Respiratory syncytial virus vaccine: Is it coming?

Abstract:

:Respiratory syncytial virus (RSV) is recognized as an important cause of childhood morbidity and mortality. Vaccine development has been challenging in young infants and has required the advent of molecular technologies to optimize the safety profile, while maintaining immunogenicity of live-attenuated vaccines. Protein-based vaccines have been evaluated in clinical trials and are promising candidates for RSV-primed populations or for maternal vaccination to provide early life protection. This review provides a summary of the need for an RSV vaccine, as well as the challenges and progress in the vaccine's development.

journal_name

Paediatr Child Health

authors

Sales V,Wang EE

doi

10.1093/pch/8.10.605

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

605-8

issue

10

eissn

1205-7088

issn

1918-1485

journal_volume

8

pub_type

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