Abstract:
:Respiratory syncytial virus (RSV) is recognized as an important cause of childhood morbidity and mortality. Vaccine development has been challenging in young infants and has required the advent of molecular technologies to optimize the safety profile, while maintaining immunogenicity of live-attenuated vaccines. Protein-based vaccines have been evaluated in clinical trials and are promising candidates for RSV-primed populations or for maternal vaccination to provide early life protection. This review provides a summary of the need for an RSV vaccine, as well as the challenges and progress in the vaccine's development.
journal_name
Paediatr Child Healthjournal_title
Paediatrics & child healthauthors
Sales V,Wang EEdoi
10.1093/pch/8.10.605subject
Has Abstractpub_date
2003-12-01 00:00:00pages
605-8issue
10eissn
1205-7088issn
1918-1485journal_volume
8pub_type
杂志文章abstract:OBJECTIVE:To determine the current prevalence of smoking among First Nations youth living on reserve within the Saskatoon Tribal Council, and to determine the independent risk indicators associated with smoking among First Nations youth. METHODS:Students in grades 5 to 8 attending school within the Saskatoon Tribal Co...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/16.10.e71
更新日期:2011-12-01 00:00:00
abstract::Children with acute asthma exacerbations frequently present to an emergency department with signs of respiratory distress. The most severe episodes are potentially life-threatening. Effective treatment depends on the accurate and rapid assessment of disease severity at presentation. This statement addresses the assess...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/17.5.251
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:In September 2005, the Alberta government introduced the daily physical activity (DPA) initiative, which requires that students from grades 1 to 9 be physically active in school for a minimum of 30 min per day. OBJECTIVE:To obtain information on whether and how the DPA initiative has been implemented in C...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/15.7.e19
更新日期:2010-09-01 00:00:00
abstract::Bone marrow aspiration (BMA) and bone marrow trephine biopsy are important procedures for the diagnosis of hematological malignancies and nonmalignant diseases in children. During BMA, bone marrow particles are obtained for analysis including microscopic morphologic evaluations and differential counts. During a trephi...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/13.6.499
更新日期:2008-07-01 00:00:00
abstract::Maintenance of plasma glucose depends on a normal endocrine system, functional enzyme levels for glycogenolysis, gluconeogenesis and other processes, and there must be an adequate supply of endogenous fat, glycogen and substrates of gluconeogenesis. Neonatal hypoglycemia should be defined as serum glucose less than 2....
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/3.1.16
更新日期:1998-01-01 00:00:00
abstract::Paediatric restless legs syndrome (RLS) treatment is important because RLS's associated sleep disturbance causes significant developmental-behavioural morbidity and impacts family well-being. RLS is associated with brain iron insufficiency and dopaminergic dysfunction. Diagnosis requires fulfillment of diagnostic crit...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/17.4.193
更新日期:2012-04-01 00:00:00
abstract:Background:Referrals to paediatric endocrine clinics for short stature are common. Height velocity (HV) is an essential component of the evaluation of short stature as growth deceleration often reflects an underlying paediatric endocrine diagnosis (PED). Access to previous measurements facilitates prompt calculation of...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy079
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:To explore how and when chiropractors are involved in the care of patients younger than 18 years of age, and to examine chiropractors' beliefs about treating paediatric patients. DESIGN:A cross-sectional survey of a random sample of 140 chiropractors practising in Alberta. Data were collected by means of a ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/6.7.433
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:A checklist that promotes compliance with aseptic technique during line insertion is a component of many care bundles aimed at reducing nosocomial infections among intensive care unit patients. OBJECTIVE:To determine whether the use of bundled interventions that include a checklist during central-line inser...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/19.4.e20
更新日期:2014-04-01 00:00:00
abstract::Nutrition for Healthy Term Infants is the new national statement on nutrition for infants from birth to 24 months, developed collaboratively by the Canadian Paediatric Society, Dietitians of Canada and Health Canada.The document summarizes the existing scientific literature on infant nutrition and presents principles ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/3.2.109
更新日期:1998-03-01 00:00:00
abstract:Aim:To investigate the implementation of amplitude-integrated electroencephalography (aEEG) as bedside monitoring tool of cerebral function in tertiary Canadian Neonatal Intensive Care Units (NICU) over the past decade. Methods:Longitudinal study consisting of online surveys of neonatologists on the use of aEEG in 200...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz091
更新日期:2019-10-10 00:00:00
abstract::Parents of children with type 1 diabetes commonly worry about the ability of school personnel to respond to their child's diabetes needs, and may feel anxious about the health, safety and inclusion of their child in school. Physicians may be confronted by parents' fears, anxieties and apprehension, and need to know ho...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/10.1.25
更新日期:2005-01-01 00:00:00
abstract::Although acute and subacute lead toxicity requiring active treatment is rare in Canada, paediatricians need to be aware of new evidence linking lower lead levels to neurodevelopmental deficits. Health Canada has identified potential exposures occurring prenatally, in infancy and during early childhood from food and wa...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxz080
更新日期:2019-07-01 00:00:00
abstract::In the face of negative media attention, community members and Elders from the First Nation community of Maskwacis identified the importance of promoting community strengths and reframing perceptions of their community. Two research questions were addressed: (1) How do youth in Maskwacis view their community strengths...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxx178
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Child abuse and neglect (CAN) represents an international public health and societal problem, the extent and nature of which are inadequately understood. Child and youth protection programs (CYPPs), based in 16 Canadian paediatric academic health science centres, identify, manage, treat and prevent cases of ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::Respite care is one integral component of the transition process from paediatric to adult health care, and is of particular importance to individuals with medical complexities. Numerous gaps that exist within the current system limit a child and family's ability to access quality respite care during a time when it is ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxx142
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Paediatrician human resource planning in Canada is currently a major concern. The optimal mix of physicians by type of practice and geographical distribution also remains controversial for many groups of physicians. OBJECTIVE:To compare 10-year trends (1987 to 1997) in paediatric practice with respect to ag...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/10.10.595
更新日期:2005-12-01 00:00:00
abstract::Child sexual abuse is an important and not uncommon problem. Children who have been sexually abused may present to a physician's office, urgent care centre, or emergency department for medical evaluation. A medical evaluation can provide reassurance to both child and caregiver, identify care needs, and offer an accura...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/pxaa019
更新日期:2020-04-01 00:00:00
abstract:Background:Functional abdominal pain disorders (FAPD) are prevalent in the paediatric population, however, there is currently no consensus regarding best practices for treatment. The use of probiotics is becoming popular to treat FAPD. The goal of this rapid review is to synthesize the best evidence on the use of probi...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/pxz036
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a multidisciplinary paediatric asthma clinic in reducing the morbidity associated with paediatric asthma. METHODS:An initial survey of need was undertaken in the community of Orillia, Ontario and the surrounding area. The clinic was established as a separate entity from the a...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/9.3.159
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:A checklist that promotes compliance with aseptic technique during line insertion is a component of many care bundles aimed at reducing nosocomial infections among intensive care unit patients. OBJECTIVE:To determine whether the use of bundled interventions that include a checklist during central-line inser...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/19.4.176
更新日期:2014-04-01 00:00:00
abstract::Family physicians, paediatricians, nurse practitioners and all primary health care providers are well-positioned in the health care system to provide identification and intervention for developmental delay in early childhood. This can be accomplished through the promotion of healthy child development by supporting chi...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/13.10.845
更新日期:2008-12-01 00:00:00
abstract::Widespread varicella vaccination in Canada since 2007 has changed the epidemiology of chickenpox, with a significant decline in varicella-related hospitalizations. However, there will always be a varicella-susceptible population because of immune-compromising treatments or conditions and/or parental vaccine refusal. T...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/pxy096
更新日期:2018-09-01 00:00:00
abstract::Recreation, globalization, migration, and families visiting friends and relatives (VFRs) overseas have increased the frequency of international travel and potential exposures to tropical diseases. Young infected patients can present a diagnostic challenge to clinicians when they return to Canada, with significant cons...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy138
更新日期:2018-12-01 00:00:00
abstract::Sexual and reproductive health is an important component of comprehensive health care for youth. This statement provides guidance for selecting and prescribing contraceptives for youth, including commonly prescribed hormonal contraceptives-the pill, patch, ring and injectable progestin-and long-acting reversible contr...
journal_title:Paediatrics & child health
pub_type: 杂志文章,评审
doi:10.1093/pch/pxx192
更新日期:2018-07-01 00:00:00
abstract::Hydrogenation of fat products is used in the food industry to extend their shelf life. Trans fats are the result of partial hydrogenation of unsaturated fat. Trans fats increase low-density lipoprotein cholesterol and decrease high-density lipoprotein cholesterol, thus increasing the risk of cardiovascular disease. Ca...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/15.6.373
更新日期:2010-07-01 00:00:00
abstract::The New England Journal of Medicine recently featured an original research article, 'Contemporary Hormonal Contraception and the Risk of Breast Cancer'. (Source: Mørch LS, Skovlund CW, Hannaford PC, Iversen L, Fielding S, Lidegaard Ø. Contemporary hormonal contraception and the risk of breast cancer. N Engl J Med 2017...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxy169
更新日期:2019-07-01 00:00:00
abstract:Introduction:In June 2012, the government of Canada severely restricted the scope of the Interim Federal Health Program that had hitherto provided coverage for the health care needs of refugee claimants. The Quebec government decided to supplement coverage via the provincial health program. Despite this, we hypothesize...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/pxx115
更新日期:2017-11-01 00:00:00
abstract::Details of an innovative model for providing health education to families and patients using a coordinated series of skill-based educational opportunities are described. The model offers a variety of educational courses for parents of children at each developmental stage. Each course provides transferable skills that ...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/5.6.329
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:To determine the use and potential interactions of natural health products (NHPs) with conventional medications in children with life-limiting illnesses. METHODS:The present study was a retrospective medical record review of palliative care patients <18 years of age who were admitted for respite care to a C...
journal_title:Paediatrics & child health
pub_type: 杂志文章
doi:10.1093/pch/20.1.23
更新日期:2015-01-01 00:00:00