Abstract:
:The excitability of individual dendritic branches is a plastic property of neurons. We found that experience in an enriched environment increased propagation of dendritic Na(+) spikes in a subset of individual dendritic branches in rat hippocampal CA1 pyramidal neurons and that this effect was mainly mediated by localized downregulation of A-type K(+) channel function. Thus, dendritic plasticity might be used to store recent experience in individual branches of the dendritic arbor.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Makara JK,Losonczy A,Wen Q,Magee JCdoi
10.1038/nn.2428subject
Has Abstractpub_date
2009-12-01 00:00:00pages
1485-7issue
12eissn
1097-6256issn
1546-1726pii
nn.2428journal_volume
12pub_type
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