Implications for single phase prospective CT coronary angiography for the diagnosis of significant coronary stenoses in clinical practice.

Abstract:

BACKGROUND:CT coronary angiography (CTA) with 64 slice multi-detector CT (64-MDCT) has assumed an increasing role in clinical practice; however the high radiation dose associated with retrospective ECG-gated CTA has led to suggestions that a low dose prospectively gated strategy may be more appropriate. This study aims to assess the feasibility of this proposed strategy amongst standard referral for CTA in our centre. METHODS:We retrospectively analyzed 200 consecutive clinical CTA studies assessing the number of cardiac phases required to allow full diagnostic visualisation of the coronary tree. We assessed whether the pre-test likelihood of coronary disease, heart rate, heart rate variability and range, current beta-blockers use, coronary calcium score, breathing artefact or study quality affected the number of phases required. RESULTS:125/200 patients (62.5%) required only a single phase for full diagnostic visualisation of the coronary tree [most commonly 65% of the R-R interval-109/125 (87.2%)]. A successful diagnostic single cardiac phase was most likely in patients with a low heart rate (Heart rate < 70 bpm OR = 2.64; p = 0.003 and heart rate < 60 bpm OR = 4.81; p < 0.001 respectively) and low likelihood of coronary disease [OR = 1.97 95% CI (1.09, 3.58) p = 0.025]. CONCLUSION:High image quality is possible using single phase analysis in those patients with low likelihood of coronary disease, low heart rates and full cooperation with inspiratory breath hold. In patients with HR of <60, prospective ECG-gated acquisitions reduce radiation dose but may be non-diagnostic in as many as one third. Careful patient selection is therefore essential.

journal_name

Int J Cardiol

authors

Sá MI,Nicol ED,Stirrup J,Crean A,Roughton M,Padley SP,Rubens MB

doi

10.1016/j.ijcard.2009.09.542

subject

Has Abstract

pub_date

2011-03-17 00:00:00

pages

393-7

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(09)01486-7

journal_volume

147

pub_type

杂志文章
  • Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women.

    abstract:BACKGROUND:Lp(a), implicated in both atherogenesis and thrombosis pathways, varies significantly by demographic and metabolic factors, providing challenges for its use in Coronary Heart Disease (CHD) risk. The purpose of this study was to investigate whether type-2 diabetic subjects, relative to non-diabetics, might be...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2010.02.021

    authors: Qasim AN,Martin SS,Mehta NN,Wolfe ML,Park J,Schwartz S,Schutta M,Iqbal N,Reilly MP

    更新日期:2011-07-01 00:00:00

  • Incidence and impact of renal dysfunction on clinical outcomes after transcatheter aortic valve implantation.

    abstract:BACKGROUND:The impact of baseline renal dysfunction on early and late clinical outcomes after transcatheter aortic valve implantation (TAVI) remains to be defined. METHODS:927 patients included in the prospective Bern TAVI registry were classified on the basis of the baseline estimated glomerular filtration rate (eGFR...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.09.201

    authors: Franzone A,Stortecky S,Pilgrim T,Asami M,Lanz J,Heg D,Langhammer B,Piccolo R,Lee JKT,Praz F,Räber L,Valgimigli M,Roost E,Windecker S

    更新日期:2018-01-01 00:00:00

  • High incidence of subclinical atrial fibrillation in patients with syncope monitored with implantable cardiac monitor.

    abstract:OBJECTIVE:The use of implantable cardiac monitors (ICM) is highly useful in syncope workup. Latest-generation devices can detect asymptomatic episodes of atrial fibrillation. The main objective of this study was to determine the incidence of subclinical atrial fibrillation (AF) detected in a patient population undergoi...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2020.05.078

    authors: Francisco-Pascual J,Olivella San Emeterio A,Rivas-Gándara N,Pérez-Rodón J,Benito B,Santos-Ortega A,Moya-Mitjans À,Rodríguez García J,Llerena Butrón SI,Cantalapiedra Romero J,Ferreira González I

    更新日期:2020-10-01 00:00:00

  • My patient wants to perform strenuous endurance exercise. What's the right advice?

    abstract::Prolonged strenuous endurance exercise (SEE) such as marathon running has recently been associated with potential deleterious cardiac effects, particularly increased risk of atrial fibrillation (AF). This topic is medically important due to the increasing number of participants in SEE events lasting several hours, inc...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2015.06.014

    authors: Sanchis-Gomar F,Santos-Lozano A,Garatachea N,Pareja-Galeano H,Fiuza-Luces C,Joyner MJ,Lucia A

    更新日期:2015-10-15 00:00:00

  • Association between γ-glutamyltransferase level and incidence of atrial fibrillation: A nationwide population-based study.

    abstract:BACKGROUND:Information on the association between γ-glutamyltransferase (GGT) and the incidence of atrial fibrillation (AF) is scarce. We evaluated the association between GGT and AF incidence, and the interaction between GGT and obesity on developing AF in a large population-based cohort. METHODS:We evaluated 266,550...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.07.067

    authors: Lee SR,Choi EK,Han KD,Cha MJ,Oh S

    更新日期:2017-10-15 00:00:00

  • Effect of intravenous and oral flecainide on ventricular tachycardia.

    abstract::The effect of flecainide acetate, a class 1c antiarrhythmic agent, was examined in 15 patients with recurrent ventricular tachycardia. Intravenous flecainide was administered in a dose of 2 mg/kg at the time of intracardiac stimulation and recording studies. Oral flecainide was given to 10/15 patients and retesting wa...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(86)90007-0

    authors: Ward DE,Cheesman M,Dancy M

    更新日期:1986-03-01 00:00:00

  • Angiotensin receptor-neprilysin inhibitors: A new paradigm in heart failure with reduced ejection fraction.

    abstract::Despite significant advances in the last 30 years in reducing morbidity and mortality from heart failure with reduced ejection fraction (HFrEF) with pharmacological and device-based therapies, patients remain at a high risk of adverse cardiovascular outcomes. Sacubitril/valsartan, a first-in-class angiotensin receptor...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2018.05.124

    authors: Docherty KF,McMurray JJV

    更新日期:2019-04-15 00:00:00

  • Paroxysmal Mobitz type-I atrioventricular block Luciani-Wenckebach conduction, acute myocardial infarction and severe three vessels coronary artery disease.

    abstract::Paroxysmal atrioventricular block has been reported in patients without acute coronary syndrome and without significant coronary artery stenosis, in patients with acute coronary syndrome and without significant coronary artery stenosis, in patients without acute coronary syndrome and with significant coronary artery s...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2008.03.027

    authors: Patanè S,Marte F

    更新日期:2009-06-12 00:00:00

  • Peripartum cardiomyopathy in type II autoimmune polyendocrine syndrome.

    abstract::Autoimmune polyglandular syndromes (APS) consist of the failure of two or more endocrinal glands together requiring hormone replacement. Type II APS, first described by Schmidt in 1926, is the commonest type of APS. In majority of patients, type II APS consists of Addison's disease in combination with autoimmune thyro...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2009.03.020

    authors: Kumar KV,Pushkaraj SG,Krishnaleela BL,Modi KD

    更新日期:2011-05-19 00:00:00

  • Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations from the Cologne Consensus Conference 2018.

    abstract::Chronic thromboembolic pulmonary hypertension (CTEPH) is a subgroup of pulmonary hypertension that differs from all other forms of PH in terms of its pathophysiology, patient characteristics and treatment. For implementation of the European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension in Germany, th...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2018.08.079

    authors: Wilkens H,Konstantinides S,Lang IM,Bunck AC,Gerges M,Gerhardt F,Grgic A,Grohé C,Guth S,Held M,Hinrichs JB,Hoeper MM,Klepetko W,Kramm T,Krüger U,Lankeit M,Meyer BC,Olsson KM,Schäfers HJ,Schmidt M,Seyfarth HJ,Ulri

    更新日期:2018-12-01 00:00:00

  • Cardiac effects of acute exhaustive exercise in a rat model.

    abstract:BACKGROUND:The role of physical exercise in the prevention and treatment of cardiovascular diseases has been well described, however, elevations in cardionecrotic biomarkers after prolonged exercise (i.e. ultramarathon running) were observed. We aimed at understanding the biochemical, molecular biological, structural a...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.12.045

    authors: Oláh A,Németh BT,Mátyás C,Horváth EM,Hidi L,Birtalan E,Kellermayer D,Ruppert M,Merkely G,Szabó G,Merkely B,Radovits T

    更新日期:2015-03-01 00:00:00

  • Updated evidence on early statin therapy for acute coronary syndromes: meta-analysis of 18 randomized trials involving over 14,000 patients.

    abstract:BACKGROUND:The short-term effects of early statin therapy in acute coronary syndromes (ACS) on clinical outcomes remain unclear. Our objective was to update the evidence on patient relevant outcomes from all randomized trials comparing early statin therapy with placebo or usual care at 1 and 4 months following ACS. ME...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ijcard.2011.01.033

    authors: Briel M,Vale N,Schwartz GG,de Lemos JA,Colivicchi F,den Hartog FR,Ostadal P,Macin SM,Liem A,Mills E,Bhatnagar N,Bucher HC,Nordmann AJ

    更新日期:2012-06-28 00:00:00

  • Is it safe to use TNF-α blockers for systemic inflammatory disease in patients with heart failure? Importance of dosage and receptor specificity.

    abstract::Tumor necrosis factor-alpha (TNF-α) blockers are widely used in the treatment of chronic inflammatory diseases, especially chronic arthritis. Current guidelines advise against the use of such agents in patients who have a concomitant heart failure. Consequently, a group of patients with a devastating inflammatory dise...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2012.11.112

    authors: Diamantopoulos AP,Larsen AI,Omdal R

    更新日期:2013-09-01 00:00:00

  • Rates and determinants of progressive aortic valve dysfunction in aortic coarctation.

    abstract:PURPOSE:Aortic valve dysfunction is common in coarctation patients(CoA). Bicuspid aortic valve (BAV) in CoA is associated with aortic valve stenosis (AS), aortic valve regurgitation (AR), and ascending aortic dilatation. The aim of this study was to evaluate the progression of and predictors for aortic valve dysfunctio...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2012.07.028

    authors: Luijendijk P,Stevens AW,de Bruin-Bon RH,Boekholdt SM,Vriend JW,Vliegen HW,Bouma BJ,Mulder BJ

    更新日期:2013-09-10 00:00:00

  • Interruption of aortic arch associated with pulmonary valve stenosis.

    abstract::A newborn male is described who presented with interruption of aortic arch associated with ventricular septal defect and pulmonary valve stenosis. He underwent total corrective surgery and was discharged with good clinical results. The combination of significant right ventricular outflow obstruction and interruption o...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(94)02263-i

    authors: Matsushita T,Nakajima T,Kishimoto H

    更新日期:1995-03-24 00:00:00

  • The risk for a first acute coronary syndrome in patients treated with different types of antidepressants: A population based nested case-control study.

    abstract:BACKGROUND:Tricyclic antidepressants (TCAs) are still used in 30% of anxiety/depression cases and have been related to increased cardiovascular risk. Newer serotonin/norepinephrine reuptake inhibitors (SSRIs/SNRIs) safety remains conflicting. Our aim was to assess the risk of a first acute coronary syndrome (ACS) in pa...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2018.04.137

    authors: Almog R,Carasso S,Lavi I,Amir O

    更新日期:2018-09-15 00:00:00

  • Distinct CD11b+-monocyte subsets accelerate endothelial cell recovery after acute and chronic endothelial cell damage.

    abstract:BACKGROUND:Endothelial cell recovery requires replenishment of primary cells from the endothelial lineage. However, recent evidence suggests that cells of the innate immune system enhance endothelial regeneration. METHODS AND RESULTS:Focusing on mature CD11b+-monocytes, we analyzed the fate and the effect of transfuse...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.02.004

    authors: Becher UM,Möller L,Tiyerili V,Vasa Nicotera M,Hauptmann F,Zimmermann K,Pfeifer A,Nickenig G,Wassmann S,Werner N

    更新日期:2014-04-15 00:00:00

  • Cardiac tamponade as presentation of systemic amyloidosis.

    abstract::We present a patient with pericardial tamponade due to amyloid heart disease. A 64-yr-old man was admitted to the hospital because of fatigue and the abrupt development of chest pain and dyspnea. Echocardiography showed severe pericardial effusion and total pericardiectomy was necessary. Ten months later laboratory st...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(92)90115-j

    authors: Navarro JF,Rivera M,Ortuño J

    更新日期:1992-07-01 00:00:00

  • Cross-talk between mineralocorticoid receptor/angiotensin II type 1 receptor and mitogen-activated protein kinase pathways underlies aldosterone-induced atrial fibrotic responses in HL-1 cardiomyocytes.

    abstract:BACKGROUND:Aldosterone is increasingly recognized for its involvement in atrial structural remodeling. However, the precise molecular mechanisms and signal pathways underlying aldosterone-induced atrial fibrosis are unknown. METHODS:Western blotting was used to investigate the effects of aldosterone on the expression ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2013.06.046

    authors: Tsai CF,Yang SF,Chu HJ,Ueng KC

    更新日期:2013-10-25 00:00:00

  • Altered erythrocyte n-3 fatty acids in Mediterranean patients with coronary artery disease.

    abstract::A low frequency of ischaemic heart diseases in Eskimos has been related to polyunsaturated fatty acids. We therefore studied fatty acid patterns associated with coronary artery disease (CAD) for a possible relationship between fatty acid profile and CAD diagnosis in Mediterranean patients. The gas chromatography metho...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/s0167-5273(00)00442-3

    authors: Paganelli F,Maixent JM,Duran MJ,Parhizgar R,Pieroni G,Sennoune S

    更新日期:2001-03-01 00:00:00

  • Gender and age-dependent differences in the bradykinin-degradation within the pericardial fluid of patients with coronary artery disease.

    abstract::Cardiovascular diseases (CVD) and, in particular, coronary artery disease (CAD) are the leading causes of death in developed countries, especially in the elderly population. Males exhibit a higher risk for cardiovascular events than women. The pericardial fluid (PF) is in direct contact with the epicardial sections of...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2009.06.028

    authors: Bechtloff R,Goette A,Bukowska A,Kähne T,Peters B,Huth C,Wolke C,Lendeckel U

    更新日期:2011-01-21 00:00:00

  • Clinical expert consensus document on the use of percutaneous left ventricular assist support devices during complex high-risk indicated PCI: Italian Society of Interventional Cardiology Working Group Endorsed by Spanish and Portuguese Interventional Card

    abstract::Percutaneous coronary intervention (PCI) is establishing as the last remaining revascularization option in an increasing number of patients affected by complex coronary artery disease not suitable for surgery. Over the past decade, percutaneous left ventricular assist device (pLVAD) has increasingly replaced intra-aor...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2019.05.065

    authors: Chieffo A,Burzotta F,Pappalardo F,Briguori C,Garbo R,Masiero G,Nicolini E,Ribichini F,Trani C,Álvarez BC,Leor OR,Moreno R,Santos R,Fiarresga A,Silveira JB,de Prado AP,Musumeci G,Esposito G,Tarantini G

    更新日期:2019-10-15 00:00:00

  • Spatial relationship of sites for atrial fibrillation drivers and atrial tachycardia in patients with both arrhythmias.

    abstract:INTRODUCTION:Atrial fibrillation (AF) often converts to and from atrial tachycardia (AT), but it is undefined if these rhythms are mechanistically related in such patients. We tested the hypothesis that critical sites for AT may be related to regional AF sources in patients with both rhythms, by mapping their locations...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ijcard.2017.07.003

    authors: Baykaner T,Zaman JAB,Rogers AJ,Navara R,AlHusseini M,Borne RT,Park S,Wang PJ,Krummen DE,Sauer WH,Narayan SM

    更新日期:2017-12-01 00:00:00

  • SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy.

    abstract:BACKGROUND:Doxorubicin (DOXO) is an effective anti-neoplastic drug but its clinical benefits are hampered by cardiotoxicity. Oxidative stress, apoptosis and myocardial fibrosis mediate the anthracycline cardiomyopathy. ROS trigger TGF-β pathway that activates cardiac fibroblasts promoting fibrosis. Myocardial stiffness...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.12.008

    authors: Cappetta D,Esposito G,Piegari E,Russo R,Ciuffreda LP,Rivellino A,Berrino L,Rossi F,De Angelis A,Urbanek K

    更新日期:2016-02-15 00:00:00

  • Improved Doppler assessment of the Bjork-Shiley mitral prosthesis using the continuity equation.

    abstract::To assess whether derivation of an effective mitral prosthetic valve area using the continuity equation provides an improved functional assessment of the Bjork-Shiley mitral prosthesis over the pressure half-time method, Doppler echocardiographic studies were performed in 43 patients 12 +/- 7 months following the valv...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(94)90214-3

    authors: Mohan JC,Agrawal R,Arora R,Khalilullah M

    更新日期:1994-03-01 00:00:00

  • Growth differentiation factor 15 and geriatric conditions in acute coronary syndrome.

    abstract:BACKGROUND:Growth differentiation factor 15 (GDF-15) is a marker of cell senescence. Age is a well-known determinant of GDF-15 levels, yet no study has analyzed the relationship between geriatric conditions and GDF-15. We hypothesize that geriatric conditions reflecting biological age might be stronger determinants of ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ijcard.2019.05.034

    authors: Sanchis J,Ruiz V,Bonanad C,Sastre C,Ruescas A,Díaz M,Rodríguez E,Valero E,García-Blas S,Carratalá A,Núñez E,Núñez J

    更新日期:2019-09-01 00:00:00

  • A focused update on emerging prognostic determinants in distal left main percutaneous coronary intervention.

    abstract::A distal location of the atherosclerotic plaque is one of the most powerful predictors of adverse events after left main angioplasty. However, bifurcations are not alike and may differ with regards to a number of variables, including the angle of the bifurcation, the presence of a ramus, the burden of downstream coron...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2011.08.059

    authors: Capodanno D,Calvi V,Tamburino C

    更新日期:2012-09-20 00:00:00

  • Knowledge of native valve anatomy is essential in follow-up of patients after aortic valve replacement.

    abstract:BACKGROUND:After aortic valve replacement (AVR), bicuspid aortic valve (BAV) patients continue to be at risk of aortic complications. Therefore, knowledge of native valve anatomy is important for follow-up. We aimed to determine the extent of which the presence of BAV disease is known in a regional post-AVR population....

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2016.09.084

    authors: Cozijnsen L,van der Zaag-Loonen HJ,Cozijnsen MA,Braam RL,Heijmen RH,Mulder BJ

    更新日期:2016-12-15 00:00:00

  • Primary fibrosarcoma of the heart presenting as obstruction at the tricuspid valve: diagnosis by cross-sectional echocardiography.

    abstract::We report a case of primary fibrosarcoma of the heart which presented with features of obstruction to the tricuspid valve and superior caval vein. It was correctly diagnosed by cross-sectional echocardiography. ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(89)90309-4

    authors: Sethi KK,Nair M,Khanna SK

    更新日期:1989-08-01 00:00:00

  • Effects of angiotensin receptor blocker at discharge in patients with heart failure with reduced ejection fraction: Korean Acute Heart Failure (KorAHF) registry.

    abstract:BACKGROUND:After introduction of up-titration strategy, there are limited data on comparison between the effects of angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blocker (ARB) in patients with heart failure with reduced ejection fraction (HFrEF). The study sought to investigate the associatio...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ijcard.2017.12.002

    authors: Choi KH,Lee GY,Choi JO,Jeon ES,Lee HY,Cho HJ,Lee SE,Kim MS,Kim JJ,Hwang KK,Chae SC,Baek SH,Kang SM,Choi DJ,Yoo BS,Kim KH,Park HY,Cho MC,Oh BH

    更新日期:2018-04-15 00:00:00