Abstract：
:Making the right choice depends crucially on the accurate valuation of the available options in the light of current needs and goals of an individual. Thus, the valuation of identical options can vary considerably with motivational context. The present study investigated the neural structures underlying context dependent evaluation. We instructed participants to choose from food menu items based on different criteria: on their anticipated taste or on ease of preparation. The aim of the manipulation was to assess which neural sites were activated during choice guided by incentive value, and which during choice based on a value-irrelevant criterion. To assess the impact of increased motivation, affect-guided choice and cognition-guided choice was compared during the sated and hungry states. During affective choice, we identified increased activity in structures representing primarily valuation and taste (medial prefrontal cortex, insula). During cognitive choice, structures showing increased activity included those implicated in suppression and conflict monitoring (lateral orbitofrontal cortex, anterior cingulate). Hunger influenced choice-related activity in the ventrolateral prefrontal cortex. Our results show that choice is associated with the use of distinct neural structures for the pursuit of different goals.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
Piech RM,Lewis J,Parkinson CH,Owen AM,Roberts AC,Downing PE,Parkinson JAdoi
10.1016/j.bandc.2009.09.012subject
Has Abstractpub_date
2010-03-01 00:00:00pages
282-8issue
2eissn
0278-2626issn
1090-2147pii
S0278-2626(09)00183-3journal_volume
72pub_type
杂志文章abstract：:Extraversion and Neuroticism are two fundamental dimensions of human personality that influence cognitive functioning in healthy subjects. Little is known about personality changes that may occur in patients with multiple sclerosis (MS) nor about, in particular, their neurofunctional basis. The aim of this study is to...
journal_title：Brain and cognition
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journal_title：Brain and cognition
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journal_title：Brain and cognition
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journal_title：Brain and cognition
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doi：10.1016/j.bandc.2006.09.005
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journal_title：Brain and cognition
pub_type： 杂志文章,评审
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journal_title：Brain and cognition
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journal_title：Brain and cognition
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doi：10.1016/j.bandc.2006.10.009
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journal_title：Brain and cognition
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journal_title：Brain and cognition
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journal_title：Brain and cognition
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doi：10.1006/brcg.1993.1010
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journal_title：Brain and cognition
pub_type： 杂志文章
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journal_title：Brain and cognition
pub_type： 杂志文章
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journal_title：Brain and cognition
pub_type： 杂志文章
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journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1006/brcg.2001.1481
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journal_title：Brain and cognition
pub_type： 杂志文章
doi：10.1016/s0278-2626(03)00112-x
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