Abstract：
AIM:To measure contrast-to-noise ratios of liver lesions on conventional enhanced and digitally subtracted multidetector row computed tomography (CT) images. MATERIALS/METHODS:This study was approved by our hospital internal review board (IRB) and all collected data were evaluated in a Health Insurance Portability and Accountability Act (HIPAA)-compliant manner. Subtracted datasets, using pixel-by-pixel subtraction of the post-contrast images from the pre-contrast images, were created from the 64 detector-row CT of patients undergoing three-phase examination of the liver (unenhanced, arterial phase, and portal venous phase). Regions of interest were used to calculate the contrast-to-noise ratios between the lesions and the background liver parenchyma on both the post-contrast and subtracted datasets using the following formula: (Lesion mean (HU) - Liver mean (HU))/standard deviation of mean outside patient (HU). These ratios were compared using a mixed linear statistical model. RESULTS:Contrast-to-noise ratios were calculated for 64 lesions in 50 consecutive patients. Of the 64 lesions, 42 were hypervascular and 22 were hypovascular. Subtracted datasets yielded statistically significant higher contrast-to-noise ratios of hypervascular lesions compared to normal liver parenchyma (p<0.0001). Subtraction did not yield a statistically significant improvement in contrast-to-noise ratios for hypovascular liver lesions (p=0.16). CONCLUSION:Post-processed subtraction CT images generate increased contrast-to-noise ratios for hypervascular liver lesions. As this technique is easy to perform and does not involve additional radiation exposure, it should be considered when evaluating for suspected hypervascular lesions.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Grand DJ,Beland M,Dupuy D,Mayo-Smith WWdoi
10.1016/j.crad.2009.03.013subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1075-80issue
11eissn
0009-9260issn
1365-229Xpii
S0009-9260(09)00245-1journal_volume
64pub_type
杂志文章abstract：AIM:To investigate knowledge of the use of ionizing radiation in 2010 and whether there has been any change in this knowledge since the study was first undertaken over 7 years ago. MATERIALS AND METHODS:In both studies a single chest x-ray was classed as one unit of radiation. Doctors from all grades were asked to eva...
journal_title：Clinical radiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.crad.2011.03.009
更新日期：2011-08-01 00:00:00
abstract：:Abdominal spiral computed tomography (CT) pneumocolon is performed after cleansing the colon, using a smooth muscle relaxant and rectal air insufflation. Rapid dynamic scanning is undertaken with intravenous contrast to give optimal hepatic and vascular enhancement, and 5-10 mm contiguous slices. The area of interest ...
journal_title：Clinical radiology
pub_type：
doi：10.1016/s0009-9260(96)80221-2
更新日期：1996-01-01 00:00:00
abstract：:Labelling leucocytes with 99Tcm using hexamethylpropyleneamine oxime (HMPAO) utilizes the advantages of technetium over indium in imaging inflammation. A retrospective study has been performed on 43 consecutive patients imaged with 99Tcm HMPAO labelled leucocytes in order to assess the reliability of the technique. Pa...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)81933-6
更新日期：1990-09-01 00:00:00
abstract：:This comprehensive review will discuss the classical and unusual radiological features of melorheostosis, which is an uncommon, non-hereditary, benign, sclerosing mesodermal disease with an incidence of 0.9 cases per million. The presentation of melorheostosis in the appendicular skeleton (more commonly involved) and ...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2010.02.004
更新日期：2010-08-01 00:00:00
abstract：AIM:To investigate how spectral computed tomography (SCT) values impact the staging of non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS:One hundred and thirteen patients with confirmed NSCLC were included in a prospective cohort study. All patients underwent single-phase contrast-enhanced SCT (using ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2019.02.010
更新日期：2019-06-01 00:00:00
abstract：AIM:To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings that differentiate solid pseudopapillary carcinomas (SPC) from benign solid pseudopapillary tumours (SPT) of the pancreas. MATERIALS AND METHODS:Preoperative CT or MRI images for 26 patients (eight patients with SPC and 18 patie...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2008.04.007
更新日期：2008-09-01 00:00:00
abstract：AIM:The purpose of this study was to determine the feasibility of echocardiogram (ECG)-gated multi-slice CT angiography (MCTA) in patients with clinical suspicion of acute venous thromboembolism (VTE), to investigate the effect of ECG-gating on cardiac motion artefacts, and to determine the diagnostic reader agreement ...
journal_title：Clinical radiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0009-9260(03)00348-9
更新日期：2003-11-01 00:00:00
abstract：AIM:The purpose of our study was to describe radiological manifestations of tuberculosis in patients with myelodysplastic syndromes. MATERIALS AND METHODS:Chest radiographs and CTs of 12 patients with tuberculosis among 195 consecutive patients with myelodysplastic syndrome, proved by bone marrow biopsy, were reviewed...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1053/crad.2001.0742
更新日期：2002-05-01 00:00:00
abstract：:Currarino et al. in 1981 described an association between an anterior sacral defect, congenital anorectal stenosis or another type of low anorectal malformation and a presacral mass. We are only aware of one previous report in the English literature of the association of a rectovaginal fistula with this triad and to o...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)81859-8
更新日期：1994-04-01 00:00:00
abstract：:Four patients with cervical spine trauma were examined by computerised tomography in addition to standard radiography and additional useful information was thereby gained. The axial projection is particularly useful in studying the cervical spinal canal and neural arch. The examination may be performed rapidly without...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(79)80162-2
更新日期：1979-03-01 00:00:00
abstract：AIM:To evaluate the utility of the elastic ratio calculated using real-time tissue elastography for assessing liver fibrosis in patients with chronic hepatitis B (CHB). MATERIALS AND METHODS:Ninety-six patients with CHB were enrolled between September 2012 and August 2013. The elastic ratio of the liver for the intrah...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2013.10.003
更新日期：2014-02-01 00:00:00
abstract：AIMS:To test the hypothesis that the improved resolution afforded by 16-detector computed tomography (CT) would translate to better stress fracture detection when compared with skeletal scintigraphy. MATERIALS AND METHODS:Thirty-three cases of suspected stress fractures in 26 patients were investigated using skeletal ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2005.05.014
更新日期：2005-10-01 00:00:00
abstract：:Dual-energy (DE) pulmonary blood volume (PBV) computed tomography (CT) has recently become available on clinical CT systems. The underlying physical principle of DECT is the fact that the photoelectric effect is strongly dependent on the CT energies resulting in different degrees of x-ray attenuation for different mat...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2010.12.021
更新日期：2012-01-01 00:00:00
abstract：AIMS:To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS:In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiogr...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2004.04.021
更新日期：2005-01-01 00:00:00
abstract：:The case of a 64-year-old man who presented with unilateral pulsatile exophthalmos is described. A defect in the supero-medial wall of the orbit and an extraconal low density mass were demonstrated by orbital radiographs and CT. Positive contrast CT cisternography confirmed the diagnosis of a leptomeningeal cyst. ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(89)80278-8
更新日期：1989-09-01 00:00:00
abstract：:Twenty-seven patients with a T1 or T2 N0M0 breast carcinoma were treated by local excision of the lump followed by radical radiotherapy, using orthovoltage X-rays. The crude survival rate was 100% at three years, 92% at five years, 95% at 10 years. The local recurrence rate was 8% at three years, 12% at five years, 10...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(81)80246-2
更新日期：1981-01-01 00:00:00
abstract：:Glioblastoma (GBM) is a common brain tumour in adults, which, despite multimodality treatment, has a poor median survival. Efficacy of therapy is assessed by clinical examination and magnetic resonance imaging (MRI) features. There is now a recognised subset of treated patients with imaging features that indicate "pro...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2015.06.096
更新日期：2015-11-01 00:00:00
abstract：:Intrasphenoid internal carotid artery (ICA) pseudoaneurysm can present as and mimic a sinonasal mass. The purpose of this review is to describe the computed tomography (CT) and magnetic resonance imaging (MRI) features that should prompt the radiologist to consider this lesion in the differential diagnosis of a skull ...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/j.crad.2011.12.009
更新日期：2012-08-01 00:00:00
abstract：:We have retrospectively assessed the computed tomography (CT) findings in 92 patients suffering severe blunt abdominal trauma. Surgical findings and clinical follow-up were correlated with the CT findings. In nine patients CT was first used after emergency surgery and provided baseline data which was useful for furthe...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)80373-3
更新日期：1992-11-01 00:00:00
abstract：:Musculoskeletal infection involving the pelvis has rarely been reported in infants. When such infections involve the pelvic muscles they are generally believed to result from secondary spread from adjacent structures. We report five cases of primary pelvic musculoskeletal infection affecting infants <1 year, all of wh...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(97)80160-2
更新日期：1997-10-01 00:00:00
abstract：AIM:To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of inflammatory myofibroblastic tumours (IMTs) of the maxillary sinus. MATERIALS AND METHODS:The imaging findings of eight patients with IMTs of the maxillary sinus were reviewed retrospectively. Of the eight patients, four ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2012.08.002
更新日期：2012-12-01 00:00:00
abstract：AIMS:To describe the optimum conditions for successful free-hand ultrasound guided intervention using an in-vitro experiment. MATERIALS AND METHODS:Optimal free-hand biopsy conditions were determined using targets buried in a purpose-built interventional phantom. The needle/probe distance and probe/phantom surface ang...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1053/crad.2000.0579
更新日期：2001-06-01 00:00:00
abstract：:Three patients with pancreatic clonorchiasis were examined with endoscopic retrograde pancreatography. On each of the three cases there was diffuse irregular dilatation of tributaries of the pancreatic duct in the pancreatic tail. The main pancreatic duct and tributaries draining into the body and head portion were no...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(05)80967-5
更新日期：1990-03-01 00:00:00
abstract：:The modern management of urolithiasis requires a multi-disciplinary approach. Imaging plays a central role in both diagnosis and planning therapy of renal and ureteric calculi. This article reviews the current status of diagnosis and management of stone disease, and the contribution of radiological imaging in accurate...
journal_title：Clinical radiology
pub_type： 杂志文章,评审
doi：10.1016/s0009-9260(03)00103-x
更新日期：2003-06-01 00:00:00
abstract：AIM:To investigate the use of Tc-99m tetrofosmin as a breast imaging agent and to compare results of Tc-99m tetrofosmin scintimammography with plain-film mammography and pathological outcome. PATIENTS AND METHODS:Forty-four patients (mean age, 51 years; range 26-79 years) with a palpable breast mass requiring fine nee...
journal_title：Clinical radiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0009-9260(98)80028-7
更新日期：1998-01-01 00:00:00
abstract：AIM:Recent protein expression profiling of breast cancer has identified specific subtypes with clinical, biological, and therapeutic implications. The aim of this study was to identify the mammographic correlates of these novel molecular classes of invasive breast cancer. MATERIALS AND METHODS:The mammographic finding...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2008.06.006
更新日期：2008-11-01 00:00:00
abstract：:Aneurysm of the ductus arteriosus has been reported in children more frequently than in adults [1-4]. The rarity of the lesion explains the low rate of recognition by the radiologist, especially because symptoms are non-specific in most cases. Clinically and radiologically, aneurysm of the ductal diverticulum can be c...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(97)80279-6
更新日期：1997-03-01 00:00:00
abstract：:The radiopharmaceuticals gallium-67 and indium-111 labelled leucocytes have been compared in 15 patients with a painful joint prosthesis in an attempt to identify those patients with periprosthetic infection. Gallium-67 images were abnormal in five out of six patients with periprosthetic infection and normal in seven ...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(84)80148-8
更新日期：1984-05-01 00:00:00
abstract：:Percutaneous fine needle aspiration biopsy was performed in 38 patients. Adequate material for histological diagnosis was obtained in all. No false positive results were obtained and there was only one false negative result. The procedure was without complication in all patients. The biopsy material was obtained by th...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(80)80068-7
更新日期：1980-09-01 00:00:00
abstract：AIM:To investigate the frequency, clinical significance, and outcome of small-bowel intussusceptions in adults detected using ultrasound in an outpatient setting. PATIENTS AND METHODS:In two different retrospective (January 2001 to April 2003) and prospective (May 2003 to June 2005) periods, 33 small-bowel intussuscep...
journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/j.crad.2007.02.009
更新日期：2007-08-01 00:00:00
