Abstract:
:Specific reading disability is an example of a complex behavioral disorder which is clinically heterogeneous. It is probably also heterogeneous at the levels of etiology and process (pathogenesis), but there may not be a 1:1:1 mapping of etiology to process to clinical outcome. Thus, classification of cases by clinical features may not lead to discovery of the underlying processes or etiologies, and it may be profitable to define subgroups by etiology. There is evidence for genetic etiology in some cases, but there is genetic heterogeneity as well. Possible genetic models for specific reading disability include polygenic, oligogenic, and single gene inheritance, and there are several types of genetic analysis that can be used to determine which of these modes of inheritance may be present. Identification of individual genes is possible in single gene and oligogenic disorders. Clinical studies and molecular analysis can then be used to determine gene function.
journal_name
J Am Acad Child Adolesc Psychiatryauthors
Smith SD,Pennington BF,Kimberling WJ,Ing PSdoi
10.1097/00004583-199003000-00008subject
Has Abstractpub_date
1990-03-01 00:00:00pages
204-13issue
2eissn
0890-8567issn
1527-5418pii
S0890-8567(09)65509-Xjournal_volume
29pub_type
杂志文章abstract:OBJECTIVE:To evaluate the relative efficacy of (1) individual cognitive-behavioral family-based therapy (CBFT); (2) group CBFT; and (3) a waitlist control group in the treatment of childhood obsessive-compulsive disorder (OCD). METHOD:This study, conducted at a university clinic in Brisbane, Australia, involved 77 chi...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-200401000-00014
更新日期:2004-01-01 00:00:00
abstract::Sixteen Tourette's syndrome patients, aged 9 to 15 years, whose symptoms were not controlled with neuroleptics, were followed for various lengths of time after the application of a transdermal nicotine patch (TNP) (7 mg/24 hours) as part of an ongoing case study. While there was a broad range in individual response, a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章
doi:10.1097/00004583-199612000-00015
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:Over half of the world's refugee population are under the age of 18 years. This systematic review aims to summarize the current body of evidence for the prevalence of mental illness in child and adolescent refugee populations. METHOD:Eight electronic databases, gray literature, and Google Scholar were search...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2019.11.011
更新日期:2020-06-01 00:00:00
abstract::For several decades, national surveys and reports have well documented the serious, growing, and unmet need for mental and behavioral health services among children, adolescents, and young adults (C/A/YA) in the United States.1-3 Moreover, shortages and maldistribution of child and adolescent psychiatrists have been r...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 社论
doi:10.1016/j.jaac.2019.09.028
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:Growing awareness that symptoms of autism spectrum disorder (ASD) transcend multiple diagnostic categories, and major advances in the identification of genetic syndromes associated with ASD, have led to widespread use of ASD symptom measures in etiologic studies of neurodevelopmental disorders. Insufficient c...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2016.09.490
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To review the evidence for qualitatively distinct subtypes of human aggression as they relate to childhood psychopathology. METHOD:Critical review of the pertinent literature. RESULTS:In humans, as well as in animals, the term aggression encompasses a variety of behaviors that are heterogeneous for clinical...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199703000-00008
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:To describe the development and summarize the psychometric properties of the Children's Interview for Psychiatric Syndromes (ChIPS). METHOD:ChIPS is a highly structured interview designed for use by trained lay interviewers in children aged 6-18 years. It screens for 20 Axis I disorders as well as psychosoci...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200001000-00019
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To review findings on attention-deficit/hyperactivity disorder and attention problems (AP) in children, adolescents, and adults, as established in the database of the Netherlands Twin Register and increase the understanding of stability in AP across the lifespan as a function of genetic and environmental infl...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.jaac.2012.10.009
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The consequences of bullying are well described, yet little is known about protective factors that may diminish the negative sequelae. One possible factor, physical activity (PA), improves mental health in general and clinical populations. The purpose of this study is to examine relationships among PA, sadnes...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2015.06.019
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To clarify the diagnostic significance of selective mutism (elective mutism in DSM-III-R). METHOD:Fifty children with selective mutism were evaluated systematically by means of semistructured clinical interviews and rating scales to obtain detailed diagnostic information. RESULTS:All 50 children met DSM-III...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199705000-00016
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:To conduct a placebo-controlled study of the effectiveness of a universal school-based depression prevention program. METHOD:Three hundred ninety-two students age 13 to 15 from two schools were randomized to intervention (RAP-Kiwi) and placebo programs run by teachers. RAP-Kiwi was an 11-session manual-based...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004583-200405000-00007
更新日期:2004-05-01 00:00:00
abstract::Japanese society strongly influences the mode of presentation of child mental health problems, both in terms of protective factors and pressures inherent in Japanese child-rearing practices. Recent changes in society associated with Japan's rapid economic development are affecting the mental health of children and fam...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-198907000-00003
更新日期:1989-07-01 00:00:00
abstract:OBJECTIVES:To describe the level of self-esteem among the study population, to examine how self-esteem ratings may vary by disorder characteristics and medication use, and to identify predictors of low self-esteem while adjusting for sociodemographic factors. METHOD:In a school district-wide sample of children in spec...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200010000-00013
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The authors studied the hemispheric functioning of adolescents with attention-deficit hyperactivity disorder (ADHD) in relation to this group's response to positively toned emotional stimuli. METHOD:Dichotic word tests were used to measure perceptual asymmetry in 21 adolescent inpatients and 24 control subje...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199303000-00012
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:To review the literature on pediatric obsessive-compulsive disorder (OCD) from the perspective of information relevant to American Board of Psychiatry and Neurology recertification in child and adolescent psychiatry. METHOD:The clinical and research literatures were systematically searched or articles that a...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,评审
doi:10.1097/00004583-199610000-00012
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:This study examined associations between age of menarche and psychosocial outcomes in early adulthood, including sexual behavior, mental health, criminal behavior, and education/employment, to identify the possible causal role of earlier age of menarche in increasing risks of adverse outcomes. METHOD:Data we...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2010.11.007
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:Clinical research depends on the participation of representative samples. At the 2001 Annual Meeting of the American Academy of Child and Adolescent Psychiatry, the Workgroup on Research conducted a research forum with the purpose of improving recruitment and retention of children and adolescents in research ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type:
doi:10.1097/01.chi.0000129222.89433.3d
更新日期:2004-08-01 00:00:00
abstract::"Behavioral inhibition to the unfamiliar" is a temperamental construct reflecting the tendency to be shy, timid, and constrained in novel situations. Previous work has suggested that it may be associated with anxiety disorders in children. Psychopathology was assessed in children from a nonclinical sample originally i...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199201000-00016
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Child maltreatment is associated with dysregulation of stress-mediating systems and an increased risk of mental and physical health problems. Specifically, disruptions in hypothalamic-pituitary-adrenal (HPA) axis regulation have been reported in maltreated children. The current study investigates whether incr...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2014.08.006
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To assess the course and outcome of anorexia nervosa (AN) and bulimia nervosa (BN) at a median of 90 months of follow-up in a large cohort of women with eating disorders. METHOD:A prospective, naturalistic, longitudinal design was used to map the course of AN and BN in 246 women. Follow-up data are presented...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199907000-00012
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:Neuroimaging studies have identified distinct neural correlates of obsessive-compulsive disorder (OCD) symptom dimensions in adult subjects and may be related to functional abnormalities in different cortico-striatal-thalamic neural systems underlying cognition and affective processing. Similar symptom dimens...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e3181b2163c
更新日期:2009-09-01 00:00:00
abstract::The still-face procedure, in which mothers maintain a neutral face and are noninteractive with their infants, has been used to study the effects of maternal withdrawal on the mother-infant interaction. In this study, 56 mothers' reactions to their own experience during a still-face procedure were explored using an ope...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199101000-00004
更新日期:1991-01-01 00:00:00
abstract::As clinicians, we have been vigilant to screen for underlying psychopathology in children and adolescents who meet criteria for gender dysphoria (GD) based on the risk these individuals have for developing externalizing and/or internalizing disorders, likely driven by a stigmatizing society. However, we have not paid ...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 评论,社论
doi:10.1016/j.jaac.2018.05.001
更新日期:2018-07-01 00:00:00
abstract::To assess children's mental health service needs and utilization patterns for a state planning effort, a cross-sectional survey that sampled 822 children aged 6 to 11 of a metropolitan center was conducted. When reports of parents and teachers were combined, 38.5% of children were screened to be at risk of psychiatric...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199209000-00025
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:Abnormal stereotyped behaviors are a significant problem for many individuals with mental retardation or mental illness. To increase understanding of the development of abnormal stereotyped behaviors, the authors investigated the early rhythmic behaviors of children at increased risk for developmental delays....
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200201000-00013
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To examine the hypothesis that autism spectrum disorders (ASD) diagnosis and traits in childhood are associated with suicidal thoughts, plans and self-harm at 16 years, and that any observed associations are explained by depression at 12 years. METHOD:We examined associations between ASD diagnosis and 4 dich...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1016/j.jaac.2018.01.023
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:This study examines the potential role of candidate genes in moderating treatment effects of methylphenidate (MPH) in attention-deficit/hyperactivity disorder (ADHD). METHOD:Eighty-two subjects with ADHD aged 6 to 17 years participated in a prospective, double-blind, placebo-controlled, multiple-dose, crosso...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/CHI.0b013e3181bc72e3
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between time reproduction, performance variability, and sustained attention deficits in children with attention-deficit/hyperactivity disorder (ADHD) combined (ADHD-C) and inattentive (ADHD-I) subtypes, relative to matched controls. METHOD:Participants (age range 7.1-14.1 years) p...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-200502000-00009
更新日期:2005-02-01 00:00:00
abstract::There are few reports of the behavioral manifestations in the pediatric population infected with human immunodeficiency virus type 1 (HIV-1). We report a case of a 4-year-old child with acquired immunodeficiency syndrome, whose initial manifestation of central nervous system involvement consisted of sudden onset of im...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章
doi:10.1097/00004583-199503000-00014
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVES:The primary objective of the study was to assess whether the Availability, Responsiveness and Continuity (ARC) organizational intervention improved youth outcomes in community based mental health programs. The second objective was to assess whether programs with more improved organizational social contexts f...
journal_title:Journal of the American Academy of Child and Adolescent Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jaac.2013.02.005
更新日期:2013-05-01 00:00:00