HAART) of HIV disease.

    abstract::Protease inhibitor treatment has dramatically improved rates of morbidity and mortality in HIV-infected patients. However, it has recently been shown that this medication is associated with long-term side effects characterized by metabolic, clinical and biological alterations. These modifications have been described i...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:

    authors: Vigouroux C,Gharakhanian S,Salhi Y,Nguyên TH,Adda N,Rozenbaum W,Capeau J

    更新日期:1999-11-01 00:00:00

  • The incidence and persistence of the NCEP (National Cholesterol Education Program) metabolic syndrome. The French D.E.S.I.R. study.

    abstract:CONTEXT:In 2001 the "National Cholesterol and Education Program Expert Panel" gave a clinical definition of the metabolic syndrome. The frequency of this syndrome at baseline and its incidence and persistence at three years is studied in a French population. SUBJECTS:2109 men and 2184 women from the D.E.S.I.R. longitu...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/s1262-3636(07)70067-8

    authors: Balkau B,Vernay M,Mhamdi L,Novak M,Arondel D,Vol S,Tichet J,Eschwège E,D.E.S.I.R. Study Group.

    更新日期:2003-11-01 00:00:00

  • Trends from 1995 to 2006 in the prevalence of self-reported cardiovascular risk factors among elderly Spanish diabetics.

    abstract:AIM:In this study, we examined the trends from 1995 to 2006 in cardiovascular risk factors (CVRF) in Spaniards aged 65 years or older with diabetes. METHODS:We looked at the individual data from adults aged > or =65 years from the Spanish National Health Surveys of 1995 (n=1117), 1997 (n=1111), 2001 (n=4328), 2003 (n=...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2009.06.007

    authors: Jiménez Trujillo I,Jiménez García R,Vazquez-Fernandez del Pozo S,Hernández Barrera V,Carrasco Garrido P,Suarez P,Gil de Miguel A

    更新日期:2010-02-01 00:00:00

  • Serum levels of osteopontin predict diabetes remission after bariatric surgery.

    abstract:AIM:Bariatric surgery has been shown to effectively improve glycaemic control in morbidly obese subjects. However, the molecular bases of this association are still elusive and may act independently of weight loss. Here, our retrospective study has investigated the inflammatory molecule osteopontin (OPN) as a potential...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2018.09.007

    authors: Carbone F,Adami G,Liberale L,Bonaventura A,Bertolotto M,Andraghetti G,Scopinaro N,Camerini GB,Papadia FS,Cordera R,Dallegri F,Montecucco F

    更新日期:2019-09-01 00:00:00

  • Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study.

    abstract:AIMS:Reactive dicarbonyl compounds, such as methylglyoxal (MGO), rise during an oral glucose tolerance test (OGTT), particularly in (pre)diabetes. Fasting MGO levels are associated with chronic kidney disease (CKD) and cardiovascular disease (CVD) in patients with poorly controlled type 2 diabetes mellitus (T2DM). Yet,...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2020.02.002

    authors: Hanssen NMJ,Scheijen JLJM,Houben AJHM,van de Waarenburg M,Berendschot TTJM,Webers CAB,Reesink KD,van Greevenbroek MMJ,van der Kallen C,Schaper NC,Schram MT,Henry RMA,Stehouwer CDA,Schalkwijk CG

    更新日期:2020-02-10 00:00:00

  • How can we measure insulin sensitivity/resistance?

    abstract::Insulin resistance represents a major public health problem, as it plays a major role in the pathophysiology of type 2 diabetes mellitus; it is also associated with increased cardiovascular risk and atherogenic dyslipidaemia, and is a central component of the cluster of metabolic abnormalities that comprise the metabo...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabet.2011.01.002

    authors: Antuna-Puente B,Disse E,Rabasa-Lhoret R,Laville M,Capeau J,Bastard JP

    更新日期:2011-06-01 00:00:00

  • Methods for the screening and diagnosis of gestational diabetes mellitus between 24 and 28 weeks of pregnancy.

    abstract::The aim of this review is to provide answers to the question “How does one screen for and diagnose gestational diabetes mellitus (GDM) between 24 and 28 weeks gestation?” Two methods are currently widely used: a one-step approach (the 75g-Oral Glucose Tolerance Test, OGTT) and a two-step approach (the 50g Glucose Chal...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabet.2010.11.008

    authors: Virally M,Laloi-Michelin M

    更新日期:2010-12-01 00:00:00

  • Disability and quality of life in elderly people with diabetes.

    abstract::To implement preventive policies of disability in older diabetic people, the role of diabetes in the disablement process should be investigated. Diabetes mellitus is consistently associated with a higher prevalence of disability at all states, as well as with a progression in disability states and may be considered as...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:10.1016/s1262-3636(07)80058-9

    authors: Bourdel-Marchasson I,Helmer C,Fagot-Campagna A,Dehail P,Joseph PA

    更新日期:2007-04-01 00:00:00

  • Factors related to CSII compliance.

    abstract::Many studies have demonstrated the metabolic efficacy of continuous subcutaneous insulin infusion (CSII) and particularly a reduction of glycaemic fluctuations in type 1 diabetic patients. Despite this benefit, many patients decide to discontinue the use of CSII. To determine the factors related to discontinuation of ...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/s1262-3636(07)70173-8

    authors: Ronsin O,Jannot-Lamotte MF,Vague P,Lassman-Vague V

    更新日期:2005-02-01 00:00:00

  • NOD1 activation induces innate immune responses and insulin resistance in human adipocytes.

    abstract:AIMS:The innate immune-receptor nucleotide oligomerization domain (NOD) protein recognizes intracellular bacterial peptidoglycan. Activation of the innate immune system contributes to the development and progression of insulin resistance. The present study aimed to determine the presence of NOD1 and NOD2 in human adipo...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2012.08.001

    authors: Zhou YJ,Zhou H,Li Y,Song YL

    更新日期:2012-12-01 00:00:00

  • [From external to implantable insulin pump, can we close the loop?].

    abstract::The project to finalize a 'closed loop' insulin delivery according to blood glucose level, i.e. an implanted artificial beta cell, is born from the development of the first miniaturized portable insulin pumps during the 1970s. Continuous improvements in micro-electronics, as well as in the development of biomaterials ...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:

    authors: Renard E,Costalat G,Bringer J

    更新日期:2002-09-01 00:00:00

  • Factors associated with reaching or not reaching target HbA1c after initiation of basal or premixed insulin in patients with type 2 diabetes.

    abstract:AIMS:To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA1c) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as basal hyperglycaemia, vs postprandial hyperglycaemia (PHG) before and after initiation of a basal or premixed insuli...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabet.2016.10.005

    authors: Scheen AJ,Schmitt H,Jiang HH,Ivanyi T

    更新日期:2017-02-01 00:00:00

  • Relationship between the hyperinsulinemic-euglycaemic clamp and a new simple index assessing insulin sensitivity in overweight and obese postmenopausal women.

    abstract:OBJECTIVE:The purpose of this study was to compare assessment of insulin sensitivity from hyperinsulinemic euglycaemic (HIEG) clamp with indexes derived from fasting and oral glucose tolerance test (OGTT). SUBJECTS AND METHODS:Cross-sectional study with 107 sedentary non-diabetic overweight and obese postmenopausal (B...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2007.02.004

    authors: Bastard JP,Vandernotte JM,Faraj M,Karelis AD,Messier L,Malita FM,Garrel D,Prud'homme D,Rabasa-Lhoret R

    更新日期:2007-09-01 00:00:00

  • Therapeutic approach of type 2 diabetes mellitus with GLP-1 based therapies.

    abstract::The goal of this review is to think about how to incorporate the GLP-1 based agents, represented by the dipeptidyl peptidase-4 (DPP-4) inhibitors or the glucagon-like peptide-1 (GLP-1) analogs, in the guidelines for the management of type 2 diabetes (T2DM). Orally administered DPP-4 inhibitors, such as sitagliptin and...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:10.1016/S1262-3636(08)73399-8

    authors: Penfornis A,Borot S,Raccah D

    更新日期:2008-02-01 00:00:00

  • Harnessing the incretin system beyond glucose control: potential cardiovascular benefits of GLP-1 receptor agonists in type 2 diabetes.

    abstract::The management of type 2 diabetes continues to evolve as new data emerge. Although glycaemic control is still important, other risk factors--such as hypertension, dyslipidaemia and obesity--must also be addressed in order to reduce the long-term risks of cardiovascular complications and mortality. In this context, tar...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabet.2012.04.003

    authors: Cariou B

    更新日期:2012-10-01 00:00:00

  • Trajectories of fasting plasma glucose variability and mortality in type 2 diabetes.

    abstract:AIM:To investigate the effect of changes in fasting plasma glucose (FPG) variability, as assessed by 2-year trajectories of FPG variability, on mortality risk in patients with type 2 diabetes (T2D). METHODS:From 2009 to 2012, outpatients with T2D, aged>18 years, were enrolled from a medical centre. FPG was measured ev...

    journal_title:Diabetes & metabolism

    pub_type: 杂志文章

    doi:10.1016/j.diabet.2017.09.001

    authors: Lee CL,Sheu WH,Lee IT,Lin SY,Liang WM,Wang JS,Li YF

    更新日期:2018-03-01 00:00:00