Safety and effectiveness of bivalirudin in routine care of patients undergoing percutaneous coronary intervention.

abstract：AIMS:Reperfusion injury following acute myocardial infarction impacts not only on the myocardium but also on the coronary microcirculation, and microembolization from the culprit lesion contributes to microvascular obstruction. Prior experimental studies have not accounted for microembolization in ischaemia/reperfusion...

journal_title：European heart journal

authors： Skyschally A,Walter B,Heusch G

更新日期：2013-11-01 00:00:00

abstract：AIMS:We sought to assess the effect of clopidogrel on clinical events 1 year after discharge in survivors of ST-elevation myocardial infarction (STEMI) in clinical practice. METHODS AND RESULTS:We analysed data of consecutive survivors of acute STEMI and either concomitant therapy with aspirin or aspirin plus clopidog...

journal_title：European heart journal

authors： Zeymer U,Gitt AK,Jünger C,Heer T,Wienbergen H,Koeth O,Bauer T,Mark B,Zahn R,Gottwik M,Senges J,Acute COronary Syndromes (ACOS) registry investigators.

更新日期：2006-11-01 00:00:00

abstract：AIMS:In end-stage heart failure, an alteration in the expression of the Na+-Ca2+ exchanger has been reported. Regulation of its expression is largely unknown. We sought to find out whether Na+-Ca2+ exchanger in human heart failure is regulated by sympathetic activation. In addition, since Na+-Ca2+-exchange is electroge...

journal_title：European heart journal

authors： Schillinger W,Schneider H,Minami K,Ferrari R,Hasenfuss G

更新日期：2002-07-01 00:00:00

abstract：:This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causati...

journal_title：European heart journal

authors： Wendler D,Mendoza E,Schleiffer T,Zander M,Maier M

更新日期：1995-03-01 00:00:00

abstract：:One case of unruptured sinus of Valsalva aneurysm causing left coronary artery compression and lethal myocardial infarction in a 39-year old woman is described. In reviewing the literature, 15 previously published cases of sinus of Valsalva aneurysms disturbing coronary flow were found. It is concluded that the mechan...

journal_title：European heart journal

authors： Brandt J,Jögi P,Lührs C

更新日期：1985-12-01 00:00:00

abstract：AIMS:Quantitative analysis of rest-stress myocardial perfusion magnetic resonance imaging (MRI) can provide assessments of regional myocardial perfusion reserve (MPR). The purpose of this study was to compare regional MPR determined by myocardial perfusion MRI with coronary flow reserve (CFR) by intracoronary Doppler f...

journal_title：European heart journal

authors： Kurita T,Sakuma H,Onishi K,Ishida M,Kitagawa K,Yamanaka T,Tanigawa T,Kitamura T,Takeda K,Ito M

更新日期：2009-02-01 00:00:00

abstract：AIMS:Little research exists on exercise performance and training in patients with an implemented cardioverter defibrillator (ICD) and only in a limited number of patients. This study aims to investigate the effect of exercise training in ICD patients in comparison to the effects in other cardiac patients without an ICD...

journal_title：European heart journal

authors： Vanhees L,Kornaat M,Defoor J,Aufdemkampe G,Schepers D,Stevens A,Van Exel H,Van Den Beld J,Heidbüchel H,Fagard R

更新日期：2004-07-01 00:00:00

abstract：:Atrial fibrillation is a frequent cause of stroke; in the elderly, more than 20% of strokes are attributed to this common arrhythmia. Anticoagulation with warfarin reduces the risk of stroke by ∼60%; however, a large proportion of patients with atrial fibrillation do not receive this treatment because of relative/abso...

journal_title：European heart journal

authors： Landmesser U,Holmes DR Jr

更新日期：2012-03-01 00:00:00

abstract：AIMS:Transthyretin amyloidosis (ATTR amyloidosis) is a heterogeneous disorder with cardiac, neurologic, and mixed phenotypes. We describe the phenotypic and genotypic profiles of this disease in continental Western Europe as it appears from the Transthyretin Amyloidosis Survey (THAOS). METHODS AND RESULTS:THAOS is an ...

journal_title：European heart journal

authors： Damy T,Kristen AV,Suhr OB,Maurer MS,Planté-Bordeneuve V,Yu CR,Ong ML,Coelho T,Rapezzi C,THAOS Investigators.

更新日期：2019-04-01 00:00:00

abstract：AIMS:Obstructive sleep apnoea (OSA) is highly prevalent in patients with chronic heart failure (CHF) and may contribute to CHF progression. We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients...

journal_title：European heart journal

authors： Smith LA,Vennelle M,Gardner RS,McDonagh TA,Denvir MA,Douglas NJ,Newby DE

更新日期：2007-05-01 00:00:00

abstract：:Despite therapeutic improvements, cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, fluids, adjunctive medication, intra-aortic balloon counterpulsation, and also assist devices are widely used...

journal_title：European heart journal

authors： Thiele H,Allam B,Chatellier G,Schuler G,Lafont A

更新日期：2010-08-01 00:00:00

abstract：:I.S.A.M. was a prospective, placebo-controlled, double-blind multicentre trial of high-dose short-term intravenous streptokinase in acute myocardial infarction (AMI) within 6 h of the onset of symptoms. Determination of left ventricular ejection fraction (LVEF) by radionuclide ventriculography was performed 1 and 7 mo...

journal_title：European heart journal

authors： Voth E,Tebbe U,Schicha H,Neumann P,Schröder R,Neuhaus KL,Emrich D

更新日期：1990-10-01 00:00:00

abstract：:In the interpretation of the effect of a drug or intervention in a single patient, it is desirable to know the spontaneous fluctuations of the variable under study. A few studies have determined pulmonary haemodynamic variability in acute and short-term intervals. It seems reasonable to adopt a confidence limit of 6 m...

journal_title：European heart journal

authors： Schrijen F,Jezková J

更新日期：1988-09-01 00:00:00

abstract：:A twenty-first century model for the training and assessment of cardiac interventionists’ skills, outlined by Prof. John Morgan FRCP FESC. ...

journal_title：European heart journal

authors： Morgan JM,Burri H,Binner L,Mansour H,Retzlaff H,Roca M,Gallagher A

更新日期：2011-01-01 00:00:00

abstract：AIMS:The role of cardiovascular risk factors and atherosclerosis in the aetiology of abdominal aortic aneurysms is not well understood. The aim of this study was to determine the association between atherosclerosis and aortic aneurysm in the general population and the extent to which cardiovascular risk factors might i...

journal_title：European heart journal

authors： Lee AJ,Fowkes FG,Carson MN,Leng GC,Allan PL

更新日期：1997-04-01 00:00:00

abstract：:For clinical prognosis, LV function is best described in terms of ejection fraction (EF) or end-systolic volume (ESV). Because deterioration of LV function is the most important adverse prognostic factor for patients after recovery from myocardial infarction, any agent which improves function should improve long-term ...

journal_title：European heart journal

authors： Norris RM,White HD

更新日期：1990-08-01 00:00:00

abstract：AIMS:Recent data suggest that the administration of bone marrow-derived stem cells (BMSC) might improve myocardial perfusion and left ventricular (LV) function after acute myocardial infarction (AMI). The aim of this study was to assess spontaneous mobilization of BMSC expressing the haematopoietic and endothelial prog...

journal_title：European heart journal

authors： Leone AM,Rutella S,Bonanno G,Abbate A,Rebuzzi AG,Giovannini S,Lombardi M,Galiuto L,Liuzzo G,Andreotti F,Lanza GA,Contemi AM,Leone G,Crea F

更新日期：2005-06-01 00:00:00

abstract：:The left atrial appendage (LAA) is the main source of thromboembolism in patients with non-valvular atrial fibrillation (AF). As such, the LAA can be the target of specific occluding device therapies. Optimal management of patients with AF includes a comprehensive knowledge of the many aspects related to LAA structure...

journal_title：European heart journal

authors： Patti G,Pengo V,Marcucci R,Cirillo P,Renda G,Santilli F,Calabrò P,De Caterina AR,Cavallari I,Ricottini E,Parato VM,Zoppellaro G,Di Gioia G,Sedati P,Cicchitti V,Davì G,Golia E,Pariggiano I,Simeone P,Abbate R,Prisco

更新日期：2017-03-21 00:00:00

abstract：:The implementation of molecular biological approaches has led to the discovery of single genetic variations that contribute to the development of cardiac failure. In the present review, the characteristics that are invariably associated with the development of failure in experimental animals and clinical studies are d...

journal_title：European heart journal

authors： Lips DJ,deWindt LJ,van Kraaij DJ,Doevendans PA

更新日期：2003-05-01 00:00:00

abstract：AIMS:To investigate the efficacy and safety of a cardiac resynchronization therapy with cardioverter-defibrillator (CRT-D) device with simplified ventricular tachycardia management in patients with non-ischaemic heart failure (HF) and primary prevention implantable cardioverter defibrillator (ICD) indication. METHODS ...

journal_title：European heart journal

authors： Gasparini M,Menozzi C,Proclemer A,Landolina M,Iacopino S,Carboni A,Lombardo E,Regoli F,Biffi M,Burrone V,Denaro A,Boriani G

更新日期：2009-11-01 00:00:00

abstract：:The slope and pressure half-time of the aortic regurgitant velocity spectrum have been used as non-invasive markers of regurgitant severity. Recent in vitro and theoretical work, however, has suggested a confounding effect of systemic vascular resistance and left ventricular compliance on these parameters. To study th...

journal_title：European heart journal

authors： Griffin BP,Flachskampf FA,Reimold SC,Lee RT,Thomas JD

更新日期：1994-05-01 00:00:00

abstract：:A 22-year-old man who engaged in intense and regular physical exercise complained of atypical chest pain. The only remarkable abnormality found in the routine clinical work-up was a left posterior hemiblock. The echocardiogram and the magnetic resonance imaging (MRI) study showed a tumour in the posterior and superior...

journal_title：European heart journal

authors： Cola H,Hoffman R,Borrega NG,Lazzari JO

更新日期：1992-04-01 00:00:00

abstract：AIMS:In acute coronary syndromes (ACS), the optimal revascularization strategy for unprotected left main coronary disease (ULMCD) has been little studied. The objectives of the present study were to describe the practice of ULMCD revascularization in ACS patients and its evolution over an 8-year period, analyse the pro...

journal_title：European heart journal

authors： Montalescot G,Brieger D,Eagle KA,Anderson FA Jr,FitzGerald G,Lee MS,Steg PG,Avezum A,Goodman SG,Gore JM,GRACE Investigators.

更新日期：2009-10-01 00:00:00

abstract：AIMS:Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence of comparative data among drug classes, we performed a retrospective study in 32 Health Services of 16 Italian regions accounting for a population of 18 million individuals, to assess the association between ...

journal_title：European heart journal

authors： Fadini GP,Avogaro A,Degli Esposti L,Russo P,Saragoni S,Buda S,Rosano G,Pecorelli S,Pani L,OsMed Health-DB Network.

更新日期：2015-09-21 00:00:00

abstract：:In a prospective trial in 124 patients with acute myocardial infarction, Holter and surface ECG recordings were obtained simultaneously and compared for their ability to assess thrombolysis-induced ST segment changes. Accuracy in predicting patency of the infarct-related artery was evaluated in both methods. Success o...

journal_title：European heart journal

authors： Zabel M,Hohnloser SH,Parussel A,Just H

更新日期：1992-12-01 00:00:00

abstract：:Morphological changes in human myocardium associated with pressure overload-induced left ventricular hypertrophy were studied in 22 normal and 21 hypertrophic hearts obtained at autopsy. Samples were obtained from the left lateral ventricular wall, half way between the apex and the base. Myocyte dimensions, polyploidi...

journal_title：European heart journal

authors： Vliegen HW,van der Laarse A,Cornelisse CJ,Eulderink F

更新日期：1991-04-01 00:00:00

abstract：:The mechanism of coronary spasm is poorly understood. We report a case of coronary artery spasm in a cardiac transplant patient. Pharmacologic testing indicated denervation of the patient's heart. Therefore coronary artery spasm may occur despite cardiac denervation. This case demonstrates that intact autonomic nervou...

journal_title：European heart journal

authors： Cattan S,Drobinski G,Artigou JY,Grogogeat Y,Cabrol C

更新日期：1988-05-01 00:00:00

abstract：AIMS:Although dilated cardiomyopathy is the most frequent form of cardiomyopathy, its aetiology is still poorly understood. In about 20-30% of cases the disease is familial with a large predominance of autosomal dominant transmission. Ten different chromosomal loci have been described for autosomal dominant forms of di...

journal_title：European heart journal

authors： Tesson F,Sylvius N,Pilotto A,Dubosq-Bidot L,Peuchmaurd M,Bouchier C,Benaiche A,Mangin L,Charron P,Gavazzi A,Tavazzi L,Arbustini E,Komajda M

更新日期：2000-11-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is associated with abnormal sarcoplasmic reticulum (SR) calcium release, which is promoted by adenosine A(2A) receptor (A(2A)R) activation. Here, we tested the hypothesis that abnormal calcium release in AF is linked to A(2A)R remodelling. METHODS AND RESULTS:Western blotting and quantita...

journal_title：European heart journal

authors： Llach A,Molina CE,Prat-Vidal C,Fernandes J,Casadó V,Ciruela F,Lluís C,Franco R,Cinca J,Hove-Madsen L

更新日期：2011-03-01 00:00:00

abstract：AIMS:Despite the known benefits of regular exercise, the reasons why many coronary heart disease (CHD) patients engage in little physical activity are not well understood. This study identifies factors associated with low activity levels in individuals with chronic CHD participating in the STABILITY study, a global cli...

journal_title：European heart journal

authors： Stewart R,Held C,Brown R,Vedin O,Hagstrom E,Lonn E,Armstrong P,Granger CB,Hochman J,Davies R,Soffer J,Wallentin L,White H

更新日期：2013-11-01 00:00:00