Cognitive and daily functioning in older adults with vegetative symptoms of depression.

Abstract:

OBJECTIVES:In primary care 50-95% of patients with depression present with vegetative symptoms (VS). Based on the extant literature, older adults showing VS (but no dysphoria) may show functional impairment but this hypothesis has not been empirically tested. The goal of this study was to examine neurocognitive and daily functioning of elderly patients showing exclusively VS in comparison with patients presenting with VS and dysphoria. METHODS:Seven hundred and eighty-seven primary care patients received measures of neurocognition and daily functioning. Neurocognition was measured with the repeatable battery for the assessment of neuropsychological status (RBANS). Three groups were compared: (1) patients with two or more VS of depression without dysphoria (VS - D), (2) patients with at least one VS and dysphoria (VS + D), and (3) comparison patients without multiple VS or dysphoria. RESULTS:Nearly one third of the sample (31%) fell into the VS - D group, whereas 15% fell into the VS + D group. Both VS groups showed poorer neurocognition and activities of daily living than comparisons. Only one subtest of the RBANS (i.e., picture naming) showed a significant difference between VS + D and VS - D, and there was no significant difference on daily functioning. VS - D patients reported less frequent past history of depression and endorsed less anxiety compared to VS + D. CONCLUSIONS:Elderly patients presenting with clusters of VS with or without dysphoria show poorer neurocognitive and functional performance. Relative poorer cognition and daily functioning in VS - D are potential harbingers of further decline and consistent with under-reporting of sadness in older age.

authors

Paradiso S,Duff K,Vaidya JG,Hoth A,Mold JW

doi

10.1002/gps.2376

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

569-77

issue

6

eissn

0885-6230

issn

1099-1166

journal_volume

25

pub_type

杂志文章
  • Factors affecting timely recognition and diagnosis of dementia across Europe: from awareness to stigma.

    abstract:BACKGROUND:Timely recognition and diagnosis of dementia is the pre-condition for improving dementia care, but diagnosis often occurs late in the disease process. OBJECTIVE:To compare facilitators and obstacles to the timely recognition of dementia across eight European Union states, in order to implement established p...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.1302

    authors: Vernooij-Dassen MJ,Moniz-Cook ED,Woods RT,De Lepeleire J,Leuschner A,Zanetti O,de Rotrou J,Kenny G,Franco M,Peters V,Iliffe S

    更新日期:2005-04-01 00:00:00

  • Dementia programme effectiveness in long-term care.

    abstract:OBJECTIVE:To examine the effectiveness of dementia programmes and report factors related to programme outcomes. To describe the characteristics which placed hostel residents at risk for nursing home placement and to measure changes in dependencies and impairments over 2 years. DESIGN:Longitudinal, quasi-experimental u...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-1166(199702)12:2<173::aid-gps59

    authors: Rosewarne R,Bruce A,McKenna M

    更新日期:1997-02-01 00:00:00

  • Unrecognised psychological problems impair quality of life and increase consultation rates in Chinese elderly patients.

    abstract:OBJECTIVE:Studies have shown that psychological problems in elderly patients are often unrecognised in primary care. The aim of this study was to investigate the quality of life and consultation rates of Chinese elderly patients with unrecognised psychological problems in primary care. The prevalence and risk factors o...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.2210

    authors: Lam CL,Chin WY,Lee PW,Lo YY,Fong DY,Lam TP

    更新日期:2009-09-01 00:00:00

  • Proton magnetic resonance spectroscopy in dementia of Alzheimer type.

    abstract::Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-1166(199703)12:3<349::aid-gps50

    authors: Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

    更新日期:1997-03-01 00:00:00

  • Social network types and cognitive decline among older Korean adults: A longitudinal population-based study.

    abstract:OBJECTIVES:Social network (SN) has been known to impact on cognitive function in late life. However, knowledge regarding the link between SN of various types and cognitive decline (CD) is limited. This study's aim was to investigate which types of SN are associated with reduced risk of CD 2 years later among community-...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5200

    authors: Kim YB,Lee SH

    更新日期:2019-12-01 00:00:00

  • Screening for cognitive dysfunction in Huntington's disease with the clock drawing test.

    abstract:BACKGROUND:The aim of the study is to investigate the performance of the clock drawing test as a screening tool for cognitive impairment in Huntington's disease (HD) mutation carriers. METHODS:The performance of the clock drawing test was assessed in 65 mutation carriers using the Shulman and the Freund scoring system...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4412

    authors: Terwindt PW,Hubers AA,Giltay EJ,van der Mast RC,van Duijn E

    更新日期:2016-09-01 00:00:00

  • Quantitative EEG in progressing vs stable mild cognitive impairment (MCI): results of a 1-year follow-up study.

    abstract:OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2042

    authors: Luckhaus C,Grass-Kapanke B,Blaeser I,Ihl R,Supprian T,Winterer G,Zielasek J,Brinkmeyer J

    更新日期:2008-11-01 00:00:00

  • Drinking behavior among older adults in a planned retirement community: results from The Villages survey.

    abstract:OBJECTIVES:Research indicates increasing trends among older adults toward heavy and abusive drinking, often associated with depressive symptoms. Possible exceptions are residents of planned retirement communities, whose drinking may be associated with social activities. To better understand these relationships, this st...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4359

    authors: Fishleder S,Schonfeld L,Corvin J,Tyler S,VandeWeerd C

    更新日期:2016-05-01 00:00:00

  • White matter lesions and temporal atrophy are associated with cognitive and neuropsychiatric symptoms in patients with hypertension and Alzheimer's disease.

    abstract:OBJECTIVES:An increasing evidence suggests hypertension (HTN) could be linked to cognitive impairment and incident Alzheimer's disease (AD). The precise mechanisms linking HTN and AD are not well-known. The aim of this study was to assess the putative association between HTN and AD. METHODS:We assessed in patients wit...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5366

    authors: García-Alberca JM,Mendoza S,Gris E,Royo JL,Cruz-Gamero JM,García-Casares N

    更新日期:2020-11-01 00:00:00

  • Patterns of late-life depressive symptoms and subsequent declines in cognitive domains.

    abstract:BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4618

    authors: Gillis JC,Chang SC,Devore EE,Rosner BA,Grodstein F,Okereke OI

    更新日期:2017-12-01 00:00:00

  • Factors for predicting reversion from mild cognitive impairment to normal cognition: A meta-analysis.

    abstract:OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/gps.5159

    authors: Xue H,Hou P,Li Y,Mao X,Wu L,Liu Y

    更新日期:2019-10-01 00:00:00

  • Prevalence of dementia in a rural setting: A report from India.

    abstract::A study to estimate the prevalence of dementia in a rural population was conducted in a community located on the outskirts of Madras city in South India. Seven hundred and fifty elderly 60 years of age and older, selected using the cluster sampling technique, were interviewed using the Geriatric Mental State schedule ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 社论

    doi:10.1002/(sici)1099-1166(199707)12:7<702::aid-gps48

    authors: Rajkumar S,Kumar S,Thara R

    更新日期:1997-07-01 00:00:00

  • Change in cognitive functioning in depressed older adults following treatment with sertraline or nortriptyline.

    abstract:OBJECTIVE:The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults. METHODS:We used pre-post neuropsychological data collected as part of a 12-week medication trial comparing sertraline to nortriptyline in the treatment of older adults ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/gps.2783

    authors: Culang-Reinlieb ME,Sneed JR,Keilp JG,Roose SP

    更新日期:2012-08-01 00:00:00

  • Deliberate self-harm in older people revisited.

    abstract:BACKGROUND:Deliberate self harm (DSH) in later life is under researched and is believed to be related to both mental illness and suicide. AIMS:The aim of the study was to examine deliberate self-harm (DSH) in older people presenting to acute hospital services over three years. METHOD:This was a retrospective observat...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.1404

    authors: Lamprecht HC,Pakrasi S,Gash A,Swann AG

    更新日期:2005-11-01 00:00:00

  • Factors affecting withdrawal and donation attrition in the brains for dementia research cohort.

    abstract:OBJECTIVES:To measure two forms of attrition in a cohort of volunteer brain donors: Withdrawal during life and non-donation at death. To test whether cognitive impairment independently predicts attrition. METHOD:Attrition rates were calculated for all registered participants and for all brain donors who had completed ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4975

    authors: Costello H,Hayes GM,Francis PT

    更新日期:2018-12-01 00:00:00

  • Cognitive impairment in late life schizophrenia and bipolar I disorder.

    abstract:OBJECTIVE:Evidence in younger populations suggests quantitative but not categorical differences in cognitive impairments between schizophrenia and bipolar disorder. It is uncertain whether a similar distinction applies to patients in later life. METHODS:We compared the cognitive abilities of older, community-living sc...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.3793

    authors: Meesters PD,Schouws S,Stek M,de Haan L,Smit J,Eikelenboom P,Beekman A,Comijs H

    更新日期:2013-01-01 00:00:00

  • Effectiveness of group reminiscence therapy for depressive symptoms in male veterans: 6-month follow-up.

    abstract:OBJECTIVE:The purpose of this study was to use group reminiscence therapy (GRT) as a nursing intervention to evaluate the post-test, 3-month and 6-month effects on depressive symptoms for institutionalised male veterans after a 4-week intervention. METHODS:A quasi-experimental design and purposive sampling was conduct...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4013

    authors: Chueh KH,Chang TY

    更新日期:2014-04-01 00:00:00

  • Test Your Memory test: diagnostic utility in a memory clinic population.

    abstract:BACKGROUND:Test Your Memory (TYM) test is a recently described cognitive test instrument designed to be self-administered under medical supervision. The pragmatic role of such self-administered tests in cognitive clinics has not previously been examined. We investigated the diagnostic utility of the TYM as an independe...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2639

    authors: Hancock P,Larner AJ

    更新日期:2011-09-01 00:00:00

  • Clinical predictors of response to Acetyl Cholinesterase Inhibitors: experience from routine clinical use in Newcastle.

    abstract:BACKGROUND:Acetyl Cholinesterase Inhibitors (AChEIs) have been in clinical use for the past five years in the UK for the symptomatic treatment of Alzheimer's disease (AD). There are few data on the patterns and predictors of response to AChEI therapy in routine clinical practice. We therefore investigated clinical vari...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.928

    authors: Pakrasi S,Mukaetova-Ladinska EB,McKeith IG,O'Brien JT

    更新日期:2003-10-01 00:00:00

  • What help do GPs want from specialist services in managing patients with dementia?

    abstract::The views of GPs about psychiatric services for dementia were obtained by questionnaire survey. Provision of adequate long term care, together with support for both family carers and healthcare workers were strongly stated needs. Other needs were rapid access to care, clear diagnosis, special needs of young patients w...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/1099-1166(200008)15:8<758::aid-gps295>3.0.

    authors: Williams I

    更新日期:2000-08-01 00:00:00

  • Adverse events of repetitive transcranial magnetic stimulation in older adults with depression, a systematic review of the literature.

    abstract:OBJECTIVE:In the last decade, repetitive transcranial magnetic stimulation (rTMS) has been introduced as a non-invasive neuromodulation therapy for depression. Little is known, however, about (serious) adverse events (AE) of rTMS in older adults with a depression. In this article, we want to study what is known about (...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,评审

    doi:10.1002/gps.5440

    authors: Overvliet GM,Jansen RAC,van Balkom AJLM,van Campen DC,Oudega ML,van der Werf YD,van Exel E,van den Heuvel OA,Dols A

    更新日期:2020-10-09 00:00:00

  • Safety and tolerability of rivastigmine capsule with memantine in patients with probable Alzheimer's disease: a 26-week, open-label, prospective trial (Study ENA713B US32).

    abstract:OBJECTIVE:Rivastigmine, a dual cholinesterase inhibitor (ChEI), is widely approved for the symptomatic treatment of both mild-to-moderate Alzheimer's disease (AD) and Parkinson's disease dementia. Orally administered ChEIs may be associated with gastrointestinal (GI) side effects and add-on therapy with memantine, an N...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.2355

    authors: Olin JT,Bhatnagar V,Reyes P,Koumaras B,Meng X,Brannan S

    更新日期:2010-04-01 00:00:00

  • Shortness of breath as a predictor of depressive symptoms in a community sample of older adults.

    abstract:OBJECTIVES:Physical symptoms are known to be associated with late life depression both cross-sectionally and over time. We attempted to determine if self-reported shortness of breath (SoB) is associated with depressive symptoms at long-term (3-year) follow-up in a community sample of older (65+) adults. METHODS:A samp...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.2477

    authors: Blazer DG,Hybels CF

    更新日期:2010-10-01 00:00:00

  • Access to public mental health services among older adults with severe mental illness.

    abstract:OBJECTIVE:Limited data are available on how older adults access public mental health systems. This study examines how uninsured or publicly insured older adults with severe mental illness in San Diego County initially accessed the public mental health system, as well as their subsequent use of public mental health serv...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2123

    authors: Gilmer TP,Ojeda VD,Fuentes D,Criado V,Garcia P

    更新日期:2009-03-01 00:00:00

  • Early parental death and psychosocial risk factors for dementia: A case-control study in Europe.

    abstract:OBJECTIVES:To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. METHODS/DESIGN:A population-based case-control study of a sample of 65 997 participants from the Survey of H...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5328

    authors: Conde-Sala JL,Garre-Olmo J

    更新日期:2020-09-01 00:00:00

  • Differences in suicide behaviour in the elderly: a study in two provinces of Northern Italy.

    abstract:BACKGROUND:to investigate the suicide phenomenon among the elderly (people aged 65 and over) in the Italian provinces of Novara and Verbania, in the time span between January 1990 and December 2000, in order to evaluate if the characteristics of the suicide behaviour correlate to the place of living with particular att...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.1354

    authors: Zeppegno P,Manzetti E,Valsesia R,Siliquini R,Ammirata G,De Donatis O,Usai C,Torre E

    更新日期:2005-08-01 00:00:00

  • Big Five personality characteristics are associated with depression subtypes and symptom dimensions of depression in older adults.

    abstract:OBJECTIVE:This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS:Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were as...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4670

    authors: Koorevaar AML,Hegeman JM,Lamers F,Dhondt ADF,van der Mast RC,Stek ML,Comijs HC

    更新日期:2017-12-01 00:00:00

  • Relationship between white matter T2 hyperintensity and cortical volume changes on magnetic resonance imaging in healthy elders.

    abstract:OBJECTIVE:T2 white matter hyperintensity (WMH) on magnetic resonance imaging (MRI) is associated with brain atrophy. Some previous studies examined the relation between the WMH and cortical atrophy, however, little is known about how the WMHs affect the pattern of cortical atrophy. Recent studies have revealed that pat...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2618

    authors: Ota M,Nemoto K,Sato N,Mizukami K,Yamashita F,Asada T

    更新日期:2011-09-01 00:00:00

  • Costs of dementia and dementia care: a review.

    abstract::Costs of dementia care constitute a great part of the total costs of care for elderly. Because the prevalence of dementia is linked to increasing age, and the number of the oldest old is rising, the costs of dementia care will increase considerably in the forthcoming decades. In this review, research describing costs ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,评审

    doi:

    authors: Wimo A,Ljunggren G,Winblad B

    更新日期:1997-08-01 00:00:00

  • Apathy and depression in Alzheimer's disease are associated with functional deficit and psychotropic prescription.

    abstract:BACKGROUND:Apathy and depression are the most common neuropsychiatric features in Alzheimer's disease (AD). The clinical and functional specific correlates of these syndromes are not well known independently from cognitive deficits and other behavioral disturbances. MATERIAL AND METHODS:Six hundred and eighty-six pati...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.1895

    authors: Benoit M,Andrieu S,Lechowski L,Gillette-Guyonnet S,Robert PH,Vellas B,REAL-FR group.

    更新日期:2008-04-01 00:00:00