Feasibility and safety of transcatheter intervention for complex patent ductus arteriosus.

Abstract:

:We evaluated the transcatheter intervention of complex patent ductus arteriosus (PDA) in Chinese adults. Between January 2004 and April 2008, 112 adult patients (43 males, 69 females, mean age 31 +/- 19 years) underwent intervention. Coils were used for patients with small PDA, and Amplatzer duct occluders or China-made mushroom-shaped occluders were used for patients with moderate-to-large PDA. The success rate of transcatheter intervention was 93.8%, and 9 patients (8.0%) had small residual shunts. At the end of 12 months follow-up, the rate of residual shunts was 1.8%. Peak systolic pulmonary pressure decreased from 94 +/- 21 mm Hg preintervention to 58 +/- 20 mm Hg postintervention (P < .001). No severe procedure-related complications (including death, dislocation of occluders, stenosis of aorta or pulmonary artery) occurred. Some patients developed hemolysis or vascular access complications, all resolved by conservative therapy. Transcatheter intervention is an effective and safe treatment for adult PDA patients with complex anatomic or hemodynamic conditions.

journal_name

Angiology

journal_title

Angiology

authors

Yang SW,Zhou YJ,Hu DY,Liu YY,Shi DM,Guo YH,Cheng WJ,Nie XM,Wang JL

doi

10.1177/0003319709351874

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

372-6

issue

4

eissn

0003-3197

issn

1940-1574

pii

0003319709351874

journal_volume

61

pub_type

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