Real-time and the in vivo detection of minute cancer invasion to the portal-superior mesenteric vein using contact endoscopy during a pancreatic cancer resection.

Abstract:

:The portal-superior mesenteric vein (PV/SMV) is occasionally involved by a microscopic level of cancer invasion from pancreatic cancer even when it seems to be intact by a macroscopic inspection during surgery. Therefore, contact endoscopy, with which a high-magnification image of the methylene blue-stained PV/SMV wall can be obtained in vivo, was used during pancreatic cancer resections. Contact endoscopy succeeded in detecting minute cancer invasion and identified the precise location on the isolated PV/SMV wall in 3 out of 11 patients whose PV/SMVs had been disclosed from the pancreatic tumors. The 3 positive patients underwent an additional resection of the PV/SMV, and appropriate ranges of PV/SMV resection were confirmed by the postoperative histology. Thus, contact endoscopy is considered a promising modality for making a real-time diagnosis on the precise location of minute cancer, without requiring any tissue sampling.

journal_name

Am J Surg

authors

Eguchi H,Ishikawa O,Ohigashi H,Takahashi H,Ohue M,Takenaka A,Tomita Y,Yano M

doi

10.1016/j.amjsurg.2009.03.009

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

e66-71

issue

5

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(09)00247-5

journal_volume

198

pub_type

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