Abstract:
INTRODUCTION:Laparoscopic partial nephrectomy (LPN) has not received widespread clinical application because of its technical challenge. Bovine serum albumin glutaraldehyde (BSAG) is a hemostatic agent that is independent of the clotting cascade. We evaluated the use of BSAG as the sole agent for parenchymal and collecting system closure during LPN in a survival porcine model. METHODS:Eighteen pigs underwent hilar clamping and LPN by longitudinal excision of the lateral one-third of the right kidney. The opened collecting system was covered with oxidized cellulose to prevent BSAG seepage into the urinary tract. BSAG was allowed to set for 10 or 5 minutes. Twelve animals underwent survival LPN BSAG only closure; six control pigs were acutely studied using saline. Urinary extravasation was evaluated by injection of furosemide and indigo carmine, and then evaluating the renal surface and bladder catheter drainage for dye. A subjective bleeding score was assigned after hilum unclamping. At 6 weeks, BSAG kidneys were harvested for burst pressure testing and histopathological analysis. RESULTS:All 12 pigs survived for 6 weeks. No pigs had urinary extravasation. Mean percentage of kidney removed by weight was 19%. Mean warm ischemia time was 29 minutes. Five pigs required a second BSAG application to achieve a bleeding score of 0. Mean arterial and collecting system burst pressures were 301.8 and 322.4 mm Hg, respectively. Mean postoperative creatinine increase was 0.07 mg/dL. CONCLUSION:BSAG for completely sutureless LPN in a survival porcine model was feasible.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Louie MK,Gamboa AJ,Kaplan AG,Khosravi A,Truong H,Andrade L,Lin R,Alipanah R,Ortiz C,McCormick D,Box GN,Lee HJ,Deane LA,Edwards RA,McDougall EM,Clayman RVdoi
10.1089/end.2009.0200subject
Has Abstractpub_date
2010-03-01 00:00:00pages
451-5issue
3eissn
0892-7790issn
1557-900Xjournal_volume
24pub_type
杂志文章abstract:PURPOSE:We present a series of cystinuric patients with renal cystine calculi between 1.5 and 3.0 cm treated with retrograde renoscopy and intracorporeal lithotripsy and report our results, complications, and inpatient utilization with this approach. PATIENTS AND METHODS:The hospital and office charts of five consecut...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.1999.13.483
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Kidney stone disease is rare in the South African black (B) population and more prevalent in the white (W) population. Genetic studies have not previously examined this anomaly. The AGT Pro11Leu polymorphism in the alanine:glyoxylate aminotransferase (AGT) enzyme has been suggested as possibly pl...
journal_title:Journal of endourology
pub_type: 杂志文章
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journal_title:Journal of endourology
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journal_title:Journal of endourology
pub_type: 杂志文章
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journal_title:Journal of endourology
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pub_type: 杂志文章
doi:10.1089/end.2004.18.715
更新日期:2004-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.1993.7.389
更新日期:1993-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To evaluate the safety and efficacy of percutaneous nephrolithotomy (PCNL) for the management of complete staghorn calculi in children journal_title:Journal of endourology pub_type: 杂志文章 doi:10.1089/end.2005.19.968 更新日期:2005-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2018.0722
更新日期:2019-07-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903772036154
更新日期:2003-12-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2006-09-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.749
更新日期:2000-11-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2020-11-16 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章,meta分析,评审
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更新日期:2012-11-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1998.12.341
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:1999-05-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0319
更新日期:2018-08-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Journal of endourology
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:During laparoscopic nephrectomy (LPN), a stapling device is often used for vascular control, especially of the renal vein. Herein, we report our experience using a polymer clip (Hem-o-lok) for routine control of the vessels during LPN in the animal and clinical setting. PATIENTS AND METHODS:Fift...
journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00