Uric acid: a novel risk factor for acute kidney injury in high-risk cardiac surgery patients?

abstract：BACKGROUND:The prognostic value of the anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis (GN) classification has been demonstrated in several cohorts with sclerotic class having the worst renal outcome. Relevant published data on factors predicting outcomes in sclerotic ANCA GN is limited. METH...

journal_title：American journal of nephrology

authors： Menez S,Hruskova Z,Scott J,Cormican S,Chen M,Salama AD,Alasfar S,Little MA,Safrankova H,Honsova E,Tesar V,Geetha D

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In autosomal dominant polycystic kidney disease, renoprotective treatment with a vasopressin V2 receptor antagonist (V2RA) is given in a fixed dose (FD). Disease progression and drug habituation could diminish treatment efficacy. We investigated whether the renoprotective effect of the V2RA can be improved b...

journal_title：American journal of nephrology

authors： Zittema D,Versteeg IB,Gansevoort RT,van Goor H,de Heer E,Veraar KA,Peters DJ,Meijer E

更新日期：2016-01-01 00:00:00

abstract：:Serum levels of soluble interleukin-2 receptors (IL2R) and of beta 2-microglobulin (beta 2M) were studied with the immunoenzymatic technique in 38 patients with primary glomerulonephritis (GN), in 10 patients with essential hypertension (EH) and in 30 healthy subjects. IL2R correlated with beta 2M (p < 0.05). IL2R and...

journal_title：American journal of nephrology

authors： Rollino C,Roccatello D,Amprimo MC,Cavalli G,Aimo G,Beltrame G,Basolo B,Martina G,Piccoli G

更新日期：1993-01-01 00:00:00

abstract：:We have compared the renal effects of ioxitalamate, ioxaglate, and iopamidol in patients with chronic renal failure. Sixty consecutive patients with an estimated creatinine clearance (ECRCl) less than 60 ml/min were randomly assigned to receive either ioxitalamate, iopamidol, or ioxaglate. All patients received 500 cm...

journal_title：American journal of nephrology

authors： Deray G,Bellin MF,Boulechfar H,Baumelou B,Koskas F,Baumelou A,Grellet J,Jacobs C

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with chronic renal failure (CRF) secondary to diabetes mellitus show a high incidence of atherosclerosis with its thrombotic complications. Both CRF and type 2 diabetes mellitus (DM2) results in fibrinolysis defects causally related to atherogenesis and thrombogenesis. It is not well known whet...

journal_title：American journal of nephrology

authors： Opatrný K Jr,Zemanová P,Mares J,Vít L,Opatrná S,Sefrna F,Hejda V,Tomsů M,Eiselt J,Massry SG

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal injury. The ubiquitous protein annexin A1 (ANXA1) has potent anti-inflammatory effects and protects a...

journal_title：American journal of nephrology

authors： Araujo LP,Truzzi RR,Mendes GE,Luz MA,Burdmann EA,Oliani SM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:The mesothelium of patients undergoing peritoneal dialysis (PD) is exposed to glucose in dialysate. Glucose metabolites 3-deoxyglucosone and advanced glycation endproducts (AGEs) in the PD fluid induce peritoneal damage. Circulating factors also affect the peritoneum in the uremic model and predialysis ...

journal_title：American journal of nephrology

authors： Hasuike Y,Moriguchi R,Hata R,Miyagawa K,Kuragano T,Aizawa M,Yamamoto S,Yanase K,Izumi M,Tanimoto T,Nakanishi T

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) impairs intestinal barrier function which by allowing influx of noxious products causes systemic inflammation. We have recently shown that intestinal barrier dysfunction in CKD is due to degradation of epithelial tight junction (TJ) which is, in part, mediated by influx of urea a...

journal_title：American journal of nephrology

authors： Vaziri ND,Yuan J,Khazaeli M,Masuda Y,Ichii H,Liu S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cisplatin (CIS) induces nephrotoxicity partly through renal vasoconstriction and decreased glomerular filtration effects thought to involve adenosine acting on adenosine A(1) receptors (A1Rs). We studied the effect of the orally active, A1R antagonist tonapofylline (BG9928) on biochemical measures of re...

journal_title：American journal of nephrology

authors： Gill A,Wortham K,Costa D,Davis W,Ticho B,Whalley E

更新日期：2009-01-01 00:00:00

abstract：:Forty-eight chronic hemodialysis patients were divided comparably into two groups (24 patients in each). Two micrograms of 1 alpha(OH)D3 was administered to one group for 3 months and its placebo to the other group. In the 1 alpha(OH)D3-treated group, serum total calcium increased from 7.82 +/- 0.11 (mean +/- SEM) to ...

journal_title：American journal of nephrology

authors： Shimamatsu K,Onoyama K,Fujimi S,Iseki K,Fujishima M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND AIM:Robust evidence about dialyzer reuse effects on mortality is not available. Our aim was to summarize the evidence for the effectiveness of dialyzer reuse compared to single use in patients with end-stage renal disease. METHODS:We searched MEDLINE, Embase, CINAHL, SciELO, LILACS, USRDS ADR, universit...

journal_title：American journal of nephrology

authors： Galvao TF,Silva MT,Araujo ME,Bulbol WS,Cardoso AL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Overt albuminuria (urinary albumin-creatinine ratio [ACR] > 300 mg/g) is an established risk factor for progression of nephropathy and total mortality. However, whether a reduction in ACR translates into a reduction in mortality and/or cardiovascular (CV) events among insulin-treated patients with type 2 dia...

journal_title：American journal of nephrology

authors： Anyanwagu U,Donnelly R,Idris I

更新日期：2019-01-01 00:00:00

abstract：AIM:To develop and assess a semiautomated method for segmenting and counting individual renal cysts from mid-slice MR images in patients with autosomal dominant polycystic kidney disease (ADPKD). METHODS:A semiautomated method was developed to segment and count individual renal cysts from mid-slice MR images in 241 su...

journal_title：American journal of nephrology

authors： Bae KT,Sun H,Lee JG,Bae K,Wang J,Tao C,Chapman AB,Torres VE,Grantham JJ,Mrug M,Bennett WM,Flessner MF,Landsittel DP,Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease.

更新日期：2014-01-01 00:00:00

abstract：:Investigations of biopsy material from human kidneys with different forms of glomerulonephritis (n = 1,240) and with diabetic glomerulosclerosis (n = 406) performed in order to find changes caused by hyperperfusion of the kidney tissue gave the following results: (1) Hyperperfusion injury occurs in the different forms...

journal_title：American journal of nephrology

authors： Bohle A,Biwer E,Christensen JA

更新日期：1988-01-01 00:00:00

abstract：:In this paper, we analyze the collection of ancient Greek treatises ascribed to Hippocrates (460; between 371 and 350 BC), in order to determine whether or not edema can be traced. As a result of reading these works on the Greek text, we recognize some symptoms of edema in those called oidêma (swelling) and udrôps (dr...

journal_title：American journal of nephrology

authors： Touwaide A,De Santo NG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Evidence suggests that recombinant human erythropoietin (rHuEPO) protects neurons and cardiomyocytes from acute insults. We investigated the protective effect of rHuEPO on cyclosporine (CsA)-induced renal injury. METHODS:CsA (15 mg/kg/day) was given to rats for 1 or 4 weeks, and rHuEPO was concurrently admi...

journal_title：American journal of nephrology

authors： Lee SH,Li C,Lim SW,Ahn KO,Choi BS,Kim YS,Moon IS,Kim J,Bang BK,Yang CW

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The value of chronic kidney disease (CKD) screening in the general population remains unclear but may be beneficial in populations with high disease prevalence. We examined risk factors for albuminuria among participants in a state-wide CKD screening program in Hawaii. METHODS:The National Kidney Foundation...

journal_title：American journal of nephrology

authors： Wong LL,Kalantar-Zadeh K,Page V,Hayashida G,You AS,Rhee CM

更新日期：2017-01-01 00:00:00

abstract：:Renal function and life expectancy can be improved by aggressive antihypertensive therapy in severe hypertension. However, most reports of severe hypertension and renal failure concern primary hypertensive states. 3 cases of primary renal disease, 1 glomerular, 1 obstructive and 1 of chronic pyelonephritis, are descri...

journal_title：American journal of nephrology

authors： Friedlaender MM,Rubinger D,Popovtzer MM

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Contemporary prevalence of chronic kidney disease (CKD) and thrombotic cardiovascular (CV) events remains unclear in Veterans enrolled in the Veterans Affairs Health Care System (VA) care. Although oral P2Y12 inhibitors (P2Y12i) are increasingly being prescribed to this patient population, the overall prescr...

journal_title：American journal of nephrology

authors： Singh M,Raghavan D,Williams JS,Martin BC,Hudson TJ,Owen RR,Jain N

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Apoptosis contributes to cyclosporine (CsA)-induced renal cell death. This study tested the effects of CsA-induced endoplasmic reticulum (ER) stress on apoptotic cell death in an experimental model of chronic CsA nephropathy. METHODS:CsA (15 mg/kg per day) was given to rats for 7 or 28 days. The ER str...

journal_title：American journal of nephrology

authors： Han SW,Li C,Ahn KO,Lim SW,Song HG,Jang YS,Cho YM,Jang YM,Ghee JY,Kim JY,Kim SH,Kim J,Kwon OJ,Yang CW

更新日期：2008-01-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) inhibitor therapy has recently been shown to be effective in the treatment of post-renal transplant erythrocytosis (PTE). In an attempt to assess the effect of drug treatment on serum erythropoietin level, glomerular filtration rate, and urinary protein excretion, we prospectively e...

journal_title：American journal of nephrology

authors： Mulhern JG,Lipkowitz GS,Braden GL,Madden RL,O'Shea MH,Harvilchuck H,Guarnera JM,Germain MJ

更新日期：1995-01-01 00:00:00

abstract：:Heavy proteinuria in patients with essential hypertension raises the question of underlying primary renal disease. While malignant hypertension may be associated with proteinuria in the nephrotic range, it is generally held that protein excretion in benign nephrosclerosis is almost invariably less than 0.5-1.0 g/24 h....

journal_title：American journal of nephrology

authors： Mujais SK,Emmanouel DS,Kasinath BS,Spargo BH

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Most studies evaluating predictors of renal replacement therapy (RRT) following cardiac surgery use arbitrary defined limits of preoperative serum creatinine. The aim of this study was to evaluate the effect of preoperative renal function using either estimated-glomerular filtration rate (eGFR) derived using...

journal_title：American journal of nephrology

authors： Drosos G,Ampatzidou F,Sarafidis P,Karaiskos T,Madesis A,Boutou AK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:A poor nutritional state is associated with an increased risk of cardiovascular events in end-stage renal disease. It is unclear whether malnutrition itself can induce cardiovascular disease (CVD). We examined the impact of nutritional status on patients' arterial stiffness in peritoneal dialysis (PD) patien...

journal_title：American journal of nephrology

authors： Tang W,Cheng LT,Lu XH,Wang T

更新日期：2009-01-01 00:00:00

abstract：:Hemolytic-uremic syndrome following quinine ingestion is a newly described phenomenon, with just two previous descriptions of 4 cases in the literature. We describe a 5th case. The reaction may be mediated by the presence of antibodies reactive against platelets in the presence of quinine. Treatment has included use o...

journal_title：American journal of nephrology

authors： Hagley MT,Hosney IA,Hulisz DT,Davis HH

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:This study aimed at evaluating the after effects of a single bout of aerobic exercise on muscle sympathetic nerve activity (MSNA), peripheral vascular resistance and blood pressure (BP) in stages 2-3 chronic kidney disease (CKD) patients. We hypothesized that CKD patients present a greater decline in these v...

journal_title：American journal of nephrology

authors： Aprile DC,Oneda B,Gusmão JL,Costa LA,Forjaz CL,Mion D Jr,Tinucci T

更新日期：2016-01-01 00:00:00

abstract：:Accelerated atherosclerosis is both a cause and a consequence of chronic renal failure. Vascular smooth muscle cells (VSMCs) are an important component of atherosclerotic plaques, responsible for promoting plaque stability in advanced lesions. In contrast, VSMC apoptosis has been implicated in a number of deleterious ...

journal_title：American journal of nephrology

authors： Clarke M,Bennett M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIMS:Living donor nephrectomy can be associated with increases in blood pressure several years following the procedure, but the best method to assess blood pressure during the living donor evaluation process is unclear. METHODS:Living kidney donors underwent casual clinic and ambulatory blood pressure monit...

journal_title：American journal of nephrology

authors： DeLoach SS,Meyers KE,Townsend RR

更新日期：2012-01-01 00:00:00

abstract：:Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after earl...

journal_title：American journal of nephrology

authors： Tang S,Cheng CC,Tse KC,Li FK,Choy BY,Chan TM,Lai KN

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Anthropometric parameters may play a role in modulating the risk of kidney dysfunction. The aim of this study was to evaluate whether anthropometric indices and the metabolic syndrome are associated with alterations of the renal resistive index (RI) in normoalbuminuric type 2 diabetic (T2DM) patients. METHOD...

journal_title：American journal of nephrology

authors： Lamacchia O,Nicastro V,Camarchio D,Stallone G,Gesualdo L,Cignarelli M

更新日期：2008-01-01 00:00:00