Abstract:
:To clarify how lung function at exercise is affected in sarcoidosis, and to analyze how exercise studies compare to testing measurements, 63 patients with pulmonary sarcoidosis were examined with lung mechanics and arterial blood gases during exercise. These findings were compared with simultaneously obtained, but previously reported results of the static lung pressure/volume curve and the lung resistance/static lung pressure curve. While mechanical variables at maximal exercise were as sensitive as those determined by measuring the PstL/V and RL/PstL curves, mechanics during spontaneous breathing at rest was less sensitive. The derangement of mechanics was more evident than that of arterial blood gases. No measurement at rest was a good predictor of working capacity or of arterial PaO2. A comprehensive exercise examination may be an alternative to resting investigations, which are either more elaborate or less sensitive.
journal_name
Chestjournal_title
Chestauthors
Brådvik I,Wollmer P,Blom-Bülow B,Albrechtsson U,Jonson Bdoi
10.1378/chest.99.3.572subject
Has Abstractpub_date
1991-03-01 00:00:00pages
572-8issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(16)30921-7journal_volume
99pub_type
杂志文章相关文献
CHEST文献大全abstract:PURPOSE:The aim of this study was to assess the usefulness of a specific inspiratory muscle training in Duchenne muscular dystrophy (DMD). PATIENTS AND METHODS:Fifteen patients with DMD started 6 months of training the inspiratory muscles and 15 patients served as a control group. Pulmonary and inspiratory muscle func...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.105.2.475
更新日期:1994-02-01 00:00:00
abstract:STUDY OBJECTIVES:To determine if persistent airway tissue mast cells are associated with treatment failure when patients discontinue inhaled corticosteroids (ICS). DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:Multicenter, tertiary referral centers. PATIENTS OR PARTICIPANTS:Forty-five subjects w...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.124.1.42
更新日期:2003-07-01 00:00:00
abstract::Chronic heart failure (CHF) is a complex syndrome affecting many body systems. Body wasting (ie, cardiac cachexia) is a serious complication of CHF long known but little investigated. Although no specific diagnostic criteria have been established, we have suggested that cardiac cachexia be defined on the basis of the ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.115.3.836
更新日期:1999-03-01 00:00:00
abstract::A patient had accelerated attacks of chest pain associated with transient ST elevation or depression in the anterior leads. Coronary angiogram revealed severe multi-vessel disease. Anginal attacks with conspicuous ST depression were induced repeatedly by both oral and sublingual administration of nifedipine. Among var...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.81.5.646
更新日期:1982-05-01 00:00:00
abstract::The echocardiographic appearance of fungal endocarditis of the aortic valve is described in a patient who subsequently died from this disease. In addition, the progressive growth of the vegetation on serial echocardiograms was recorded, and premature closure of the mitral valve was absent, notwithstanding perforation ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.2.300
更新日期:1976-08-01 00:00:00
abstract::Exacerbations of sarcoidosis are common. In particular, exacerbations of pulmonary sarcoidosis are reported in more than one-third of patients. Despite their frequent occurrence, there is little medical evidence concerning the definition, diagnosis, and treatment of pulmonary exacerbations of sarcoidosis. In this arti...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.12-1060
更新日期:2012-10-01 00:00:00
abstract::We report a patient in whom cardiac magnetic resonance imaging detected a clinically unsuspected pulmonary artery thromboembolus. Follow-up MRI after surgical removal of the thromboembolus showed normal pulmonary arteries. This case illustrates the potential utility of MRI in the detection and follow-up of central pul...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.1.232
更新日期:1989-01-01 00:00:00
abstract::Closure of ventricular septal defects through the aortic valve annulus has been described for a variety of cardiac anomalies. This technique is most appropriate when simultaneous aortic valve replacement is anticipated. A continuous suture through the patch material may produce a purse-string effect upon the aortic va...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.2.311
更新日期:1976-08-01 00:00:00
abstract:STUDY OBJECTIVES:COPD patients run a risk of developing nocturnal oxygen desaturation. When evaluating patients with nocturnal hypoxemia, an unfamiliar hospital environment and the monitoring equipment may cause sleep disturbances. It was hypothesized that increased sleep disruption will lead to fewer instances of desa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.119.6.1820
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Data on patients with cancer who have a prolonged length of stay (LOS) in the ICU are scarce. The aim of the present study was to evaluate the characteristics and the outcomes of cancer patients with life-threatening complications with an ICU stay > or = 21 days. METHODS:A cohort study performed at a 10-bed...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-0359
更新日期:2008-09-01 00:00:00
abstract::Epidemiologic research has revealed a substantial portion of the general population with abnormal spirometry results that are characterized by decreased FEV1 and FVC but a preserved FEV1/FVC ratio. This restrictive spirometry pattern (RSP) is inconsistently defined in the literature and not well addressed by current g...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.15-1045
更新日期:2016-01-01 00:00:00
abstract::The ST alternans was recorded during at least one ischemic attack with ST elevation in nine of 65 patients with variant angina. The magnitude and duration of ST elevation during ischemic attacks were significantly greater in patients with than in those without ST alternans. It always appeared during the occlusion phas...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.93.3.587
更新日期:1988-03-01 00:00:00
abstract::Cidofovir, a nucleoside analog antiviral agent, has been used with moderate success in the treatment of juvenile laryngeal papillomatosis (JLP) by direct intralesional injection. We report the first case where IV cidofovir was used successfully to treat a rare but lethal multicystic lung disease complicating JLP. A 35...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.118.4.1210
更新日期:2000-10-01 00:00:00
abstract:STUDY OBJECTIVES:Clinical prediction models for the diagnosis of obstructive sleep apnea (OSA) have lacked the accuracy necessary to confidently replace polysomnography (PSG). Artificial neural networks are computer programs that can be trained to predict outcomes based on experience. This study was conducted to test t...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.2.409
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Dynamic hyperinflation (DH) develops in patients with COPD during incremental exercise with a cycle ergometer. The aims of this study were to determine whether DH can be evidenced after walking with a handheld spirometer and to determine its functional consequences. METHODS:Fifty patients with COPD (39 men;...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-0410
更新日期:2009-12-01 00:00:00
abstract::We wished to identify the physiologic abnormalities that distinguish severely breathless (SB) patients with chronic airflow limitation (CAL) from mildly breathless (MB) patients. Thirty-seven patients with stable, advanced CAL (FEV1 = 38 +/- 10 percent predicted, mean +/- SD) were separated into two distinct groups, S...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.3.824
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:An obesity paradox, wherein patients who are obese have lower mortality, has been described in cardiopulmonary diseases, including pulmonary arterial hypertension (PAH). Our objective was to determine whether obesity and BMI are associated with mortality in patients with PAH. METHODS:We assessed incident pa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2018.05.006
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Studies have demonstrated that high-flow nasal cannula (HFNC) prevents intubation in acute hypoxic respiratory failure when compared with conventional oxygen therapy (COT). However, the data examining routine HFNC use in the immediate postoperative period are less clear. RESEARCH QUESTION:Is routine HFNC us...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.06.038
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Small cell lung carcinoma (SCLC) continues to have a poor prognosis, with a 2-year survival of < 20%. Studies have suggested that SCLC may affect the immune system to allow it to evade immunologic responses. We hypothesized that any such effect would be characterized by a decrease in the lymphoid cells assoc...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-0681
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Increased expression of the human epididymis protein 4 (HE4) was previously described in lung biopsy samples from patients with cystic fibrosis (CF). It remains unknown, however, whether serum HE4 concentrations are elevated in CF. METHODS:Seventy-seven children with CF from six Hungarian CF centers and 57 ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.04.006
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:A comprehensive evaluation of temporal trends in the treatment of patients who have DVT may assist with identification of modifiable factors that contribute to short-term outcomes. METHODS:We assessed temporal trends in length of hospital stay and use of pharmacological and interventional therapies among 26...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.03.046
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Both pulmonary hypertension and pulmonary overflow are associated with functional and structural changes of the pulmonary arterial wall. Current techniques to evaluate the pulmonary vasculature neglect the pulsatile nature of pulmonary flow. STUDY OBJECTIVES:To determine whether the dynamic properties of th...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.2.549
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:We hypothesized that breathing helium-hyperoxia (HeO2) would significantly improve 6-min walking test (6MWT) distance in COPD subjects. METHODS:This was a blinded, randomized crossover study. At visit 1, we assessed pulmonary function, exercise capacity, and 6MWT distance. Visits 2 and 3 consisted of four 6...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.06-2514
更新日期:2007-06-01 00:00:00
abstract::We describe two patients with histologically proven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.5.1452
更新日期:1999-05-01 00:00:00
abstract::In 14 consecutive patients with varying myocardial function, evaluation of the Valsalva maneuver was performed using aortic pulse pressure decay to investigate a possible quantitative relationship between the pattern of response and the degree of myocardial dysfunction. The aortic pulse pressure response during strain...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.5.986
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to determine the prevalence of Aspergillus fumigatus and Candida albicans in the sputa of patients with cystic fibrosis (CF), to assess serologic IgE responses of these patients to the presence of fungi in the sputum, to evaluate what effect this may have on clinical status,...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.121.3.782
更新日期:2002-03-01 00:00:00
abstract::Colloid osmotic pressure (COP) was measured serially in 81 critically ill neonates with hyaline membrane disease (HMD) during the first five days of life, and these changes were correlated with the birth weight, gestational age, serum protein level, clinical status, and outcome. Colloid osmotic pressure correlated bet...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.83.5.776
更新日期:1983-05-01 00:00:00
abstract:BACKGROUND:The aim of this study was to characterize the practice of routinely obtaining tracheal aspirate cultures in children with tracheostomy tubes and to analyze the appropriateness of using this information to guide antibiotic selection for treatment of subsequent lower respiratory infections. METHODS:Pediatric ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2539
更新日期:2012-03-01 00:00:00
abstract:STUDY OBJECTIVE:To determine if animals with abnormally low albumin levels are more susceptible to the effects of hypercapnia on BP compared to normal animals. DESIGN:Prospective, controlled laboratory experiment. SETTING:University research laboratory. ANIMALS:Eighteen male Sprague-Dawley rats: 6 rats 10 to 12 week...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.06-2069
更新日期:2007-05-01 00:00:00
abstract::The spontaneous variability of arterial blood gas and pH values (ABGs) was examined in a group of 28 typical stable medical ICU patients under a variety of ventilatory conditions. In each patient, 13 ABG specimens were measured at 5-min intervals during a 1-h study period using a new bedside, extravascular fluorescent...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.1.187
更新日期:1994-07-01 00:00:00